Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr17 | 40282412 | . | G | A | CCDS11419.1:NM_004583.3:c.109Ctc>Ttc_NP_004574.2:p.37L>F | Homo sapiens RAB5C, member RAS oncogene family (RAB5C), transcript variant 1, mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 4kyi | 2 | P51148 | 98.22 | 5e-122 |
X-RAY |
2014-08-13 | LEU | B:25 | B:37 | 3.0 | 0.018 | H | -64.6 | -37.6 | 3.0 | 0.018 | 0.0 |
GNP EDO MG |
5.162 6.852 8.216 |
N N N |
O1A C1 MG |
||
| LEU | D:25 | D:37 | 8.0 | 0.047 | H | -58.0 | -54.2 | NA | NA | NA | |||||||||||||
| LEU | F:25 | F:37 | 5.0 | 0.029 | H | -66.0 | -50.9 | NA | NA | NA | |||||||||||||
| LEU | H:25 | H:37 | 3.0 | 0.018 | H | -64.2 | -47.7 | NA | NA | NA | |||||||||||||
| 4q9u | 2 | P20339 | 94.15 | 4e-121 |
X-RAY |
2014-07-23 | LEU | B:23 | B:36 | 42.0 | 0.247 | H | -58.7 | -37.8 | 42.0 | 0.247 | 0.0 | ||||||
| LEU | F:23 | F:36 | 32.0 | 0.188 | H | -76.1 | -32.0 | 32.0 | 0.188 | 0.0 | |||||||||||||
| 1huq | 1 | P35278 | 100.0 | 4e-121 |
X-RAY |
2001-02-07 | LEU | A:19 | A:37 | 3.0 | 0.018 | H | -62.9 | -44.5 | 3.0 | 0.018 | 0.0 |
MG GNP HOH |
8.000 5.156 5.751 |
N N N |
MG O1A O |
||
| 1z0d | 1 | P35278 | 99.39 | 7e-121 |
X-RAY |
2005-07-26 | LEU | A:21 | A:37 | 3.0 | 0.018 | H | -64.7 | -45.2 | 3.0 | 0.018 | 0.0 |
MG GDP HOH |
8.292 5.162 4.458 |
N N N |
MG O1A O |
||
| LEU | B:21 | C:37 | 3.0 | 0.018 | H | -62.8 | -41.7 | NA | NA | NA | |||||||||||||
| 1tu3 | 1 | P20339 | 94.71 | 8e-121 |
X-RAY |
2004-10-05 | LEU | A:23 | A:36 | 7.0 | 0.041 | H | -43.9 | -47.2 | 7.0 | 0.041 | 0.0 |
MG GNP HOH |
8.038 5.167 5.859 |
N N N |
MG N7 O |
||
| LEU | B:23 | B:36 | 0.0 | 0.0 | H | -57.7 | -39.8 | 0.0 | 0.0 | 0.0 |
MG GNP HOH |
7.932 5.041 7.397 |
N N N |
MG O1A O |
|||||||||
| LEU | C:23 | C:36 | 2.0 | 0.012 | H | -56.0 | -46.5 | NA | NA | NA | |||||||||||||
| LEU | D:23 | D:36 | 2.0 | 0.012 | H | -57.9 | -29.4 | NA | NA | NA | |||||||||||||
| LEU | E:23 | E:36 | 4.0 | 0.024 | H | -56.4 | -46.6 | NA | NA | NA | |||||||||||||
| 1tu4 | 1 | P20339 | 94.71 | 8e-121 |
X-RAY |
2004-10-05 | LEU | A:23 | A:36 | 6.0 | 0.035 | H | -66.4 | -47.0 | 6.0 | 0.035 | 0.0 |
CO GDP HOH |
8.004 5.059 4.749 |
N N N |
CO O2A O |
||
| LEU | B:23 | B:36 | 4.0 | 0.024 | H | -60.5 | -45.4 | NA | NA | NA | |||||||||||||
| LEU | C:23 | C:36 | 6.0 | 0.035 | H | -62.9 | -49.6 | NA | NA | NA | |||||||||||||
| LEU | D:23 | D:36 | 0.0 | 0.0 | H | -54.6 | -55.2 | NA | NA | NA | |||||||||||||
| 1n6h | 1 | P20339 | 94.71 | 8e-121 |
X-RAY |
2002-11-27 | LEU | A:22 | A:36 | 2.0 | 0.012 | H | -62.3 | -45.8 | 2.0 | 0.012 | 0.0 |
MG GNP HOH |
8.044 5.099 5.742 |
N N N |
MG O1A O |
||
| 1r2q | 1 | P20339 | 94.71 | 8e-121 |
X-RAY |
2003-12-23 | LEU | A:22 | A:36 | 3.0 | 0.018 | H | -60.5 | -46.8 | 3.0 | 0.018 | 0.0 |
HOH |
4.548 |
N |
O |
||
| 2hei | 1 | P61020 | 89.89 | 4e-120 |
X-RAY |
2006-07-04 | LEU | A:24 | A:36 | 6.0 | 0.035 | H | -66.1 | -44.2 | 6.0 | 0.035 | 0.0 |
GDP HOH |
4.981 4.840 |
N N |
O1A O |
||
| LEU | B:24 | B:36 | 4.0 | 0.024 | H | -65.8 | -44.5 | 4.0 | 0.024 | 0.0 |
GDP HOH |
5.010 4.755 |
N N |
O1A O |
|||||||||
| 1n6p | 1 | P20339 | 94.12 | 4e-120 |
X-RAY |
2002-11-27 | LEU | A:22 | A:36 | 4.0 | 0.024 | H | -62.9 | -47.2 | 4.0 | 0.024 | 0.0 |
MG GNP HOH |
8.033 5.100 5.738 |
N N N |
MG O1A O |
||
| 1n6o | 1 | P20339 | 94.12 | 4e-120 |
X-RAY |
2002-11-27 | LEU | A:22 | A:36 | 3.0 | 0.018 | H | -60.1 | -49.4 | 3.0 | 0.018 | 0.0 |
MG GNP HOH |
8.014 5.111 5.606 |
N N N |
MG O1A O |
||
| 1n6r | 1 | P20339 | 94.12 | 5e-120 |
X-RAY |
2002-11-27 | LEU | A:22 | A:36 | 4.0 | 0.024 | H | -60.5 | -45.8 | 4.0 | 0.024 | 0.0 |
MG GNP HOH |
8.073 5.061 5.800 |
N N N |
MG O1A O |
||
| 1n6n | 1 | P20339 | 94.12 | 6e-120 |
X-RAY |
2002-11-27 | LEU | A:22 | A:36 | 3.0 | 0.018 | H | -60.6 | -46.0 | 3.0 | 0.018 | 0.0 |
MG GNP HOH |
8.028 5.091 5.739 |
N N N |
MG O1A O |
||
| 1z07 | 1 | P35278 | 99.39 | 6e-120 |
X-RAY |
2005-07-26 | LEU | A:21 | A:37 | 6.0 | 0.035 | H | -64.8 | -48.3 | 6.0 | 0.035 | 0.0 |
MG GNP HOH |
8.169 5.239 5.697 |
N N N |
MG O1A O |
||
| 1n6i | 1 | P20339 | 94.12 | 9e-120 |
X-RAY |
2002-11-27 | LEU | A:22 | A:36 | 0.0 | 0.0 | H | -59.7 | -47.6 | 0.0 | 0.0 | 0.0 |
MG GDP HOH |
8.008 5.085 4.553 |
N N N |
MG O1A O |
||
| 1n6k | 1 | P20339 | 94.12 | 9e-120 |
X-RAY |
2002-11-27 | LEU | A:22 | A:36 | 2.0 | 0.012 | H | -62.0 | -43.3 | 2.0 | 0.012 | 0.0 |
MG GDP AF3 HOH |
8.072 5.108 9.780 4.617 |
N N N N |
MG O2A F2 O |
||
| 1n6l | 1 | P20339 | 94.12 | 9e-120 |
X-RAY |
2002-11-27 | LEU | A:22 | A:36 | 2.0 | 0.012 | H | -62.1 | -44.5 | 2.0 | 0.012 | 0.0 |
MG GTP HOH |
8.070 5.132 5.757 |
N N N |
MG O1A O |
||
| 3mjh | 1 | P20339 | 94.05 | 5e-118 |
X-RAY |
2010-05-05 | LEU | A:21 | A:36 | 0.0 | 0.0 | H | -55.2 | -49.8 | 0.0 | 0.0 | 0.0 |
GTP MG HOH |
5.131 8.151 5.682 |
N N N |
O1A MG O |
||
| LEU | C:21 | C:36 | 4.0 | 0.024 | H | -55.4 | -44.6 | NA | NA | NA | |||||||||||||
| 7bl1 | 6 | P20339 | 92.86 | 8e-116 |
EM |
2021-03-03 | LEU | F:21 | DDD:36 | 0.0 | 0.0 | H | -55.4 | -50.5 | 0.0 | 0.0 | 0.0 |
GTP MG |
5.216 8.250 |
N N |
O1A MG |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p51148-f1 | 1 | P51148 | 100.0 | 3e-164 | LEU | A:37 | A:37 | 4.0 | 0.024 | H | -63.6 | -46.7 | |
| af-p20339-f1 | 1 | P20339 | 87.04 | 2e-140 | LEU | A:36 | A:36 | 4.0 | 0.024 | H | -63.5 | -45.8 | |
| af-p61020-f1 | 1 | P61020 | 86.12 | 8e-137 | LEU | A:36 | A:36 | 1.0 | 0.006 | H | -63.3 | -46.3 | |