Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 49233067 . C A CCDS11578.1:NM_198175.1:c.127Cgg>Agg_NP_937818.1:p.43R>R Homo sapiens NME/NM23 nucleoside diphosphate kinase 1 (NME1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3l7u 1 P15531 100.0 6e-113 X-RAY
 2010-11-10 ARG A:38 A:18 143.0 0.636 T -92.5 10.7 48.0 0.213 0.423 B:P15531:0.027
B:P15531:0.418
 HOH
 2.687
 O
 O
ARG B:38 B:18 144.0 0.64 T -91.5 9.7 49.0 0.218 0.422 C:P15531:0.413
A:P15531:0.027
 PO4
HOH
 3.609
2.732
 CA
O
 O1
O
ARG C:38 C:18 141.0 0.627 T -92.1 12.1 48.0 0.213 0.414 C:P15531:0.027
A:P15531:0.409
 PO4
HOH
 3.461
2.739
 CA
O
 O3
O
1jxv 1 P15531 100.0 6e-113 X-RAY
 2002-04-10 ARG A:18 A:18 138.0 0.613 T -93.8 8.0 48.0 0.213 0.4 D:P15531:0.022
C:P15531:0.396
 HOH
 2.795
 NH1
 O
ARG B:18 B:18 135.0 0.6 T -91.2 6.6 47.0 0.209 0.391 F:P15531:0.022
A:P15531:0.387
 HOH
 2.966
 NH1
 O
ARG C:18 C:18 135.0 0.6 T -93.0 6.9 49.0 0.218 0.382 E:P15531:0.022
B:P15531:0.378
 HOH
 2.814
 NH1
 O
ARG D:18 D:18 134.0 0.596 T -93.8 6.5 46.0 0.204 0.392 A:P15531:0.022
F:P15531:0.382
 HOH
 2.773
 NH1
 O
ARG E:18 E:18 134.0 0.596 T -93.9 8.2 47.0 0.209 0.387 C:P15531:0.022
D:P15531:0.382
 HOH
 2.733
 NH1
 O
ARG F:18 F:18 133.0 0.591 T -92.9 8.4 47.0 0.209 0.382 E:P15531:0.373
B:P15531:0.027
 HOH
 2.703
 NH1
 O
2hvd 1 P15531 100.0 6e-113 X-RAY
 2006-09-19 ARG A:18 A:18 136.0 0.604 T -88.6 12.2 44.0 0.196 0.408 A:P15531:0.022
B:P15531:0.409
 HOH
 2.729
 NH1
 O
ARG B:18 B:18 137.0 0.609 T -93.2 10.2 44.0 0.196 0.413 C:P15531:0.027
C:P15531:0.409
 HOH
 2.712
 NH1
 O
ARG C:18 C:18 139.0 0.618 T -87.6 8.7 46.0 0.204 0.414 B:P15531:0.027
A:P15531:0.409
 HOH
 3.202
 NH1
 O
4eno 1 P15531 100.0 6e-113 X-RAY
 2013-03-27 ARG A:18 A:18 128.0 0.569 T -81.2 13.1 99.0 0.44 0.129 A:P15531:0.129
 HOH
 3.581
 C
 O
ARG B:18 B:18 131.0 0.582 T -76.9 -0.2 105.0 0.467 0.115 B:P15531:0.116
 HOH
 2.784
 NE
 O
5ui4 1 P15531 100.0 7e-113 X-RAY
 2018-01-17 ARG A:25 A:18 141.0 0.627 T -89.7 -5.3 49.0 0.218 0.409 D:P15531:0.027
B:P15531:0.404
 HOH
 2.637
 NH1
 O
ARG B:25 B:18 142.0 0.631 T -89.7 -5.4 48.0 0.213 0.418 F:P15531:0.027
C:P15531:0.413
 HOH
 2.601
 NH1
 O
ARG C:25 C:18 142.0 0.631 T -88.8 -6.1 49.0 0.218 0.413 A:P15531:0.409
E:P15531:0.022
 HOH
 2.664
 NH1
 O
ARG D:25 D:18 142.0 0.631 T -90.0 -5.3 49.0 0.218 0.413 A:P15531:0.022
E:P15531:0.409
 HOH
 2.582
 NH1
 O
ARG E:25 E:18 141.0 0.627 T -89.8 -5.6 49.0 0.218 0.409 F:P15531:0.404
C:P15531:0.022
 HOH
 2.713
 NH1
 O
ARG F:25 F:18 143.0 0.636 T -89.7 -5.3 49.0 0.218 0.418 D:P15531:0.413
B:P15531:0.022
 HOH
 2.672
 NH1
 O
2hve 1 P15531 99.34 4e-112 X-RAY
 2006-09-19 ARG A:18 A:18 136.0 0.604 T -89.0 16.8 44.0 0.196 0.408 A:P15531:0.027
B:P15531:0.409
 HOH
 3.354
 NH2
 O
ARG B:18 B:18 137.0 0.609 T -96.6 14.0 43.0 0.191 0.418 C:P15531:0.022
C:P15531:0.413
 HOH
 2.911
 NH1
 O
ARG C:18 C:18 138.0 0.613 T -90.5 14.1 46.0 0.204 0.409 B:P15531:0.027
A:P15531:0.404
 HOH
 2.787
 NH2
 O
1ucn 1 P15531 98.68 2e-110 X-RAY
 2003-09-30 ARG A:18 A:18 139.0 0.618 T -93.9 22.3 42.0 0.187 0.431 A:P15531:0.031
B:P15531:0.418
 HOH
 2.854
 NE
 O
ARG B:18 B:18 142.0 0.631 T -91.3 13.7 46.0 0.204 0.427 C:P15531:0.031
C:P15531:0.422
 HOH
 2.770
 O
 O
ARG C:18 C:18 145.0 0.644 T -88.4 12.6 49.0 0.218 0.426 B:P15531:0.031
A:P15531:0.427
 HOH
 2.644
 NE
 O
1bhn 1 P52174 94.08 8e-108 X-RAY
 1999-02-16 ARG A:18 A:18 131.0 0.582 T -75.4 16.3 47.0 0.209 0.373 E:P52174:0.022
B:P52174:0.369
 HOH
 2.637
 NH1
 O
ARG B:18 B:18 138.0 0.613 H -81.2 4.1 51.0 0.227 0.386 C:P52174:0.373
D:P52174:0.022
 HOH
 2.602
 NE
 O
ARG C:18 C:18 133.0 0.591 T -83.9 28.1 43.0 0.191 0.4 F:P52174:0.018
A:P52174:0.396
 HOH
 2.276
 NH1
 O
ARG D:18 D:18 129.0 0.573 T -78.0 29.0 41.0 0.182 0.391 E:P52174:0.387
B:P52174:0.036
 HOH
 2.385
 NH1
 O
ARG E:18 E:18 131.0 0.582 T -106.1 49.8 41.0 0.182 0.4 F:P52174:0.396
A:P52174:0.027
 HOH
 3.783
 CB
 O
ARG F:18 F:18 134.0 0.596 T -114.3 47.9 44.0 0.196 0.4 C:P52174:0.013
D:P52174:0.396
 HOH
 3.194
 NH1
 O
1be4 1 P52175 93.38 2e-105 X-RAY
 1999-01-13 ARG A:17 A:18 128.0 0.569 T -87.7 -1.3 46.0 0.204 0.365 B:P52175:0.031
B:P52175:0.356
 HOH
 3.046
 NH1
 O
ARG B:17 B:18 133.0 0.591 H -61.4 -16.9 45.0 0.2 0.391 C:P52175:0.369
A:P52175:0.049
 HOH
 2.453
 NH1
 O
ARG C:17 C:18 139.0 0.618 H -90.4 -12.5 49.0 0.218 0.4 C:P52175:0.031
A:P52175:0.391
 HOH
 2.546
 NH1
 O
1nsk 1 P22392 88.16 4e-100 X-RAY
 1995-10-15 ARG A:18 R:18 139.0 0.618 T -88.7 9.0 44.0 0.196 0.422 C:P22392:0.422
B:P22392:0.031
ARG B:18 L:18 138.0 0.613 T -88.9 8.3 45.0 0.2 0.413 A:P22392:0.036
E:P22392:0.409
ARG C:18 T:18 139.0 0.618 T -86.3 11.1 46.0 0.204 0.414 D:P22392:0.409
F:P22392:0.031
ARG D:18 U:18 141.0 0.627 T -91.2 7.4 46.0 0.204 0.423 A:P22392:0.422
E:P22392:0.031
ARG E:18 N:18 138.0 0.613 T -90.7 8.8 45.0 0.2 0.413 D:P22392:0.031
F:P22392:0.413
ARG F:18 O:18 137.0 0.609 T -87.0 10.4 43.0 0.191 0.418 C:P22392:0.031
B:P22392:0.418
7kpf 1 P22392 88.16 4e-100 X-RAY
 2022-02-02 ARG A:18 A:18 137.0 0.609 T -94.1 12.4 45.0 0.2 0.409 F:P22392:0.409
E:P22392:0.027
 HOH
 3.048
 O
 O
ARG B:18 B:18 139.0 0.618 T -94.1 12.2 46.0 0.204 0.414 D:P22392:0.027
A:P22392:0.409
 HOH
 2.027
 HH11
 O
ARG C:18 C:18 138.0 0.613 T -94.5 13.3 47.0 0.209 0.404 F:P22392:0.022
E:P22392:0.404
 HOH
 2.236
 HH11
 O
ARG D:18 D:18 138.0 0.613 T -90.6 9.9 45.0 0.2 0.413 C:P22392:0.409
B:P22392:0.027
 HOH
 1.945
 HH21
 O
ARG E:18 E:18 137.0 0.609 T -91.3 9.4 47.0 0.209 0.4 D:P22392:0.4
A:P22392:0.027
 HOH
 2.256
 HH11
 O
ARG F:18 F:18 137.0 0.609 T -92.3 8.7 47.0 0.209 0.4 C:P22392:0.022
B:P22392:0.396
 HOH
 2.210
 HH11
 O
1nue 1 P22392 88.08 4e-99 X-RAY
 1996-04-03 ARG A:17 A:18 139.0 0.618 T -90.0 9.5 46.0 0.204 0.414 D:P22392:0.031
B:P22392:0.409
 HOH
 2.842
 NH1
 O
ARG B:17 B:18 137.0 0.609 T -87.8 5.4 46.0 0.204 0.405 C:P22392:0.404
E:P22392:0.022
 HOH
 2.835
 NH2
 O
ARG C:17 C:18 139.0 0.618 T -89.4 9.3 48.0 0.213 0.405 F:P22392:0.022
A:P22392:0.4
 HOH
 2.838
 NH1
 O
ARG D:17 D:18 134.0 0.596 T -88.3 8.9 45.0 0.2 0.396 F:P22392:0.396
A:P22392:0.013
 HOH
 2.885
 NH1
 O
ARG E:17 E:18 135.0 0.6 T -89.1 10.8 46.0 0.204 0.396 D:P22392:0.391
B:P22392:0.022
 HOH
 2.828
 NH1
 O
ARG F:17 F:18 138.0 0.613 T -86.5 9.9 46.0 0.204 0.409 C:P22392:0.031
E:P22392:0.404
 HOH
 2.726
 NH1
 O
3bbb 1 P22392 88.08 4e-99 X-RAY
 2008-09-23 ARG A:17 A:18 139.0 0.618 T -93.8 8.2 46.0 0.204 0.414 D:P22392:0.027
B:P22392:0.413
 HOH
 2.681
 O
 O
ARG B:17 B:18 139.0 0.618 T -93.1 8.9 46.0 0.204 0.414 E:P22392:0.027
C:P22392:0.413
 HOH
 2.850
 NH1
 O
ARG C:17 C:18 138.0 0.613 T -91.8 7.2 45.0 0.2 0.413 F:P22392:0.027
A:P22392:0.409
 HOH
 2.862
 NE
 O
ARG D:17 D:18 136.0 0.604 T -95.5 10.2 45.0 0.2 0.404 A:P22392:0.027
F:P22392:0.404
 HOH
 2.846
 NH1
 O
ARG E:17 E:18 140.0 0.622 T -87.7 6.8 45.0 0.2 0.422 D:P22392:0.422
B:P22392:0.027
 HOH
 2.900
 NH1
 O
ARG F:17 F:18 142.0 0.631 T -94.0 10.5 46.0 0.204 0.427 C:P22392:0.031
E:P22392:0.422
 HOH
 2.777
 NE
 O
3bbf 1 P22392 88.08 4e-99 X-RAY
 2008-09-23 ARG A:17 A:18 140.0 0.622 T -90.4 6.8 47.0 0.209 0.413 D:P22392:0.013
B:P22392:0.409
 DTT
HOH
 3.627
2.794
 O
NH1
 C1
O
ARG B:17 B:18 138.0 0.613 T -83.9 4.5 46.0 0.204 0.409 C:P22392:0.4
E:P22392:0.027
 DTT
HOH
 3.504
2.886
 C
NH1
 C2
O
ARG C:17 C:18 139.0 0.618 T -88.8 3.4 47.0 0.209 0.409 F:P22392:0.027
A:P22392:0.396
 HOH
 2.951
 NH1
 O
ARG D:17 D:18 141.0 0.627 T -86.9 3.3 49.0 0.218 0.409 F:P22392:0.409
 HOH
 2.840
 NH1
 O
ARG E:17 E:18 138.0 0.613 T -90.8 9.0 48.0 0.213 0.4 D:P22392:0.387
B:P22392:0.018
 DTT
HOH
 3.528
2.916
 C
NE
 C1
O
ARG F:17 F:18 140.0 0.622 T -88.8 4.0 49.0 0.218 0.404 E:P22392:0.396
C:P22392:0.031
 DTT
HOH
 3.229
2.824
 C
NH1
 S1
O
3bbc 1 P22392 87.42 3e-98 X-RAY
 2008-09-23 ARG A:17 A:18 139.0 0.618 T -89.9 3.2 45.0 0.2 0.418 D:P22392:0.027
B:P22392:0.413
 HOH
 2.741
 NE
 O
ARG B:17 B:18 139.0 0.618 T -90.9 6.6 47.0 0.209 0.409 C:P22392:0.409
E:P22392:0.031
 HOH
 2.686
 O
 O
ARG C:17 C:18 141.0 0.627 T -88.2 8.7 44.0 0.196 0.431 F:P22392:0.022
A:P22392:0.427
 HOH
 2.719
 NE
 O
ARG D:17 D:18 139.0 0.618 T -88.0 3.2 44.0 0.196 0.422 F:P22392:0.418
A:P22392:0.027
 HOH
 2.816
 NH1
 O
ARG E:17 E:18 141.0 0.627 T -93.0 9.4 47.0 0.209 0.418 D:P22392:0.418
B:P22392:0.022
 HOH
 2.843
 NH1
 O
ARG F:17 F:18 140.0 0.622 T -96.4 10.1 46.0 0.204 0.418 C:P22392:0.018
E:P22392:0.418
 HOH
 2.856
 NH1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15531-f1 1 P15531 100.0 3e-113 ARG A:18 A:18 126.0 0.56 T -96.2 5.6
af-p22392-f1 1 P22392 88.16 2e-100 ARG A:18 A:18 128.0 0.569 T -97.5 8.0
af-o60361-f1 1 O60361 84.67 2e-84 CYS A:3 A:3 98.0 0.726 T -84.3 6.9