Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37825998 . C A CCDS11343.1:NM_002686.4:c.319Cgc>Agc_NP_002677.1:p.107R>S Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1hnn 1 P11086 100.0 0.0 X-RAY
 2001-12-07 ARG A:107 A:107 45.0 0.2 H -49.7 -34.1 45.0 0.2 0.0 SAH
HOH
 7.150
3.168
 N
NH2
 O3'
O
ARG B:107 B:607 57.0 0.253 H -59.0 -25.1 NA NA NA
1n7i 1 P11086 100.0 0.0 X-RAY
 2003-12-23 ARG A:107 A:107 39.0 0.173 H -46.8 -40.3 39.0 0.173 0.0 SAH
HOH
 7.608
8.369
 N
O
 O3'
O
ARG B:107 B:607 56.0 0.249 H -51.8 -40.7 NA NA NA
1n7j 1 P11086 100.0 0.0 X-RAY
 2003-12-23 ARG A:107 A:107 43.0 0.191 H -52.8 -35.2 43.0 0.191 0.0 SAH
HOH
 7.545
3.741
 N
NH1
 O3'
O
ARG B:107 B:607 60.0 0.267 H -59.4 -32.4 NA NA NA
6ws1 1 P11086 100.0 0.0 X-RAY
 2020-08-05 ARG A:119 A:107 48.0 0.213 H -56.3 -32.5 48.0 0.213 0.0 SAH
 7.715
 NH1
 O2'
ARG B:119 B:107 56.0 0.249 H -55.2 -34.7 56.0 0.249 0.0 U87
EDO
HOH
 7.675
6.155
5.747
 N
NH1
NH1
 O3'
C2
O
1yz3 1 P11086 100.0 0.0 X-RAY
 2006-02-07 ARG A:107 A:107 54.0 0.24 H -59.9 -30.1 54.0 0.24 0.0 SAH
HOH
 7.584
2.902
 N
NE
 O3'
O
ARG B:107 B:107 52.0 0.231 H -67.2 -29.3 52.0 0.231 0.0 SAH
HOH
 7.509
2.829
 NH1
O
 O2'
O
2an3 1 P11086 100.0 0.0 X-RAY
 2006-03-14 ARG A:107 A:107 44.0 0.196 H -54.8 -31.8 44.0 0.196 0.0 SAH
HOH
 7.376
3.101
 N
NH2
 O3'
O
ARG B:107 B:607 51.0 0.227 H -63.1 -33.8 NA NA NA
2an4 1 P11086 100.0 0.0 X-RAY
 2006-03-14 ARG A:107 A:107 40.0 0.178 H -55.4 -34.8 40.0 0.178 0.0 SAH
HOH
 7.321
3.388
 N
NH2
 O3'
O
ARG B:107 B:107 52.0 0.231 H -58.8 -40.7 NA NA NA
2an5 1 P11086 100.0 0.0 X-RAY
 2006-03-14 ARG A:107 A:107 42.0 0.187 H -55.1 -36.6 42.0 0.187 0.0 SAH
HOH
 7.357
3.417
 N
NH2
 O3'
O
ARG B:107 B:107 50.0 0.222 H -56.4 -42.9 NA NA NA
2g70 1 P11086 100.0 0.0 X-RAY
 2007-02-13 ARG A:107 A:107 38.0 0.169 H -67.1 -21.0 38.0 0.169 0.0 SAM
HOH
 7.565
8.246
 N
O
 O3'
O
ARG B:107 B:107 56.0 0.249 H -59.9 -24.3 NA NA NA
2g71 1 P11086 100.0 0.0 X-RAY
 2007-02-13 ARG A:107 A:107 50.0 0.222 H -63.0 -34.5 50.0 0.222 0.0 SAH
HOH
 7.479
2.725
 N
NE
 O3'
O
ARG B:107 B:107 53.0 0.236 H -60.2 -31.6 NA NA NA
2g72 1 P11086 100.0 0.0 X-RAY
 2007-02-13 ARG A:107 A:107 46.0 0.204 H -60.5 -31.9 46.0 0.204 0.0 SAM
HOH
 7.466
2.729
 N
NE
 O3'
O
ARG B:107 B:107 56.0 0.249 H -59.7 -31.1 NA NA NA
2g8n 1 P11086 100.0 0.0 X-RAY
 2006-09-12 ARG A:107 A:107 56.0 0.249 H -60.7 -32.9 56.0 0.249 0.0 SAH
HOH
 7.554
3.049
 N
NE
 O3'
O
ARG B:107 B:107 56.0 0.249 H -61.5 -31.7 NA NA NA
2ony 1 P11086 100.0 0.0 X-RAY
 2007-10-09 ARG A:107 A:107 44.0 0.196 H -66.6 -32.9 44.0 0.196 0.0 SAH
HOH
 7.572
3.600
 N
NH2
 O3'
O
ARG B:107 B:607 54.0 0.24 H -61.6 -27.8 NA NA NA
3hcb 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ARG A:107 A:107 46.0 0.204 H -71.6 -32.3 46.0 0.204 0.0 SAH
 7.755
 N
 O3'
ARG B:107 B:107 52.0 0.231 H -63.0 -40.3 NA NA NA
3hcc 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ARG A:107 A:107 39.0 0.173 H -63.1 -32.8 39.0 0.173 0.0 SAH
HOH
 7.644
3.026
 N
NH2
 O3'
O
ARG B:107 B:107 52.0 0.231 H -59.8 -36.0 NA NA NA
3hcd 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ARG A:107 A:107 43.0 0.191 H -55.0 -39.9 43.0 0.191 0.0 SAH
HOH
 7.254
3.228
 N
NH2
 O3'
O
ARG B:107 B:107 52.0 0.231 H -58.5 -40.5 NA NA NA
3hcf 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ARG A:107 A:107 40.0 0.178 H -50.7 -31.4 40.0 0.178 0.0 SAH
HOH
 7.484
3.551
 N
NH2
 O3'
O
ARG B:107 B:107 49.0 0.218 H -51.8 -44.6 NA NA NA
3kpj 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 40.0 0.178 H -62.1 -37.9 40.0 0.178 0.0 SAH
HOH
 7.620
3.098
 NH1
NH2
 O2'
O
ARG B:107 B:107 51.0 0.227 H -63.0 -40.9 51.0 0.227 0.0 SAH
HOH
 7.702
3.056
 N
NE
 O2'
O
3kpu 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 45.0 0.2 H -58.5 -34.8 45.0 0.2 0.0 SAH
HOH
 7.751
2.613
 N
NE
 O3'
O
ARG B:107 B:107 57.0 0.253 H -60.8 -37.5 57.0 0.253 0.0 SAH
HOH
 7.603
2.818
 N
O
 O3'
O
3kpv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 48.0 0.213 H -62.2 -38.8 48.0 0.213 0.0 SAH
HOH
 7.559
3.222
 N
NH2
 O3'
O
ARG B:107 B:107 53.0 0.236 H -57.9 -38.4 53.0 0.236 0.0 SAH
HOH
 7.675
2.881
 N
O
 O3'
O
3kpw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 43.0 0.191 H -62.7 -36.1 43.0 0.191 0.0 SAH
HOH
 7.740
3.807
 N
NH1
 O3'
O
ARG B:107 B:107 53.0 0.236 H -59.3 -37.8 53.0 0.236 0.0 SAH
HOH
 7.575
3.034
 N
NE
 O3'
O
3kpy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 45.0 0.2 H -65.0 -34.3 45.0 0.2 0.0 SAH
HOH
 7.654
4.432
 N
NH1
 O3'
O
ARG B:107 B:107 56.0 0.249 H -58.8 -33.3 56.0 0.249 0.0 SAH
HOH
 7.566
2.860
 N
O
 O3'
O
3kqm 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 46.0 0.204 H -65.0 -37.8 46.0 0.204 0.0 SAH
HOH
 7.722
4.217
 N
NH1
 O3'
O
ARG B:107 B:107 52.0 0.231 H -61.9 -36.6 52.0 0.231 0.0 SAH
HOH
 7.716
3.210
 N
O
 O3'
O
3kqo 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 46.0 0.204 H -67.2 -31.0 46.0 0.204 0.0 SAH
HOH
 7.725
2.909
 N
NE
 O3'
O
ARG B:107 B:107 57.0 0.253 H -59.2 -37.5 57.0 0.253 0.0 SAH
HOH
 7.709
2.838
 N
O
 O3'
O
3kqp 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 39.0 0.173 H -60.7 -33.8 39.0 0.173 0.0 SAH
HOH
 7.579
4.267
 N
NH1
 O3'
O
ARG B:107 B:107 53.0 0.236 H -63.2 -34.3 53.0 0.236 0.0 SAH
HOH
 7.590
4.977
 N
NH2
 O3'
O
3kqq 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 45.0 0.2 H -59.8 -39.0 45.0 0.2 0.0 SAH
HOH
 7.643
4.460
 N
NH2
 O3'
O
ARG B:107 B:107 56.0 0.249 H -54.7 -43.2 56.0 0.249 0.0 SAH
HOH
 7.623
2.900
 N
NE
 O3'
O
3kqs 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 48.0 0.213 H -60.8 -34.0 48.0 0.213 0.0 SAH
HOH
 7.675
2.845
 N
NE
 O3'
O
ARG B:107 B:107 58.0 0.258 H -59.9 -34.8 58.0 0.258 0.0 SAH
HOH
 7.694
2.900
 N
O
 O3'
O
3kqt 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 49.0 0.218 H -62.2 -33.9 49.0 0.218 0.0 SAH
HOH
 7.686
4.997
 N
NH2
 O3'
O
ARG B:107 B:107 53.0 0.236 H -60.8 -32.1 53.0 0.236 0.0 SAH
HOH
 7.705
2.935
 N
NE
 O3'
O
3kqv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 46.0 0.204 H -62.1 -33.3 46.0 0.204 0.0 SAH
HOH
 7.690
2.855
 N
O
 O3'
O
ARG B:107 B:107 55.0 0.244 H -58.4 -37.6 55.0 0.244 0.0 SAH
HOH
 7.663
2.935
 N
NH2
 O3'
O
3kqw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 45.0 0.2 H -62.0 -33.2 45.0 0.2 0.0 SAH
HOH
 7.609
3.589
 N
NH1
 O3'
O
ARG B:107 B:107 54.0 0.24 H -62.0 -30.6 54.0 0.24 0.0 SAH
HOH
 7.591
2.938
 N
NH2
 O3'
O
3kqy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 45.0 0.2 H -65.2 -31.8 45.0 0.2 0.0 SAH
HOH
 7.701
3.007
 N
NH2
 O3'
O
ARG B:107 B:107 56.0 0.249 H -59.9 -34.9 56.0 0.249 0.0 SAH
HOH
 7.582
2.907
 N
NH2
 O3'
O
3kr0 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 44.0 0.196 H -56.8 -36.9 44.0 0.196 0.0 SAH
HOH
 7.643
6.514
 N
N
 O3'
O
ARG B:107 B:107 53.0 0.236 H -55.8 -39.2 53.0 0.236 0.0 SAH
HOH
 7.584
2.806
 N
NE
 O3'
O
3kr1 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 45.0 0.2 H -64.3 -31.0 45.0 0.2 0.0 SAH
HOH
 7.621
3.261
 N
NH2
 O3'
O
ARG B:107 B:107 55.0 0.244 H -59.9 -36.1 55.0 0.244 0.0 SAH
HOH
 7.606
2.781
 N
NH2
 O3'
O
3kr2 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:107 A:107 46.0 0.204 H -63.9 -34.1 46.0 0.204 0.0 SAH
HOH
 7.764
4.588
 N
NH2
 O3'
O
ARG B:107 B:107 52.0 0.231 H -60.4 -33.5 52.0 0.231 0.0 SAH
HOH
 7.610
2.889
 N
O
 O3'
O
4dm3 1 P11086 100.0 0.0 X-RAY
 2012-04-25 ARG A:107 A:107 48.0 0.213 H -63.7 -32.5 48.0 0.213 0.0 SAH
HOH
 7.723
2.747
 N
NE
 O3'
O
ARG B:107 B:107 56.0 0.249 H -60.6 -33.0 56.0 0.249 0.0 SAH
HOH
 7.575
2.606
 N
NH2
 O3'
O
4mik 1 P11086 100.0 0.0 X-RAY
 2014-09-10 ARG A:107 A:107 46.0 0.204 H -58.8 -32.8 46.0 0.204 0.0 JIL
TRS
HOH
 7.112
9.555
1.948
 H
HG2
HE
 H011
H12
O
ARG B:107 B:107 55.0 0.244 H -55.8 -35.4 55.0 0.244 0.0 JIL
TRS
HOH
 6.859
9.376
2.014
 H
N
HH22
 H011
H22
O
4mq4 1 P11086 100.0 0.0 X-RAY
 2014-10-15 ARG A:107 A:107 45.0 0.2 H -60.3 -33.9 45.0 0.2 0.0 2D5
TRS
HOH
 6.536
9.396
2.131
 HG3
HG2
HH22
 H171
H22
O
ARG B:107 B:107 42.0 0.187 H -60.6 -34.1 42.0 0.187 0.0 2D5
TRS
HOH
 7.139
9.550
2.944
 H
HA
O
 H151
H31
O
3hca 1 P11086 99.65 0.0 X-RAY
 2009-08-25 ARG A:107 A:107 48.0 0.213 H -60.3 -37.6 48.0 0.213 0.0 SAH
HOH
 7.393
2.903
 N
NH2
 O3'
O
ARG B:107 B:107 55.0 0.244 H -58.3 -34.2 NA NA NA
3hce 1 P11086 99.65 0.0 X-RAY
 2009-08-25 ARG A:107 A:107 44.0 0.196 H -56.6 -30.0 44.0 0.196 0.0 SAH
HOH
 7.597
3.032
 N
NH2
 O3'
O
ARG B:107 B:107 52.0 0.231 H -53.4 -31.7 NA NA NA
2obf 1 P11086 99.65 0.0 X-RAY
 2007-10-09 ARG A:107 A:107 49.0 0.218 H -58.7 -33.5 49.0 0.218 0.0 SAH
HOH
 7.572
2.772
 N
NE
 O3'
O
ARG B:107 B:607 57.0 0.253 H -55.2 -35.2 NA NA NA
2onz 1 P11086 99.65 0.0 X-RAY
 2007-10-09 ARG A:107 A:107 48.0 0.213 H -55.5 -31.8 48.0 0.213 0.0 SAH
HOH
 7.486
2.935
 N
NE
 O3'
O
ARG B:107 B:607 50.0 0.222 H -57.3 -33.5 NA NA NA
2opb 1 P11086 99.65 0.0 X-RAY
 2007-10-09 ARG A:107 A:107 55.0 0.244 H -54.8 -31.1 55.0 0.244 0.0 SAH
HOH
 7.444
2.978
 N
NH2
 O3'
O
ARG B:107 B:107 53.0 0.236 H -60.0 -27.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11086-f1 1 P11086 100.0 0.0 ARG A:107 A:107 52.0 0.231 H -58.7 -37.3