Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 49237347 . G A CCDS11578.1:NM_198175.1:c.208Gaa>Aaa_NP_937818.1:p.70E>K Homo sapiens NME/NM23 nucleoside diphosphate kinase 1 (NME1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3l7u 1 P15531 100.0 6e-113 X-RAY
 2010-11-10 GLU A:65 A:45 90.0 0.474 H -60.7 -37.5 90.0 0.474 0.0 HOH
 3.022
 N
 O
GLU B:65 B:45 93.0 0.489 H -59.2 -39.6 93.0 0.489 0.0 HOH
 3.689
 N
 O
GLU C:65 C:45 106.0 0.558 H -61.0 -41.2 106.0 0.558 0.0 HOH
 3.015
 N
 O
1jxv 1 P15531 100.0 6e-113 X-RAY
 2002-04-10 GLU A:45 A:45 61.0 0.321 H -58.6 -32.4 61.0 0.321 0.0 HOH
 2.737
 CG
 O
GLU B:45 B:45 64.0 0.337 H -58.7 -31.9 64.0 0.337 0.0 HOH
 3.066
 N
 O
GLU C:45 C:45 63.0 0.332 H -57.5 -33.3 63.0 0.332 0.0 HOH
 3.685
 N
 O
GLU D:45 D:45 61.0 0.321 H -57.8 -33.3 61.0 0.321 0.0 HOH
 7.691
 N
 O
GLU E:45 E:45 64.0 0.337 H -57.1 -33.0 64.0 0.337 0.0 HOH
 7.343
 N
 O
GLU F:45 F:45 64.0 0.337 H -60.5 -31.9 64.0 0.337 0.0 HOH
 6.883
 N
 O
2hvd 1 P15531 100.0 6e-113 X-RAY
 2006-09-19 GLU A:45 A:45 102.0 0.537 H -64.2 -41.5 102.0 0.537 0.0 HOH
 3.025
 N
 O
GLU B:45 B:45 92.0 0.484 H -60.7 -40.7 92.0 0.484 0.0 HOH
 6.066
 N
 O
GLU C:45 C:45 107.0 0.563 H -53.0 -45.8 107.0 0.563 0.0 HOH
 5.818
 O
 O
4eno 1 P15531 100.0 6e-113 X-RAY
 2013-03-27 GLU A:45 A:45 84.0 0.442 H -66.2 -39.4 84.0 0.442 0.0 HOH
 3.642
 N
 O
GLU B:45 B:45 87.0 0.458 H -55.2 -39.9 87.0 0.458 0.0 HOH
 6.454
 O
 O
5ui4 1 P15531 100.0 7e-113 X-RAY
 2018-01-17 GLU A:52 A:45 87.0 0.458 H -64.5 -32.5 87.0 0.458 0.0 HOH
 7.706
 N
 O
GLU B:52 B:45 92.0 0.484 H -64.3 -32.6 92.0 0.484 0.0 HOH
 7.540
 N
 O
GLU C:52 C:45 92.0 0.484 H -63.9 -32.9 92.0 0.484 0.0 HOH
 7.488
 N
 O
GLU D:52 D:45 92.0 0.484 H -64.4 -32.6 92.0 0.484 0.0 HOH
 7.381
 N
 O
GLU E:52 E:45 93.0 0.489 H -64.3 -32.8 93.0 0.489 0.0 HOH
 6.890
 OE2
 O
GLU F:52 F:45 91.0 0.479 H -64.6 -32.7 91.0 0.479 0.0 HOH
 7.722
 N
 O
2hve 1 P15531 99.34 4e-112 X-RAY
 2006-09-19 GLU A:45 A:45 111.0 0.584 H -68.7 -38.2 111.0 0.584 0.0
GLU B:45 B:45 96.0 0.505 H -62.2 -39.9 96.0 0.505 0.0
GLU C:45 C:45 89.0 0.468 H -54.3 -37.4 89.0 0.468 0.0 HOH
 6.249
 OE2
 O
1ucn 1 P15531 98.68 2e-110 X-RAY
 2003-09-30 GLU A:45 A:45 87.0 0.458 H -56.8 -38.1 87.0 0.458 0.0 HOH
 4.506
 OE2
 O
GLU B:45 B:45 97.0 0.511 H -65.1 -34.4 97.0 0.511 0.0 HOH
 5.112
 O
 O
GLU C:45 C:45 103.0 0.542 H -58.0 -34.7 103.0 0.542 0.0 HOH
 3.530
 N
 O
1bhn 1 P52174 94.08 8e-108 X-RAY
 1999-02-16 GLU A:45 A:45 95.0 0.5 H -56.7 -35.7 95.0 0.5 0.0 HOH
 2.753
 N
 O
GLU B:45 B:45 98.0 0.516 H -70.0 -29.0 98.0 0.516 0.0 HOH
 4.150
 OE2
 O
GLU C:45 C:45 80.0 0.421 H -65.9 -42.8 80.0 0.421 0.0 HOH
 5.229
 O
 O
GLU D:45 D:45 90.0 0.474 H -75.3 -49.5 90.0 0.474 0.0 HOH
 5.892
 CD
 O
GLU E:45 E:45 85.0 0.447 H -41.0 -62.0 85.0 0.447 0.0 HOH
 4.190
 C
 O
GLU F:45 F:45 102.0 0.537 H -31.2 -49.1 102.0 0.537 0.0 HOH
 4.706
 C
 O
1be4 1 P52175 93.38 2e-105 X-RAY
 1999-01-13 GLU A:44 A:45 76.0 0.4 H -57.9 -44.5 76.0 0.4 0.0 HOH
 2.860
 N
 O
GLU B:44 B:45 110.0 0.579 H -68.3 -36.8 110.0 0.579 0.0 HOH
 3.170
 OE1
 O
GLU C:44 C:45 87.0 0.458 H -63.5 -34.3 87.0 0.458 0.0 HOH
 2.231
 N
 O
1nsk 1 P22392 88.16 4e-100 X-RAY
 1995-10-15 GLU A:45 R:45 88.0 0.463 H -54.5 -37.8 88.0 0.463 0.0
GLU B:45 L:45 89.0 0.468 H -54.3 -38.0 89.0 0.468 0.0
GLU C:45 T:45 86.0 0.453 H -60.9 -31.7 86.0 0.453 0.0
GLU D:45 U:45 87.0 0.458 H -56.4 -34.3 87.0 0.458 0.0
GLU E:45 N:45 88.0 0.463 H -56.1 -34.5 88.0 0.463 0.0
GLU F:45 O:45 89.0 0.468 H -60.2 -31.4 89.0 0.468 0.0
7kpf 1 P22392 88.16 4e-100 X-RAY
 2022-02-02 GLU A:45 A:45 69.0 0.363 H -59.1 -43.1 69.0 0.363 0.0 HOH
 7.607
 HA
 O
GLU B:45 B:45 95.0 0.5 H -58.8 -44.6 95.0 0.5 0.0 HOH
 6.385
 N
 O
GLU C:45 C:45 85.0 0.447 H -61.3 -37.7 85.0 0.447 0.0 HOH
 2.272
 H
 O
GLU D:45 D:45 19.0 0.1 H -63.2 -34.7 19.0 0.1 0.0 GOL
MG
HOH
 3.328
4.848
2.846
 CG
OE1
N
 HO2
MG
O
GLU E:45 E:45 18.0 0.095 H -62.8 -38.2 18.0 0.095 0.0 MG
HOH
 5.355
3.038
 OE2
N
 MG
O
GLU F:45 F:45 96.0 0.505 -80.9 -1.3 96.0 0.505 0.0
1nue 1 P22392 88.08 4e-99 X-RAY
 1996-04-03 GLU A:44 A:45 54.0 0.284 H -64.2 -33.0 54.0 0.284 0.0 HOH
 7.545
 N
 O
GLU B:44 B:45 55.0 0.289 H -58.9 -35.7 55.0 0.289 0.0 HOH
 6.124
 N
 O
GLU C:44 C:45 47.0 0.247 H -59.4 -41.0 47.0 0.247 0.0 HOH
 2.839
 N
 O
GLU D:44 D:45 60.0 0.316 H -59.5 -34.9 60.0 0.316 0.0 HOH
 2.563
 OE2
 O
GLU E:44 E:45 64.0 0.337 H -61.4 -41.3 64.0 0.337 0.0 HOH
 6.492
 N
 O
GLU F:44 F:45 56.0 0.295 H -63.2 -35.8 56.0 0.295 0.0 HOH
 7.546
 N
 O
3bbb 1 P22392 88.08 4e-99 X-RAY
 2008-09-23 GLU A:44 A:45 93.0 0.489 H -52.9 -45.4 93.0 0.489 0.0 HOH
 7.716
 N
 O
GLU B:44 B:45 71.0 0.374 H -56.5 -44.0 71.0 0.374 0.0 HOH
 2.992
 N
 O
GLU C:44 C:45 104.0 0.547 H -62.3 -38.3 104.0 0.547 0.0 HOH
 2.985
 N
 O
GLU D:44 D:45 94.0 0.495 H -55.3 -44.4 94.0 0.495 0.0 HOH
 4.916
 N
 O
GLU E:44 E:45 112.0 0.589 H -59.7 -41.3 112.0 0.589 0.0 HOH
 2.876
 OE1
 O
GLU F:44 F:45 59.0 0.311 H -58.1 -39.5 59.0 0.311 0.0 HOH
 2.945
 N
 O
3bbf 1 P22392 88.08 4e-99 X-RAY
 2008-09-23 GLU A:44 A:45 79.0 0.416 H -52.0 -42.5 79.0 0.416 0.0 HOH
 2.591
 OE2
 O
GLU B:44 B:45 55.0 0.289 H -52.9 -36.2 55.0 0.289 0.0 HOH
 2.468
 OE2
 O
GLU C:44 C:45 85.0 0.447 H -53.4 -37.9 85.0 0.447 0.0 HOH
 3.467
 N
 O
GLU D:44 D:45 59.0 0.311 H -52.9 -39.0 59.0 0.311 0.0 HOH
 2.463
 OE2
 O
GLU E:44 E:45 63.0 0.332 H -55.3 -43.2 63.0 0.332 0.0 HOH
 5.273
 O
 O
GLU F:44 F:45 82.0 0.432 H -59.4 -38.6 82.0 0.432 0.0 HOH
 2.911
 N
 O
3bbc 1 P22392 87.42 3e-98 X-RAY
 2008-09-23 GLU A:44 A:45 97.0 0.511 H -55.4 -39.4 97.0 0.511 0.0 HOH
 2.521
 OE2
 O
GLU B:44 B:45 102.0 0.537 H -61.0 -42.0 102.0 0.537 0.0 HOH
 2.370
 OE2
 O
GLU C:44 C:45 95.0 0.5 H -49.7 -42.3 95.0 0.5 0.0 HOH
 4.321
 OE2
 O
GLU D:44 D:45 67.0 0.353 H -52.9 -39.9 67.0 0.353 0.0 HOH
 2.886
 N
 O
GLU E:44 E:45 89.0 0.468 H -54.7 -37.5 89.0 0.468 0.0 HOH
 2.380
 OE2
 O
GLU F:44 F:45 107.0 0.563 H -54.0 -43.6 107.0 0.563 0.0 HOH
 2.530
 OE2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15531-f1 1 P15531 100.0 3e-113 GLU A:45 A:45 81.0 0.426 H -59.1 -35.1
af-p22392-f1 1 P22392 88.16 2e-100 GLU A:45 A:45 95.0 0.5 H -57.9 -38.6
af-o60361-f1 1 O60361 84.67 2e-84 GLU A:30 A:30 95.0 0.5 H -60.5 -41.5