Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37826013 . C A CCDS11343.1:NM_002686.4:c.334Cgc>Agc_NP_002677.1:p.112R>S Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1hnn 1 P11086 100.0 0.0 X-RAY
 2001-12-07 ARG A:112 A:112 67.0 0.298 H -54.7 -40.6 67.0 0.298 0.0 HOH
 6.309
 C
 O
ARG B:112 B:612 83.0 0.369 H -71.8 -40.8 NA NA NA
1n7i 1 P11086 100.0 0.0 X-RAY
 2003-12-23 ARG A:112 A:112 72.0 0.32 H -47.1 -32.2 72.0 0.32 0.0 HOH
 4.605
 CB
 O
ARG B:112 B:612 77.0 0.342 H -60.8 -44.1 NA NA NA
1n7j 1 P11086 100.0 0.0 X-RAY
 2003-12-23 ARG A:112 A:112 80.0 0.356 H -56.7 -34.6 80.0 0.356 0.0 HOH
 8.732
 O
 O
ARG B:112 B:612 83.0 0.369 H -67.8 -44.4 NA NA NA
6ws1 1 P11086 100.0 0.0 X-RAY
 2020-08-05 ARG A:124 A:112 58.0 0.258 H -72.0 -26.2 58.0 0.258 0.0
ARG B:124 B:112 88.0 0.391 H -55.6 -21.9 88.0 0.391 0.0 HOH
 8.588
 O
 O
1yz3 1 P11086 100.0 0.0 X-RAY
 2006-02-07 ARG A:112 A:112 67.0 0.298 H -60.5 -29.7 67.0 0.298 0.0 HOH
 4.468
 CB
 O
ARG B:112 B:112 73.0 0.324 H -65.7 -42.0 73.0 0.324 0.0 HOH
 3.341
 N
 O
2an3 1 P11086 100.0 0.0 X-RAY
 2006-03-14 ARG A:112 A:112 68.0 0.302 H -58.3 -35.5 68.0 0.302 0.0 HOH
 4.468
 CB
 O
ARG B:112 B:612 79.0 0.351 H -66.5 -43.6 NA NA NA
2an4 1 P11086 100.0 0.0 X-RAY
 2006-03-14 ARG A:112 A:112 70.0 0.311 H -60.3 -21.0 70.0 0.311 0.0 HOH
 4.379
 CB
 O
ARG B:112 B:112 82.0 0.364 H -68.5 -37.8 NA NA NA
2an5 1 P11086 100.0 0.0 X-RAY
 2006-03-14 ARG A:112 A:112 66.0 0.293 H -63.0 -31.7 66.0 0.293 0.0 HOH
 5.731
 O
 O
ARG B:112 B:112 82.0 0.364 H -65.1 -35.6 NA NA NA
2g70 1 P11086 100.0 0.0 X-RAY
 2007-02-13 ARG A:112 A:112 57.0 0.253 H -55.6 -29.8 57.0 0.253 0.0 HOH
 4.664
 CB
 O
ARG B:112 B:112 60.0 0.267 H -69.1 -35.7 NA NA NA
2g71 1 P11086 100.0 0.0 X-RAY
 2007-02-13 ARG A:112 A:112 61.0 0.271 H -57.9 -30.0 61.0 0.271 0.0 HOH
 4.073
 NH2
 O
ARG B:112 B:112 85.0 0.378 H -60.5 -40.0 NA NA NA
2g72 1 P11086 100.0 0.0 X-RAY
 2007-02-13 ARG A:112 A:112 64.0 0.284 H -60.3 -31.2 64.0 0.284 0.0 HOH
 4.497
 CB
 O
ARG B:112 B:112 85.0 0.378 H -69.8 -38.6 NA NA NA
2g8n 1 P11086 100.0 0.0 X-RAY
 2006-09-12 ARG A:112 A:112 68.0 0.302 H -60.2 -35.8 68.0 0.302 0.0 HOH
 4.379
 CB
 O
ARG B:112 B:112 78.0 0.347 H -67.6 -39.8 NA NA NA
2ony 1 P11086 100.0 0.0 X-RAY
 2007-10-09 ARG A:112 A:112 69.0 0.307 H -53.5 -38.6 69.0 0.307 0.0 HOH
 3.106
 CD
 O
ARG B:112 B:612 77.0 0.342 H -81.7 -31.2 NA NA NA
3hcb 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ARG A:112 A:112 69.0 0.307 H -57.9 -35.1 69.0 0.307 0.0
ARG B:112 B:112 97.0 0.431 H -63.9 -38.9 NA NA NA
3hcc 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ARG A:112 A:112 66.0 0.293 H -62.3 -28.9 66.0 0.293 0.0 HOH
 4.025
 NE
 O
ARG B:112 B:112 79.0 0.351 H -64.6 -48.7 NA NA NA
3hcd 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ARG A:112 A:112 72.0 0.32 H -61.2 -30.1 72.0 0.32 0.0 HOH
 3.318
 NE
 O
ARG B:112 B:112 84.0 0.373 H -70.1 -34.4 NA NA NA
3hcf 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ARG A:112 A:112 78.0 0.347 H -48.5 -39.5 78.0 0.347 0.0 HOH
 7.939
 O
 O
ARG B:112 B:112 82.0 0.364 H -65.4 -46.9 NA NA NA
3kpj 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 73.0 0.324 H -51.8 -33.8 73.0 0.324 0.0 HOH
 2.958
 NE
 O
ARG B:112 B:112 77.0 0.342 H -67.5 -35.3 77.0 0.342 0.0 HOH
 4.561
 CB
 O
3kpu 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 69.0 0.307 H -61.9 -37.1 69.0 0.307 0.0 HOH
 4.071
 NH2
 O
ARG B:112 B:112 80.0 0.356 H -63.4 -35.6 80.0 0.356 0.0 HOH
 3.434
 NH2
 O
3kpv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 61.0 0.271 H -56.0 -39.9 61.0 0.271 0.0 HOH
 4.560
 O
 O
ARG B:112 B:112 74.0 0.329 H -68.0 -36.4 74.0 0.329 0.0 HOH
 3.355
 N
 O
3kpw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 69.0 0.307 H -57.5 -35.5 69.0 0.307 0.0 HOH
 3.702
 NH2
 O
ARG B:112 B:112 84.0 0.373 H -65.9 -37.4 84.0 0.373 0.0 HOH
 3.856
 NH1
 O
3kpy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 70.0 0.311 H -60.4 -35.3 70.0 0.311 0.0 HOH
 3.888
 O
 O
ARG B:112 B:112 74.0 0.329 H -68.8 -39.1 74.0 0.329 0.0 HOH
 3.541
 N
 O
3kqm 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 67.0 0.298 H -53.2 -33.5 67.0 0.298 0.0 HOH
 4.446
 CB
 O
ARG B:112 B:112 80.0 0.356 H -79.5 -37.1 80.0 0.356 0.0 HOH
 5.787
 CD
 O
3kqo 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 62.0 0.276 H -60.2 -35.8 62.0 0.276 0.0 HOH
 2.618
 NH2
 O
ARG B:112 B:112 76.0 0.338 H -72.5 -37.7 76.0 0.338 0.0 HOH
 2.593
 NE
 O
3kqp 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 69.0 0.307 H -61.6 -35.0 69.0 0.307 0.0 HOH
 7.145
 O
 O
ARG B:112 B:112 78.0 0.347 H -73.2 -31.6 78.0 0.347 0.0 HOH
 4.230
 CB
 O
3kqq 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 66.0 0.293 H -52.1 -41.4 66.0 0.293 0.0 HOH
 4.412
 CB
 O
ARG B:112 B:112 78.0 0.347 H -67.5 -33.6 78.0 0.347 0.0 HOH
 3.637
 NH1
 O
3kqs 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 73.0 0.324 H -60.0 -40.6 73.0 0.324 0.0 HOH
 2.620
 NH2
 O
ARG B:112 B:112 77.0 0.342 H -65.0 -41.2 77.0 0.342 0.0 HOH
 2.578
 NE
 O
3kqt 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 67.0 0.298 H -54.4 -36.6 67.0 0.298 0.0 HOH
 2.512
 NH2
 O
ARG B:112 B:112 79.0 0.351 H -66.7 -43.1 79.0 0.351 0.0 HOH
 2.761
 NE
 O
3kqv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 70.0 0.311 H -56.7 -40.6 70.0 0.311 0.0 HOH
 3.644
 NH2
 O
ARG B:112 B:112 79.0 0.351 H -64.6 -41.8 79.0 0.351 0.0 HOH
 2.802
 CD
 O
3kqw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 68.0 0.302 H -49.8 -39.9 68.0 0.302 0.0 HOH
 5.558
 NE
 O
ARG B:112 B:112 75.0 0.333 H -74.9 -35.2 75.0 0.333 0.0 HOH
 2.773
 NE
 O
3kqy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 67.0 0.298 H -56.9 -38.8 67.0 0.298 0.0 HOH
 2.943
 CD
 O
ARG B:112 B:112 83.0 0.369 H -66.4 -43.6 83.0 0.369 0.0 HOH
 2.543
 NE
 O
3kr0 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 66.0 0.293 H -60.0 -34.9 66.0 0.293 0.0 HOH
 2.695
 CD
 O
ARG B:112 B:112 80.0 0.356 H -59.4 -45.0 80.0 0.356 0.0 HOH
 3.391
 NH1
 O
3kr1 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 67.0 0.298 H -59.4 -34.9 67.0 0.298 0.0 HOH
 4.346
 CB
 O
ARG B:112 B:112 82.0 0.364 H -65.1 -44.4 82.0 0.364 0.0 HOH
 4.313
 CB
 O
3kr2 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:112 A:112 65.0 0.289 H -54.0 -35.9 65.0 0.289 0.0 HOH
 4.375
 CB
 O
ARG B:112 B:112 81.0 0.36 H -64.0 -40.3 81.0 0.36 0.0 HOH
 2.715
 NE
 O
4dm3 1 P11086 100.0 0.0 X-RAY
 2012-04-25 ARG A:112 A:112 67.0 0.298 H -58.2 -30.1 67.0 0.298 0.0 HOH
 4.364
 CB
 O
ARG B:112 B:112 73.0 0.324 H -67.8 -36.8 73.0 0.324 0.0 HOH
 3.499
 N
 O
4mik 1 P11086 100.0 0.0 X-RAY
 2014-09-10 ARG A:112 A:112 66.0 0.293 H -61.2 -36.5 66.0 0.293 0.0 HOH
 3.193
 HH21
 O
ARG B:112 B:112 77.0 0.342 H -59.3 -41.7 77.0 0.342 0.0 HOH
 1.692
 HH22
 O
4mq4 1 P11086 100.0 0.0 X-RAY
 2014-10-15 ARG A:112 A:112 75.0 0.333 H -58.5 -37.6 75.0 0.333 0.0 HOH
 1.704
 HH22
 O
ARG B:112 B:112 63.0 0.28 H -59.8 -32.4 63.0 0.28 0.0 HOH
 3.906
 HB2
 O
3hca 1 P11086 99.65 0.0 X-RAY
 2009-08-25 ARG A:112 A:112 69.0 0.307 H -59.7 -37.7 69.0 0.307 0.0 HOH
 2.632
 NH2
 O
ARG B:112 B:112 89.0 0.396 H -71.6 -32.4 NA NA NA
3hce 1 P11086 99.65 0.0 X-RAY
 2009-08-25 ARG A:112 A:112 68.0 0.302 H -52.1 -38.6 68.0 0.302 0.0 HOH
 4.893
 CB
 O
ARG B:112 B:112 80.0 0.356 H -68.6 -41.0 NA NA NA
2obf 1 P11086 99.65 0.0 X-RAY
 2007-10-09 ARG A:112 A:112 67.0 0.298 H -53.9 -36.8 67.0 0.298 0.0 HOH
 3.476
 NE
 O
ARG B:112 B:612 75.0 0.333 H -69.9 -39.7 NA NA NA
2onz 1 P11086 99.65 0.0 X-RAY
 2007-10-09 ARG A:112 A:112 67.0 0.298 H -58.9 -37.6 67.0 0.298 0.0 HOH
 5.427
 N
 O
ARG B:112 B:612 80.0 0.356 H -70.1 -35.0 NA NA NA
2opb 1 P11086 99.65 0.0 X-RAY
 2007-10-09 ARG A:112 A:112 59.0 0.262 H -46.3 -41.5 59.0 0.262 0.0 HOH
 7.918
 O
 O
ARG B:112 B:112 80.0 0.356 H -63.2 -45.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11086-f1 1 P11086 100.0 0.0 ARG A:112 A:112 52.0 0.231 H -59.2 -45.5