Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 37826607 . G A CCDS11343.1:NM_002686.4:c.814Gtc>Atc_NP_002677.1:p.272V>I Homo sapiens phenylethanolamine N-methyltransferase (PNMT), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1hnn 1 P11086 100.0 0.0 X-RAY
 2001-12-07 VAL A:272 A:272 2.0 0.013 E -129.4 141.5 2.0 0.013 0.0 SAH
SKF
HOH
 9.276
3.858
6.869
 CG1
CG2
O
 O
O2
O
VAL B:272 B:772 3.0 0.019 E -130.8 143.8 NA NA NA
1n7i 1 P11086 100.0 0.0 X-RAY
 2003-12-23 VAL A:272 A:272 0.0 0.0 E -136.2 139.7 0.0 0.0 0.0 SAH
LY1
HOH
 9.153
4.267
9.958
 CG1
CG2
CG1
 O
CL2
O
VAL B:272 B:772 4.0 0.026 E -133.5 147.8 NA NA NA
1n7j 1 P11086 100.0 0.0 X-RAY
 2003-12-23 VAL A:272 A:272 1.0 0.006 E -134.5 143.2 1.0 0.006 0.0 SAH
IDI
HOH
 8.864
4.335
6.903
 CG1
CG2
O
 O
I
O
VAL B:272 B:772 2.0 0.013 E -131.7 148.8 NA NA NA
6ws1 1 P11086 100.0 0.0 X-RAY
 2020-08-05 VAL A:284 A:272 4.0 0.026 E -143.4 132.9 4.0 0.026 0.0 SAH
CD
K
HOH
 9.807
5.292
8.091
9.038
 CG1
CG2
CG2
CG2
 OXT
CD
K
O
VAL B:284 B:272 2.0 0.013 E -139.8 145.4 2.0 0.013 0.0 U87
 5.798
 CG2
 CL1
1yz3 1 P11086 100.0 0.0 X-RAY
 2006-02-07 VAL A:272 A:272 2.0 0.013 E -140.3 139.2 2.0 0.013 0.0 SKA
SAH
HOH
 3.910
8.926
6.363
 CG2
CG1
O
 CL4
O
O
VAL B:272 B:272 3.0 0.019 E -132.6 137.1 3.0 0.019 0.0 SKA
SAH
HOH
 3.660
9.082
6.743
 CG2
CG1
O
 CL4
O
O
2an3 1 P11086 100.0 0.0 X-RAY
 2006-03-14 VAL A:272 A:272 2.0 0.013 E -135.6 137.6 2.0 0.013 0.0 SAH
CTL
HOH
 8.999
4.088
6.393
 CG1
CG2
O
 O
C8
O
VAL B:272 B:772 2.0 0.013 E -131.1 141.0 NA NA NA
2an4 1 P11086 100.0 0.0 X-RAY
 2006-03-14 VAL A:272 A:272 2.0 0.013 E -139.1 136.6 2.0 0.013 0.0 SAH
OTR
HOH
 9.007
4.655
6.582
 CG1
CG2
O
 OXT
C3
O
VAL B:272 B:272 2.0 0.013 E -132.4 140.2 NA NA NA
2an5 1 P11086 100.0 0.0 X-RAY
 2006-03-14 VAL A:272 A:272 2.0 0.013 E -132.5 137.5 2.0 0.013 0.0 SAH
TTL
HOH
 9.104
4.291
6.800
 CG1
CG2
O
 O
CAE
O
VAL B:272 B:272 2.0 0.013 E -127.7 139.0 NA NA NA
2g70 1 P11086 100.0 0.0 X-RAY
 2007-02-13 VAL A:272 A:272 3.0 0.019 E -134.1 140.3 3.0 0.019 0.0 SAM
HNT
HOH
 8.930
4.365
6.837
 CG1
CG2
O
 O
O2
O
VAL B:272 B:272 2.0 0.013 E -123.2 136.2 NA NA NA
2g71 1 P11086 100.0 0.0 X-RAY
 2007-02-13 VAL A:272 A:272 2.0 0.013 E -131.8 142.0 2.0 0.013 0.0 SAH
FTS
HOH
 9.128
3.230
7.381
 CG1
CG2
O
 O
O1
O
VAL B:272 B:272 2.0 0.013 E -130.0 144.1 NA NA NA
2g72 1 P11086 100.0 0.0 X-RAY
 2007-02-13 VAL A:272 A:272 3.0 0.019 E -130.7 136.8 3.0 0.019 0.0 SAM
F21
HOH
 9.091
3.254
6.487
 CG1
CG2
O
 O
O2
O
VAL B:272 B:272 4.0 0.026 E -127.8 138.7 NA NA NA
2g8n 1 P11086 100.0 0.0 X-RAY
 2006-09-12 VAL A:272 A:272 3.0 0.019 E -126.3 135.0 3.0 0.019 0.0 F83
SAH
HOH
 3.765
8.931
6.310
 CG2
CG1
O
 O2
OXT
O
VAL B:272 B:272 3.0 0.019 E -126.3 135.6 NA NA NA
2ony 1 P11086 100.0 0.0 X-RAY
 2007-10-09 VAL A:272 A:272 2.0 0.013 E -128.8 142.4 2.0 0.013 0.0 SAH
TMJ
HOH
 9.197
3.892
6.986
 CG1
CG2
O
 OXT
O2
O
VAL B:272 B:772 2.0 0.013 E -128.9 140.4 NA NA NA
3hcb 1 P11086 100.0 0.0 X-RAY
 2009-08-25 VAL A:272 A:272 2.0 0.013 E -138.2 137.2 2.0 0.013 0.0 SAH
LT2
 9.322
4.502
 CG1
CG2
 O
CAL
VAL B:272 B:272 3.0 0.019 E -128.5 138.8 NA NA NA
3hcc 1 P11086 100.0 0.0 X-RAY
 2009-08-25 VAL A:272 A:272 2.0 0.013 E -129.9 137.9 2.0 0.013 0.0 LT3
SAH
HOH
 3.116
8.942
6.760
 CG2
CG1
O
 F2
OXT
O
VAL B:272 B:272 2.0 0.013 E -130.4 145.2 NA NA NA
3hcd 1 P11086 100.0 0.0 X-RAY
 2009-08-25 VAL A:272 A:272 2.0 0.013 E -132.7 138.7 2.0 0.013 0.0 SAH
LNR
HOH
 8.872
4.622
6.135
 CG1
CG2
O
 O
CAE
O
VAL B:272 B:272 2.0 0.013 E -131.1 145.4 NA NA NA
3hcf 1 P11086 100.0 0.0 X-RAY
 2009-08-25 VAL A:272 A:272 3.0 0.019 E -131.0 142.6 3.0 0.019 0.0 LT5
SAH
EDO
HOH
 2.787
8.841
8.375
8.491
 CG2
CG1
CG1
CG2
 FAC
OXT
O2
O
VAL B:272 B:272 3.0 0.019 E -144.1 149.9 NA NA NA
3kpj 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 2.0 0.013 E -130.9 136.7 2.0 0.013 0.0 SAH
PO4
HOH
 8.975
4.297
6.653
 CG1
CG2
O
 OXT
O3
O
VAL B:272 B:272 1.0 0.006 E -128.4 141.0 1.0 0.006 0.0 SAH
PO4
HOH
 9.477
4.523
6.694
 CG1
CG2
O
 O
O3
O
3kpu 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 3.0 0.019 E -128.3 137.2 3.0 0.019 0.0 SAH
ES1
HOH
 9.457
4.067
6.254
 CG1
CG2
O
 O
CAG
O
VAL B:272 B:272 3.0 0.019 E -134.0 138.2 3.0 0.019 0.0 SAH
ES1
HOH
 9.501
3.904
7.178
 CG1
CG2
O
 O
CAG
O
3kpv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 3.0 0.019 E -129.7 131.9 3.0 0.019 0.0 SAH
ADE
HOH
 9.247
5.453
4.207
 CG1
CG2
CG2
 O
N3
O
VAL B:272 B:272 3.0 0.019 E -133.6 142.0 3.0 0.019 0.0 SAH
ADE
HOH
 9.335
5.400
4.577
 CG1
CG2
CG2
 O
N3
O
3kpw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 4.0 0.026 E -130.3 138.1 4.0 0.026 0.0 SAH
1SQ
HOH
 9.115
4.438
6.277
 CG1
CG2
O
 O
C10
O
VAL B:272 B:272 1.0 0.006 E -131.6 139.5 1.0 0.006 0.0 SAH
1SQ
HOH
 9.239
4.296
7.152
 CG1
CG2
O
 O
C7
O
3kpy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 3.0 0.019 E -124.8 140.6 3.0 0.019 0.0 SAH
ES2
HOH
 9.048
4.541
6.852
 CG1
CG2
O
 O
C07
O
VAL B:272 B:272 2.0 0.013 E -131.1 141.2 2.0 0.013 0.0 SAH
ES2
HOH
 9.230
4.475
6.710
 CG1
CG2
O
 O
N09
O
3kqm 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 1.0 0.006 E -131.3 135.8 1.0 0.006 0.0 SAH
ES3
HOH
 9.271
4.001
6.568
 CG1
CG2
O
 O
BR01
O
VAL B:272 B:272 3.0 0.019 E -127.7 145.6 3.0 0.019 0.0 SAH
ES3
HOH
 9.454
3.882
6.655
 CG1
CG2
O
 O
BR01
O
3kqo 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 3.0 0.019 E -130.1 136.7 3.0 0.019 0.0 SAH
ES4
HOH
 9.268
3.975
6.855
 CG1
CG2
O
 O
CL01
O
VAL B:272 B:272 2.0 0.013 E -132.9 141.5 2.0 0.013 0.0 SAH
ES4
HOH
 9.364
3.945
6.713
 CG1
CG2
O
 O
CL01
O
3kqp 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 4.0 0.026 E -128.0 135.1 4.0 0.026 0.0 SAH
ES5
HOH
 9.387
3.825
6.309
 CG1
CG2
O
 O
C08
O
VAL B:272 B:272 2.0 0.013 E -127.8 142.0 2.0 0.013 0.0 SAH
ES5
HOH
 9.215
3.749
6.358
 CG1
CG2
O
 O
C08
O
3kqq 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 2.0 0.013 E -128.8 135.6 2.0 0.013 0.0 SAH
ES6
HOH
 9.159
3.578
6.419
 CG1
CG2
O
 O
C07
O
VAL B:272 B:272 1.0 0.006 E -130.9 134.9 1.0 0.006 0.0 SAH
ES6
HOH
 9.308
3.473
6.694
 CG1
CG2
O
 O
C06
O
3kqs 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 4.0 0.026 E -124.0 135.2 4.0 0.026 0.0 SAH
AX7
HOH
 9.185
4.444
6.198
 CG1
CG2
CG2
 O
CAC
O
VAL B:272 B:272 4.0 0.026 E -125.8 139.0 4.0 0.026 0.0 SAH
AX7
HOH
 9.368
4.161
6.186
 CG1
CG2
CG2
 O
CAC
O
3kqt 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 4.0 0.026 E -121.3 138.5 4.0 0.026 0.0 SAH
ES7
HOH
 9.133
4.282
6.876
 CG1
CG2
O
 O
C04
O
VAL B:272 B:272 3.0 0.019 E -124.8 137.1 3.0 0.019 0.0 SAH
ES7
HOH
 9.168
4.237
6.730
 CG1
CG2
O
 O
C04
O
3kqv 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 3.0 0.019 E -130.8 137.6 3.0 0.019 0.0 SAH
FAN
HOH
 9.170
4.453
6.927
 CG1
CG2
O
 O
C1
O
VAL B:272 B:272 2.0 0.013 E -129.7 139.8 2.0 0.013 0.0 SAH
FAN
HOH
 9.434
4.689
6.424
 CG1
CG2
O
 O
C5
O
3kqw 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 5.0 0.032 E -129.0 144.4 5.0 0.032 0.0 SAH
ES9
HOH
 9.232
4.417
7.447
 CG1
CG2
O
 O
CL01
O
VAL B:272 B:272 4.0 0.026 E -131.7 141.8 4.0 0.026 0.0 SAH
ES9
HOH
 9.262
4.312
6.461
 CG1
CG2
O
 O
CL01
O
3kqy 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 1.0 0.006 E -132.7 141.3 1.0 0.006 0.0 SAH
ES0
HOH
 8.948
4.228
6.874
 CG1
CG2
O
 OXT
CAD
O
VAL B:272 B:272 2.0 0.013 E -130.6 141.4 2.0 0.013 0.0 SAH
ES0
HOH
 9.209
4.083
6.572
 CG1
CG2
O
 O
CAC
O
3kr0 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 2.0 0.013 E -135.9 145.9 2.0 0.013 0.0 SAH
172
HOH
 8.973
4.027
7.846
 CG1
CG2
O
 OXT
O17
O
VAL B:272 B:272 1.0 0.006 E -144.6 141.1 1.0 0.006 0.0 SAH
172
HOH
 9.442
3.990
7.266
 CG1
CG2
N
 O
O17
O
3kr1 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 4.0 0.026 E -130.7 136.0 4.0 0.026 0.0 SAH
VGD
HOH
 8.964
4.260
7.120
 CG1
CG2
O
 OXT
CLA
O
VAL B:272 B:272 2.0 0.013 E -130.3 137.6 2.0 0.013 0.0 SAH
VGD
HOH
 9.213
4.111
6.774
 CG1
CG2
O
 O
CLA
O
3kr2 1 P11086 100.0 0.0 X-RAY
 2010-09-29 VAL A:272 A:272 2.0 0.013 E -128.8 139.4 2.0 0.013 0.0 SAH
ET2
HOH
 9.054
4.556
7.577
 CG1
CG2
O
 OXT
FAB
O
VAL B:272 B:272 2.0 0.013 E -131.5 143.0 2.0 0.013 0.0 SAH
ET2
HOH
 9.230
4.235
7.178
 CG1
CG2
O
 O
FAB
O
4dm3 1 P11086 100.0 0.0 X-RAY
 2012-04-25 VAL A:272 A:272 3.0 0.019 E -126.8 143.1 3.0 0.019 0.0 SAH
RCO
IMD
HOH
 9.164
5.751
4.046
6.710
 CG1
CG2
CG2
O
 O
O3
C5
O
VAL B:272 B:272 2.0 0.013 E -135.2 139.6 2.0 0.013 0.0 SAH
RCO
IMD
HOH
 9.174
5.915
4.033
6.702
 CG1
CG2
CG2
O
 O
O1
C4
O
4mik 1 P11086 100.0 0.0 X-RAY
 2014-09-10 VAL A:272 A:272 4.0 0.026 E -129.8 136.3 4.0 0.026 0.0 JIL
TRS
HOH
 3.455
8.192
6.201
 HG21
HG13
HG21
 O21
H31
O
VAL B:272 B:272 3.0 0.019 E -132.9 141.5 3.0 0.019 0.0 JIL
TRS
HOH
 3.653
7.382
6.163
 HG21
HG13
HG21
 O21
HO1
O
4mq4 1 P11086 100.0 0.0 X-RAY
 2014-10-15 VAL A:272 A:272 2.0 0.013 E -131.3 142.1 2.0 0.013 0.0 2D5
TRS
HOH
 3.135
7.953
6.408
 HG21
HG13
O
 H311
H12
O
VAL B:272 B:272 3.0 0.019 E -128.8 139.2 3.0 0.019 0.0 2D5
TRS
HOH
 2.930
8.457
6.260
 HG21
HG13
HG21
 H311
H21
O
3hca 1 P11086 99.65 0.0 X-RAY
 2009-08-25 VAL A:272 A:272 3.0 0.019 E -134.2 135.5 3.0 0.019 0.0 SAH
OTR
EDO
HOH
 9.016
4.633
9.232
6.790
 CG1
CG2
O
O
 OXT
C5
C1
O
VAL B:272 B:272 2.0 0.013 E -134.8 138.5 NA NA NA
3hce 1 P11086 99.65 0.0 X-RAY
 2009-08-25 VAL A:272 A:272 3.0 0.019 E -140.6 142.3 3.0 0.019 0.0 SAH
OTR
HOH
 9.223
4.639
7.318
 CG1
CG2
O
 OXT
C5
O
VAL B:272 B:272 3.0 0.019 E -142.3 143.6 NA NA NA
2obf 1 P11086 99.65 0.0 X-RAY
 2007-10-09 VAL A:272 A:272 4.0 0.026 E -130.3 142.3 4.0 0.026 0.0 F83
SAH
HOH
 3.991
8.902
6.323
 CG2
CG1
O
 O2
OXT
O
VAL B:272 B:772 4.0 0.026 E -127.4 144.0 NA NA NA
2onz 1 P11086 99.65 0.0 X-RAY
 2007-10-09 VAL A:272 A:272 4.0 0.026 E -127.7 148.6 4.0 0.026 0.0 SAH
TMJ
HOH
 9.005
3.782
7.686
 CG1
CG2
O
 OXT
O2
O
VAL B:272 B:772 4.0 0.026 E -131.4 140.5 NA NA NA
2opb 1 P11086 99.65 0.0 X-RAY
 2007-10-09 VAL A:272 A:272 4.0 0.026 E -128.1 143.2 4.0 0.026 0.0 F21
SAH
 3.427
9.271
 CG2
CG1
 O2
OXT
VAL B:272 B:272 3.0 0.019 E -122.5 142.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p11086-f1 1 P11086 100.0 0.0 VAL A:272 A:272 4.0 0.026 E -127.6 142.4