Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 45730171 . G A CCDS11513.1:NM_002265.5:c.211Gat>Aat_NP_002256.2:p.71D>N Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2p8q 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 ASP A:71 A:71 74.0 0.493 H -71.8 -42.5 74.0 0.493 0.0 HOH
 8.553
 C
 O
2q5d 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 ASP A:71 A:71 85.0 0.567 H -69.8 -32.3 85.0 0.567 0.0
ASP C:71 B:71 121.0 0.807 S -76.5 -63.1 NA NA NA
3lww 1 Q14974 100.0 0.0 X-RAY
 2010-06-02 ASP A:71 A:71 46.0 0.307 H -55.1 -57.9 46.0 0.307 0.0
ASP C:71 C:71 15.0 0.1 H -69.1 -69.7 NA NA NA
3w5k 1 Q14974 100.0 0.0 X-RAY
 2014-03-05 ASP A:71 A:71 116.0 0.773 H -84.5 -39.8 116.0 0.773 0.0
6n88 2 Q14974 100.0 0.0 EM
 2019-02-27 ASP B:71 B:71 78.0 NA H -65.7 -40.0 78.0 NA NA
6n89 1 Q14974 100.0 0.0 EM
 2019-02-27 ASP A:71 A:71 64.0 NA H -53.5 -55.7 64.0 NA NA
1qgk 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 ASP A:71 A:71 89.0 0.593 H -75.1 -38.1 89.0 0.593 0.0
1qgr 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 ASP A:71 A:71 73.0 0.487 H -69.3 -42.9 73.0 0.487 0.0 HOH
 4.593
 O
 O
1ukl 1 P70168 99.2 0.0 X-RAY
 2003-12-09 ASP A:71 A:71 118.0 0.787 T -113.4 -56.0 118.0 0.787 0.0
ASP B:71 B:71 132.0 0.88 T -109.5 -63.2 NA NA NA
1m5n 1 Q14974 100.0 0.0 X-RAY
 2003-01-21 ASP A:71 S:71 102.0 0.68 T -79.7 -89.1 102.0 0.68 0.0 HOH
 2.902
 OD1
 O
1ibr 2 Q14974 100.0 0.0 X-RAY
 1999-06-03 ASP B:71 B:71 110.0 0.733 H -81.1 -44.3 110.0 0.733 0.0 HOH
 4.109
 O
 O
ASP D:71 D:71 111.0 0.74 H -82.4 -44.8 NA NA NA
1gcj 1 P70168 98.67 0.0 X-RAY
 2000-10-18 ASP A:77 A:71 120.0 0.8 H -76.8 -45.3 120.0 0.8 0.0 HOH
 6.802
 N
 O
ASP B:77 B:71 126.0 0.84 H -76.8 -44.6 126.0 0.84 0.0 HOH
 3.140
 O
 O
1f59 1 Q14974 99.77 0.0 X-RAY
 2000-08-16 ASP A:71 A:71 122.0 0.813 H -67.6 -43.1 122.0 0.813 0.0
ASP B:71 B:71 123.0 0.82 H -67.9 -42.2 NA NA NA
1o6o 1 Q14974 99.77 0.0 X-RAY
 2003-10-17 ASP A:71 A:71 118.0 0.787 H -66.1 -51.2 118.0 0.787 0.0
ASP B:71 B:71 119.0 0.793 H -64.2 -51.6 NA NA NA
ASP C:71 C:71 119.0 0.793 H -65.5 -49.1 NA NA NA
1o6p 1 Q14974 99.77 0.0 X-RAY
 2003-04-24 ASP A:71 A:71 121.0 0.807 H -66.5 -52.9 121.0 0.807 0.0
ASP B:71 B:71 121.0 0.807 H -64.4 -55.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14974-f1 1 Q14974 100.0 0.0 ASP A:71 A:71 107.0 0.713 H -69.9 -44.2