Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr17 | 37826316 | . | G | A | CCDS11343.1:NM_002686.4:c.523Gct>Act_NP_002677.1:p.175A>T | Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1hnn | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2001-12-07 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -50.6 | 152.4 | 0.0 | 0.0 | 0.0 |
HOH |
4.891 |
CB |
O |
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| ALA | B:175 | B:675 | 0.0 | 0.0 | E | -70.3 | 148.5 | NA | NA | NA | |||||||||||||
| 1n7i | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -66.1 | 151.9 | 0.0 | 0.0 | 0.0 | ||||||
| ALA | B:175 | B:675 | 0.0 | 0.0 | E | -81.4 | 155.5 | NA | NA | NA | |||||||||||||
| 1n7j | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -62.6 | 157.4 | 0.0 | 0.0 | 0.0 | ||||||
| ALA | B:175 | B:675 | 0.0 | 0.0 | E | -76.8 | 160.3 | NA | NA | NA | |||||||||||||
| 6ws1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2020-08-05 | ALA | A:187 | A:175 | 2.0 | 0.017 | E | -64.3 | 161.3 | 2.0 | 0.017 | 0.0 | ||||||
| ALA | B:187 | B:175 | 0.0 | 0.0 | E | -97.5 | 157.8 | 0.0 | 0.0 | 0.0 | |||||||||||||
| 1yz3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-02-07 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -83.8 | 167.6 | 0.0 | 0.0 | 0.0 | ||||||
| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -75.4 | 150.6 | 0.0 | 0.0 | 0.0 |
HOH |
5.420 |
CB |
O |
|||||||||
| 2an3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -72.4 | 156.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.700 |
CB |
O |
||
| ALA | B:175 | B:675 | 0.0 | 0.0 | E | -77.6 | 158.1 | NA | NA | NA | |||||||||||||
| 2an4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -76.1 | 152.4 | 0.0 | 0.0 | 0.0 |
HOH |
3.295 |
CB |
O |
||
| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -72.2 | 154.3 | NA | NA | NA | |||||||||||||
| 2an5 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -80.3 | 159.6 | 0.0 | 0.0 | 0.0 |
HOH |
5.423 |
CB |
O |
||
| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -80.8 | 159.2 | NA | NA | NA | |||||||||||||
| 2g70 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -107.0 | 157.2 | 0.0 | 0.0 | 0.0 | ||||||
| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -72.2 | 157.0 | NA | NA | NA | |||||||||||||
| 2g71 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -82.3 | 150.6 | 0.0 | 0.0 | 0.0 |
HOH |
4.119 |
CA |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -75.4 | 159.0 | NA | NA | NA | |||||||||||||
| 2g72 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -86.4 | 152.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.664 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -73.3 | 153.4 | NA | NA | NA | |||||||||||||
| 2g8n | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-09-12 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -70.5 | 157.3 | 0.0 | 0.0 | 0.0 |
HOH |
3.997 |
CA |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -74.1 | 153.0 | NA | NA | NA | |||||||||||||
| 2ony | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-10-09 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -74.2 | 162.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.465 |
O |
O |
||
| ALA | B:175 | B:675 | 0.0 | 0.0 | E | -76.6 | 158.3 | NA | NA | NA | |||||||||||||
| 3hcb | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -80.5 | 149.5 | 0.0 | 0.0 | 0.0 | ||||||
| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -73.1 | 154.6 | NA | NA | NA | |||||||||||||
| 3hcc | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -66.5 | 146.8 | 0.0 | 0.0 | 0.0 |
HOH |
5.575 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -75.2 | 155.5 | NA | NA | NA | |||||||||||||
| 3hcd | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -67.5 | 156.1 | 0.0 | 0.0 | 0.0 |
HOH |
5.520 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -70.7 | 159.9 | NA | NA | NA | |||||||||||||
| 3hcf | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -57.9 | 146.6 | 0.0 | 0.0 | 0.0 |
HOH |
7.818 |
N |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -73.5 | 154.3 | NA | NA | NA | |||||||||||||
| 3kpj | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -72.3 | 157.4 | 0.0 | 0.0 | 0.0 |
HOH |
9.683 |
N |
O |
||
| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -74.1 | 158.0 | 0.0 | 0.0 | 0.0 |
HOH |
8.459 |
O |
O |
|||||||||
| 3kpu | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -74.8 | 141.0 | 0.0 | 0.0 | 0.0 | ||||||
| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -78.6 | 159.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.189 |
CB |
O |
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| 3kpv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -72.3 | 145.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.606 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -71.0 | 154.8 | 0.0 | 0.0 | 0.0 |
HOH |
4.035 |
CA |
O |
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| 3kpw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -79.1 | 148.8 | 0.0 | 0.0 | 0.0 |
HOH |
3.355 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -69.9 | 156.7 | 0.0 | 0.0 | 0.0 |
HOH |
2.909 |
CB |
O |
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| 3kpy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -71.7 | 149.3 | 0.0 | 0.0 | 0.0 |
HOH |
3.485 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -77.8 | 159.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.398 |
CB |
O |
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| 3kqm | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -67.6 | 149.9 | 0.0 | 0.0 | 0.0 | ||||||
| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -71.2 | 158.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.885 |
O |
O |
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| 3kqo | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -72.6 | 150.9 | 0.0 | 0.0 | 0.0 |
HOH |
3.300 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -79.2 | 152.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.316 |
CB |
O |
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| 3kqp | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -76.6 | 149.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.384 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -73.7 | 165.1 | 0.0 | 0.0 | 0.0 |
HOH |
3.013 |
CB |
O |
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| 3kqq | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -70.9 | 149.1 | 0.0 | 0.0 | 0.0 |
HOH |
3.524 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -70.0 | 162.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.525 |
O |
O |
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| 3kqs | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -79.1 | 156.0 | 0.0 | 0.0 | 0.0 |
HOH |
3.556 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -79.7 | 155.2 | 0.0 | 0.0 | 0.0 |
HOH |
3.479 |
CB |
O |
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| 3kqt | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -70.2 | 155.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.518 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -76.2 | 156.6 | 0.0 | 0.0 | 0.0 |
HOH |
3.480 |
CB |
O |
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| 3kqv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -81.4 | 150.4 | 0.0 | 0.0 | 0.0 |
HOH |
3.345 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -80.5 | 160.4 | 0.0 | 0.0 | 0.0 |
HOH |
3.333 |
CB |
O |
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| 3kqw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -72.2 | 156.5 | 0.0 | 0.0 | 0.0 |
HOH |
9.378 |
O |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -71.3 | 152.1 | 0.0 | 0.0 | 0.0 |
HOH |
4.162 |
CB |
O |
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| 3kqy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -73.8 | 151.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.670 |
O |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -80.4 | 148.5 | 0.0 | 0.0 | 0.0 |
HOH |
4.259 |
CA |
O |
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| 3kr0 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -74.4 | 151.5 | 0.0 | 0.0 | 0.0 |
HOH |
7.274 |
N |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -76.4 | 151.7 | 0.0 | 0.0 | 0.0 |
HOH |
5.624 |
CB |
O |
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| 3kr1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -73.7 | 154.9 | 0.0 | 0.0 | 0.0 |
HOH |
5.808 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -76.6 | 154.3 | 0.0 | 0.0 | 0.0 |
HOH |
4.392 |
C |
O |
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| 3kr2 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -74.1 | 149.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.543 |
CB |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -73.4 | 156.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.318 |
CA |
O |
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| 4dm3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2012-04-25 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -66.1 | 153.0 | 0.0 | 0.0 | 0.0 |
HOH |
7.416 |
N |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -73.5 | 160.8 | 0.0 | 0.0 | 0.0 |
HOH |
3.713 |
O |
O |
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| 4mik | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-09-10 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -80.6 | 156.5 | 0.0 | 0.0 | 0.0 |
HOH |
3.127 |
HB2 |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -81.7 | 155.9 | 0.0 | 0.0 | 0.0 |
HOH |
2.727 |
HB2 |
O |
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| 4mq4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-10-15 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -88.1 | 154.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.155 |
HA |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -92.5 | 153.2 | 0.0 | 0.0 | 0.0 |
HOH |
5.388 |
HB1 |
O |
|||||||||
| 3hca | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -75.6 | 148.7 | 0.0 | 0.0 | 0.0 |
HOH |
4.150 |
CA |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -82.0 | 158.9 | NA | NA | NA | |||||||||||||
| 3hce | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -65.8 | 152.5 | 0.0 | 0.0 | 0.0 |
HOH |
7.380 |
N |
O |
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| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -72.4 | 155.3 | NA | NA | NA | |||||||||||||
| 2obf | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -66.4 | 154.7 | 0.0 | 0.0 | 0.0 |
HOH |
3.971 |
CA |
O |
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| ALA | B:175 | B:675 | 0.0 | 0.0 | E | -79.3 | 157.2 | NA | NA | NA | |||||||||||||
| 2onz | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -64.3 | 162.2 | 0.0 | 0.0 | 0.0 |
HOH |
4.557 |
CB |
O |
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| ALA | B:175 | B:675 | 0.0 | 0.0 | E | -73.5 | 153.6 | NA | NA | NA | |||||||||||||
| 2opb | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -80.6 | 152.0 | 0.0 | 0.0 | 0.0 |
HOH |
5.153 |
O |
O |
||
| ALA | B:175 | B:175 | 0.0 | 0.0 | E | -87.1 | 159.1 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p11086-f1 | 1 | P11086 | 100.0 | 0.0 | ALA | A:175 | A:175 | 0.0 | 0.0 | E | -74.6 | 157.4 | |