Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37826227 . G A CCDS11343.1:NM_002686.4:c.434cGc>cAc_NP_002677.1:p.145R>H Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1hnn 1 P11086 100.0 0.0 X-RAY
 2001-12-07 ARG A:145 A:145 57.0 NA H -70.1 -32.2 57.0 NA NA HOH
 6.339
 CB
 O
ARG B:145 B:645 139.0 0.618 H -68.7 -40.3 NA NA NA
1n7i 1 P11086 100.0 0.0 X-RAY
 2003-12-23 ARG A:145 A:145 54.0 NA H -73.5 -33.7 54.0 NA NA
ARG B:145 B:645 142.0 0.631 H -66.9 -39.0 NA NA NA
1n7j 1 P11086 100.0 0.0 X-RAY
 2003-12-23 ARG A:145 A:145 145.0 0.644 H -69.8 -39.3 145.0 0.644 0.0 HOH
 8.573
 N
 O
ARG B:145 B:645 144.0 0.64 H -69.9 -37.5 NA NA NA
6ws1 1 P11086 100.0 0.0 X-RAY
 2020-08-05 ARG A:157 A:145 143.0 0.636 H -71.8 -23.4 140.0 0.622 0.014 B:P11086:0.013
ARG B:157 B:145 156.0 0.693 H -81.9 -37.3 154.0 0.684 0.009 A:P11086:0.009
 HOH
 8.614
 N
 O
1yz3 1 P11086 100.0 0.0 X-RAY
 2006-02-07 ARG A:145 A:145 144.0 0.64 H -59.2 -46.1 144.0 0.64 0.0 HOH
 3.360
 NH1
 O
ARG B:145 B:145 149.0 0.662 H -64.7 -41.9 149.0 0.662 0.0 HOH
 2.775
 O
 O
2an3 1 P11086 100.0 0.0 X-RAY
 2006-03-14 ARG A:145 A:145 147.0 0.653 H -60.8 -47.2 147.0 0.653 0.0 HOH
 2.591
 NE
 O
ARG B:145 B:645 147.0 0.653 H -63.9 -38.0 NA NA NA
2an4 1 P11086 100.0 0.0 X-RAY
 2006-03-14 ARG A:145 A:145 144.0 0.64 H -66.6 -39.9 144.0 0.64 0.0 HOH
 2.592
 NE
 O
ARG B:145 B:145 147.0 0.653 H -65.5 -34.1 NA NA NA
2an5 1 P11086 100.0 0.0 X-RAY
 2006-03-14 ARG A:145 A:145 146.0 0.649 H -67.7 -40.7 146.0 0.649 0.0 HOH
 3.267
 CA
 O
ARG B:145 B:145 140.0 0.622 H -67.6 -37.2 NA NA NA
2g70 1 P11086 100.0 0.0 X-RAY
 2007-02-13 ARG A:145 A:145 146.0 0.649 H -55.9 -52.8 146.0 0.649 0.0 HOH
 3.504
 N
 O
ARG B:145 B:145 145.0 0.644 H -63.8 -38.0 NA NA NA
2g71 1 P11086 100.0 0.0 X-RAY
 2007-02-13 ARG A:145 A:145 146.0 0.649 H -62.9 -46.8 146.0 0.649 0.0 HOH
 3.369
 NH1
 O
ARG B:145 B:145 145.0 0.644 H -65.6 -36.5 NA NA NA
2g72 1 P11086 100.0 0.0 X-RAY
 2007-02-13 ARG A:145 A:145 148.0 0.658 H -61.6 -50.4 148.0 0.658 0.0 HOH
 3.255
 NH1
 O
ARG B:145 B:145 147.0 0.653 H -62.6 -40.4 NA NA NA
2g8n 1 P11086 100.0 0.0 X-RAY
 2006-09-12 ARG A:145 A:145 144.0 0.64 H -66.1 -46.7 144.0 0.64 0.0 HOH
 3.086
 NH1
 O
ARG B:145 B:145 146.0 0.649 H -62.5 -40.6 NA NA NA
2ony 1 P11086 100.0 0.0 X-RAY
 2007-10-09 ARG A:145 A:145 148.0 0.658 H -60.6 -41.4 148.0 0.658 0.0 HOH
 3.056
 NH1
 O
ARG B:145 B:645 144.0 0.64 H -65.6 -34.4 NA NA NA
3hcb 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ARG A:145 A:145 146.0 0.649 H -68.1 -41.9 146.0 0.649 0.0
ARG B:145 B:145 150.0 0.667 H -73.5 -35.0 NA NA NA
3hcc 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ARG A:145 A:145 149.0 0.662 H -69.8 -38.8 149.0 0.662 0.0 HOH
 2.683
 NH1
 O
ARG B:145 B:145 144.0 0.64 H -69.1 -38.3 NA NA NA
3hcd 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ARG A:145 A:145 148.0 0.658 H -54.8 -43.5 148.0 0.658 0.0 HOH
 2.616
 NE
 O
ARG B:145 B:145 147.0 0.653 H -68.1 -40.2 NA NA NA
3hcf 1 P11086 100.0 0.0 X-RAY
 2009-08-25 ARG A:145 A:145 145.0 0.644 H -54.4 -41.1 145.0 0.644 0.0 HOH
 3.368
 NH2
 O
ARG B:145 B:145 146.0 0.649 H -90.4 -29.7 NA NA NA
3kpj 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 150.0 0.667 H -57.2 -47.5 145.0 0.644 0.023 B:P11086:0.022
 HOH
 2.713
 NE
 O
ARG B:145 B:145 148.0 0.658 H -71.8 -37.2 146.0 0.649 0.009 A:P11086:0.009
 HOH
 3.329
 NH1
 O
3kpu 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 148.0 0.658 H -61.2 -48.3 143.0 0.636 0.022 B:P11086:0.022
 HOH
 2.621
 NE
 O
ARG B:145 B:145 145.0 0.644 H -65.2 -37.9 145.0 0.644 0.0 HOH
 2.888
 O
 O
3kpv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 149.0 0.662 H -53.9 -52.7 141.0 0.627 0.035 B:P11086:0.036
 HOH
 2.835
 NE
 O
ARG B:145 B:145 146.0 0.649 H -61.1 -41.5 144.0 0.64 0.009 A:P11086:0.009
 HOH
 2.441
 NH1
 O
3kpw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 146.0 0.649 H -56.1 -44.5 144.0 0.64 0.009 B:P11086:0.009
 HOH
 2.876
 O
 O
ARG B:145 B:145 146.0 0.649 H -72.5 -34.5 145.0 0.644 0.005 A:P11086:0.004
 HOH
 2.676
 O
 O
3kpy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 150.0 0.667 H -57.4 -47.7 147.0 0.653 0.014 B:P11086:0.013
 HOH
 2.816
 O
 O
ARG B:145 B:145 148.0 0.658 H -63.9 -40.9 146.0 0.649 0.009 A:P11086:0.009
 HOH
 2.518
 NH1
 O
3kqm 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 148.0 0.658 H -54.4 -49.1 143.0 0.636 0.022 B:P11086:0.022
 HOH
 5.710
 NH2
 O
ARG B:145 B:145 144.0 0.64 H -63.0 -36.0 143.0 0.636 0.004 A:P11086:0.004
 HOH
 2.690
 O
 O
3kqo 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 156.0 0.693 H -57.7 -45.5 150.0 0.667 0.026 B:P11086:0.027
 HOH
 2.664
 NE
 O
ARG B:145 B:145 146.0 0.649 H -58.8 -40.3 146.0 0.649 0.0 HOH
 2.658
 O
 O
3kqp 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 152.0 0.676 H -57.3 -48.1 146.0 0.649 0.027 B:P11086:0.027
 HOH
 3.478
 CA
 O
ARG B:145 B:145 148.0 0.658 H -61.1 -36.2 147.0 0.653 0.005 A:P11086:0.004
 HOH
 2.525
 NH1
 O
3kqq 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 147.0 0.653 H -54.1 -51.4 143.0 0.636 0.017 B:P11086:0.018
 HOH
 2.588
 NE
 O
ARG B:145 B:145 146.0 0.649 H -68.3 -36.0 144.0 0.64 0.009 A:P11086:0.009
 HOH
 2.745
 O
 O
3kqs 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 151.0 0.671 H -59.6 -45.3 147.0 0.653 0.018 B:P11086:0.018
 HOH
 2.752
 O
 O
ARG B:145 B:145 145.0 0.644 H -62.7 -42.1 145.0 0.644 0.0 HOH
 2.697
 NH1
 O
3kqt 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 147.0 0.653 H -53.7 -49.1 144.0 0.64 0.013 B:P11086:0.013
 HOH
 2.973
 O
 O
ARG B:145 B:145 147.0 0.653 H -64.0 -40.6 146.0 0.649 0.004 A:P11086:0.004
 HOH
 2.751
 O
 O
3kqv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 147.0 0.653 H -59.5 -48.7 143.0 0.636 0.017 B:P11086:0.018
 HOH
 2.690
 NE
 O
ARG B:145 B:145 147.0 0.653 H -64.6 -41.1 146.0 0.649 0.004 A:P11086:0.004
 HOH
 2.633
 NH1
 O
3kqw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 149.0 0.662 H -58.0 -48.6 146.0 0.649 0.013 B:P11086:0.013
 HOH
 2.707
 CD
 O
ARG B:145 B:145 149.0 0.662 H -60.9 -35.1 147.0 0.653 0.009 A:P11086:0.009
 HOH
 2.767
 O
 O
3kqy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 147.0 0.653 H -65.3 -42.8 143.0 0.636 0.017 B:P11086:0.018
 HOH
 3.408
 CA
 O
ARG B:145 B:145 146.0 0.649 H -64.6 -41.5 145.0 0.644 0.005 A:P11086:0.004
 HOH
 3.259
 NH2
 O
3kr0 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 148.0 0.658 H -62.2 -41.5 145.0 0.644 0.014 B:P11086:0.013
 HOH
 3.230
 CA
 O
ARG B:145 B:145 149.0 0.662 H -68.4 -29.5 147.0 0.653 0.009 A:P11086:0.009
 HOH
 2.679
 NH1
 O
3kr1 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 154.0 0.684 H -56.8 -49.0 148.0 0.658 0.026 B:P11086:0.027
 HOH
 3.390
 CA
 O
ARG B:145 B:145 149.0 0.662 H -61.9 -41.5 148.0 0.658 0.004 A:P11086:0.004
 HOH
 2.797
 NH2
 O
3kr2 1 P11086 100.0 0.0 X-RAY
 2010-09-29 ARG A:145 A:145 147.0 0.653 H -62.3 -47.6 143.0 0.636 0.017 B:P11086:0.018
 HOH
 5.467
 NH2
 O
ARG B:145 B:145 146.0 0.649 H -71.5 -34.9 146.0 0.649 0.0 HOH
 3.716
 CB
 O
4dm3 1 P11086 100.0 0.0 X-RAY
 2012-04-25 ARG A:145 A:145 149.0 0.662 H -61.3 -40.5 147.0 0.653 0.009 B:P11086:0.009
 HOH
 2.467
 NE
 O
ARG B:145 B:145 152.0 0.676 H -63.4 -42.3 150.0 0.667 0.009 A:P11086:0.009
 HOH
 2.492
 NH1
 O
4mik 1 P11086 100.0 0.0 X-RAY
 2014-09-10 ARG A:145 A:145 145.0 0.644 H -63.6 -47.7 142.0 0.631 0.013 B:P11086:0.013
 HOH
 2.567
 HA
 O
ARG B:145 B:145 149.0 0.662 H -62.3 -42.7 145.0 0.644 0.018 A:P11086:0.018
 HOH
 2.704
 HA
 O
4mq4 1 P11086 100.0 0.0 X-RAY
 2014-10-15 ARG A:145 A:145 140.0 0.622 H -68.2 -41.2 136.0 0.604 0.018 B:P11086:0.018
 HOH
 2.803
 O
 O
ARG B:145 B:145 150.0 0.667 H -56.2 -49.2 147.0 0.653 0.014 A:P11086:0.013
 HOH
 2.590
 HA
 O
3hca 1 P11086 99.65 0.0 X-RAY
 2009-08-25 ARG A:145 A:145 148.0 0.658 H -58.6 -46.7 148.0 0.658 0.0 HOH
 2.745
 NE
 O
ARG B:145 B:145 146.0 0.649 H -69.2 -36.5 NA NA NA
3hce 1 P11086 99.65 0.0 X-RAY
 2009-08-25 ARG A:145 A:145 147.0 0.653 H -71.2 -43.4 147.0 0.653 0.0 HOH
 3.231
 NH2
 O
ARG B:145 B:145 147.0 0.653 H -82.6 -27.4 NA NA NA
2obf 1 P11086 99.65 0.0 X-RAY
 2007-10-09 ARG A:145 A:145 147.0 0.653 H -63.8 -45.0 147.0 0.653 0.0 HOH
 2.678
 NH1
 O
ARG B:145 B:645 143.0 0.636 H -66.4 -36.7 NA NA NA
2onz 1 P11086 99.65 0.0 X-RAY
 2007-10-09 ARG A:145 A:145 146.0 0.649 H -57.7 -46.4 146.0 0.649 0.0 HOH
 3.882
 CA
 O
ARG B:145 B:645 149.0 0.662 H -71.4 -33.5 NA NA NA
2opb 1 P11086 99.65 0.0 X-RAY
 2007-10-09 ARG A:145 A:145 143.0 0.636 H -78.5 -53.8 143.0 0.636 0.0 HOH
 3.961
 N
 O
ARG B:145 B:145 146.0 0.649 H -67.0 -38.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11086-f1 1 P11086 100.0 0.0 ARG A:145 A:145 158.0 0.702 H -58.8 -44.5