Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr17 | 37826502 | . | G | A | CCDS11343.1:NM_002686.4:c.709Gag>Aag_NP_002677.1:p.237E>K | Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
1hnn | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2001-12-07 | GLU | A:237 | A:237 | 112.0 | 0.589 | H | -65.4 | -43.3 | 112.0 | 0.589 | 0.0 |
HOH |
2.724 |
OE2 |
O |
||
GLU | B:237 | B:737 | 151.0 | 0.795 | H | -60.5 | -46.4 | NA | NA | NA | |||||||||||||
1n7i | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | GLU | A:237 | A:237 | 104.0 | 0.547 | H | -71.5 | -29.1 | 104.0 | 0.547 | 0.0 |
HOH |
9.264 |
OE1 |
O |
||
GLU | B:237 | B:737 | 147.0 | 0.774 | H | -51.8 | -53.6 | NA | NA | NA | |||||||||||||
1n7j | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | GLU | A:237 | A:237 | 109.0 | 0.574 | H | -77.3 | -39.2 | 109.0 | 0.574 | 0.0 |
HOH |
2.532 |
OE2 |
O |
||
GLU | B:237 | B:737 | 63.0 | NA | H | -62.1 | -43.7 | NA | NA | NA | |||||||||||||
6ws1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2020-08-05 | GLU | A:249 | A:237 | 151.0 | 0.795 | H | -72.2 | -39.0 | 151.0 | 0.795 | 0.0 |
HOH |
6.301 |
O |
O |
||
GLU | B:249 | B:237 | 114.0 | 0.6 | H | -75.8 | -37.6 | 114.0 | 0.6 | 0.0 | |||||||||||||
1yz3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-02-07 | GLU | A:237 | A:237 | 118.0 | 0.621 | H | -54.8 | -50.0 | 16.0 | 0.084 | 0.537 |
B:P11086:0.537 |
HOH |
3.449 |
N |
O |
|
GLU | B:237 | B:237 | 157.0 | 0.826 | H | -49.0 | -45.9 | 55.0 | 0.289 | 0.537 |
A:P11086:0.537 |
HOH |
3.005 |
O |
O |
||||||||
2an3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | GLU | A:237 | A:237 | 104.0 | 0.547 | H | -65.3 | -43.2 | 104.0 | 0.547 | 0.0 |
HOH |
5.028 |
O |
O |
||
GLU | B:237 | B:737 | 153.0 | 0.805 | H | -55.6 | -47.6 | NA | NA | NA | |||||||||||||
2an4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | GLU | A:237 | A:237 | 94.0 | 0.495 | H | -60.0 | -41.2 | 94.0 | 0.495 | 0.0 |
HOH |
3.573 |
N |
O |
||
GLU | B:237 | B:237 | 155.0 | 0.816 | H | -55.6 | -44.1 | NA | NA | NA | |||||||||||||
2an5 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | GLU | A:237 | A:237 | 137.0 | 0.721 | H | -59.5 | -43.9 | 137.0 | 0.721 | 0.0 |
HOH |
3.011 |
OE2 |
O |
||
GLU | B:237 | B:237 | 152.0 | 0.8 | H | -52.9 | -49.3 | NA | NA | NA | |||||||||||||
2g70 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | GLU | A:237 | A:237 | 110.0 | 0.579 | H | -60.8 | -40.6 | 110.0 | 0.579 | 0.0 |
HNT HOH |
7.146 3.021 |
N N |
O22 O |
||
GLU | B:237 | B:237 | 144.0 | 0.758 | H | -57.0 | -39.1 | NA | NA | NA | |||||||||||||
2g71 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | GLU | A:237 | A:237 | 98.0 | 0.516 | H | -63.3 | -41.1 | 98.0 | 0.516 | 0.0 |
HOH |
3.491 |
CG |
O |
||
GLU | B:237 | B:237 | 156.0 | 0.821 | H | -58.4 | -44.6 | NA | NA | NA | |||||||||||||
2g72 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | GLU | A:237 | A:237 | 98.0 | 0.516 | H | -62.6 | -47.6 | 98.0 | 0.516 | 0.0 |
HOH |
2.750 |
OE1 |
O |
||
GLU | B:237 | B:237 | 155.0 | 0.816 | H | -59.1 | -46.2 | NA | NA | NA | |||||||||||||
2g8n | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-09-12 | GLU | A:237 | A:237 | 123.0 | 0.647 | H | -59.7 | -43.6 | 123.0 | 0.647 | 0.0 |
HOH |
2.484 |
OE2 |
O |
||
GLU | B:237 | B:237 | 156.0 | 0.821 | H | -56.3 | -46.0 | NA | NA | NA | |||||||||||||
2ony | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-10-09 | GLU | A:237 | A:237 | 93.0 | 0.489 | H | -65.2 | -40.2 | 93.0 | 0.489 | 0.0 |
HOH |
4.287 |
CG |
O |
||
GLU | B:237 | B:737 | 153.0 | 0.805 | H | -59.2 | -43.3 | NA | NA | NA | |||||||||||||
3hcb | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | GLU | A:237 | A:237 | 93.0 | 0.489 | H | -66.1 | -39.0 | 93.0 | 0.489 | 0.0 | ||||||
GLU | B:237 | B:237 | 156.0 | 0.821 | H | -50.6 | -51.5 | NA | NA | NA | |||||||||||||
3hcc | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | GLU | A:237 | A:237 | 94.0 | 0.495 | H | -65.7 | -43.6 | 94.0 | 0.495 | 0.0 |
HOH |
6.308 |
O |
O |
||
GLU | B:237 | B:237 | 159.0 | 0.837 | H | -54.2 | -46.2 | NA | NA | NA | |||||||||||||
3hcd | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | GLU | A:237 | A:237 | 101.0 | 0.532 | H | -69.2 | -38.8 | 101.0 | 0.532 | 0.0 |
HOH |
5.138 |
N |
O |
||
GLU | B:237 | B:237 | 102.0 | 0.537 | H | -65.2 | -43.1 | NA | NA | NA | |||||||||||||
3hcf | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | GLU | A:237 | A:237 | 95.0 | 0.5 | H | -61.1 | -46.2 | 95.0 | 0.5 | 0.0 | ||||||
GLU | B:237 | B:237 | 103.0 | 0.542 | H | -60.0 | -46.1 | NA | NA | NA | |||||||||||||
3kpj | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 92.0 | 0.484 | H | -67.8 | -45.6 | 92.0 | 0.484 | 0.0 |
HOH |
5.266 |
N |
O |
||
GLU | B:237 | B:237 | 102.0 | 0.537 | H | -59.9 | -45.4 | 102.0 | 0.537 | 0.0 |
HOH |
4.088 |
OE1 |
O |
|||||||||
3kpu | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 83.0 | 0.437 | H | -71.0 | -31.6 | 83.0 | 0.437 | 0.0 |
HOH |
2.524 |
OE1 |
O |
||
GLU | B:237 | B:237 | 105.0 | 0.553 | H | -71.4 | -39.4 | 105.0 | 0.553 | 0.0 |
HOH |
3.433 |
CG |
O |
|||||||||
3kpv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 92.0 | 0.484 | H | -66.0 | -33.8 | 92.0 | 0.484 | 0.0 |
HOH |
2.628 |
OE1 |
O |
||
GLU | B:237 | B:237 | 105.0 | 0.553 | H | -68.9 | -40.6 | 105.0 | 0.553 | 0.0 |
HOH |
2.806 |
O |
O |
|||||||||
3kpw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 98.0 | 0.516 | H | -59.2 | -41.3 | 98.0 | 0.516 | 0.0 |
HOH |
2.447 |
OE2 |
O |
||
GLU | B:237 | B:237 | 104.0 | 0.547 | H | -73.0 | -34.4 | 104.0 | 0.547 | 0.0 |
HOH |
2.750 |
O |
O |
|||||||||
3kpy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 95.0 | 0.5 | H | -63.4 | -39.1 | 95.0 | 0.5 | 0.0 |
HOH |
2.998 |
OE2 |
O |
||
GLU | B:237 | B:237 | 102.0 | 0.537 | H | -70.2 | -37.9 | 102.0 | 0.537 | 0.0 |
HOH |
2.912 |
OE2 |
O |
|||||||||
3kqm | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 98.0 | 0.516 | H | -62.4 | -36.3 | 98.0 | 0.516 | 0.0 |
HOH |
2.800 |
OE2 |
O |
||
GLU | B:237 | B:237 | 104.0 | 0.547 | H | -71.5 | -36.9 | 104.0 | 0.547 | 0.0 |
HOH |
2.896 |
CG |
O |
|||||||||
3kqo | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 99.0 | 0.521 | H | -72.8 | -36.3 | 99.0 | 0.521 | 0.0 |
HOH |
2.575 |
OE2 |
O |
||
GLU | B:237 | B:237 | 107.0 | 0.563 | H | -67.0 | -33.1 | 107.0 | 0.563 | 0.0 |
HOH |
2.878 |
OE2 |
O |
|||||||||
3kqp | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 89.0 | 0.468 | H | -58.8 | -36.8 | 89.0 | 0.468 | 0.0 |
HOH |
2.534 |
OE1 |
O |
||
GLU | B:237 | B:237 | 101.0 | 0.532 | H | -73.7 | -37.5 | 101.0 | 0.532 | 0.0 |
HOH |
3.511 |
N |
O |
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3kqq | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 91.0 | 0.479 | H | -59.1 | -36.1 | 91.0 | 0.479 | 0.0 |
HOH |
2.886 |
CG |
O |
||
GLU | B:237 | B:237 | 102.0 | 0.537 | H | -66.5 | -35.2 | 102.0 | 0.537 | 0.0 |
HOH |
3.037 |
CB |
O |
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3kqs | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 91.0 | 0.479 | H | -62.7 | -37.5 | 91.0 | 0.479 | 0.0 |
HOH |
2.594 |
OE1 |
O |
||
GLU | B:237 | B:237 | 106.0 | 0.558 | H | -69.9 | -36.4 | 106.0 | 0.558 | 0.0 |
HOH |
2.735 |
OE2 |
O |
|||||||||
3kqt | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 89.0 | 0.468 | H | -63.3 | -39.3 | 89.0 | 0.468 | 0.0 |
HOH |
2.728 |
OE2 |
O |
||
GLU | B:237 | B:237 | 103.0 | 0.542 | H | -69.5 | -38.1 | 103.0 | 0.542 | 0.0 |
HOH |
2.946 |
OE2 |
O |
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3kqv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 92.0 | 0.484 | H | -69.3 | -32.9 | 92.0 | 0.484 | 0.0 |
HOH |
2.594 |
OE1 |
O |
||
GLU | B:237 | B:237 | 106.0 | 0.558 | H | -74.2 | -30.6 | 106.0 | 0.558 | 0.0 |
HOH |
2.780 |
O |
O |
|||||||||
3kqw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 92.0 | 0.484 | H | -62.0 | -35.6 | 92.0 | 0.484 | 0.0 |
HOH |
2.639 |
CG |
O |
||
GLU | B:237 | B:237 | 109.0 | 0.574 | H | -60.6 | -39.9 | 109.0 | 0.574 | 0.0 |
HOH |
2.731 |
O |
O |
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3kqy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 124.0 | 0.653 | H | -72.3 | -28.6 | 124.0 | 0.653 | 0.0 |
HOH |
3.440 |
N |
O |
||
GLU | B:237 | B:237 | 105.0 | 0.553 | H | -66.1 | -37.3 | 105.0 | 0.553 | 0.0 |
HOH |
4.487 |
O |
O |
|||||||||
3kr0 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 125.0 | 0.658 | H | -56.7 | -47.9 | 125.0 | 0.658 | 0.0 |
HOH |
3.399 |
N |
O |
||
GLU | B:237 | B:237 | 106.0 | 0.558 | H | -65.7 | -41.5 | 106.0 | 0.558 | 0.0 |
HOH |
2.922 |
O |
O |
|||||||||
3kr1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 87.0 | 0.458 | H | -65.2 | -39.0 | 87.0 | 0.458 | 0.0 |
HOH |
5.050 |
N |
O |
||
GLU | B:237 | B:237 | 143.0 | 0.753 | H | -61.9 | -40.1 | 143.0 | 0.753 | 0.0 |
HOH |
3.538 |
CD |
O |
|||||||||
3kr2 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | GLU | A:237 | A:237 | 96.0 | 0.505 | H | -67.1 | -36.5 | 96.0 | 0.505 | 0.0 |
HOH |
2.993 |
OE1 |
O |
||
GLU | B:237 | B:237 | 106.0 | 0.558 | H | -65.8 | -38.4 | 106.0 | 0.558 | 0.0 |
HOH |
2.836 |
O |
O |
|||||||||
4dm3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2012-04-25 | GLU | A:237 | A:237 | 103.0 | 0.542 | H | -57.3 | -42.9 | 103.0 | 0.542 | 0.0 |
HOH |
5.081 |
N |
O |
||
GLU | B:237 | B:237 | 104.0 | 0.547 | H | -66.9 | -36.5 | 104.0 | 0.547 | 0.0 |
HOH |
2.696 |
OE2 |
O |
|||||||||
4mik | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-09-10 | GLU | A:237 | A:237 | 89.0 | 0.468 | H | -70.0 | -33.3 | 89.0 | 0.468 | 0.0 |
HOH |
2.322 |
HG2 |
O |
||
GLU | B:237 | B:237 | 156.0 | 0.821 | H | -64.7 | -42.2 | 156.0 | 0.821 | 0.0 |
HOH |
2.485 |
HG3 |
O |
|||||||||
4mq4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-10-15 | GLU | A:237 | A:237 | 162.0 | 0.853 | H | -56.1 | -50.2 | 162.0 | 0.853 | 0.0 |
HOH |
2.450 |
H |
O |
||
GLU | B:237 | B:237 | 136.0 | 0.716 | H | -61.0 | -40.5 | 136.0 | 0.716 | 0.0 |
HOH |
2.659 |
H |
O |
|||||||||
3hca | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | GLU | A:237 | A:237 | 158.0 | 0.832 | H | -60.3 | -46.9 | 158.0 | 0.832 | 0.0 |
HOH |
2.930 |
OE1 |
O |
||
GLU | B:237 | B:237 | 152.0 | 0.8 | H | -52.9 | -54.5 | NA | NA | NA | |||||||||||||
3hce | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | GLU | A:237 | A:237 | 135.0 | 0.711 | H | -49.9 | -40.1 | 135.0 | 0.711 | 0.0 |
HOH |
3.321 |
CG |
O |
||
GLU | B:237 | B:237 | 131.0 | 0.689 | H | -62.5 | -38.3 | NA | NA | NA | |||||||||||||
2obf | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | GLU | A:237 | A:237 | 89.0 | 0.468 | H | -69.5 | -35.8 | 89.0 | 0.468 | 0.0 |
HOH |
2.558 |
OE1 |
O |
||
GLU | B:237 | B:737 | 111.0 | 0.584 | H | -58.8 | -32.6 | NA | NA | NA | |||||||||||||
2onz | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | GLU | A:237 | A:237 | 97.0 | 0.511 | H | -75.6 | -37.8 | 97.0 | 0.511 | 0.0 |
HOH |
4.675 |
CB |
O |
||
GLU | B:237 | B:737 | 145.0 | 0.763 | H | -60.6 | -32.1 | NA | NA | NA | |||||||||||||
2opb | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | GLU | A:237 | A:237 | 87.0 | 0.458 | H | -75.2 | -45.6 | 87.0 | 0.458 | 0.0 |
HOH |
4.276 |
CB |
O |
||
GLU | B:237 | B:237 | 101.0 | 0.532 | H | -63.4 | -31.8 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p11086-f1 | 1 | P11086 | 100.0 | 0.0 | GLU | A:237 | A:237 | 136.0 | 0.716 | H | -65.4 | -47.5 |