Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37826437 . G A CCDS11343.1:NM_002686.4:c.644gGg>gAg_NP_002677.1:p.215G>E Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1hnn 1 P11086 100.0 0.0 X-RAY
 2001-12-07 GLY A:215 A:215 0.0 0.0 E -163.7 176.8 0.0 0.0 0.0 SAH
SKF
HOH
 8.078
6.817
3.723
 CA
C
CA
 CB
C2
O
GLY B:215 B:715 0.0 0.0 E -159.0 169.0 NA NA NA
1n7i 1 P11086 100.0 0.0 X-RAY
 2003-12-23 GLY A:215 A:215 0.0 0.0 E -165.3 175.7 0.0 0.0 0.0 SAH
LY1
HOH
 8.103
6.546
5.546
 N
C
CA
 O
C1
O
GLY B:215 B:715 0.0 0.0 E -161.6 174.9 NA NA NA
1n7j 1 P11086 100.0 0.0 X-RAY
 2003-12-23 GLY A:215 A:215 0.0 0.0 E -169.2 179.6 0.0 0.0 0.0 SAH
IDI
HOH
 7.742
7.018
5.406
 N
C
CA
 O
C8
O
GLY B:215 B:715 0.0 0.0 E -154.7 179.0 NA NA NA
6ws1 1 P11086 100.0 0.0 X-RAY
 2020-08-05 GLY A:227 A:215 0.0 0.0 E -158.7 -179.3 0.0 0.0 0.0 SAH
CD
K
 8.387
7.330
7.315
 CA
C
C
 CB
CD
K
GLY B:227 B:215 0.0 0.0 E -147.8 170.0 0.0 0.0 0.0 U87
 6.672
 C
 C17
1yz3 1 P11086 100.0 0.0 X-RAY
 2006-02-07 GLY A:215 A:215 0.0 0.0 E -157.9 172.3 0.0 0.0 0.0 SKA
SAH
HOH
 6.679
7.791
3.843
 O
N
CA
 CL4
O
O
GLY B:215 B:215 0.0 0.0 E -167.3 171.1 0.0 0.0 0.0 SKA
SAH
HOH
 6.304
7.967
3.995
 O
N
CA
 CL4
O
O
2an3 1 P11086 100.0 0.0 X-RAY
 2006-03-14 GLY A:215 A:215 0.0 0.0 E -161.1 176.4 0.0 0.0 0.0 SAH
CTL
HOH
 7.820
6.382
3.911
 N
C
CA
 O
C1
O
GLY B:215 B:715 0.0 0.0 E -161.3 171.2 NA NA NA
2an4 1 P11086 100.0 0.0 X-RAY
 2006-03-14 GLY A:215 A:215 0.0 0.0 E -165.2 176.4 0.0 0.0 0.0 SAH
OTR
HOH
 7.775
6.601
3.715
 N
C
CA
 OXT
C7
O
GLY B:215 B:215 0.0 0.0 E -165.4 172.4 NA NA NA
2an5 1 P11086 100.0 0.0 X-RAY
 2006-03-14 GLY A:215 A:215 0.0 0.0 E -162.5 175.9 0.0 0.0 0.0 SAH
TTL
HOH
 7.807
6.457
3.776
 N
C
CA
 O
CAH
O
GLY B:215 B:215 0.0 0.0 E -161.5 174.7 NA NA NA
2g70 1 P11086 100.0 0.0 X-RAY
 2007-02-13 GLY A:215 A:215 0.0 0.0 E -158.1 176.4 0.0 0.0 0.0 SAM
HNT
HOH
 8.028
6.652
3.639
 N
C
CA
 O
C2
O
GLY B:215 B:215 0.0 0.0 E -171.8 176.3 NA NA NA
2g71 1 P11086 100.0 0.0 X-RAY
 2007-02-13 GLY A:215 A:215 0.0 0.0 E -169.2 172.2 0.0 0.0 0.0 SAH
FTS
HOH
 7.797
6.542
3.792
 N
O
CA
 O
O1
O
GLY B:215 B:215 0.0 0.0 E -159.3 171.0 NA NA NA
2g72 1 P11086 100.0 0.0 X-RAY
 2007-02-13 GLY A:215 A:215 0.0 0.0 E -168.3 179.8 0.0 0.0 0.0 SAM
F21
HOH
 7.864
6.649
3.860
 N
C
CA
 O
C1
O
GLY B:215 B:215 0.0 0.0 E -168.4 175.6 NA NA NA
2g8n 1 P11086 100.0 0.0 X-RAY
 2006-09-12 GLY A:215 A:215 0.0 0.0 E -164.6 177.1 0.0 0.0 0.0 F83
SAH
HOH
 6.561
7.909
3.745
 C
N
CA
 C3
OXT
O
GLY B:215 B:215 0.0 0.0 E -163.3 173.6 NA NA NA
2ony 1 P11086 100.0 0.0 X-RAY
 2007-10-09 GLY A:215 A:215 0.0 0.0 E -163.7 178.1 0.0 0.0 0.0 SAH
TMJ
HOH
 7.950
6.904
3.949
 N
C
CA
 OXT
C4
O
GLY B:215 B:715 0.0 0.0 E -159.9 172.8 NA NA NA
3hcb 1 P11086 100.0 0.0 X-RAY
 2009-08-25 GLY A:215 A:215 0.0 0.0 E -169.6 170.8 0.0 0.0 0.0 SAH
LT2
 7.885
6.454
 N
C
 O
CAE
GLY B:215 B:215 0.0 0.0 E -163.5 172.7 NA NA NA
3hcc 1 P11086 100.0 0.0 X-RAY
 2009-08-25 GLY A:215 A:215 0.0 0.0 E -161.6 175.2 0.0 0.0 0.0 LT3
SAH
HOH
 5.341
7.858
3.858
 O
N
CA
 F2
OXT
O
GLY B:215 B:215 0.0 0.0 E -157.9 172.3 NA NA NA
3hcd 1 P11086 100.0 0.0 X-RAY
 2009-08-25 GLY A:215 A:215 0.0 0.0 E -161.9 163.9 0.0 0.0 0.0 SAH
LNR
HOH
 7.663
6.506
3.751
 N
C
CA
 O
CAH
O
GLY B:215 B:215 0.0 0.0 E -164.9 165.6 NA NA NA
3hcf 1 P11086 100.0 0.0 X-RAY
 2009-08-25 GLY A:215 A:215 0.0 0.0 E -155.9 177.2 0.0 0.0 0.0 LT5
SAH
EDO
HOH
 6.383
7.710
3.554
5.474
 O
N
CA
C
 FAC
OXT
O2
O
GLY B:215 B:215 0.0 0.0 E -166.0 174.0 NA NA NA
3kpj 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -169.3 176.3 0.0 0.0 0.0 SAH
PO4
HOH
 7.757
6.472
3.948
 N
O
CA
 OXT
O2
O
GLY B:215 B:215 0.0 0.0 E -172.0 177.8 0.0 0.0 0.0 SAH
PO4
HOH
 8.042
6.473
3.874
 N
C
CA
 O
O2
O
3kpu 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -177.2 176.8 0.0 0.0 0.0 SAH
ES1
HOH
 7.869
6.826
5.279
 N
C
C
 O
CAM
O
GLY B:215 B:215 0.0 0.0 E -169.4 173.4 0.0 0.0 0.0 SAH
ES1
HOH
 8.107
6.701
3.709
 N
C
CA
 O
CAM
O
3kpv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -167.4 169.2 0.0 0.0 0.0 SAH
ADE
HOH
 7.849
6.841
5.203
 N
C
C
 O
C6
O
GLY B:215 B:215 0.0 0.0 E -165.9 173.7 0.0 0.0 0.0 SAH
ADE
HOH
 8.074
6.599
3.914
 N
C
CA
 O
N3
O
3kpw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -168.6 172.4 0.0 0.0 0.0 SAH
1SQ
HOH
 7.759
6.560
5.235
 N
C
C
 O
C2
O
GLY B:215 B:215 0.0 0.0 E -165.8 169.7 0.0 0.0 0.0 SAH
1SQ
HOH
 8.065
6.429
3.788
 N
C
CA
 O
C4
O
3kpy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -165.6 165.9 0.0 0.0 0.0 SAH
ES2
HOH
 7.828
6.761
5.133
 N
C
C
 O
C11
O
GLY B:215 B:215 0.0 0.0 E -162.0 171.4 0.0 0.0 0.0 SAH
ES2
HOH
 8.158
6.577
3.690
 N
C
CA
 O
C11
O
3kqm 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -177.6 172.8 0.0 0.0 0.0 SAH
ES3
HOH
 7.751
6.522
5.489
 N
C
C
 O
C02
O
GLY B:215 B:215 0.0 0.0 E -169.1 169.4 0.0 0.0 0.0 SAH
ES3
HOH
 8.099
6.391
3.886
 N
C
CA
 O
BR01
O
3kqo 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -167.2 169.4 0.0 0.0 0.0 SAH
ES4
HOH
 7.920
6.716
5.531
 N
C
C
 O
N05
O
GLY B:215 B:215 0.0 0.0 E -169.0 169.3 0.0 0.0 0.0 SAH
ES4
HOH
 7.962
6.525
3.761
 N
C
CA
 O
N05
O
3kqp 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -168.7 165.1 0.0 0.0 0.0 SAH
ES5
HOH
 7.869
6.627
5.263
 N
C
C
 O
C10
O
GLY B:215 B:215 0.0 0.0 E -171.3 170.5 0.0 0.0 0.0 SAH
ES5
HOH
 8.048
6.585
3.735
 CA
C
CA
 O
C10
O
3kqq 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -168.5 175.0 0.0 0.0 0.0 SAH
ES6
HOH
 7.922
6.500
4.517
 N
C
CA
 O
O10
O
GLY B:215 B:215 0.0 0.0 E -166.2 171.4 0.0 0.0 0.0 SAH
ES6
HOH
 8.169
6.304
3.871
 CA
C
CA
 O
C05
O
3kqs 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -166.4 167.6 0.0 0.0 0.0 SAH
AX7
HOH
 8.056
6.899
3.723
 N
C
CA
 O
NAG
O
GLY B:215 B:215 0.0 0.0 E -168.9 173.8 0.0 0.0 0.0 SAH
AX7
HOH
 8.085
6.752
3.784
 N
C
CA
 O
NAG
O
3kqt 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -159.3 166.3 0.0 0.0 0.0 SAH
ES7
HOH
 7.932
6.258
5.485
 N
C
C
 O
C01
O
GLY B:215 B:215 0.0 0.0 E -169.3 167.0 0.0 0.0 0.0 SAH
ES7
HOH
 8.015
6.062
3.745
 N
C
CA
 O
C01
O
3kqv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -165.7 167.9 0.0 0.0 0.0 SAH
FAN
 7.961
6.662
 N
C
 O
C2
GLY B:215 B:215 0.0 0.0 E -165.9 169.0 0.0 0.0 0.0 SAH
FAN
HOH
 8.122
6.671
3.725
 N
C
CA
 O
C3
O
3kqw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -163.7 176.6 0.0 0.0 0.0 SAH
ES9
 7.997
6.854
 N
C
 O
C09
GLY B:215 B:215 0.0 0.0 E -167.7 179.1 0.0 0.0 0.0 SAH
ES9
HOH
 7.954
6.760
3.717
 CA
C
CA
 O
C09
O
3kqy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -168.4 170.0 0.0 0.0 0.0 SAH
ES0
HOH
 7.804
6.776
4.050
 N
C
CA
 OXT
NAG
O
GLY B:215 B:215 0.0 0.0 E -167.9 170.9 0.0 0.0 0.0 SAH
ES0
HOH
 8.079
6.627
3.958
 CA
C
CA
 O
CAE
O
3kr0 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -169.5 177.1 0.0 0.0 0.0 SAH
172
HOH
 7.717
6.731
4.239
 CA
C
CA
 OXT
N10
O
GLY B:215 B:215 0.0 0.0 E -171.0 179.4 0.0 0.0 0.0 SAH
172
HOH
 7.970
6.535
5.845
 CA
C
CA
 O
N10
O
3kr1 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -162.9 163.9 0.0 0.0 0.0 SAH
VGD
HOH
 7.743
6.775
3.961
 N
C
CA
 OXT
NAF
O
GLY B:215 B:215 0.0 0.0 E -168.7 172.3 0.0 0.0 0.0 SAH
VGD
HOH
 7.950
6.572
3.866
 N
C
CA
 O
NAF
O
3kr2 1 P11086 100.0 0.0 X-RAY
 2010-09-29 GLY A:215 A:215 0.0 0.0 E -165.2 172.8 0.0 0.0 0.0 SAH
ET2
HOH
 7.714
6.729
4.033
 N
C
CA
 OXT
NAF
O
GLY B:215 B:215 0.0 0.0 E -166.2 171.6 0.0 0.0 0.0 SAH
ET2
HOH
 8.057
6.714
3.832
 N
C
CA
 O
NAF
O
4dm3 1 P11086 100.0 0.0 X-RAY
 2012-04-25 GLY A:215 A:215 0.0 0.0 E -166.9 165.6 0.0 0.0 0.0 SAH
RCO
IMD
HOH
 7.894
6.797
6.907
5.115
 N
C
O
C
 O
C3
C5
O
GLY B:215 B:215 0.0 0.0 E -162.8 168.2 0.0 0.0 0.0 SAH
RCO
IMD
HOH
 8.154
6.588
6.666
3.834
 N
C
O
CA
 O
C1
C4
O
4mik 1 P11086 100.0 0.0 X-RAY
 2014-09-10 GLY A:215 A:215 0.0 0.0 E -164.5 171.0 0.0 0.0 0.0 JIL
TRS
HOH
 5.505
5.956
3.223
 HA2
HA2
HA3
 H122
H31
O
GLY B:215 B:215 0.0 0.0 E -168.3 174.3 0.0 0.0 0.0 JIL
TRS
HOH
 5.688
6.318
3.090
 HA2
HA2
HA3
 H111
HO1
O
4mq4 1 P11086 100.0 0.0 X-RAY
 2014-10-15 GLY A:215 A:215 0.0 0.0 E -166.2 168.5 0.0 0.0 0.0 2D5
TRS
HOH
 5.205
5.984
3.243
 HA2
HA2
HA3
 H251
H12
O
GLY B:215 B:215 0.0 0.0 E -167.6 167.7 0.0 0.0 0.0 2D5
TRS
HOH
 5.206
6.143
3.487
 C
HA2
HA3
 H261
H21
O
3hca 1 P11086 99.65 0.0 X-RAY
 2009-08-25 GLY A:215 A:215 2.0 0.027 E -163.7 169.2 2.0 0.027 0.0 SAH
OTR
HOH
 7.737
6.692
3.396
 N
C
CA
 OXT
C7
O
GLY B:215 B:215 2.0 0.027 E -163.7 170.8 NA NA NA
3hce 1 P11086 99.65 0.0 X-RAY
 2009-08-25 GLY A:215 A:215 0.0 0.0 E -157.5 -169.7 0.0 0.0 0.0 SAH
OTR
HOH
 7.978
6.525
4.167
 CA
C
CA
 OXT
N8
O
GLY B:215 B:215 0.0 0.0 E -168.5 -177.4 NA NA NA
2obf 1 P11086 99.65 0.0 X-RAY
 2007-10-09 GLY A:215 A:215 0.0 0.0 E -166.1 174.5 0.0 0.0 0.0 F83
SAH
HOH
 6.491
7.799
3.776
 C
N
CA
 C2
OXT
O
GLY B:215 B:715 0.0 0.0 E -158.0 172.5 NA NA NA
2onz 1 P11086 99.65 0.0 X-RAY
 2007-10-09 GLY A:215 A:215 0.0 0.0 E 179.0 172.9 0.0 0.0 0.0 SAH
TMJ
HOH
 7.697
6.857
4.108
 N
C
CA
 OXT
C4
O
GLY B:215 B:715 0.0 0.0 E -168.3 167.6 NA NA NA
2opb 1 P11086 99.65 0.0 X-RAY
 2007-10-09 GLY A:215 A:215 0.0 0.0 E -173.7 175.5 0.0 0.0 0.0 F21
SAH
 6.711
7.999
 O
N
 O2
OXT
GLY B:215 B:215 0.0 0.0 E -163.0 -179.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11086-f1 1 P11086 100.0 0.0 GLY A:215 A:215 0.0 0.0 E -159.9 172.7