Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37826482 . C A CCDS11343.1:NM_002686.4:c.689aCg>aAg_NP_002677.1:p.230T>K Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1hnn 1 P11086 100.0 0.0 X-RAY
 2001-12-07 THR A:230 A:230 89.0 0.636 E -100.9 125.4 89.0 0.636 0.0 SAH
HOH
 9.903
2.743
 O
OG1
 C8
O
THR B:230 B:730 121.0 0.864 E -89.4 135.7 NA NA NA
1n7i 1 P11086 100.0 0.0 X-RAY
 2003-12-23 THR A:230 A:230 74.0 0.529 E -94.0 131.6 74.0 0.529 0.0 SAH
LY1
HOH
 9.111
9.734
8.402
 O
C
OG1
 C8
C2
O
THR B:230 B:730 112.0 0.8 E -96.6 141.3 NA NA NA
1n7j 1 P11086 100.0 0.0 X-RAY
 2003-12-23 THR A:230 A:230 85.0 0.607 E -97.7 127.1 85.0 0.607 0.0 SAH
IDI
HOH
 9.559
9.579
6.128
 O
C
OG1
 N7
N1
O
THR B:230 B:730 121.0 0.864 E -85.5 139.6 NA NA NA
6ws1 1 P11086 100.0 0.0 X-RAY
 2020-08-05 THR A:242 A:230 86.0 0.614 E -119.5 129.3 86.0 0.614 0.0 SAH
K
 8.782
8.913
 O
C
 N7
K
THR B:242 B:230 85.0 0.607 E -116.8 128.2 85.0 0.607 0.0
1yz3 1 P11086 100.0 0.0 X-RAY
 2006-02-07 THR A:230 A:230 85.0 0.607 E -106.7 112.0 85.0 0.607 0.0 SKA
SAH
HOH
 9.690
9.895
6.113
 C
O
CG2
 C9
N7
O
THR B:230 B:230 122.0 0.871 E -88.5 126.0 122.0 0.871 0.0 SKA
SAH
HOH
 9.774
9.682
8.610
 C
O
C
 C9
C8
O
2an3 1 P11086 100.0 0.0 X-RAY
 2006-03-14 THR A:230 A:230 78.0 0.557 E -86.5 147.5 78.0 0.557 0.0 SAH
CTL
HOH
 8.893
7.515
6.575
 O
O
CG2
 C5'
N12
O
THR B:230 B:730 109.0 0.779 E -82.9 139.4 NA NA NA
2an4 1 P11086 100.0 0.0 X-RAY
 2006-03-14 THR A:230 A:230 86.0 0.614 E -86.5 148.4 86.0 0.614 0.0 SAH
OTR
HOH
 8.869
7.570
6.343
 O
O
O
 C5'
N8
O
THR B:230 B:230 100.0 0.714 E -88.6 134.0 NA NA NA
2an5 1 P11086 100.0 0.0 X-RAY
 2006-03-14 THR A:230 A:230 64.0 0.457 E -88.9 144.7 64.0 0.457 0.0 SAH
TTL
HOH
 8.944
8.470
7.318
 O
O
O
 C5'
NAA
O
THR B:230 B:230 100.0 0.714 E -88.6 127.8 NA NA NA
2g70 1 P11086 100.0 0.0 X-RAY
 2007-02-13 THR A:230 A:230 90.0 0.643 E -101.5 121.2 90.0 0.643 0.0 SAM
HNT
 9.311
7.486
 O
C
 CE
O22
THR B:230 B:230 91.0 0.65 E -84.4 132.6 NA NA NA
2g71 1 P11086 100.0 0.0 X-RAY
 2007-02-13 THR A:230 A:230 73.0 0.521 E -84.8 149.5 73.0 0.521 0.0 SAH
FTS
HOH
 9.099
7.166
2.799
 O
O
O
 C5'
F4
O
THR B:230 B:230 113.0 0.807 E -86.1 135.6 NA NA NA
2g72 1 P11086 100.0 0.0 X-RAY
 2007-02-13 THR A:230 A:230 80.0 0.571 E -88.6 151.8 80.0 0.571 0.0 SAM
F21
HOH
 8.386
6.596
2.871
 O
O
O
 CE
F1
O
THR B:230 B:230 105.0 0.75 E -92.7 141.7 NA NA NA
2g8n 1 P11086 100.0 0.0 X-RAY
 2006-09-12 THR A:230 A:230 82.0 0.586 E -91.8 136.4 82.0 0.586 0.0 F83
SAH
HOH
 7.243
9.239
2.671
 O
O
O
 O1
C8
O
THR B:230 B:230 119.0 0.85 E -84.6 138.1 NA NA NA
2ony 1 P11086 100.0 0.0 X-RAY
 2007-10-09 THR A:230 A:230 86.0 0.614 E -92.4 146.2 86.0 0.614 0.0 SAH
TMJ
HOH
 9.127
8.693
7.681
 O
O
O
 C5'
C2
O
THR B:230 B:730 119.0 0.85 E -96.8 130.2 NA NA NA
3hcb 1 P11086 100.0 0.0 X-RAY
 2009-08-25 THR A:230 A:230 83.0 0.593 E -93.0 138.6 83.0 0.593 0.0 SAH
LT2
 9.148
9.221
 O
O
 C8
OAA
THR B:230 B:230 105.0 0.75 E -93.7 139.3 NA NA NA
3hcc 1 P11086 100.0 0.0 X-RAY
 2009-08-25 THR A:230 A:230 68.0 0.486 E -91.1 139.0 68.0 0.486 0.0 LT3
SAH
HOH
 8.010
8.903
6.302
 O
O
OG1
 N1
C8
O
THR B:230 B:230 79.0 0.564 E -94.3 134.8 NA NA NA
3hcd 1 P11086 100.0 0.0 X-RAY
 2009-08-25 THR A:230 A:230 81.0 0.579 E -86.1 145.2 81.0 0.579 0.0 SAH
LNR
HOH
 9.151
7.694
2.950
 O
O
O
 C8
NAA
O
THR B:230 B:230 104.0 0.743 E -101.3 129.0 NA NA NA
3hcf 1 P11086 100.0 0.0 X-RAY
 2009-08-25 THR A:230 A:230 82.0 0.586 E -97.7 144.1 82.0 0.586 0.0 LT5
SAH
HOH
 8.208
9.090
5.796
 O
O
OG1
 NAA
C8
O
THR B:230 B:230 105.0 0.75 E -99.7 134.8 NA NA NA
3kpj 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 84.0 0.6 E -90.7 138.3 84.0 0.6 0.0 SAH
HOH
 9.048
2.876
 O
O
 C8
O
THR B:230 B:230 99.0 0.707 E -101.4 115.9 99.0 0.707 0.0 SAH
HOH
 9.335
8.440
 O
C
 C8
O
3kpu 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 84.0 0.6 E -93.7 143.0 84.0 0.6 0.0 SAH
HOH
 8.923
2.920
 O
O
 C8
O
THR B:230 B:230 100.0 0.714 E -92.9 138.4 100.0 0.714 0.0 SAH
HOH
 9.066
2.902
 O
O
 C8
O
3kpv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 83.0 0.593 E -88.8 138.0 83.0 0.593 0.0 SAH
ADE
HOH
 9.045
8.392
7.947
 O
O
O
 C8
N6
O
THR B:230 B:230 106.0 0.757 E -89.1 118.9 106.0 0.757 0.0 SAH
ADE
HOH
 9.670
8.820
3.316
 O
C
OG1
 N7
N6
O
3kpw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 81.0 0.579 E -88.0 145.1 81.0 0.579 0.0 SAH
1SQ
HOH
 8.900
9.958
7.552
 O
O
O
 C5'
N3
O
THR B:230 B:230 104.0 0.743 E -89.0 133.3 104.0 0.743 0.0 SAH
HOH
 9.208
2.943
 O
CG2
 C8
O
3kpy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 89.0 0.636 E -92.0 140.7 89.0 0.636 0.0 SAH
ES2
HOH
 8.870
8.459
5.921
 O
O
O
 C8
CL01
O
THR B:230 B:230 106.0 0.757 E -92.0 122.6 106.0 0.757 0.0 SAH
ES2
HOH
 9.377
8.965
3.034
 O
C
CG2
 N7
CL01
O
3kqm 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 83.0 0.593 E -91.5 141.7 83.0 0.593 0.0 SAH
HOH
 8.672
3.821
 O
CG2
 C5'
O
THR B:230 B:230 102.0 0.729 E -94.0 135.7 102.0 0.729 0.0 SAH
HOH
 8.923
7.877
 O
N
 C5'
O
3kqo 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 85.0 0.607 E -96.2 143.9 85.0 0.607 0.0 SAH
HOH
 8.794
3.753
 O
CG2
 C5'
O
THR B:230 B:230 103.0 0.736 E -95.3 126.9 103.0 0.736 0.0 SAH
HOH
 9.312
3.376
 O
CG2
 C8
O
3kqp 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 85.0 0.607 E -85.8 145.1 85.0 0.607 0.0 SAH
ES5
HOH
 8.862
9.028
2.914
 O
O
O
 C8
N01
O
THR B:230 B:230 100.0 0.714 E -90.6 133.7 100.0 0.714 0.0 SAH
ES5
HOH
 9.176
9.247
3.763
 O
C
OG1
 C8
N01
O
3kqq 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 79.0 0.564 E -83.1 142.8 79.0 0.564 0.0 SAH
HOH
 8.800
7.601
 O
O
 C5'
O
THR B:230 B:230 100.0 0.714 E -100.2 135.0 100.0 0.714 0.0 SAH
HOH
 8.918
2.608
 O
OG1
 C5'
O
3kqs 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 90.0 0.643 E -84.3 141.7 90.0 0.643 0.0 SAH
HOH
 8.916
3.559
 O
CG2
 C5'
O
THR B:230 B:230 112.0 0.8 E -88.3 139.6 112.0 0.8 0.0 SAH
HOH
 8.964
2.731
 O
O
 C5'
O
3kqt 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 88.0 0.629 E -93.4 140.1 88.0 0.629 0.0 SAH
HOH
 8.781
6.096
 O
O
 C5'
O
THR B:230 B:230 106.0 0.757 E -91.7 142.9 106.0 0.757 0.0 SAH
HOH
 8.775
3.109
 O
CG2
 C5'
O
3kqv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 88.0 0.629 E -90.7 139.6 88.0 0.629 0.0 SAH
FAN
HOH
 8.953
8.649
5.837
 O
O
O
 C8
O1
O
THR B:230 B:230 105.0 0.75 E -93.5 133.7 105.0 0.75 0.0 SAH
FAN
HOH
 9.254
9.105
3.173
 O
C
CG2
 C8
O1
O
3kqw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 82.0 0.586 E -102.3 141.0 82.0 0.586 0.0 SAH
HOH
 8.891
6.899
 O
CG2
 C8
O
THR B:230 B:230 101.0 0.721 E -98.8 134.5 101.0 0.721 0.0 SAH
HOH
 9.162
3.365
 O
CG2
 C8
O
3kqy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 85.0 0.607 E -89.4 143.4 85.0 0.607 0.0 SAH
HOH
 8.946
2.844
 O
O
 C5'
O
THR B:230 B:230 105.0 0.75 E -97.8 136.2 105.0 0.75 0.0 SAH
HOH
 9.236
3.444
 O
CG2
 C5'
O
3kr0 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 81.0 0.579 E -96.3 152.3 81.0 0.579 0.0 SAH
172
HOH
 8.959
8.793
7.160
 O
O
O
 C5'
N14
O
THR B:230 B:230 108.0 0.771 E -106.9 138.6 108.0 0.771 0.0 SAH
172
HOH
 9.318
9.610
2.876
 O
O
N
 C8
N14
O
3kr1 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 86.0 0.614 E -97.2 135.9 86.0 0.614 0.0 SAH
HOH
 9.066
7.864
 O
O
 C8
O
THR B:230 B:230 109.0 0.779 E -93.7 132.7 109.0 0.779 0.0 SAH
VGD
HOH
 9.481
8.801
3.878
 O
O
CG2
 C8
NAA
O
3kr2 1 P11086 100.0 0.0 X-RAY
 2010-09-29 THR A:230 A:230 85.0 0.607 E -86.8 147.3 85.0 0.607 0.0 SAH
HOH
 8.987
2.912
 O
O
 C5'
O
THR B:230 B:230 111.0 0.793 E -99.5 139.3 111.0 0.793 0.0 SAH
HOH
 9.164
3.548
 O
CG2
 C5'
O
4dm3 1 P11086 100.0 0.0 X-RAY
 2012-04-25 THR A:230 A:230 87.0 0.621 E -93.2 141.0 87.0 0.621 0.0 SAH
RCO
HOH
 8.932
7.642
2.752
 O
O
O
 C8
O1
O
THR B:230 B:230 105.0 0.75 E -90.9 120.1 105.0 0.75 0.0 SAH
RCO
HOH
 9.381
9.087
2.443
 O
O
O
 C8
O3
O
4mik 1 P11086 100.0 0.0 X-RAY
 2014-09-10 THR A:230 A:230 88.0 0.629 E -84.8 140.9 88.0 0.629 0.0 JIL
HOH
 6.481
2.060
 O
H
 H111
O
THR B:230 B:230 113.0 0.807 E -91.2 137.4 113.0 0.807 0.0 JIL
HOH
 6.966
2.256
 O
H
 H121
O
4mq4 1 P11086 100.0 0.0 X-RAY
 2014-10-15 THR A:230 A:230 109.0 0.779 E -89.6 135.4 109.0 0.779 0.0 2D5
HOH
 7.963
2.066
 O
H
 H211
O
THR B:230 B:230 87.0 0.621 E -82.3 139.1 87.0 0.621 0.0 2D5
HOH
 7.195
3.006
 O
O
 H231
O
3hca 1 P11086 99.65 0.0 X-RAY
 2009-08-25 THR A:230 A:230 90.0 0.643 E -102.7 118.5 90.0 0.643 0.0 OTR
HOH
 9.055
4.057
 C
OG1
 N8
O
THR B:230 B:230 119.0 0.85 E -98.9 113.0 NA NA NA
3hce 1 P11086 99.65 0.0 X-RAY
 2009-08-25 THR A:230 A:230 92.0 0.657 E -98.1 138.2 92.0 0.657 0.0 SAH
OTR
HOH
 9.650
8.696
4.869
 O
C
OG1
 C8
N8
O
THR B:230 B:230 118.0 0.843 E -94.0 142.1 NA NA NA
2obf 1 P11086 99.65 0.0 X-RAY
 2007-10-09 THR A:230 A:230 86.0 0.614 E -91.0 137.5 86.0 0.614 0.0 F83
SAH
HOH
 7.106
9.199
2.819
 O
O
O
 O1
C8
O
THR B:230 B:730 119.0 0.85 E -86.1 137.9 NA NA NA
2onz 1 P11086 99.65 0.0 X-RAY
 2007-10-09 THR A:230 A:230 95.0 0.679 E -97.0 115.7 95.0 0.679 0.0 TMJ
HOH
 9.715
4.638
 C
OG1
 C2
O
THR B:230 B:730 120.0 0.857 E -95.4 134.7 NA NA NA
2opb 1 P11086 99.65 0.0 X-RAY
 2007-10-09 THR A:230 A:230 88.0 0.629 E -84.9 144.3 88.0 0.629 0.0 F21
SAH
HOH
 6.541
8.767
8.297
 O
O
CG2
 F1
C5'
O
THR B:230 B:230 105.0 0.75 E -89.1 119.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11086-f1 1 P11086 100.0 0.0 THR A:230 A:230 86.0 0.614 E -76.8 139.9