Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37826452 . C A CCDS11343.1:NM_002686.4:c.659tCg>tAg_NP_002677.1:p.220S>* Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1hnn 1 P11086 100.0 0.0 X-RAY
 2001-12-07 SER A:220 A:220 43.0 0.374 -115.4 -25.3 43.0 0.374 0.0 SKF
HOH
 8.123
2.829
 N
O
 N1
O
SER B:220 B:720 49.0 0.426 -109.2 -15.6 NA NA NA
1n7i 1 P11086 100.0 0.0 X-RAY
 2003-12-23 SER A:220 A:220 45.0 0.391 -130.1 -1.8 45.0 0.391 0.0 LY1
HOH
 8.457
6.719
 N
OG
 C2
O
SER B:220 B:720 46.0 0.4 -117.7 -25.6 NA NA NA
1n7j 1 P11086 100.0 0.0 X-RAY
 2003-12-23 SER A:220 A:220 41.0 0.357 -120.3 -26.8 41.0 0.357 0.0 IDI
HOH
 8.091
4.090
 N
OG
 N1
O
SER B:220 B:720 47.0 0.409 -114.6 -15.9 NA NA NA
6ws1 1 P11086 100.0 0.0 X-RAY
 2020-08-05 SER A:232 A:220 40.0 0.348 -125.1 -32.8 40.0 0.348 0.0 K
HOH
 8.330
9.012
 N
N
 K
O
SER B:232 B:220 34.0 0.296 -118.7 -18.3 34.0 0.296 0.0 U87
 8.548
 N
 C16
1yz3 1 P11086 100.0 0.0 X-RAY
 2006-02-07 SER A:220 A:220 44.0 0.383 -116.8 -23.6 44.0 0.383 0.0 SKA
HOH
 8.085
4.077
 N
OG
 N10
O
SER B:220 B:220 44.0 0.383 -117.0 -23.6 44.0 0.383 0.0 SKA
HOH
 8.257
4.435
 N
OG
 N10
O
2an3 1 P11086 100.0 0.0 X-RAY
 2006-03-14 SER A:220 A:220 41.0 0.357 -130.3 -11.3 41.0 0.357 0.0 CTL
HOH
 7.859
5.068
 N
OG
 O11
O
SER B:220 B:720 48.0 0.417 -116.3 -17.0 NA NA NA
2an4 1 P11086 100.0 0.0 X-RAY
 2006-03-14 SER A:220 A:220 42.0 0.365 -127.0 -15.1 42.0 0.365 0.0 OTR
HOH
 8.124
4.383
 N
OG
 O7
O
SER B:220 B:220 46.0 0.4 -119.3 -14.8 NA NA NA
2an5 1 P11086 100.0 0.0 X-RAY
 2006-03-14 SER A:220 A:220 40.0 0.348 -131.1 -7.4 40.0 0.348 0.0 TTL
HOH
 7.950
4.613
 N
OG
 CAH
O
SER B:220 B:220 47.0 0.409 -121.9 -11.7 NA NA NA
2g70 1 P11086 100.0 0.0 X-RAY
 2007-02-13 SER A:220 A:220 45.0 0.391 -116.8 -6.6 45.0 0.391 0.0 HNT
HOH
 7.562
4.535
 N
OG
 O22
O
SER B:220 B:220 46.0 0.4 -120.3 -23.6 NA NA NA
2g71 1 P11086 100.0 0.0 X-RAY
 2007-02-13 SER A:220 A:220 45.0 0.391 -118.8 -16.6 45.0 0.391 0.0 FTS
HOH
 7.907
2.943
 N
OG
 N1
O
SER B:220 B:220 48.0 0.417 -118.5 -14.3 NA NA NA
2g72 1 P11086 100.0 0.0 X-RAY
 2007-02-13 SER A:220 A:220 44.0 0.383 -127.3 -7.0 44.0 0.383 0.0 F21
HOH
 7.651
2.734
 N
OG
 F1
O
SER B:220 B:220 47.0 0.409 -124.5 -13.6 NA NA NA
2g8n 1 P11086 100.0 0.0 X-RAY
 2006-09-12 SER A:220 A:220 47.0 0.409 -118.4 -19.2 47.0 0.409 0.0 F83
HOH
 7.355
2.844
 N
O
 O1
O
SER B:220 B:220 47.0 0.409 -122.5 -16.0 NA NA NA
2ony 1 P11086 100.0 0.0 X-RAY
 2007-10-09 SER A:220 A:220 43.0 0.374 -119.6 -16.7 43.0 0.374 0.0 TMJ
HOH
 8.065
4.014
 N
OG
 N1
O
SER B:220 B:720 45.0 0.391 -122.5 -12.3 NA NA NA
3hcb 1 P11086 100.0 0.0 X-RAY
 2009-08-25 SER A:220 A:220 45.0 0.391 -111.7 -19.8 45.0 0.391 0.0 LT2
 7.770
 N
 OAB
SER B:220 B:220 44.0 0.383 -117.2 -17.7 NA NA NA
3hcc 1 P11086 100.0 0.0 X-RAY
 2009-08-25 SER A:220 A:220 45.0 0.391 -117.2 -22.7 45.0 0.391 0.0 LT3
HOH
 7.882
4.077
 N
OG
 N1
O
SER B:220 B:220 42.0 0.365 -122.5 -19.1 NA NA NA
3hcd 1 P11086 100.0 0.0 X-RAY
 2009-08-25 SER A:220 A:220 46.0 0.4 -127.5 -15.2 46.0 0.4 0.0 LNR
HOH
 8.115
4.714
 N
OG
 OAD
O
SER B:220 B:220 47.0 0.409 -118.1 -18.6 NA NA NA
3hcf 1 P11086 100.0 0.0 X-RAY
 2009-08-25 SER A:220 A:220 40.0 0.348 -128.1 -15.8 40.0 0.348 0.0 LT5
HOH
 8.202
4.046
 N
OG
 NAA
O
SER B:220 B:220 47.0 0.409 -111.4 -26.4 NA NA NA
3kpj 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 43.0 0.374 -130.6 -12.9 43.0 0.374 0.0 HOH
 4.477
 CB
 O
SER B:220 B:220 47.0 0.409 -115.4 -21.7 47.0 0.409 0.0 HOH
 5.326
 N
 O
3kpu 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 42.0 0.365 -119.2 -20.5 42.0 0.365 0.0 ES1
HOH
 9.433
2.833
 N
OG
 CAJ
O
SER B:220 B:220 45.0 0.391 -112.9 -21.6 45.0 0.391 0.0 ES1
HOH
 9.421
2.993
 N
O
 CAJ
O
3kpv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 42.0 0.365 -124.7 -18.0 42.0 0.365 0.0 ADE
HOH
 7.922
5.223
 N
N
 N1
O
SER B:220 B:220 45.0 0.391 -115.9 -14.0 45.0 0.391 0.0 ADE
HOH
 7.847
2.612
 N
O
 N1
O
3kpw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 44.0 0.383 -123.1 -17.4 44.0 0.383 0.0 1SQ
HOH
 8.335
5.322
 N
N
 N1
O
SER B:220 B:220 45.0 0.391 -116.4 -14.0 45.0 0.391 0.0 1SQ
HOH
 8.351
2.794
 N
O
 C4
O
3kpy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 43.0 0.374 -120.4 -19.0 43.0 0.374 0.0 ES2
HOH
 7.985
2.789
 N
OG
 CL01
O
SER B:220 B:220 48.0 0.417 -119.0 -16.2 48.0 0.417 0.0 ES2
HOH
 7.864
2.731
 N
O
 CL01
O
3kqm 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 41.0 0.357 -122.7 -22.7 41.0 0.357 0.0 ES3
HOH
 9.925
7.465
 N
O
 C03
O
SER B:220 B:220 46.0 0.4 -117.3 -19.8 46.0 0.4 0.0 HOH
 5.470
 N
 O
3kqo 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 43.0 0.374 -122.2 -16.6 43.0 0.374 0.0 ES4
HOH
 8.807
2.778
 N
OG
 C04
O
SER B:220 B:220 45.0 0.391 -111.5 -24.0 45.0 0.391 0.0 ES4
HOH
 8.884
3.111
 N
O
 C04
O
3kqp 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 41.0 0.357 -124.2 -23.9 41.0 0.357 0.0 ES5
HOH
 8.466
2.878
 N
OG
 N01
O
SER B:220 B:220 47.0 0.409 -115.7 -15.8 47.0 0.409 0.0 ES5
HOH
 8.639
2.631
 N
O
 N01
O
3kqq 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 43.0 0.374 -126.7 -19.7 43.0 0.374 0.0 ES6
HOH
 9.166
4.222
 N
CB
 O10
O
SER B:220 B:220 45.0 0.391 -123.2 -18.9 45.0 0.391 0.0 ES6
HOH
 8.874
2.728
 N
O
 O01
O
3kqs 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 43.0 0.374 -127.1 -16.9 43.0 0.374 0.0 HOH
 2.770
 O
 O
SER B:220 B:220 48.0 0.417 -119.3 -15.4 48.0 0.417 0.0 HOH
 2.815
 O
 O
3kqt 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 43.0 0.374 -122.0 -21.3 43.0 0.374 0.0 ES7
HOH
 8.682
5.100
 N
CB
 C01
O
SER B:220 B:220 45.0 0.391 -122.0 -17.8 45.0 0.391 0.0 ES7
HOH
 8.759
3.034
 N
O
 C01
O
3kqv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 43.0 0.374 -124.6 -16.6 43.0 0.374 0.0 FAN
HOH
 8.065
7.910
 N
CB
 O1
O
SER B:220 B:220 48.0 0.417 -117.9 -14.4 48.0 0.417 0.0 FAN
HOH
 7.984
2.774
 N
O
 C7
O
3kqw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 41.0 0.357 -129.2 -17.9 41.0 0.357 0.0 ES9
HOH
 9.148
8.021
 N
CB
 N08
O
SER B:220 B:220 45.0 0.391 -117.8 -19.0 45.0 0.391 0.0 ES9
HOH
 9.441
4.192
 N
O
 N08
O
3kqy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 42.0 0.365 -125.4 -20.1 42.0 0.365 0.0 ES0
HOH
 9.788
5.041
 N
N
 OAB
O
SER B:220 B:220 48.0 0.417 -119.5 -15.0 48.0 0.417 0.0 HOH
 3.039
 O
 O
3kr0 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 39.0 0.339 -121.8 -27.7 39.0 0.339 0.0 172
HOH
 9.031
4.936
 N
N
 N14
O
SER B:220 B:220 43.0 0.374 -120.9 -18.0 43.0 0.374 0.0 172
HOH
 9.381
5.084
 N
N
 N10
O
3kr1 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 45.0 0.391 -121.3 -18.3 45.0 0.391 0.0 VGD
HOH
 9.976
4.047
 N
OG
 NAF
O
SER B:220 B:220 44.0 0.383 -119.7 -18.5 44.0 0.383 0.0 VGD
HOH
 8.742
3.147
 N
O
 NAA
O
3kr2 1 P11086 100.0 0.0 X-RAY
 2010-09-29 SER A:220 A:220 41.0 0.357 -121.9 -18.2 41.0 0.357 0.0 HOH
 2.950
 OG
 O
SER B:220 B:220 47.0 0.409 -115.6 -16.6 47.0 0.409 0.0 HOH
 2.893
 O
 O
4dm3 1 P11086 100.0 0.0 X-RAY
 2012-04-25 SER A:220 A:220 44.0 0.383 -121.1 -19.6 44.0 0.383 0.0 RCO
HOH
 8.010
2.802
 N
OG
 C2
O
SER B:220 B:220 48.0 0.417 -119.2 -21.1 48.0 0.417 0.0 RCO
HOH
 8.000
2.893
 N
O
 O1
O
4mik 1 P11086 100.0 0.0 X-RAY
 2014-09-10 SER A:220 A:220 45.0 0.391 -120.7 -13.0 45.0 0.391 0.0 JIL
HOH
 6.913
2.699
 N
O
 H141
O
SER B:220 B:220 48.0 0.417 -115.5 -17.1 48.0 0.417 0.0 JIL
HOH
 7.047
2.791
 N
O
 H141
O
4mq4 1 P11086 100.0 0.0 X-RAY
 2014-10-15 SER A:220 A:220 45.0 0.391 -121.5 -16.3 45.0 0.391 0.0 2D5
HOH
 7.722
4.588
 H
HA
 O35
O
SER B:220 B:220 42.0 0.365 -122.2 -17.1 42.0 0.365 0.0 2D5
HOH
 7.275
2.873
 H
OG
 O35
O
3hca 1 P11086 99.65 0.0 X-RAY
 2009-08-25 SER A:220 A:220 43.0 0.374 -116.5 -14.1 43.0 0.374 0.0 OTR
HOH
 8.040
2.787
 N
OG
 O7
O
SER B:220 B:220 43.0 0.374 -118.2 -9.0 NA NA NA
3hce 1 P11086 99.65 0.0 X-RAY
 2009-08-25 SER A:220 A:220 40.0 0.348 -113.7 -23.2 40.0 0.348 0.0 OTR
HOH
 7.816
4.424
 N
OG
 N8
O
SER B:220 B:220 44.0 0.383 -108.2 -18.1 NA NA NA
2obf 1 P11086 99.65 0.0 X-RAY
 2007-10-09 SER A:220 A:220 44.0 0.383 -119.9 -14.9 44.0 0.383 0.0 F83
HOH
 7.261
3.056
 N
O
 O1
O
SER B:220 B:720 48.0 0.417 -120.4 -14.0 NA NA NA
2onz 1 P11086 99.65 0.0 X-RAY
 2007-10-09 SER A:220 A:220 40.0 0.348 -112.1 -6.4 40.0 0.348 0.0 TMJ
HOH
 8.210
4.071
 N
OG
 N1
O
SER B:220 B:720 44.0 0.383 -110.3 -12.1 NA NA NA
2opb 1 P11086 99.65 0.0 X-RAY
 2007-10-09 SER A:220 A:220 42.0 0.365 -130.8 -4.9 42.0 0.365 0.0 F21
HOH
 7.256
4.973
 N
OG
 F1
O
SER B:220 B:220 46.0 0.4 -112.9 -19.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11086-f1 1 P11086 100.0 0.0 SER A:220 A:220 47.0 0.409 -110.7 -15.9