Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr17 | 37826401 | . | C | A | CCDS11343.1:NM_002686.4:c.608aCg>aAg_NP_002677.1:p.203T>K | Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1hnn | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2001-12-07 | THR | A:203 | A:203 | 87.0 | 0.621 | T | -62.6 | -28.4 | 87.0 | 0.621 | 0.0 | ||||||
THR | B:203 | B:703 | 85.0 | 0.607 | T | -76.7 | -31.5 | NA | NA | NA | |||||||||||||
1n7i | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | THR | A:203 | A:203 | 89.0 | 0.636 | T | -68.6 | -22.4 | 89.0 | 0.636 | 0.0 | ||||||
THR | B:203 | B:703 | 89.0 | 0.636 | T | -72.7 | -27.4 | NA | NA | NA | |||||||||||||
1n7j | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | THR | A:203 | A:203 | 81.0 | 0.579 | T | -71.7 | -24.6 | 81.0 | 0.579 | 0.0 | ||||||
THR | B:203 | B:703 | 88.0 | 0.629 | T | -65.8 | -29.3 | NA | NA | NA | |||||||||||||
6ws1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2020-08-05 | THR | A:215 | A:203 | 83.0 | 0.593 | T | -56.2 | -19.8 | 83.0 | 0.593 | 0.0 | ||||||
THR | B:215 | B:203 | 87.0 | 0.621 | T | -69.4 | -10.9 | 87.0 | 0.621 | 0.0 | |||||||||||||
1yz3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-02-07 | THR | A:203 | A:203 | 79.0 | 0.564 | T | -71.8 | -41.9 | 79.0 | 0.564 | 0.0 |
HOH |
9.305 |
OG1 |
O |
||
THR | B:203 | B:203 | 89.0 | 0.636 | T | -74.9 | -4.1 | 89.0 | 0.636 | 0.0 |
HOH |
3.024 |
CG2 |
O |
|||||||||
2an3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | THR | A:203 | A:203 | 85.0 | 0.607 | T | -67.3 | -15.0 | 85.0 | 0.607 | 0.0 |
HOH |
3.433 |
CA |
O |
||
THR | B:203 | B:703 | 87.0 | 0.621 | T | -76.3 | -9.0 | NA | NA | NA | |||||||||||||
2an4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | THR | A:203 | A:203 | 82.0 | 0.586 | T | -72.2 | -21.8 | 82.0 | 0.586 | 0.0 |
HOH |
3.037 |
CA |
O |
||
THR | B:203 | B:203 | 86.0 | 0.614 | T | -73.6 | -17.4 | NA | NA | NA | |||||||||||||
2an5 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | THR | A:203 | A:203 | 83.0 | 0.593 | T | -75.8 | -24.4 | 83.0 | 0.593 | 0.0 |
HOH |
4.083 |
CG2 |
O |
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THR | B:203 | B:203 | 85.0 | 0.607 | T | -69.8 | -14.7 | NA | NA | NA | |||||||||||||
2g70 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | THR | A:203 | A:203 | 79.0 | 0.564 | T | -83.6 | -13.5 | 79.0 | 0.564 | 0.0 |
HOH |
8.347 |
OG1 |
O |
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THR | B:203 | B:203 | 85.0 | 0.607 | T | -69.8 | -29.4 | NA | NA | NA | |||||||||||||
2g71 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | THR | A:203 | A:203 | 85.0 | 0.607 | T | -67.1 | -25.7 | 85.0 | 0.607 | 0.0 |
HOH |
3.431 |
O |
O |
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THR | B:203 | B:203 | 88.0 | 0.629 | T | -70.8 | -12.5 | NA | NA | NA | |||||||||||||
2g72 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | THR | A:203 | A:203 | 87.0 | 0.621 | T | -65.9 | -19.4 | 87.0 | 0.621 | 0.0 |
HOH |
3.395 |
CA |
O |
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THR | B:203 | B:203 | 88.0 | 0.629 | T | -71.5 | -8.2 | NA | NA | NA | |||||||||||||
2g8n | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-09-12 | THR | A:203 | A:203 | 83.0 | 0.593 | T | -62.8 | -23.8 | 83.0 | 0.593 | 0.0 |
HOH |
2.780 |
O |
O |
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THR | B:203 | B:203 | 83.0 | 0.593 | T | -66.6 | -18.3 | NA | NA | NA | |||||||||||||
2ony | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-10-09 | THR | A:203 | A:203 | 81.0 | 0.579 | T | -74.4 | -21.2 | 81.0 | 0.579 | 0.0 |
HOH |
3.624 |
CG2 |
O |
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THR | B:203 | B:703 | 85.0 | 0.607 | T | -66.7 | -16.7 | NA | NA | NA | |||||||||||||
3hcb | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | THR | A:203 | A:203 | 88.0 | 0.629 | T | -68.7 | -23.5 | 88.0 | 0.629 | 0.0 | ||||||
THR | B:203 | B:203 | 86.0 | 0.614 | G | -75.6 | -18.1 | NA | NA | NA | |||||||||||||
3hcc | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | THR | A:203 | A:203 | 79.0 | 0.564 | T | -60.8 | -24.1 | 79.0 | 0.564 | 0.0 |
HOH |
3.451 |
O |
O |
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THR | B:203 | B:203 | 85.0 | 0.607 | T | -66.5 | -22.1 | NA | NA | NA | |||||||||||||
3hcd | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | THR | A:203 | A:203 | 83.0 | 0.593 | T | -63.0 | -25.2 | 83.0 | 0.593 | 0.0 |
HOH |
3.595 |
OG1 |
O |
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THR | B:203 | B:203 | 84.0 | 0.6 | T | -60.2 | -28.3 | NA | NA | NA | |||||||||||||
3hcf | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | THR | A:203 | A:203 | 86.0 | 0.614 | T | -60.7 | -29.5 | 86.0 | 0.614 | 0.0 |
HOH |
3.265 |
OG1 |
O |
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THR | B:203 | B:203 | 87.0 | 0.621 | G | -77.7 | -18.9 | NA | NA | NA | |||||||||||||
3kpj | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 79.0 | 0.564 | T | -63.1 | -23.8 | 79.0 | 0.564 | 0.0 |
HOH |
4.217 |
OG1 |
O |
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THR | B:203 | B:203 | 85.0 | 0.607 | T | -65.4 | -22.3 | 85.0 | 0.607 | 0.0 |
HOH |
4.955 |
O |
O |
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3kpu | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 88.0 | 0.629 | T | -67.1 | -16.6 | 88.0 | 0.629 | 0.0 |
HOH |
3.460 |
CA |
O |
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THR | B:203 | B:203 | 87.0 | 0.621 | T | -65.3 | -21.6 | 87.0 | 0.621 | 0.0 |
HOH |
3.521 |
CA |
O |
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3kpv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 90.0 | 0.643 | T | -69.2 | -15.0 | 90.0 | 0.643 | 0.0 |
HOH |
3.679 |
CA |
O |
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THR | B:203 | B:203 | 92.0 | 0.657 | T | -64.0 | -17.7 | 92.0 | 0.657 | 0.0 |
HOH |
2.614 |
O |
O |
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3kpw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 87.0 | 0.621 | T | -65.4 | -18.1 | 87.0 | 0.621 | 0.0 |
HOH |
2.678 |
O |
O |
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THR | B:203 | B:203 | 86.0 | 0.614 | T | -74.9 | -10.6 | 86.0 | 0.614 | 0.0 |
HOH |
2.783 |
O |
O |
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3kpy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 86.0 | 0.614 | T | -67.7 | -20.0 | 86.0 | 0.614 | 0.0 |
HOH |
2.875 |
O |
O |
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THR | B:203 | B:203 | 86.0 | 0.614 | T | -66.0 | -14.5 | 86.0 | 0.614 | 0.0 |
HOH |
2.712 |
O |
O |
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3kqm | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 85.0 | 0.607 | T | -68.7 | -25.0 | 85.0 | 0.607 | 0.0 |
HOH |
8.987 |
OG1 |
O |
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THR | B:203 | B:203 | 88.0 | 0.629 | T | -69.7 | -20.2 | 88.0 | 0.629 | 0.0 |
HOH |
3.560 |
CA |
O |
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3kqo | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 84.0 | 0.6 | T | -67.8 | -20.3 | 84.0 | 0.6 | 0.0 |
HOH |
3.305 |
O |
O |
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THR | B:203 | B:203 | 86.0 | 0.614 | T | -69.0 | -11.4 | 86.0 | 0.614 | 0.0 |
HOH |
3.326 |
CG2 |
O |
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3kqp | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 83.0 | 0.593 | T | -69.0 | -21.6 | 83.0 | 0.593 | 0.0 |
HOH |
2.925 |
O |
O |
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THR | B:203 | B:203 | 87.0 | 0.621 | T | -63.8 | -19.1 | 87.0 | 0.621 | 0.0 |
HOH |
3.356 |
CG2 |
O |
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3kqq | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 83.0 | 0.593 | T | -62.0 | -29.1 | 83.0 | 0.593 | 0.0 |
HOH |
3.364 |
CA |
O |
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THR | B:203 | B:203 | 86.0 | 0.614 | T | -72.1 | -23.0 | 86.0 | 0.614 | 0.0 |
HOH |
5.253 |
OG1 |
O |
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3kqs | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 86.0 | 0.614 | T | -66.8 | -20.7 | 86.0 | 0.614 | 0.0 |
HOH |
3.210 |
O |
O |
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THR | B:203 | B:203 | 87.0 | 0.621 | T | -66.4 | -17.5 | 87.0 | 0.621 | 0.0 |
HOH |
2.745 |
O |
O |
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3kqt | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 88.0 | 0.629 | T | -63.3 | -18.8 | 88.0 | 0.629 | 0.0 |
HOH |
3.483 |
CA |
O |
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THR | B:203 | B:203 | 87.0 | 0.621 | T | -65.9 | -17.0 | 87.0 | 0.621 | 0.0 |
HOH |
3.426 |
OG1 |
O |
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3kqv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 85.0 | 0.607 | T | -63.4 | -23.9 | 85.0 | 0.607 | 0.0 |
HOH |
3.209 |
CG2 |
O |
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THR | B:203 | B:203 | 87.0 | 0.621 | T | -65.2 | -16.4 | 87.0 | 0.621 | 0.0 |
HOH |
3.447 |
CG2 |
O |
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3kqw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 84.0 | 0.6 | T | -73.6 | -19.3 | 84.0 | 0.6 | 0.0 |
HOH |
3.411 |
CG2 |
O |
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THR | B:203 | B:203 | 90.0 | 0.643 | T | -67.9 | -9.5 | 90.0 | 0.643 | 0.0 |
HOH |
3.177 |
OG1 |
O |
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3kqy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 84.0 | 0.6 | T | -66.6 | -20.7 | 84.0 | 0.6 | 0.0 |
HOH |
2.655 |
O |
O |
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THR | B:203 | B:203 | 86.0 | 0.614 | T | -70.9 | -18.5 | 86.0 | 0.614 | 0.0 |
HOH |
3.462 |
CG2 |
O |
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3kr0 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 82.0 | 0.586 | T | -71.5 | -27.6 | 82.0 | 0.586 | 0.0 |
HOH |
2.653 |
O |
O |
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THR | B:203 | B:203 | 85.0 | 0.607 | T | -74.7 | -16.4 | 85.0 | 0.607 | 0.0 |
HOH |
3.371 |
CG2 |
O |
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3kr1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 86.0 | 0.614 | T | -66.2 | -12.1 | 86.0 | 0.614 | 0.0 |
HOH |
3.293 |
CA |
O |
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THR | B:203 | B:203 | 86.0 | 0.614 | T | -65.6 | -15.3 | 86.0 | 0.614 | 0.0 |
HOH |
3.539 |
CG2 |
O |
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3kr2 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | THR | A:203 | A:203 | 80.0 | 0.571 | T | -61.5 | -24.6 | 80.0 | 0.571 | 0.0 |
HOH |
2.703 |
O |
O |
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THR | B:203 | B:203 | 86.0 | 0.614 | T | -65.7 | -17.2 | 86.0 | 0.614 | 0.0 |
HOH |
3.527 |
CG2 |
O |
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4dm3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2012-04-25 | THR | A:203 | A:203 | 87.0 | 0.621 | H | -64.9 | -23.8 | 87.0 | 0.621 | 0.0 |
HOH |
2.795 |
O |
O |
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THR | B:203 | B:203 | 87.0 | 0.621 | T | -69.4 | -11.0 | 87.0 | 0.621 | 0.0 |
HOH |
2.727 |
O |
O |
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4mik | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-09-10 | THR | A:203 | A:203 | 87.0 | 0.621 | T | -68.8 | -20.8 | 87.0 | 0.621 | 0.0 |
HOH |
2.955 |
HG22 |
O |
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THR | B:203 | B:203 | 86.0 | 0.614 | T | -66.3 | -16.4 | 86.0 | 0.614 | 0.0 |
HOH |
2.762 |
O |
O |
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4mq4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-10-15 | THR | A:203 | A:203 | 85.0 | 0.607 | T | -65.1 | -22.2 | 85.0 | 0.607 | 0.0 |
HOH |
2.937 |
HG23 |
O |
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THR | B:203 | B:203 | 85.0 | 0.607 | T | -71.0 | -20.0 | 85.0 | 0.607 | 0.0 |
HOH |
3.235 |
HG22 |
O |
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3hca | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | THR | A:203 | A:203 | 85.0 | 0.607 | T | -66.1 | -20.0 | 85.0 | 0.607 | 0.0 |
HOH |
3.138 |
O |
O |
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THR | B:203 | B:203 | 86.0 | 0.614 | T | -70.2 | -11.9 | NA | NA | NA | |||||||||||||
3hce | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | THR | A:203 | A:203 | 78.0 | 0.557 | T | -72.5 | -23.7 | 78.0 | 0.557 | 0.0 | ||||||
THR | B:203 | B:203 | 79.0 | 0.564 | T | -73.6 | -15.8 | NA | NA | NA | |||||||||||||
2obf | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | THR | A:203 | A:203 | 81.0 | 0.579 | T | -65.8 | -21.9 | 81.0 | 0.579 | 0.0 |
HOH |
2.935 |
O |
O |
||
THR | B:203 | B:703 | 87.0 | 0.621 | T | -69.1 | -15.9 | NA | NA | NA | |||||||||||||
2onz | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | THR | A:203 | A:203 | 81.0 | 0.579 | T | -63.4 | -23.0 | 81.0 | 0.579 | 0.0 |
HOH |
9.956 |
O |
O |
||
THR | B:203 | B:703 | 86.0 | 0.614 | T | -72.4 | -12.3 | NA | NA | NA | |||||||||||||
2opb | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | THR | A:203 | A:203 | 76.0 | 0.543 | T | -61.9 | -34.1 | 76.0 | 0.543 | 0.0 |
HOH |
6.106 |
OG1 |
O |
||
THR | B:203 | B:203 | 84.0 | 0.6 | T | -81.8 | -0.7 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p11086-f1 | 1 | P11086 | 100.0 | 0.0 | THR | A:203 | A:203 | 84.0 | 0.6 | T | -65.0 | -23.6 |