Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 45730196 . G A CCDS11513.1:NM_002265.5:c.236aGg>aAg_NP_002256.2:p.79R>K Homo sapiens karyopherin subunit beta 1 (KPNB1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2p8q 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 ARG A:79 A:79 94.0 0.418 H -66.0 -33.2 94.0 0.418 0.0 HOH
 2.615
 O
 O
2q5d 1 Q14974 100.0 0.0 X-RAY
 2008-01-22 ARG A:79 A:79 96.0 0.427 H -68.7 -31.2 96.0 0.427 0.0
ARG C:79 B:79 87.0 0.387 H -42.3 -45.0 NA NA NA
3lww 1 Q14974 100.0 0.0 X-RAY
 2010-06-02 ARG A:79 A:79 105.0 0.467 H -67.6 -33.4 105.0 0.467 0.0
ARG C:79 C:79 76.0 0.338 H -58.9 -47.8 NA NA NA
3w5k 1 Q14974 100.0 0.0 X-RAY
 2014-03-05 ARG A:79 A:79 88.0 0.391 H -70.5 -27.9 88.0 0.391 0.0
6n88 2 Q14974 100.0 0.0 EM
 2019-02-27 ARG B:79 B:79 22.0 NA H -63.2 -46.2 22.0 NA NA
6n89 1 Q14974 100.0 0.0 EM
 2019-02-27 ARG A:79 A:79 50.0 NA H -67.0 -34.1 50.0 NA NA
1qgk 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 ARG A:79 A:79 95.0 0.422 H -59.7 -38.9 95.0 0.422 0.0 HOH
 2.950
 NE
 O
1qgr 1 Q14974 99.77 0.0 X-RAY
 1999-05-24 ARG A:79 A:79 105.0 0.467 H -65.8 -36.6 105.0 0.467 0.0 HOH
 2.854
 NE
 O
1ukl 1 P70168 99.2 0.0 X-RAY
 2003-12-09 ARG A:79 A:79 118.0 0.524 H -50.2 -26.6 118.0 0.524 0.0
ARG B:79 B:79 145.0 0.644 H -72.0 -26.0 NA NA NA
1m5n 1 Q14974 100.0 0.0 X-RAY
 2003-01-21 ARG A:79 S:79 63.0 0.28 H -49.7 -76.0 63.0 0.28 0.0 HOH
 5.667
 N
 O
1ibr 2 Q14974 100.0 0.0 X-RAY
 1999-06-03 ARG B:79 B:79 90.0 0.4 H -58.7 -39.2 90.0 0.4 0.0 HOH
 2.619
 O
 O
ARG D:79 D:79 94.0 0.418 H -58.8 -38.8 NA NA NA
1gcj 1 P70168 98.67 0.0 X-RAY
 2000-10-18 ARG A:85 A:79 97.0 0.431 H -63.8 -35.9 97.0 0.431 0.0 HOH
 2.717
 NE
 O
ARG B:85 B:79 100.0 0.444 H -66.0 -33.3 100.0 0.444 0.0 HOH
 2.673
 NE
 O
1f59 1 Q14974 99.77 0.0 X-RAY
 2000-08-16 ARG A:79 A:79 78.0 0.347 H -52.1 -34.6 78.0 0.347 0.0
ARG B:79 B:79 78.0 0.347 H -52.5 -34.6 NA NA NA
1o6o 1 Q14974 99.77 0.0 X-RAY
 2003-10-17 ARG A:79 A:79 85.0 0.378 H -52.2 -39.1 85.0 0.378 0.0 HOH
 5.779
 NH2
 O
ARG B:79 B:79 82.0 0.364 H -52.8 -36.5 NA NA NA
ARG C:79 C:79 83.0 0.369 H -55.0 -37.0 NA NA NA
1o6p 1 Q14974 99.77 0.0 X-RAY
 2003-04-24 ARG A:79 A:79 80.0 0.356 H -47.4 -38.9 80.0 0.356 0.0 HOH
 6.919
 O
 O
ARG B:79 B:79 84.0 0.373 H -45.2 -37.2 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14974-f1 1 Q14974 100.0 0.0 ARG A:79 A:79 100.0 0.444 H -60.2 -40.6