Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 49233085 . A C CCDS11578.1:NM_198175.1:c.145Att>Ctt_NP_937818.1:p.49I>L Homo sapiens NME/NM23 nucleoside diphosphate kinase 1 (NME1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3l7u 1 P15531 100.0 6e-113 X-RAY
 2010-11-10 ILE A:44 A:24 0.0 0.0 H -65.6 -48.6 0.0 0.0 0.0 HOH
 4.750
 N
 O
ILE B:44 B:24 0.0 0.0 H -65.5 -46.1 0.0 0.0 0.0 HOH
 5.352
 N
 O
ILE C:44 C:24 0.0 0.0 H -67.3 -44.8 0.0 0.0 0.0 HOH
 4.882
 N
 O
1jxv 1 P15531 100.0 6e-113 X-RAY
 2002-04-10 ILE A:24 A:24 0.0 0.0 H -66.1 -46.3 0.0 0.0 0.0 HOH
 5.178
 N
 O
ILE B:24 B:24 0.0 0.0 H -66.8 -45.6 0.0 0.0 0.0 HOH
 5.297
 N
 O
ILE C:24 C:24 0.0 0.0 H -67.0 -45.8 0.0 0.0 0.0 HOH
 5.294
 N
 O
ILE D:24 D:24 0.0 0.0 H -66.5 -45.8 0.0 0.0 0.0 HOH
 5.005
 N
 O
ILE E:24 E:24 0.0 0.0 H -67.2 -44.7 0.0 0.0 0.0 HOH
 5.201
 N
 O
ILE F:24 F:24 0.0 0.0 H -65.0 -46.1 0.0 0.0 0.0 HOH
 4.753
 N
 O
2hvd 1 P15531 100.0 6e-113 X-RAY
 2006-09-19 ILE A:24 A:24 0.0 0.0 H -71.3 -45.9 0.0 0.0 0.0 HOH
 4.925
 N
 O
ILE B:24 B:24 0.0 0.0 H -65.6 -46.6 0.0 0.0 0.0 HOH
 5.185
 N
 O
ILE C:24 C:24 0.0 0.0 H -65.8 -48.9 0.0 0.0 0.0 HOH
 5.393
 N
 O
4eno 1 P15531 100.0 6e-113 X-RAY
 2013-03-27 ILE A:24 A:24 0.0 0.0 H -69.0 -51.8 0.0 0.0 0.0 HOH
 5.188
 N
 O
ILE B:24 B:24 0.0 0.0 H -56.0 -46.6 0.0 0.0 0.0 HOH
 4.708
 N
 O
5ui4 1 P15531 100.0 7e-113 X-RAY
 2018-01-17 ILE A:31 A:24 0.0 0.0 H -67.7 -50.3 0.0 0.0 0.0 HOH
 6.614
 O
 O
ILE B:31 B:24 0.0 0.0 H -68.5 -49.7 0.0 0.0 0.0 HOH
 7.926
 C
 O
ILE C:31 C:24 0.0 0.0 H -68.3 -50.0 0.0 0.0 0.0 HOH
 7.912
 C
 O
ILE D:31 D:24 0.0 0.0 H -67.8 -50.1 0.0 0.0 0.0 HOH
 4.859
 N
 O
ILE E:31 E:24 0.0 0.0 H -68.0 -49.8 0.0 0.0 0.0 HOH
 5.058
 N
 O
ILE F:31 F:24 0.0 0.0 H -67.9 -50.0 0.0 0.0 0.0 HOH
 5.162
 N
 O
2hve 1 P15531 99.34 4e-112 X-RAY
 2006-09-19 ILE A:24 A:24 0.0 0.0 H -69.0 -40.2 0.0 0.0 0.0 HOH
 7.199
 O
 O
ILE B:24 B:24 0.0 0.0 H -67.7 -44.0 0.0 0.0 0.0 HOH
 5.274
 N
 O
ILE C:24 C:24 0.0 0.0 H -68.8 -49.7 0.0 0.0 0.0 HOH
 5.137
 N
 O
1ucn 1 P15531 98.68 2e-110 X-RAY
 2003-09-30 ILE A:24 A:24 0.0 0.0 H -66.9 -48.6 0.0 0.0 0.0 HOH
 5.339
 N
 O
ILE B:24 B:24 0.0 0.0 H -69.1 -45.2 0.0 0.0 0.0 HOH
 5.157
 N
 O
ILE C:24 C:24 0.0 0.0 H -66.0 -45.8 0.0 0.0 0.0 HOH
 4.662
 N
 O
1bhn 1 P52174 94.08 8e-108 X-RAY
 1999-02-16 ILE A:24 A:24 0.0 0.0 H -63.2 -44.7 0.0 0.0 0.0 HOH
 6.556
 O
 O
ILE B:24 B:24 0.0 0.0 H -55.1 -63.4 0.0 0.0 0.0 HOH
 4.989
 N
 O
ILE C:24 C:24 0.0 0.0 H -62.0 -56.1 0.0 0.0 0.0 HOH
 5.225
 N
 O
ILE D:24 D:24 0.0 0.0 H -61.6 -46.1 0.0 0.0 0.0 HOH
 5.079
 N
 O
ILE E:24 E:24 0.0 0.0 H -64.9 -39.9 0.0 0.0 0.0 HOH
 5.280
 N
 O
ILE F:24 F:24 0.0 0.0 H -53.1 -56.3 0.0 0.0 0.0 HOH
 4.724
 N
 O
1be4 1 P52175 93.38 2e-105 X-RAY
 1999-01-13 ILE A:23 A:24 0.0 0.0 H -88.7 -36.3 0.0 0.0 0.0 HOH
 5.194
 N
 O
ILE B:23 B:24 0.0 0.0 H -64.7 -53.2 0.0 0.0 0.0 HOH
 5.584
 N
 O
ILE C:23 C:24 1.0 0.006 H -61.9 -45.2 1.0 0.006 0.0 HOH
 4.983
 N
 O
1nsk 1 P22392 88.16 4e-100 X-RAY
 1995-10-15 ILE A:24 R:24 0.0 0.0 H -67.8 -45.8 0.0 0.0 0.0
ILE B:24 L:24 0.0 0.0 H -67.3 -45.5 0.0 0.0 0.0
ILE C:24 T:24 0.0 0.0 H -60.7 -49.5 0.0 0.0 0.0
ILE D:24 U:24 0.0 0.0 H -63.1 -51.3 0.0 0.0 0.0
ILE E:24 N:24 0.0 0.0 H -63.5 -51.2 0.0 0.0 0.0
ILE F:24 O:24 0.0 0.0 H -61.3 -49.2 0.0 0.0 0.0
7kpf 1 P22392 88.16 4e-100 X-RAY
 2022-02-02 ILE A:24 A:24 0.0 0.0 H -67.2 -49.6 0.0 0.0 0.0 HOH
 4.967
 H
 O
ILE B:24 B:24 0.0 0.0 H -66.5 -50.4 0.0 0.0 0.0 HOH
 4.749
 H
 O
ILE C:24 C:24 0.0 0.0 H -66.9 -49.8 0.0 0.0 0.0 HOH
 4.836
 H
 O
ILE D:24 D:24 0.0 0.0 H -64.7 -50.2 0.0 0.0 0.0 HOH
 4.828
 H
 O
ILE E:24 E:24 1.0 0.006 H -63.6 -50.1 1.0 0.006 0.0 HOH
 5.040
 H
 O
ILE F:24 F:24 1.0 0.006 H -63.6 -50.3 1.0 0.006 0.0 HOH
 4.929
 H
 O
1nue 1 P22392 88.08 4e-99 X-RAY
 1996-04-03 ILE A:23 A:24 0.0 0.0 H -68.2 -45.7 0.0 0.0 0.0 HOH
 5.206
 N
 O
ILE B:23 B:24 0.0 0.0 H -68.7 -43.9 0.0 0.0 0.0 HOH
 5.351
 N
 O
ILE C:23 C:24 0.0 0.0 H -69.8 -48.3 0.0 0.0 0.0 HOH
 5.529
 N
 O
ILE D:23 D:24 0.0 0.0 H -69.2 -44.0 0.0 0.0 0.0 HOH
 5.345
 N
 O
ILE E:23 E:24 0.0 0.0 H -71.8 -46.2 0.0 0.0 0.0 HOH
 5.327
 N
 O
ILE F:23 F:24 0.0 0.0 H -71.1 -46.0 0.0 0.0 0.0 HOH
 5.314
 N
 O
3bbb 1 P22392 88.08 4e-99 X-RAY
 2008-09-23 ILE A:23 A:24 0.0 0.0 H -69.7 -45.0 0.0 0.0 0.0 HOH
 4.737
 N
 O
ILE B:23 B:24 0.0 0.0 H -66.1 -48.9 0.0 0.0 0.0 HOH
 4.664
 N
 O
ILE C:23 C:24 0.0 0.0 H -68.6 -46.0 0.0 0.0 0.0 HOH
 4.714
 N
 O
ILE D:23 D:24 0.0 0.0 H -66.3 -46.7 0.0 0.0 0.0 HOH
 4.728
 N
 O
ILE E:23 E:24 0.0 0.0 H -66.0 -46.5 0.0 0.0 0.0 HOH
 4.730
 N
 O
ILE F:23 F:24 0.0 0.0 H -63.0 -49.3 0.0 0.0 0.0 HOH
 4.759
 N
 O
3bbf 1 P22392 88.08 4e-99 X-RAY
 2008-09-23 ILE A:23 A:24 0.0 0.0 H -61.7 -49.1 0.0 0.0 0.0 HOH
 5.211
 N
 O
ILE B:23 B:24 0.0 0.0 H -60.5 -49.1 0.0 0.0 0.0 HOH
 5.362
 N
 O
ILE C:23 C:24 0.0 0.0 H -62.0 -53.1 0.0 0.0 0.0 HOH
 5.255
 N
 O
ILE D:23 D:24 0.0 0.0 H -68.2 -42.0 0.0 0.0 0.0 HOH
 5.276
 N
 O
ILE E:23 E:24 0.0 0.0 H -65.1 -44.4 0.0 0.0 0.0 HOH
 5.231
 N
 O
ILE F:23 F:24 0.0 0.0 H -67.6 -50.4 0.0 0.0 0.0 HOH
 5.193
 N
 O
3bbc 1 P22392 87.42 3e-98 X-RAY
 2008-09-23 ILE A:23 A:24 0.0 0.0 H -63.7 -52.0 0.0 0.0 0.0 HOH
 4.749
 N
 O
ILE B:23 B:24 0.0 0.0 H -66.4 -46.2 0.0 0.0 0.0 HOH
 4.827
 N
 O
ILE C:23 C:24 0.0 0.0 H -69.5 -49.0 0.0 0.0 0.0 HOH
 5.237
 N
 O
ILE D:23 D:24 0.0 0.0 H -68.5 -47.1 0.0 0.0 0.0 HOH
 4.817
 N
 O
ILE E:23 E:24 0.0 0.0 H -63.7 -47.3 0.0 0.0 0.0 HOH
 4.750
 N
 O
ILE F:23 F:24 0.0 0.0 H -67.1 -47.5 0.0 0.0 0.0 HOH
 5.164
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15531-f1 1 P15531 100.0 3e-113 ILE A:24 A:24 0.0 0.0 H -66.6 -51.0
af-p22392-f1 1 P22392 88.16 2e-100 ILE A:24 A:24 0.0 0.0 H -63.7 -49.0
af-o60361-f1 1 O60361 84.67 2e-84 ILE A:9 A:9 15.0 0.086 H -69.5 -51.7