Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37826077 . T A CCDS11343.1:NM_002686.4:c.398aTt>aAt_NP_002677.1:p.133I>N Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1hnn 1 P11086 100.0 0.0 X-RAY
 2001-12-07 ILE A:133 A:133 52.0 0.297 H -58.6 -40.8 52.0 0.297 0.0 HOH
 5.284
 CD1
 O
ILE B:133 B:633 56.0 0.32 H -67.2 -39.0 NA NA NA
1n7i 1 P11086 100.0 0.0 X-RAY
 2003-12-23 ILE A:133 A:133 54.0 0.309 H -63.7 -43.9 54.0 0.309 0.0 HOH
 8.075
 CD1
 O
ILE B:133 B:633 77.0 0.44 H -78.0 -27.5 NA NA NA
1n7j 1 P11086 100.0 0.0 X-RAY
 2003-12-23 ILE A:133 A:133 59.0 0.337 H -54.1 -43.8 59.0 0.337 0.0 HOH
 7.637
 CD1
 O
ILE B:133 B:633 68.0 0.389 H -63.4 -43.0 NA NA NA
6ws1 1 P11086 100.0 0.0 X-RAY
 2020-08-05 ILE A:145 A:133 48.0 0.274 H -77.8 -44.5 47.0 0.269 0.005 B:P11086:0.006
 EDO
EDO
HOH
 3.486
7.042
9.934
 O
O
O
 C1
O1
O
ILE B:145 B:133 55.0 0.314 H -71.7 -40.4 51.0 0.291 0.023 A:P11086:0.023
 EDO
HOH
 9.805
7.280
 O
O
 C2
O
1yz3 1 P11086 100.0 0.0 X-RAY
 2006-02-07 ILE A:133 A:133 50.0 0.286 H -63.4 -50.3 50.0 0.286 0.0 HOH
 3.820
 CD1
 O
ILE B:133 B:133 57.0 0.326 H -81.0 -16.7 57.0 0.326 0.0 HOH
 2.967
 O
 O
2an3 1 P11086 100.0 0.0 X-RAY
 2006-03-14 ILE A:133 A:133 55.0 0.314 H -63.9 -42.5 55.0 0.314 0.0 HOH
 3.621
 CG2
 O
ILE B:133 B:633 58.0 0.331 H -80.0 -22.6 NA NA NA
2an4 1 P11086 100.0 0.0 X-RAY
 2006-03-14 ILE A:133 A:133 58.0 0.331 H -66.7 -40.9 58.0 0.331 0.0 HOH
 3.397
 CG2
 O
ILE B:133 B:133 57.0 0.326 H -81.9 -17.5 NA NA NA
2an5 1 P11086 100.0 0.0 X-RAY
 2006-03-14 ILE A:133 A:133 53.0 0.303 H -58.3 -49.9 53.0 0.303 0.0 HOH
 3.515
 O
 O
ILE B:133 B:133 60.0 0.343 H -80.5 -16.4 NA NA NA
2g70 1 P11086 100.0 0.0 X-RAY
 2007-02-13 ILE A:133 A:133 51.0 0.291 H -64.4 -43.3 51.0 0.291 0.0 HOH
 5.303
 CD1
 O
ILE B:133 B:133 61.0 0.349 H -85.6 -22.6 NA NA NA
2g71 1 P11086 100.0 0.0 X-RAY
 2007-02-13 ILE A:133 A:133 53.0 0.303 H -64.6 -45.8 53.0 0.303 0.0 FTS
HOH
 9.802
3.355
 CD1
CD1
 F3
O
ILE B:133 B:133 60.0 0.343 H -83.0 -21.3 NA NA NA
2g72 1 P11086 100.0 0.0 X-RAY
 2007-02-13 ILE A:133 A:133 48.0 0.274 H -64.2 -47.3 48.0 0.274 0.0 HOH
 5.552
 CD1
 O
ILE B:133 B:133 55.0 0.314 H -85.1 -24.3 NA NA NA
2g8n 1 P11086 100.0 0.0 X-RAY
 2006-09-12 ILE A:133 A:133 46.0 0.263 H -66.3 -44.9 46.0 0.263 0.0 F83
HOH
 8.394
3.907
 CD1
O
 CL1
O
ILE B:133 B:133 55.0 0.314 H -85.1 -19.9 NA NA NA
2ony 1 P11086 100.0 0.0 X-RAY
 2007-10-09 ILE A:133 A:133 48.0 0.274 H -56.4 -55.0 48.0 0.274 0.0 TMJ
HOH
 8.229
3.608
 CD1
O
 CL1
O
ILE B:133 B:633 58.0 0.331 H -90.7 -15.1 NA NA NA
3hcb 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ILE A:133 A:133 57.0 0.326 H -63.7 -49.0 57.0 0.326 0.0
ILE B:133 B:133 60.0 0.343 H -81.8 -18.4 NA NA NA
3hcc 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ILE A:133 A:133 56.0 0.32 H -67.5 -37.3 56.0 0.32 0.0 HOH
 3.349
 CD1
 O
ILE B:133 B:133 58.0 0.331 H -89.4 -18.7 NA NA NA
3hcd 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ILE A:133 A:133 51.0 0.291 H -68.9 -42.9 51.0 0.291 0.0 HOH
 3.656
 CD1
 O
ILE B:133 B:133 52.0 0.297 H -87.4 -26.2 NA NA NA
3hcf 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ILE A:133 A:133 52.0 0.297 H -67.2 -44.5 52.0 0.297 0.0 HOH
 3.234
 O
 O
ILE B:133 B:133 52.0 0.297 H -104.4 -13.3 NA NA NA
3kpj 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 52.0 0.297 H -64.7 -46.4 52.0 0.297 0.0 HOH
 6.831
 C
 O
ILE B:133 B:133 54.0 0.309 H -84.1 -27.5 50.0 0.286 0.023 A:P11086:0.023
 HOH
 3.529
 CG2
 O
3kpu 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 53.0 0.303 H -67.3 -33.3 52.0 0.297 0.006 B:P11086:0.006
 HOH
 4.033
 CD1
 O
ILE B:133 B:133 56.0 0.32 H -81.8 -19.9 51.0 0.291 0.029 A:P11086:0.029
 HOH
 3.881
 CG2
 O
3kpv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 56.0 0.32 H -55.0 -44.8 56.0 0.32 0.0 HOH
 3.421
 O
 O
ILE B:133 B:133 60.0 0.343 H -82.1 -19.7 54.0 0.309 0.034 A:P11086:0.034
 HOH
 3.529
 O
 O
3kpw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 56.0 0.32 H -68.0 -46.1 56.0 0.32 0.0 HOH
 3.391
 O
 O
ILE B:133 B:133 55.0 0.314 H -88.1 -18.1 52.0 0.297 0.017 A:P11086:0.017
 HOH
 3.467
 CG2
 O
3kpy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 57.0 0.326 H -60.0 -43.4 56.0 0.32 0.006 B:P11086:0.006
 HOH
 3.378
 CD1
 O
ILE B:133 B:133 57.0 0.326 H -84.8 -17.4 51.0 0.291 0.035 A:P11086:0.034
 HOH
 3.444
 O
 O
3kqm 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 56.0 0.32 H -64.2 -44.0 56.0 0.32 0.0 HOH
 3.648
 CD1
 O
ILE B:133 B:133 60.0 0.343 H -93.1 -18.3 55.0 0.314 0.029 A:P11086:0.029
 HOH
 3.322
 O
 O
3kqo 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 56.0 0.32 H -60.4 -44.1 56.0 0.32 0.0 HOH
 3.701
 CD1
 O
ILE B:133 B:133 61.0 0.349 H -82.0 -18.8 56.0 0.32 0.029 A:P11086:0.029
 HOH
 3.314
 CG2
 O
3kqp 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 55.0 0.314 H -55.0 -48.4 54.0 0.309 0.005 B:P11086:0.006
 HOH
 5.102
 N
 O
ILE B:133 B:133 59.0 0.337 H -85.3 -24.6 54.0 0.309 0.028 A:P11086:0.029
 HOH
 4.302
 CD1
 O
3kqq 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 58.0 0.331 H -64.4 -48.9 58.0 0.331 0.0 HOH
 4.126
 CG1
 O
ILE B:133 B:133 58.0 0.331 H -92.3 -16.7 53.0 0.303 0.028 A:P11086:0.029
 HOH
 3.250
 O
 O
3kqs 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 56.0 0.32 H -63.8 -40.7 56.0 0.32 0.0 HOH
 3.242
 CD1
 O
ILE B:133 B:133 54.0 0.309 H -80.7 -23.0 50.0 0.286 0.023 A:P11086:0.023
 HOH
 3.574
 CG2
 O
3kqt 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 47.0 0.269 H -59.4 -43.3 47.0 0.269 0.0 HOH
 3.742
 O
 O
ILE B:133 B:133 54.0 0.309 H -83.2 -21.1 48.0 0.274 0.035 A:P11086:0.034
 HOH
 4.061
 CA
 O
3kqv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 56.0 0.32 H -67.0 -43.8 56.0 0.32 0.0 HOH
 3.766
 CD1
 O
ILE B:133 B:133 57.0 0.326 H -86.3 -22.4 54.0 0.309 0.017 A:P11086:0.017
 HOH
 3.443
 O
 O
3kqw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 57.0 0.326 H -62.8 -47.9 57.0 0.326 0.0 HOH
 3.564
 CD1
 O
ILE B:133 B:133 62.0 0.354 H -85.5 -19.4 59.0 0.337 0.017 A:P11086:0.017
 HOH
 4.696
 CD1
 O
3kqy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 53.0 0.303 H -67.0 -45.9 53.0 0.303 0.0 HOH
 3.560
 CD1
 O
ILE B:133 B:133 56.0 0.32 H -83.3 -24.3 51.0 0.291 0.029 A:P11086:0.029
 HOH
 3.593
 CG2
 O
3kr0 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 55.0 0.314 H -61.6 -46.2 55.0 0.314 0.0 HOH
 3.883
 CG2
 O
ILE B:133 B:133 57.0 0.326 H -88.1 -23.4 53.0 0.303 0.023 A:P11086:0.023
 HOH
 5.518
 N
 O
3kr1 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 54.0 0.309 H -63.8 -44.9 54.0 0.309 0.0 HOH
 3.870
 CD1
 O
ILE B:133 B:133 56.0 0.32 H -77.8 -26.3 49.0 0.28 0.04 A:P11086:0.04
 HOH
 4.548
 CD1
 O
3kr2 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ILE A:133 A:133 54.0 0.309 H -61.1 -52.1 54.0 0.309 0.0 HOH
 3.748
 CD1
 O
ILE B:133 B:133 57.0 0.326 H -85.7 -19.0 52.0 0.297 0.029 A:P11086:0.029
 HOH
 4.315
 CD1
 O
4dm3 1 P11086 100.0 0.0 X-RAY
 2012-04-25 ILE A:133 A:133 57.0 0.326 H -59.5 -41.5 57.0 0.326 0.0 HOH
 3.309
 CD1
 O
ILE B:133 B:133 56.0 0.32 H -89.1 -19.5 50.0 0.286 0.034 A:P11086:0.034
 HOH
 3.770
 CG2
 O
4mik 1 P11086 100.0 0.0 X-RAY
 2014-09-10 ILE A:133 A:133 53.0 0.303 H -67.9 -37.7 53.0 0.303 0.0 HOH
 2.895
 HD11
 O
ILE B:133 B:133 56.0 0.32 H -81.9 -21.2 52.0 0.297 0.023 A:P11086:0.023
 HOH
 3.378
 HD11
 O
4mq4 1 P11086 100.0 0.0 X-RAY
 2014-10-15 ILE A:133 A:133 63.0 0.36 H -77.4 -34.1 55.0 0.314 0.046 B:P11086:0.046
 HOH
 2.600
 HG23
 O
ILE B:133 B:133 55.0 0.314 H -66.1 -38.1 55.0 0.314 0.0 HOH
 2.909
 HD11
 O
3hca 1 P11086 99.65 0.0 X-RAY
 2009-08-25 ILE A:133 A:133 55.0 0.314 H -57.9 -47.2 55.0 0.314 0.0 EDO
HOH
 7.752
3.769
 CG2
O
 O1
O
ILE B:133 B:133 54.0 0.309 H -87.6 -20.8 NA NA NA
3hce 1 P11086 99.65 0.0 X-RAY
 2009-08-25 ILE A:133 A:133 55.0 0.314 H -73.8 -44.3 55.0 0.314 0.0 HOH
 3.304
 CD1
 O
ILE B:133 B:133 61.0 0.349 H -94.9 -18.0 NA NA NA
2obf 1 P11086 99.65 0.0 X-RAY
 2007-10-09 ILE A:133 A:133 49.0 0.28 H -65.1 -38.5 49.0 0.28 0.0 F83
HOH
 8.183
4.881
 CD1
O
 CL1
O
ILE B:133 B:633 56.0 0.32 H -79.5 -17.5 NA NA NA
2onz 1 P11086 99.65 0.0 X-RAY
 2007-10-09 ILE A:133 A:133 47.0 0.269 H -58.4 -42.4 47.0 0.269 0.0 TMJ
HOH
 8.332
6.160
 CD1
C
 CL1
O
ILE B:133 B:633 54.0 0.309 H -91.1 -14.7 NA NA NA
2opb 1 P11086 99.65 0.0 X-RAY
 2007-10-09 ILE A:133 A:133 56.0 0.32 H -62.9 -39.5 56.0 0.32 0.0 HOH
 3.480
 CD1
 O
ILE B:133 B:133 54.0 0.309 H -85.0 -12.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11086-f1 1 P11086 100.0 0.0 ILE A:133 A:133 54.0 0.309 H -74.8 -26.2