Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr17 | 37826497 | . | C | A | CCDS11343.1:NM_002686.4:c.704tCt>tAt_NP_002677.1:p.235S>Y | Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1hnn | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2001-12-07 | SER | A:235 | A:235 | 25.0 | 0.217 | -111.3 | 168.0 | 25.0 | 0.217 | 0.0 |
HOH |
3.044 |
CA |
O |
|||
SER | B:235 | B:735 | 24.0 | 0.209 | -109.0 | 174.5 | NA | NA | NA | ||||||||||||||
1n7i | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | SER | A:235 | A:235 | 29.0 | 0.252 | -118.9 | 168.3 | 29.0 | 0.252 | 0.0 | |||||||
SER | B:235 | B:735 | 26.0 | 0.226 | -101.7 | 163.5 | NA | NA | NA | ||||||||||||||
1n7j | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | SER | A:235 | A:235 | 27.0 | 0.235 | -123.6 | 158.9 | 27.0 | 0.235 | 0.0 |
HOH |
3.388 |
CA |
O |
|||
SER | B:235 | B:735 | 29.0 | 0.252 | -99.2 | 164.4 | NA | NA | NA | ||||||||||||||
6ws1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2020-08-05 | SER | A:247 | A:235 | 24.0 | 0.209 | -127.7 | 165.6 | 24.0 | 0.209 | 0.0 |
HOH |
4.584 |
OG |
O |
|||
SER | B:247 | B:235 | 23.0 | 0.2 | -139.8 | 164.4 | 23.0 | 0.2 | 0.0 | ||||||||||||||
1yz3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-02-07 | SER | A:235 | A:235 | 25.0 | 0.217 | -99.0 | 169.0 | 18.0 | 0.157 | 0.06 |
B:P11086:0.061 |
HOH |
3.389 |
CB |
O |
||
SER | B:235 | B:235 | 23.0 | 0.2 | -107.7 | 176.5 | 23.0 | 0.2 | 0.0 |
HOH |
3.085 |
OG |
O |
||||||||||
2an3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | SER | A:235 | A:235 | 30.0 | 0.261 | -111.1 | 172.0 | 30.0 | 0.261 | 0.0 |
HOH |
3.262 |
OG |
O |
|||
SER | B:235 | B:735 | 24.0 | 0.209 | -105.7 | 167.6 | NA | NA | NA | ||||||||||||||
2an4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | SER | A:235 | A:235 | 28.0 | 0.243 | -113.5 | 173.9 | 28.0 | 0.243 | 0.0 |
HOH |
3.285 |
CA |
O |
|||
SER | B:235 | B:235 | 28.0 | 0.243 | -111.0 | 167.2 | NA | NA | NA | ||||||||||||||
2an5 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | SER | A:235 | A:235 | 27.0 | 0.235 | -108.4 | 167.1 | 27.0 | 0.235 | 0.0 |
HOH |
3.147 |
CA |
O |
|||
SER | B:235 | B:235 | 26.0 | 0.226 | -105.7 | 170.5 | NA | NA | NA | ||||||||||||||
2g70 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | SER | A:235 | A:235 | 27.0 | 0.235 | -112.6 | 157.2 | 27.0 | 0.235 | 0.0 |
HNT HOH |
9.331 3.191 |
O CA |
O22 O |
|||
SER | B:235 | B:235 | 23.0 | 0.2 | -114.6 | 163.8 | NA | NA | NA | ||||||||||||||
2g71 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | SER | A:235 | A:235 | 29.0 | 0.252 | -113.1 | 170.0 | 29.0 | 0.252 | 0.0 |
HOH |
2.879 |
OG |
O |
|||
SER | B:235 | B:235 | 25.0 | 0.217 | -109.0 | 170.3 | NA | NA | NA | ||||||||||||||
2g72 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | SER | A:235 | A:235 | 29.0 | 0.252 | -108.7 | 165.4 | 29.0 | 0.252 | 0.0 |
HOH |
2.832 |
OG |
O |
|||
SER | B:235 | B:235 | 23.0 | 0.2 | -114.5 | 168.6 | NA | NA | NA | ||||||||||||||
2g8n | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-09-12 | SER | A:235 | A:235 | 24.0 | 0.209 | -108.9 | 167.4 | 24.0 | 0.209 | 0.0 |
HOH |
2.888 |
OG |
O |
|||
SER | B:235 | B:235 | 24.0 | 0.209 | -109.5 | 162.5 | NA | NA | NA | ||||||||||||||
2ony | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-10-09 | SER | A:235 | A:235 | 30.0 | 0.261 | -109.9 | 168.6 | 30.0 | 0.261 | 0.0 |
HOH |
3.210 |
CA |
O |
|||
SER | B:235 | B:735 | 27.0 | 0.235 | -119.0 | 171.3 | NA | NA | NA | ||||||||||||||
3hcb | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | SER | A:235 | A:235 | 27.0 | 0.235 | -113.3 | 170.7 | 27.0 | 0.235 | 0.0 | |||||||
SER | B:235 | B:235 | 23.0 | 0.2 | -108.0 | 168.6 | NA | NA | NA | ||||||||||||||
3hcc | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | SER | A:235 | A:235 | 31.0 | 0.27 | -118.3 | 169.7 | 31.0 | 0.27 | 0.0 |
HOH |
3.202 |
OG |
O |
|||
SER | B:235 | B:235 | 28.0 | 0.243 | -112.0 | 167.9 | NA | NA | NA | ||||||||||||||
3hcd | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | SER | A:235 | A:235 | 30.0 | 0.261 | -116.4 | 171.0 | 30.0 | 0.261 | 0.0 |
HOH |
3.450 |
CA |
O |
|||
SER | B:235 | B:235 | 32.0 | 0.278 | -111.6 | 170.4 | NA | NA | NA | ||||||||||||||
3hcf | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | SER | A:235 | A:235 | 23.0 | 0.2 | -136.0 | 164.0 | 23.0 | 0.2 | 0.0 |
EDO HOH |
9.561 9.956 |
O N |
O2 O |
|||
SER | B:235 | B:235 | 29.0 | 0.252 | -129.9 | 170.8 | NA | NA | NA | ||||||||||||||
3kpj | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 29.0 | 0.252 | -133.2 | 164.5 | 29.0 | 0.252 | 0.0 |
HOH |
3.550 |
CB |
O |
|||
SER | B:235 | B:235 | 31.0 | 0.27 | -120.3 | 166.4 | 31.0 | 0.27 | 0.0 |
HOH |
3.437 |
CA |
O |
||||||||||
3kpu | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 32.0 | 0.278 | -96.6 | 161.6 | 32.0 | 0.278 | 0.0 |
HOH |
3.164 |
CB |
O |
|||
SER | B:235 | B:235 | 33.0 | 0.287 | -111.3 | 169.4 | 33.0 | 0.287 | 0.0 |
HOH |
3.474 |
CA |
O |
||||||||||
3kpv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 33.0 | 0.287 | -104.8 | 165.9 | 33.0 | 0.287 | 0.0 |
HOH |
3.012 |
OG |
O |
|||
SER | B:235 | B:235 | 31.0 | 0.27 | -108.2 | 171.1 | 31.0 | 0.27 | 0.0 |
HOH |
3.430 |
CA |
O |
||||||||||
3kpw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 31.0 | 0.27 | -101.8 | 164.6 | 31.0 | 0.27 | 0.0 |
HOH |
3.045 |
CB |
O |
|||
SER | B:235 | B:235 | 32.0 | 0.278 | -108.4 | 173.1 | 32.0 | 0.278 | 0.0 |
HOH |
3.302 |
CB |
O |
||||||||||
3kpy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 31.0 | 0.27 | -104.2 | 168.4 | 31.0 | 0.27 | 0.0 |
HOH |
3.379 |
CB |
O |
|||
SER | B:235 | B:235 | 33.0 | 0.287 | -102.5 | 168.8 | 33.0 | 0.287 | 0.0 |
HOH |
2.656 |
OG |
O |
||||||||||
3kqm | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 31.0 | 0.27 | -110.2 | 169.5 | 31.0 | 0.27 | 0.0 |
HOH |
3.107 |
OG |
O |
|||
SER | B:235 | B:235 | 33.0 | 0.287 | -106.7 | 172.0 | 33.0 | 0.287 | 0.0 |
HOH |
3.419 |
N |
O |
||||||||||
3kqo | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 30.0 | 0.261 | -98.3 | 164.2 | 30.0 | 0.261 | 0.0 |
HOH |
2.786 |
OG |
O |
|||
SER | B:235 | B:235 | 30.0 | 0.261 | -106.4 | 167.2 | 30.0 | 0.261 | 0.0 |
HOH |
2.793 |
OG |
O |
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3kqp | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 28.0 | 0.243 | -109.9 | 167.4 | 28.0 | 0.243 | 0.0 |
HOH |
3.202 |
CA |
O |
|||
SER | B:235 | B:235 | 33.0 | 0.287 | -104.0 | 168.3 | 33.0 | 0.287 | 0.0 |
HOH |
3.278 |
CB |
O |
||||||||||
3kqq | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 29.0 | 0.252 | -102.2 | 165.0 | 29.0 | 0.252 | 0.0 |
HOH |
3.068 |
CB |
O |
|||
SER | B:235 | B:235 | 34.0 | 0.296 | -113.9 | 173.1 | 34.0 | 0.296 | 0.0 |
HOH |
3.332 |
CB |
O |
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3kqs | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 32.0 | 0.278 | -102.3 | 166.6 | 32.0 | 0.278 | 0.0 |
HOH |
3.475 |
CB |
O |
|||
SER | B:235 | B:235 | 32.0 | 0.278 | -105.0 | 169.8 | 32.0 | 0.278 | 0.0 |
HOH |
2.721 |
OG |
O |
||||||||||
3kqt | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 31.0 | 0.27 | -106.2 | 170.0 | 31.0 | 0.27 | 0.0 |
HOH |
3.508 |
CB |
O |
|||
SER | B:235 | B:235 | 34.0 | 0.296 | -106.9 | 173.2 | 34.0 | 0.296 | 0.0 |
HOH |
3.312 |
CA |
O |
||||||||||
3kqv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 33.0 | 0.287 | -102.6 | 169.7 | 33.0 | 0.287 | 0.0 |
HOH |
3.219 |
CB |
O |
|||
SER | B:235 | B:235 | 31.0 | 0.27 | -102.8 | 171.8 | 31.0 | 0.27 | 0.0 |
HOH |
2.630 |
OG |
O |
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3kqw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 32.0 | 0.278 | -106.6 | 165.9 | 32.0 | 0.278 | 0.0 |
HOH |
3.392 |
OG |
O |
|||
SER | B:235 | B:235 | 32.0 | 0.278 | -104.1 | 168.7 | 32.0 | 0.278 | 0.0 |
HOH |
3.502 |
CA |
O |
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3kqy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 25.0 | 0.217 | -107.8 | 168.7 | 25.0 | 0.217 | 0.0 |
HOH |
3.307 |
CA |
O |
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SER | B:235 | B:235 | 30.0 | 0.261 | -112.6 | 169.5 | 30.0 | 0.261 | 0.0 |
HOH |
3.484 |
CA |
O |
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3kr0 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 27.0 | 0.235 | -129.7 | 167.1 | 27.0 | 0.235 | 0.0 |
HOH |
3.129 |
CA |
O |
|||
SER | B:235 | B:235 | 32.0 | 0.278 | -119.4 | 174.4 | 32.0 | 0.278 | 0.0 |
HOH |
3.347 |
CB |
O |
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3kr1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 31.0 | 0.27 | -104.5 | 171.4 | 31.0 | 0.27 | 0.0 |
HOH |
3.233 |
CA |
O |
|||
SER | B:235 | B:235 | 23.0 | 0.2 | -108.1 | 171.5 | 23.0 | 0.2 | 0.0 |
HOH |
3.335 |
CA |
O |
||||||||||
3kr2 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | SER | A:235 | A:235 | 31.0 | 0.27 | -110.9 | 171.3 | 31.0 | 0.27 | 0.0 |
HOH |
3.205 |
CA |
O |
|||
SER | B:235 | B:235 | 31.0 | 0.27 | -116.0 | 166.6 | 31.0 | 0.27 | 0.0 |
HOH |
3.251 |
CA |
O |
||||||||||
4dm3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2012-04-25 | SER | A:235 | A:235 | 30.0 | 0.261 | -104.7 | 166.4 | 30.0 | 0.261 | 0.0 |
HOH |
3.383 |
CA |
O |
|||
SER | B:235 | B:235 | 31.0 | 0.27 | -101.7 | 165.5 | 31.0 | 0.27 | 0.0 |
HOH |
2.755 |
OG |
O |
||||||||||
4mik | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-09-10 | SER | A:235 | A:235 | 32.0 | 0.278 | -103.7 | 166.8 | 32.0 | 0.278 | 0.0 |
HOH |
1.948 |
HG |
O |
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SER | B:235 | B:235 | 16.0 | 0.139 | -108.6 | 165.6 | 16.0 | 0.139 | 0.0 |
HOH |
1.864 |
HG |
O |
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4mq4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-10-15 | SER | A:235 | A:235 | 22.0 | 0.191 | -108.7 | 169.6 | 22.0 | 0.191 | 0.0 |
HOH |
2.894 |
HB2 |
O |
|||
SER | B:235 | B:235 | 24.0 | 0.209 | -104.2 | 164.9 | 24.0 | 0.209 | 0.0 |
HOH |
2.532 |
HB2 |
O |
||||||||||
3hca | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | SER | A:235 | A:235 | 28.0 | 0.243 | -109.4 | 171.0 | 28.0 | 0.243 | 0.0 |
HOH |
3.231 |
CB |
O |
|||
SER | B:235 | B:235 | 23.0 | 0.2 | -117.6 | 172.6 | NA | NA | NA | ||||||||||||||
3hce | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | SER | A:235 | A:235 | 29.0 | 0.252 | -117.3 | 170.8 | 29.0 | 0.252 | 0.0 |
HOH |
6.767 |
OG |
O |
|||
SER | B:235 | B:235 | 14.0 | 0.122 | -109.1 | 166.4 | NA | NA | NA | ||||||||||||||
2obf | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | SER | A:235 | A:235 | 34.0 | 0.296 | -113.3 | 169.3 | 34.0 | 0.296 | 0.0 |
HOH |
2.777 |
OG |
O |
|||
SER | B:235 | B:735 | 31.0 | 0.27 | -113.5 | 167.7 | NA | NA | NA | ||||||||||||||
2onz | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | SER | A:235 | A:235 | 33.0 | 0.287 | -93.8 | 178.1 | 33.0 | 0.287 | 0.0 |
HOH |
3.025 |
OG |
O |
|||
SER | B:235 | B:735 | 13.0 | 0.113 | -105.5 | 167.6 | NA | NA | NA | ||||||||||||||
2opb | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | SER | A:235 | A:235 | 29.0 | 0.252 | -118.4 | 166.0 | 29.0 | 0.252 | 0.0 |
HOH |
3.436 |
OG |
O |
|||
SER | B:235 | B:235 | 32.0 | 0.278 | -98.4 | 170.5 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p11086-f1 | 1 | P11086 | 100.0 | 0.0 | SER | A:235 | A:235 | 28.0 | 0.243 | -94.0 | 164.9 |