Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr17 | 37826314 | . | C | A | CCDS11343.1:NM_002686.4:c.521cCt>cAt_NP_002677.1:p.174P>H | Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1hnn | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2001-12-07 | PRO | A:174 | A:174 | 68.0 | 0.469 | S | -89.3 | 129.2 | 68.0 | 0.469 | 0.0 |
HOH |
7.440 |
C |
O |
||
PRO | B:174 | B:674 | 70.0 | 0.483 | S | -88.7 | 153.9 | NA | NA | NA | |||||||||||||
1n7i | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | PRO | A:174 | A:174 | 74.0 | 0.51 | S | -78.8 | 141.4 | 74.0 | 0.51 | 0.0 | ||||||
PRO | B:174 | B:674 | 69.0 | 0.476 | S | -83.4 | 160.5 | NA | NA | NA | |||||||||||||
1n7j | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | PRO | A:174 | A:174 | 68.0 | 0.469 | S | -84.5 | 143.6 | 68.0 | 0.469 | 0.0 | ||||||
PRO | B:174 | B:674 | 71.0 | 0.49 | S | -86.4 | 154.2 | NA | NA | NA | |||||||||||||
6ws1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2020-08-05 | PRO | A:186 | A:174 | 83.0 | 0.572 | S | -80.8 | 136.4 | 83.0 | 0.572 | 0.0 | ||||||
PRO | B:186 | B:174 | 81.0 | 0.559 | S | -66.8 | 166.5 | 81.0 | 0.559 | 0.0 | |||||||||||||
1yz3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-02-07 | PRO | A:174 | A:174 | 80.0 | 0.552 | S | -80.5 | 148.5 | 80.0 | 0.552 | 0.0 |
HOH |
9.936 |
N |
O |
||
PRO | B:174 | B:174 | 70.0 | 0.483 | S | -83.9 | 155.9 | 70.0 | 0.483 | 0.0 |
HOH |
4.882 |
O |
O |
|||||||||
2an3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | PRO | A:174 | A:174 | 67.0 | 0.462 | S | -77.1 | 149.0 | 67.0 | 0.462 | 0.0 |
HOH |
7.974 |
O |
O |
||
PRO | B:174 | B:674 | 74.0 | 0.51 | S | -81.6 | 147.1 | NA | NA | NA | |||||||||||||
2an4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | PRO | A:174 | A:174 | 72.0 | 0.497 | S | -80.8 | 152.7 | 72.0 | 0.497 | 0.0 |
HOH |
5.043 |
C |
O |
||
PRO | B:174 | B:174 | 73.0 | 0.503 | S | -84.3 | 144.8 | NA | NA | NA | |||||||||||||
2an5 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | PRO | A:174 | A:174 | 65.0 | 0.448 | S | -81.4 | 160.3 | 65.0 | 0.448 | 0.0 |
HOH |
4.445 |
O |
O |
||
PRO | B:174 | B:174 | 73.0 | 0.503 | S | -82.4 | 150.6 | NA | NA | NA | |||||||||||||
2g70 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | PRO | A:174 | A:174 | 79.0 | 0.545 | S | -72.7 | -178.3 | 79.0 | 0.545 | 0.0 | ||||||
PRO | B:174 | B:174 | 71.0 | 0.49 | S | -80.3 | 152.7 | NA | NA | NA | |||||||||||||
2g71 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | PRO | A:174 | A:174 | 73.0 | 0.503 | S | -76.8 | 158.6 | 73.0 | 0.503 | 0.0 |
HOH |
2.700 |
O |
O |
||
PRO | B:174 | B:174 | 74.0 | 0.51 | S | -85.6 | 148.3 | NA | NA | NA | |||||||||||||
2g72 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | PRO | A:174 | A:174 | 75.0 | 0.517 | S | -80.9 | 162.0 | 75.0 | 0.517 | 0.0 |
HOH |
4.878 |
N |
O |
||
PRO | B:174 | B:174 | 80.0 | 0.552 | S | -80.2 | 143.5 | NA | NA | NA | |||||||||||||
2g8n | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-09-12 | PRO | A:174 | A:174 | 72.0 | 0.497 | S | -82.0 | 146.1 | 72.0 | 0.497 | 0.0 |
HOH |
2.893 |
O |
O |
||
PRO | B:174 | B:174 | 70.0 | 0.483 | S | -84.7 | 154.2 | NA | NA | NA | |||||||||||||
2ony | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-10-09 | PRO | A:174 | A:174 | 72.0 | 0.497 | S | -84.0 | 154.8 | 72.0 | 0.497 | 0.0 |
HOH |
4.028 |
O |
O |
||
PRO | B:174 | B:674 | 71.0 | 0.49 | S | -86.3 | 152.8 | NA | NA | NA | |||||||||||||
3hcb | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | PRO | A:174 | A:174 | 73.0 | 0.503 | S | -80.0 | 161.1 | 73.0 | 0.503 | 0.0 | ||||||
PRO | B:174 | B:174 | 75.0 | 0.517 | S | -77.2 | 146.8 | NA | NA | NA | |||||||||||||
3hcc | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | PRO | A:174 | A:174 | 67.0 | 0.462 | S | -82.2 | 145.2 | 67.0 | 0.462 | 0.0 |
HOH |
5.061 |
CB |
O |
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PRO | B:174 | B:174 | 77.0 | 0.531 | S | -79.7 | 146.9 | NA | NA | NA | |||||||||||||
3hcd | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | PRO | A:174 | A:174 | 69.0 | 0.476 | S | -82.8 | 148.4 | 69.0 | 0.476 | 0.0 |
HOH |
7.111 |
N |
O |
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PRO | B:174 | B:174 | 72.0 | 0.497 | S | -84.1 | 144.8 | NA | NA | NA | |||||||||||||
3hcf | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | PRO | A:174 | A:174 | 69.0 | 0.476 | S | -89.4 | 144.7 | 69.0 | 0.476 | 0.0 |
HOH |
5.235 |
N |
O |
||
PRO | B:174 | B:174 | 70.0 | 0.483 | S | -79.4 | 145.4 | NA | NA | NA | |||||||||||||
3kpj | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 70.0 | 0.483 | S | -79.6 | 152.2 | 70.0 | 0.483 | 0.0 |
HOH |
9.079 |
CA |
O |
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PRO | B:174 | B:174 | 70.0 | 0.483 | S | -85.9 | 149.0 | 70.0 | 0.483 | 0.0 |
HOH |
5.977 |
CB |
O |
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3kpu | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 77.0 | 0.531 | S | -81.2 | 159.2 | 77.0 | 0.531 | 0.0 |
HOH |
8.880 |
CB |
O |
||
PRO | B:174 | B:174 | 73.0 | 0.503 | S | -81.4 | 156.3 | 73.0 | 0.503 | 0.0 |
HOH |
2.720 |
O |
O |
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3kpv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 72.0 | 0.497 | S | -84.7 | 154.0 | 72.0 | 0.497 | 0.0 |
HOH |
5.397 |
C |
O |
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PRO | B:174 | B:174 | 73.0 | 0.503 | S | -80.3 | 149.2 | 73.0 | 0.503 | 0.0 |
HOH |
3.006 |
O |
O |
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3kpw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 73.0 | 0.503 | S | -84.7 | 164.3 | 73.0 | 0.503 | 0.0 |
HOH |
4.689 |
CB |
O |
||
PRO | B:174 | B:174 | 75.0 | 0.517 | S | -87.1 | 150.5 | 75.0 | 0.517 | 0.0 |
HOH |
2.888 |
O |
O |
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3kpy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 72.0 | 0.497 | S | -80.4 | 157.1 | 72.0 | 0.497 | 0.0 |
HOH |
2.793 |
O |
O |
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PRO | B:174 | B:174 | 73.0 | 0.503 | S | -83.1 | 156.5 | 73.0 | 0.503 | 0.0 |
HOH |
2.882 |
O |
O |
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3kqm | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 70.0 | 0.483 | S | -87.6 | 152.4 | 70.0 | 0.483 | 0.0 | ||||||
PRO | B:174 | B:174 | 70.0 | 0.483 | S | -85.7 | 152.6 | 70.0 | 0.483 | 0.0 |
HOH |
2.927 |
O |
O |
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3kqo | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 74.0 | 0.51 | S | -82.3 | 154.8 | 74.0 | 0.51 | 0.0 |
HOH |
3.394 |
O |
O |
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PRO | B:174 | B:174 | 72.0 | 0.497 | S | -84.8 | 156.4 | 72.0 | 0.497 | 0.0 |
HOH |
2.915 |
O |
O |
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3kqp | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 75.0 | 0.517 | S | -82.4 | 156.5 | 75.0 | 0.517 | 0.0 |
HOH |
4.746 |
C |
O |
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PRO | B:174 | B:174 | 71.0 | 0.49 | S | -89.9 | 155.9 | 71.0 | 0.49 | 0.0 |
HOH |
2.935 |
O |
O |
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3kqq | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 74.0 | 0.51 | S | -83.4 | 155.7 | 74.0 | 0.51 | 0.0 |
HOH |
3.850 |
CD |
O |
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PRO | B:174 | B:174 | 75.0 | 0.517 | S | -81.6 | 149.0 | 75.0 | 0.517 | 0.0 |
HOH |
2.617 |
O |
O |
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3kqs | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 77.0 | 0.531 | S | -78.8 | 159.1 | 77.0 | 0.531 | 0.0 |
HOH |
3.685 |
O |
O |
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PRO | B:174 | B:174 | 76.0 | 0.524 | S | -84.4 | 156.0 | 76.0 | 0.524 | 0.0 |
HOH |
2.788 |
O |
O |
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3kqt | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 74.0 | 0.51 | S | -84.4 | 152.5 | 74.0 | 0.51 | 0.0 |
HOH |
3.240 |
O |
O |
||
PRO | B:174 | B:174 | 74.0 | 0.51 | S | -87.2 | 156.4 | 74.0 | 0.51 | 0.0 |
HOH |
2.687 |
O |
O |
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3kqv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 69.0 | 0.476 | S | -80.4 | 161.7 | 69.0 | 0.476 | 0.0 |
HOH |
5.167 |
C |
O |
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PRO | B:174 | B:174 | 73.0 | 0.503 | S | -83.1 | 158.6 | 73.0 | 0.503 | 0.0 |
HOH |
2.936 |
O |
O |
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3kqw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 77.0 | 0.531 | S | -82.1 | 151.6 | 77.0 | 0.531 | 0.0 |
HOH |
8.850 |
CA |
O |
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PRO | B:174 | B:174 | 69.0 | 0.476 | S | -90.6 | 151.6 | 69.0 | 0.476 | 0.0 |
HOH |
4.572 |
O |
O |
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3kqy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 71.0 | 0.49 | S | -78.8 | 156.4 | 71.0 | 0.49 | 0.0 |
HOH |
3.773 |
O |
O |
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PRO | B:174 | B:174 | 74.0 | 0.51 | S | -82.3 | 155.1 | 74.0 | 0.51 | 0.0 |
HOH |
2.976 |
O |
O |
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3kr0 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 72.0 | 0.497 | S | -82.1 | 154.2 | 72.0 | 0.497 | 0.0 |
HOH |
4.596 |
CB |
O |
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PRO | B:174 | B:174 | 73.0 | 0.503 | S | -82.3 | 152.5 | 73.0 | 0.503 | 0.0 |
HOH |
7.905 |
C |
O |
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3kr1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 72.0 | 0.497 | S | -83.1 | 151.9 | 72.0 | 0.497 | 0.0 |
HOH |
7.892 |
C |
O |
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PRO | B:174 | B:174 | 71.0 | 0.49 | S | -82.3 | 152.1 | 71.0 | 0.49 | 0.0 |
HOH |
3.068 |
O |
O |
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3kr2 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | PRO | A:174 | A:174 | 73.0 | 0.503 | S | -82.1 | 155.0 | 73.0 | 0.503 | 0.0 |
HOH |
4.936 |
CB |
O |
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PRO | B:174 | B:174 | 73.0 | 0.503 | S | -79.7 | 152.7 | 73.0 | 0.503 | 0.0 |
HOH |
3.050 |
O |
O |
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4dm3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2012-04-25 | PRO | A:174 | A:174 | 71.0 | 0.49 | S | -79.6 | 152.9 | 71.0 | 0.49 | 0.0 |
HOH |
4.843 |
CB |
O |
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PRO | B:174 | B:174 | 73.0 | 0.503 | S | -82.4 | 153.3 | 73.0 | 0.503 | 0.0 |
HOH |
2.944 |
O |
O |
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4mik | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-09-10 | PRO | A:174 | A:174 | 74.0 | 0.51 | S | -76.4 | 158.4 | 74.0 | 0.51 | 0.0 |
HOH |
5.106 |
O |
O |
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PRO | B:174 | B:174 | 76.0 | 0.524 | S | -75.2 | 154.8 | 76.0 | 0.524 | 0.0 |
HOH |
2.840 |
O |
O |
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4mq4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-10-15 | PRO | A:174 | A:174 | 77.0 | 0.531 | S | -75.7 | 159.4 | 77.0 | 0.531 | 0.0 |
HOH |
2.599 |
O |
O |
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PRO | B:174 | B:174 | 76.0 | 0.524 | S | -72.7 | 170.3 | 76.0 | 0.524 | 0.0 |
HOH |
7.504 |
O |
O |
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3hca | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | PRO | A:174 | A:174 | 72.0 | 0.497 | S | -81.0 | 155.5 | 72.0 | 0.497 | 0.0 |
HOH |
2.698 |
O |
O |
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PRO | B:174 | B:174 | 73.0 | 0.503 | S | -80.0 | 156.3 | NA | NA | NA | |||||||||||||
3hce | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | PRO | A:174 | A:174 | 70.0 | 0.483 | S | -83.9 | 149.6 | 70.0 | 0.483 | 0.0 |
HOH |
4.964 |
N |
O |
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PRO | B:174 | B:174 | 71.0 | 0.49 | S | -86.6 | 144.2 | NA | NA | NA | |||||||||||||
2obf | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | PRO | A:174 | A:174 | 68.0 | 0.469 | S | -79.7 | 145.7 | 68.0 | 0.469 | 0.0 |
HOH |
2.856 |
O |
O |
||
PRO | B:174 | B:674 | 72.0 | 0.497 | S | -79.9 | 157.5 | NA | NA | NA | |||||||||||||
2onz | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | PRO | A:174 | A:174 | 69.0 | 0.476 | S | -88.2 | 145.7 | 69.0 | 0.476 | 0.0 |
HOH |
4.097 |
O |
O |
||
PRO | B:174 | B:674 | 68.0 | 0.469 | S | -88.0 | 152.1 | NA | NA | NA | |||||||||||||
2opb | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | PRO | A:174 | A:174 | 69.0 | 0.476 | S | -79.3 | 153.9 | 69.0 | 0.476 | 0.0 |
HOH |
3.572 |
CG |
O |
||
PRO | B:174 | B:174 | 73.0 | 0.503 | S | -87.0 | 160.4 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p11086-f1 | 1 | P11086 | 100.0 | 0.0 | PRO | A:174 | A:174 | 75.0 | 0.517 | S | -72.8 | 146.7 |