Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr17 | 37826379 | . | C | A | CCDS11343.1:NM_002686.4:c.586Cgg>Agg_NP_002677.1:p.196R>R | Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1hnn | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2001-12-07 | ARG | A:196 | A:196 | 125.0 | 0.556 | H | -65.0 | -42.5 | 125.0 | 0.556 | 0.0 |
HOH |
3.533 |
NH1 |
O |
||
ARG | B:196 | B:696 | 76.0 | 0.338 | H | -57.0 | -44.2 | NA | NA | NA | |||||||||||||
1n7i | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | ARG | A:196 | A:196 | 119.0 | 0.529 | H | -53.3 | -41.6 | 119.0 | 0.529 | 0.0 |
HOH |
2.417 |
NH1 |
O |
||
ARG | B:196 | B:696 | 81.0 | 0.36 | H | -52.3 | -53.4 | NA | NA | NA | |||||||||||||
1n7j | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | ARG | A:196 | A:196 | 122.0 | 0.542 | H | -64.4 | -40.5 | 122.0 | 0.542 | 0.0 |
HOH |
2.751 |
NH1 |
O |
||
ARG | B:196 | B:696 | 81.0 | 0.36 | H | -54.8 | -49.0 | NA | NA | NA | |||||||||||||
6ws1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2020-08-05 | ARG | A:208 | A:196 | 119.0 | 0.529 | H | -72.5 | -52.8 | 119.0 | 0.529 | 0.0 | ||||||
ARG | B:208 | B:196 | 93.0 | 0.413 | H | -79.6 | -33.8 | 93.0 | 0.413 | 0.0 | |||||||||||||
1yz3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-02-07 | ARG | A:196 | A:196 | 99.0 | 0.44 | H | -67.6 | -44.9 | 99.0 | 0.44 | 0.0 |
HOH |
3.405 |
NH2 |
O |
||
ARG | B:196 | B:196 | 82.0 | 0.364 | H | -62.8 | -42.5 | 82.0 | 0.364 | 0.0 |
HOH |
2.911 |
NE |
O |
|||||||||
2an3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | ARG | A:196 | A:196 | 130.0 | 0.578 | H | -62.0 | -49.3 | 130.0 | 0.578 | 0.0 |
HOH |
2.767 |
NH2 |
O |
||
ARG | B:196 | B:696 | 89.0 | 0.396 | H | -61.9 | -46.6 | NA | NA | NA | |||||||||||||
2an4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | ARG | A:196 | A:196 | 129.0 | 0.573 | H | -62.8 | -40.1 | 129.0 | 0.573 | 0.0 |
HOH |
2.524 |
NH2 |
O |
||
ARG | B:196 | B:196 | 91.0 | 0.404 | H | -65.7 | -41.0 | NA | NA | NA | |||||||||||||
2an5 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | ARG | A:196 | A:196 | 125.0 | 0.556 | H | -65.8 | -39.8 | 125.0 | 0.556 | 0.0 |
HOH |
2.618 |
NH2 |
O |
||
ARG | B:196 | B:196 | 84.0 | 0.373 | H | -64.6 | -41.3 | NA | NA | NA | |||||||||||||
2g70 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | ARG | A:196 | A:196 | 114.0 | 0.507 | H | -75.0 | -48.5 | 114.0 | 0.507 | 0.0 |
HOH |
5.301 |
NH2 |
O |
||
ARG | B:196 | B:196 | 147.0 | 0.653 | H | -68.8 | -35.8 | NA | NA | NA | |||||||||||||
2g71 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | ARG | A:196 | A:196 | 123.0 | 0.547 | H | -59.2 | -43.9 | 123.0 | 0.547 | 0.0 |
HOH |
2.854 |
NH2 |
O |
||
ARG | B:196 | B:196 | 82.0 | 0.364 | H | -66.7 | -43.8 | NA | NA | NA | |||||||||||||
2g72 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | ARG | A:196 | A:196 | 112.0 | 0.498 | H | -62.0 | -47.8 | 112.0 | 0.498 | 0.0 |
HOH |
2.547 |
NE |
O |
||
ARG | B:196 | B:196 | 81.0 | 0.36 | H | -64.5 | -42.2 | NA | NA | NA | |||||||||||||
2g8n | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-09-12 | ARG | A:196 | A:196 | 127.0 | 0.564 | H | -66.9 | -45.6 | 127.0 | 0.564 | 0.0 |
HOH |
3.610 |
CD |
O |
||
ARG | B:196 | B:196 | 85.0 | 0.378 | H | -65.8 | -43.8 | NA | NA | NA | |||||||||||||
2ony | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-10-09 | ARG | A:196 | A:196 | 120.0 | 0.533 | H | -66.5 | -50.1 | 120.0 | 0.533 | 0.0 |
HOH |
2.846 |
NH2 |
O |
||
ARG | B:196 | B:696 | 92.0 | 0.409 | H | -64.6 | -40.0 | NA | NA | NA | |||||||||||||
3hcb | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:196 | A:196 | 126.0 | 0.56 | H | -67.4 | -44.7 | 126.0 | 0.56 | 0.0 | ||||||
ARG | B:196 | B:196 | 88.0 | 0.391 | H | -68.6 | -42.0 | NA | NA | NA | |||||||||||||
3hcc | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:196 | A:196 | 128.0 | 0.569 | H | -61.8 | -48.6 | 128.0 | 0.569 | 0.0 |
HOH |
3.009 |
NH2 |
O |
||
ARG | B:196 | B:196 | 93.0 | 0.413 | H | -64.8 | -44.4 | NA | NA | NA | |||||||||||||
3hcd | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:196 | A:196 | 128.0 | 0.569 | H | -74.1 | -38.8 | 128.0 | 0.569 | 0.0 |
HOH |
3.977 |
NH1 |
O |
||
ARG | B:196 | B:196 | 93.0 | 0.413 | H | -66.1 | -37.4 | NA | NA | NA | |||||||||||||
3hcf | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:196 | A:196 | 124.0 | 0.551 | H | -70.6 | -50.1 | 124.0 | 0.551 | 0.0 |
HOH |
6.204 |
CG |
O |
||
ARG | B:196 | B:196 | 90.0 | 0.4 | H | -70.5 | -51.0 | NA | NA | NA | |||||||||||||
3kpj | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 126.0 | 0.56 | H | -65.9 | -43.4 | 126.0 | 0.56 | 0.0 |
HOH |
2.902 |
NH2 |
O |
||
ARG | B:196 | B:196 | 90.0 | 0.4 | H | -63.0 | -44.4 | 90.0 | 0.4 | 0.0 |
HOH |
5.969 |
NH2 |
O |
|||||||||
3kpu | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 125.0 | 0.556 | H | -61.1 | -49.0 | 125.0 | 0.556 | 0.0 |
HOH |
2.972 |
NE |
O |
||
ARG | B:196 | B:196 | 78.0 | 0.347 | H | -58.2 | -42.1 | 78.0 | 0.347 | 0.0 |
SAH HOH |
9.993 3.187 |
O CD |
N1 O |
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3kpv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 127.0 | 0.564 | H | -65.0 | -46.7 | 127.0 | 0.564 | 0.0 |
HOH |
4.202 |
CB |
O |
||
ARG | B:196 | B:196 | 76.0 | 0.338 | H | -56.3 | -41.9 | 76.0 | 0.338 | 0.0 |
HOH |
3.174 |
NH2 |
O |
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3kpw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 119.0 | 0.529 | H | -60.0 | -47.0 | 119.0 | 0.529 | 0.0 |
HOH |
3.099 |
CD |
O |
||
ARG | B:196 | B:196 | 85.0 | 0.378 | H | -57.1 | -44.0 | 85.0 | 0.378 | 0.0 |
HOH |
3.319 |
NE |
O |
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3kpy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 130.0 | 0.578 | H | -64.7 | -43.4 | 130.0 | 0.578 | 0.0 |
HOH |
3.488 |
CG |
O |
||
ARG | B:196 | B:196 | 85.0 | 0.378 | H | -60.2 | -41.8 | 85.0 | 0.378 | 0.0 |
HOH |
2.938 |
NE |
O |
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3kqm | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 124.0 | 0.551 | H | -61.2 | -45.8 | 124.0 | 0.551 | 0.0 |
HOH |
6.974 |
NH1 |
O |
||
ARG | B:196 | B:196 | 81.0 | 0.36 | H | -60.6 | -41.7 | 81.0 | 0.36 | 0.0 |
HOH |
3.274 |
NH2 |
O |
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3kqo | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 124.0 | 0.551 | H | -68.5 | -48.0 | 124.0 | 0.551 | 0.0 |
HOH |
2.871 |
CD |
O |
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ARG | B:196 | B:196 | 71.0 | 0.316 | H | -65.2 | -39.7 | 71.0 | 0.316 | 0.0 |
HOH |
2.789 |
NH2 |
O |
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3kqp | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 128.0 | 0.569 | H | -68.3 | -45.6 | 128.0 | 0.569 | 0.0 |
HOH |
3.704 |
CB |
O |
||
ARG | B:196 | B:196 | 82.0 | 0.364 | H | -57.8 | -42.2 | 82.0 | 0.364 | 0.0 |
HOH |
3.596 |
CB |
O |
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3kqq | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 125.0 | 0.556 | H | -64.9 | -46.8 | 125.0 | 0.556 | 0.0 |
HOH |
3.472 |
CG |
O |
||
ARG | B:196 | B:196 | 87.0 | 0.387 | H | -54.4 | -48.4 | 87.0 | 0.387 | 0.0 |
HOH |
3.326 |
CB |
O |
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3kqs | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 127.0 | 0.564 | H | -63.7 | -44.5 | 127.0 | 0.564 | 0.0 |
HOH |
3.508 |
CG |
O |
||
ARG | B:196 | B:196 | 82.0 | 0.364 | H | -61.5 | -40.8 | 82.0 | 0.364 | 0.0 |
HOH |
2.757 |
NH2 |
O |
|||||||||
3kqt | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 126.0 | 0.56 | H | -67.5 | -47.4 | 126.0 | 0.56 | 0.0 |
HOH |
3.409 |
CG |
O |
||
ARG | B:196 | B:196 | 79.0 | 0.351 | H | -64.5 | -44.5 | 79.0 | 0.351 | 0.0 |
HOH |
2.892 |
NE |
O |
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3kqv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 127.0 | 0.564 | H | -65.9 | -39.5 | 127.0 | 0.564 | 0.0 |
HOH |
3.382 |
CG |
O |
||
ARG | B:196 | B:196 | 86.0 | 0.382 | H | -61.3 | -43.4 | 86.0 | 0.382 | 0.0 |
HOH |
2.796 |
NH1 |
O |
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3kqw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 123.0 | 0.547 | H | -72.8 | -47.6 | 123.0 | 0.547 | 0.0 |
HOH |
3.351 |
CG |
O |
||
ARG | B:196 | B:196 | 87.0 | 0.387 | H | -64.3 | -43.8 | 87.0 | 0.387 | 0.0 |
HOH |
3.388 |
NH2 |
O |
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3kqy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 125.0 | 0.556 | H | -68.4 | -46.9 | 125.0 | 0.556 | 0.0 |
HOH |
2.700 |
NH2 |
O |
||
ARG | B:196 | B:196 | 87.0 | 0.387 | H | -66.9 | -42.8 | 87.0 | 0.387 | 0.0 |
HOH |
3.118 |
NE |
O |
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3kr0 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 125.0 | 0.556 | H | -70.4 | -49.1 | 125.0 | 0.556 | 0.0 |
HOH |
2.784 |
NE |
O |
||
ARG | B:196 | B:196 | 85.0 | 0.378 | H | -66.1 | -45.8 | 85.0 | 0.378 | 0.0 |
HOH |
3.119 |
CD |
O |
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3kr1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 125.0 | 0.556 | H | -69.4 | -49.9 | 125.0 | 0.556 | 0.0 |
HOH |
6.894 |
O |
O |
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ARG | B:196 | B:196 | 88.0 | 0.391 | H | -64.6 | -42.4 | 88.0 | 0.391 | 0.0 |
HOH |
2.709 |
NH2 |
O |
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3kr2 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:196 | A:196 | 125.0 | 0.556 | H | -65.2 | -50.4 | 125.0 | 0.556 | 0.0 |
HOH |
3.076 |
CD |
O |
||
ARG | B:196 | B:196 | 86.0 | 0.382 | H | -59.0 | -51.2 | 86.0 | 0.382 | 0.0 |
HOH |
3.421 |
NH2 |
O |
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4dm3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2012-04-25 | ARG | A:196 | A:196 | 127.0 | 0.564 | H | -59.7 | -48.7 | 127.0 | 0.564 | 0.0 |
HOH |
2.500 |
NH1 |
O |
||
ARG | B:196 | B:196 | 86.0 | 0.382 | H | -58.0 | -40.1 | 86.0 | 0.382 | 0.0 |
HOH |
2.919 |
NE |
O |
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4mik | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-09-10 | ARG | A:196 | A:196 | 125.0 | 0.556 | H | -66.8 | -42.7 | 125.0 | 0.556 | 0.0 |
JIL HOH |
9.718 2.827 |
HH21 HG3 |
H322 O |
||
ARG | B:196 | B:196 | 85.0 | 0.378 | H | -63.7 | -38.8 | 85.0 | 0.378 | 0.0 |
JIL HOH |
9.859 2.101 |
HH21 HH11 |
H322 O |
|||||||||
4mq4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-10-15 | ARG | A:196 | A:196 | 113.0 | 0.502 | H | -63.5 | -39.2 | 113.0 | 0.502 | 0.0 |
2D5 HOH |
9.925 2.469 |
C HE |
H011 O |
||
ARG | B:196 | B:196 | 127.0 | 0.564 | H | -67.5 | -44.8 | 127.0 | 0.564 | 0.0 |
2D5 HOH |
8.854 6.810 |
HH21 O |
H012 O |
|||||||||
3hca | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:196 | A:196 | 121.0 | 0.538 | H | -64.1 | -45.7 | 121.0 | 0.538 | 0.0 |
HOH |
2.719 |
NH2 |
O |
||
ARG | B:196 | B:196 | 88.0 | 0.391 | H | -61.4 | -40.0 | NA | NA | NA | |||||||||||||
3hce | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:196 | A:196 | 124.0 | 0.551 | H | -75.0 | -47.2 | 124.0 | 0.551 | 0.0 |
HOH |
4.515 |
NH1 |
O |
||
ARG | B:196 | B:196 | 92.0 | 0.409 | H | -66.8 | -47.9 | NA | NA | NA | |||||||||||||
2obf | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | ARG | A:196 | A:196 | 126.0 | 0.56 | H | -62.7 | -49.6 | 126.0 | 0.56 | 0.0 |
HOH |
3.544 |
CD |
O |
||
ARG | B:196 | B:696 | 89.0 | 0.396 | H | -66.2 | -37.8 | NA | NA | NA | |||||||||||||
2onz | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | ARG | A:196 | A:196 | 121.0 | 0.538 | H | -61.8 | -54.2 | 121.0 | 0.538 | 0.0 |
HOH |
4.083 |
CB |
O |
||
ARG | B:196 | B:696 | 85.0 | 0.378 | H | -65.3 | -39.3 | NA | NA | NA | |||||||||||||
2opb | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | ARG | A:196 | A:196 | 112.0 | 0.498 | H | -60.2 | -50.3 | 112.0 | 0.498 | 0.0 |
SAH HOH |
9.433 2.563 |
NH2 NH2 |
N6 O |
||
ARG | B:196 | B:196 | 90.0 | 0.4 | H | -61.1 | -45.1 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p11086-f1 | 1 | P11086 | 100.0 | 0.0 | ARG | A:196 | A:196 | 67.0 | 0.298 | H | -62.2 | -41.7 |