Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr17 | 37826544 | . | C | A | CCDS11343.1:NM_002686.4:c.751Cgg>Agg_NP_002677.1:p.251R>R | Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1hnn | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2001-12-07 | ARG | A:251 | A:251 | 72.0 | 0.32 | E | -71.6 | -40.9 | 72.0 | 0.32 | 0.0 |
HOH |
4.931 |
O |
O |
||
| ARG | B:251 | B:751 | 81.0 | 0.36 | E | -84.8 | -28.2 | NA | NA | NA | |||||||||||||
| 1n7i | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | ARG | A:251 | A:251 | 68.0 | 0.302 | E | -96.8 | -45.8 | 68.0 | 0.302 | 0.0 |
HOH |
3.724 |
O |
O |
||
| ARG | B:251 | B:751 | 81.0 | 0.36 | E | -97.0 | -21.5 | NA | NA | NA | |||||||||||||
| 1n7j | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2003-12-23 | ARG | A:251 | A:251 | 86.0 | 0.382 | E | -77.2 | -44.3 | 86.0 | 0.382 | 0.0 |
HOH |
4.947 |
O |
O |
||
| ARG | B:251 | B:751 | 83.0 | 0.369 | E | -82.1 | -25.8 | NA | NA | NA | |||||||||||||
| 6ws1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2020-08-05 | ARG | A:263 | A:251 | 95.0 | 0.422 | E | -94.5 | -11.2 | 95.0 | 0.422 | 0.0 | ||||||
| ARG | B:263 | B:251 | 111.0 | 0.493 | E | -94.7 | -32.2 | 111.0 | 0.493 | 0.0 | |||||||||||||
| 1yz3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-02-07 | ARG | A:251 | A:251 | 77.0 | 0.342 | -81.0 | -26.5 | 77.0 | 0.342 | 0.0 |
HOH |
3.942 |
O |
O |
|||
| ARG | B:251 | B:251 | 71.0 | 0.316 | E | -88.6 | -27.6 | 71.0 | 0.316 | 0.0 |
HOH |
4.316 |
O |
O |
|||||||||
| 2an3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | ARG | A:251 | A:251 | 76.0 | 0.338 | E | -78.0 | -37.9 | 76.0 | 0.338 | 0.0 |
HOH |
2.659 |
NH2 |
O |
||
| ARG | B:251 | B:751 | 72.0 | 0.32 | E | -87.9 | -32.0 | NA | NA | NA | |||||||||||||
| 2an4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | ARG | A:251 | A:251 | 81.0 | 0.36 | E | -80.1 | -35.7 | 81.0 | 0.36 | 0.0 |
PO4 HOH |
3.442 3.814 |
O O |
O3 O |
||
| ARG | B:251 | B:251 | 71.0 | 0.316 | E | -90.7 | -28.7 | NA | NA | NA | |||||||||||||
| 2an5 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-03-14 | ARG | A:251 | A:251 | 97.0 | 0.431 | E | -79.1 | -33.9 | 97.0 | 0.431 | 0.0 |
HOH |
3.969 |
O |
O |
||
| ARG | B:251 | B:251 | 75.0 | 0.333 | E | -88.8 | -34.8 | NA | NA | NA | |||||||||||||
| 2g70 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | ARG | A:251 | A:251 | 75.0 | 0.333 | E | -80.6 | -42.1 | 75.0 | 0.333 | 0.0 |
HNT HOH |
2.857 3.392 |
O NH2 |
C5 O |
||
| ARG | B:251 | B:251 | 77.0 | 0.342 | E | -96.1 | -31.2 | NA | NA | NA | |||||||||||||
| 2g71 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | ARG | A:251 | A:251 | 70.0 | 0.311 | E | -81.9 | -31.1 | 70.0 | 0.311 | 0.0 |
HOH |
3.050 |
NH2 |
O |
||
| ARG | B:251 | B:251 | 74.0 | 0.329 | E | -93.2 | -31.4 | NA | NA | NA | |||||||||||||
| 2g72 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-02-13 | ARG | A:251 | A:251 | 69.0 | 0.307 | E | -80.8 | -26.7 | 69.0 | 0.307 | 0.0 |
HOH |
6.385 |
O |
O |
||
| ARG | B:251 | B:251 | 75.0 | 0.333 | E | -87.8 | -31.9 | NA | NA | NA | |||||||||||||
| 2g8n | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2006-09-12 | ARG | A:251 | A:251 | 80.0 | 0.356 | E | -79.5 | -28.6 | 80.0 | 0.356 | 0.0 |
HOH |
6.313 |
O |
O |
||
| ARG | B:251 | B:251 | 70.0 | 0.311 | E | -86.2 | -30.9 | NA | NA | NA | |||||||||||||
| 2ony | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2007-10-09 | ARG | A:251 | A:251 | 66.0 | 0.293 | E | -81.5 | -29.5 | 66.0 | 0.293 | 0.0 |
HOH |
3.103 |
NH2 |
O |
||
| ARG | B:251 | B:751 | 68.0 | 0.302 | E | -87.6 | -31.3 | NA | NA | NA | |||||||||||||
| 3hcb | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:251 | A:251 | 76.0 | 0.338 | E | -77.3 | -38.7 | 76.0 | 0.338 | 0.0 | ||||||
| ARG | B:251 | B:251 | 79.0 | 0.351 | E | -82.3 | -39.1 | NA | NA | NA | |||||||||||||
| 3hcc | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:251 | A:251 | 78.0 | 0.347 | E | -84.3 | -36.5 | 78.0 | 0.347 | 0.0 |
HOH |
3.092 |
NE |
O |
||
| ARG | B:251 | B:251 | 77.0 | 0.342 | E | -82.2 | -33.9 | NA | NA | NA | |||||||||||||
| 3hcd | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:251 | A:251 | 75.0 | 0.333 | E | -82.1 | -27.9 | 75.0 | 0.333 | 0.0 |
HOH |
2.745 |
NH2 |
O |
||
| ARG | B:251 | B:251 | 73.0 | 0.324 | E | -87.2 | -32.2 | NA | NA | NA | |||||||||||||
| 3hcf | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:251 | A:251 | 70.0 | 0.311 | E | -86.2 | -26.4 | 70.0 | 0.311 | 0.0 |
HOH |
2.895 |
NE |
O |
||
| ARG | B:251 | B:251 | 72.0 | 0.32 | E | -90.9 | -37.2 | NA | NA | NA | |||||||||||||
| 3kpj | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 73.0 | 0.324 | E | -91.6 | -30.7 | 73.0 | 0.324 | 0.0 |
HOH |
2.483 |
NE |
O |
||
| ARG | B:251 | B:251 | 73.0 | 0.324 | E | -91.8 | -33.0 | 73.0 | 0.324 | 0.0 |
HOH |
3.043 |
NE |
O |
|||||||||
| 3kpu | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 75.0 | 0.333 | E | -80.4 | -26.6 | 75.0 | 0.333 | 0.0 |
HOH |
5.051 |
O |
O |
||
| ARG | B:251 | B:251 | 80.0 | 0.356 | E | -93.6 | -31.9 | 80.0 | 0.356 | 0.0 |
HOH |
2.585 |
NH2 |
O |
|||||||||
| 3kpv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 69.0 | 0.307 | E | -86.9 | -26.3 | 69.0 | 0.307 | 0.0 |
HOH |
2.783 |
NH2 |
O |
||
| ARG | B:251 | B:251 | 69.0 | 0.307 | E | -92.9 | -25.1 | 69.0 | 0.307 | 0.0 |
HOH |
5.027 |
O |
O |
|||||||||
| 3kpw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 73.0 | 0.324 | E | -83.0 | -32.8 | 73.0 | 0.324 | 0.0 |
HOH |
4.037 |
O |
O |
||
| ARG | B:251 | B:251 | 76.0 | 0.338 | E | -88.6 | -32.3 | 76.0 | 0.338 | 0.0 |
HOH |
2.891 |
NH2 |
O |
|||||||||
| 3kpy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 66.0 | 0.293 | E | -82.3 | -30.2 | 66.0 | 0.293 | 0.0 |
HOH |
3.844 |
O |
O |
||
| ARG | B:251 | B:251 | 70.0 | 0.311 | E | -92.8 | -29.0 | 70.0 | 0.311 | 0.0 |
HOH |
5.227 |
O |
O |
|||||||||
| 3kqm | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 68.0 | 0.302 | E | -77.7 | -33.9 | 68.0 | 0.302 | 0.0 |
HOH |
6.302 |
O |
O |
||
| ARG | B:251 | B:251 | 71.0 | 0.316 | E | -89.0 | -33.1 | 71.0 | 0.316 | 0.0 |
HOH |
5.594 |
N |
O |
|||||||||
| 3kqo | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 64.0 | 0.284 | E | -80.0 | -31.3 | 64.0 | 0.284 | 0.0 |
HOH |
5.384 |
N |
O |
||
| ARG | B:251 | B:251 | 75.0 | 0.333 | E | -91.6 | -26.5 | 75.0 | 0.333 | 0.0 |
HOH |
2.777 |
NE |
O |
|||||||||
| 3kqp | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 72.0 | 0.32 | E | -80.3 | -27.3 | 72.0 | 0.32 | 0.0 |
HOH |
3.726 |
CD |
O |
||
| ARG | B:251 | B:251 | 68.0 | 0.302 | E | -96.4 | -32.1 | 68.0 | 0.302 | 0.0 |
HOH |
4.954 |
O |
O |
|||||||||
| 3kqq | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 89.0 | 0.396 | E | -79.8 | -29.6 | 89.0 | 0.396 | 0.0 |
HOH |
5.305 |
N |
O |
||
| ARG | B:251 | B:251 | 76.0 | 0.338 | E | -87.7 | -34.8 | 76.0 | 0.338 | 0.0 |
HOH |
5.926 |
N |
O |
|||||||||
| 3kqs | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 69.0 | 0.307 | E | -82.3 | -29.9 | 69.0 | 0.307 | 0.0 |
HOH |
3.168 |
NH2 |
O |
||
| ARG | B:251 | B:251 | 72.0 | 0.32 | E | -89.4 | -28.8 | 72.0 | 0.32 | 0.0 |
HOH |
4.557 |
C |
O |
|||||||||
| 3kqt | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 69.0 | 0.307 | E | -79.6 | -30.8 | 69.0 | 0.307 | 0.0 |
HOH |
3.671 |
O |
O |
||
| ARG | B:251 | B:251 | 77.0 | 0.342 | E | -90.1 | -33.3 | 77.0 | 0.342 | 0.0 |
HOH |
4.861 |
O |
O |
|||||||||
| 3kqv | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 68.0 | 0.302 | E | -82.3 | -28.2 | 68.0 | 0.302 | 0.0 |
HOH |
3.016 |
NH2 |
O |
||
| ARG | B:251 | B:251 | 76.0 | 0.338 | E | -91.7 | -32.9 | 76.0 | 0.338 | 0.0 |
HOH |
2.912 |
NE |
O |
|||||||||
| 3kqw | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 72.0 | 0.32 | E | -78.9 | -26.1 | 72.0 | 0.32 | 0.0 |
HOH |
6.454 |
O |
O |
||
| ARG | B:251 | B:251 | 73.0 | 0.324 | E | -90.4 | -26.0 | 73.0 | 0.324 | 0.0 |
HOH |
5.133 |
O |
O |
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| 3kqy | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 72.0 | 0.32 | E | -76.5 | -44.0 | 72.0 | 0.32 | 0.0 |
HOH |
6.808 |
C |
O |
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| ARG | B:251 | B:251 | 73.0 | 0.324 | E | -85.1 | -32.8 | 73.0 | 0.324 | 0.0 |
HOH |
3.238 |
NE |
O |
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| 3kr0 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 68.0 | 0.302 | E | -81.8 | -37.5 | 68.0 | 0.302 | 0.0 |
HOH |
6.812 |
O |
O |
||
| ARG | B:251 | B:251 | 71.0 | 0.316 | E | -80.8 | -32.0 | 71.0 | 0.316 | 0.0 |
HOH |
2.916 |
NE |
O |
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| 3kr1 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 73.0 | 0.324 | E | -76.3 | -34.2 | 73.0 | 0.324 | 0.0 |
HOH |
6.709 |
NH1 |
O |
||
| ARG | B:251 | B:251 | 78.0 | 0.347 | E | -89.5 | -34.7 | 78.0 | 0.347 | 0.0 |
HOH |
4.402 |
O |
O |
|||||||||
| 3kr2 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2010-09-29 | ARG | A:251 | A:251 | 70.0 | 0.311 | E | -78.9 | -35.9 | 70.0 | 0.311 | 0.0 |
HOH |
2.908 |
NH2 |
O |
||
| ARG | B:251 | B:251 | 76.0 | 0.338 | E | -87.1 | -39.7 | 76.0 | 0.338 | 0.0 |
HOH |
3.359 |
NE |
O |
|||||||||
| 4dm3 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2012-04-25 | ARG | A:251 | A:251 | 73.0 | 0.324 | E | -93.9 | -19.3 | 73.0 | 0.324 | 0.0 |
HOH |
4.818 |
O |
O |
||
| ARG | B:251 | B:251 | 80.0 | 0.356 | E | -97.7 | -24.1 | 80.0 | 0.356 | 0.0 |
HOH |
3.108 |
NE |
O |
|||||||||
| 4mik | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-09-10 | ARG | A:251 | A:251 | 81.0 | 0.36 | E | -85.3 | -32.5 | 81.0 | 0.36 | 0.0 |
HOH |
2.327 |
HH11 |
O |
||
| ARG | B:251 | B:251 | 82.0 | 0.364 | E | -92.2 | -32.2 | 82.0 | 0.364 | 0.0 |
HOH |
2.467 |
HH11 |
O |
|||||||||
| 4mq4 | 1 | P11086 | 100.0 | 0.0 |
X-RAY |
2014-10-15 | ARG | A:251 | A:251 | 71.0 | 0.316 | E | -92.1 | -30.7 | 71.0 | 0.316 | 0.0 |
HOH |
5.816 |
N |
O |
||
| ARG | B:251 | B:251 | 88.0 | 0.391 | E | -79.3 | -27.1 | 88.0 | 0.391 | 0.0 |
HOH |
5.649 |
N |
O |
|||||||||
| 3hca | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:251 | A:251 | 69.0 | 0.307 | E | -80.4 | -31.9 | 69.0 | 0.307 | 0.0 |
HOH |
2.984 |
NE |
O |
||
| ARG | B:251 | B:251 | 70.0 | 0.311 | E | -88.0 | -32.9 | NA | NA | NA | |||||||||||||
| 3hce | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2009-08-25 | ARG | A:251 | A:251 | 71.0 | 0.316 | E | -84.9 | -35.9 | 71.0 | 0.316 | 0.0 |
HOH |
6.808 |
O |
O |
||
| ARG | B:251 | B:251 | 74.0 | 0.329 | E | -93.3 | -43.5 | NA | NA | NA | |||||||||||||
| 2obf | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | ARG | A:251 | A:251 | 69.0 | 0.307 | E | -76.2 | -27.0 | 69.0 | 0.307 | 0.0 |
HOH |
2.672 |
NH2 |
O |
||
| ARG | B:251 | B:751 | 70.0 | 0.311 | E | -86.9 | -33.0 | NA | NA | NA | |||||||||||||
| 2onz | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | ARG | A:251 | A:251 | 79.0 | 0.351 | E | -67.7 | -43.1 | 79.0 | 0.351 | 0.0 |
HOH |
6.811 |
O |
O |
||
| ARG | B:251 | B:751 | 77.0 | 0.342 | E | -80.4 | -43.3 | NA | NA | NA | |||||||||||||
| 2opb | 1 | P11086 | 99.65 | 0.0 |
X-RAY |
2007-10-09 | ARG | A:251 | A:251 | 71.0 | 0.316 | -74.2 | -51.9 | 71.0 | 0.316 | 0.0 |
HOH |
3.794 |
O |
O |
|||
| ARG | B:251 | B:251 | 72.0 | 0.32 | E | -78.3 | -29.1 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p11086-f1 | 1 | P11086 | 100.0 | 0.0 | ARG | A:251 | A:251 | 97.0 | 0.431 | E | -88.8 | -37.2 | |