Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 49237429 . C A CCDS11578.1:NM_198175.1:c.290cCg>cAg_NP_937818.1:p.97P>Q Homo sapiens NME/NM23 nucleoside diphosphate kinase 1 (NME1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3l7u 1 P15531 100.0 6e-113 X-RAY
 2010-11-10 PRO A:92 A:72 43.0 0.297 -72.2 151.6 2.0 0.014 0.283 B:P15531:0.283
 HOH
 3.439
 CD
 O
PRO B:92 B:72 43.0 0.297 -71.5 155.0 3.0 0.021 0.276 A:P15531:0.276
 HOH
 4.076
 CA
 O
PRO C:92 C:72 39.0 0.269 -65.6 151.0 3.0 0.021 0.248 C:P15531:0.248
 HOH
 3.172
 O
 O
1jxv 1 P15531 100.0 6e-113 X-RAY
 2002-04-10 PRO A:72 A:72 37.0 0.255 -77.0 148.7 2.0 0.014 0.241 D:P15531:0.241
 HOH
 2.781
 CD
 O
PRO B:72 B:72 37.0 0.255 -78.8 151.3 1.0 0.007 0.248 F:P15531:0.248
 HOH
 4.253
 CA
 O
PRO C:72 C:72 37.0 0.255 -76.2 148.8 2.0 0.014 0.241 E:P15531:0.241
 HOH
 4.318
 CA
 O
PRO D:72 D:72 37.0 0.255 -77.4 149.9 2.0 0.014 0.241 A:P15531:0.241
 HOH
 3.997
 CA
 O
PRO E:72 E:72 37.0 0.255 -77.5 150.2 1.0 0.007 0.248 C:P15531:0.248
 HOH
 4.239
 CA
 O
PRO F:72 F:72 38.0 0.262 -75.3 148.8 1.0 0.007 0.255 B:P15531:0.255
 HOH
 4.651
 CA
 O
2hvd 1 P15531 100.0 6e-113 X-RAY
 2006-09-19 PRO A:72 A:72 36.0 0.248 -57.3 144.9 1.0 0.007 0.241 A:P15531:0.241
 HOH
 8.454
 O
 O
PRO B:72 B:72 31.0 0.214 -81.1 153.0 0.0 0.0 0.214 C:P15531:0.214
 HOH
 3.123
 CD
 O
PRO C:72 C:72 24.0 0.166 E -80.3 150.4 0.0 0.0 0.166 B:P15531:0.166
 HOH
 4.417
 CA
 O
4eno 1 P15531 100.0 6e-113 X-RAY
 2013-03-27 PRO A:72 A:72 50.0 0.345 -65.5 136.5 5.0 0.034 0.311 B:P15531:0.31
 HOH
 4.562
 CA
 O
PRO B:72 B:72 47.0 0.324 -73.2 150.3 6.0 0.041 0.283 A:P15531:0.283
 HOH
 2.684
 O
 O
5ui4 1 P15531 100.0 7e-113 X-RAY
 2018-01-17 PRO A:79 A:72 33.0 0.228 -78.2 158.6 1.0 0.007 0.221 D:P15531:0.221
 HOH
 4.255
 CA
 O
PRO B:79 B:72 34.0 0.234 -76.9 158.4 2.0 0.014 0.22 F:P15531:0.221
 HOH
 3.147
 CD
 O
PRO C:79 C:72 35.0 0.241 -77.5 158.5 1.0 0.007 0.234 E:P15531:0.234
 HOH
 4.334
 CA
 O
PRO D:79 D:72 34.0 0.234 -78.4 158.6 1.0 0.007 0.227 A:P15531:0.228
 HOH
 4.324
 CA
 O
PRO E:79 E:72 33.0 0.228 -79.4 159.1 1.0 0.007 0.221 C:P15531:0.221
 HOH
 4.305
 CA
 O
PRO F:79 F:72 33.0 0.228 -77.8 158.7 2.0 0.014 0.214 B:P15531:0.214
 HOH
 4.229
 CA
 O
2hve 1 P15531 99.34 4e-112 X-RAY
 2006-09-19 PRO A:72 A:72 36.0 0.248 -63.3 147.5 1.0 0.007 0.241 A:P15531:0.241
 HOH
 7.394
 CD
 O
PRO B:72 B:72 32.0 0.221 -79.3 158.3 0.0 0.0 0.221 C:P15531:0.221
 HOH
 7.336
 CG
 O
PRO C:72 C:72 33.0 0.228 -81.5 154.6 0.0 0.0 0.228 B:P15531:0.228
 HOH
 4.244
 C
 O
1ucn 1 P15531 98.68 2e-110 X-RAY
 2003-09-30 PRO A:72 A:72 43.0 0.297 -61.8 154.4 4.0 0.028 0.269 A:P15531:0.269
 HOH
 6.615
 CB
 O
PRO B:72 B:72 40.0 0.276 -72.5 153.8 3.0 0.021 0.255 C:P15531:0.255
 HOH
 2.968
 CD
 O
PRO C:72 C:72 44.0 0.303 -65.4 158.6 3.0 0.021 0.282 B:P15531:0.283
 HOH
 4.257
 CA
 O
1bhn 1 P52174 94.08 8e-108 X-RAY
 1999-02-16 PRO A:72 A:72 29.0 0.2 E -65.7 170.8 2.0 0.014 0.186 E:P52174:0.186
 HOH
 6.844
 CG
 O
PRO B:72 B:72 31.0 0.214 E -75.3 155.4 0.0 0.0 0.214 D:P52174:0.214
 HOH
 6.941
 CG
 O
PRO C:72 C:72 39.0 0.269 -71.4 149.1 2.0 0.014 0.255 F:P52174:0.255
 HOH
 5.894
 CD
 O
PRO D:72 D:72 39.0 0.269 E -76.9 172.3 3.0 0.021 0.248 B:P52174:0.248
 HOH
 6.655
 CD
 O
PRO E:72 E:72 38.0 0.262 -62.2 157.9 3.0 0.021 0.241 A:P52174:0.241
 HOH
 3.410
 CD
 O
PRO F:72 F:72 34.0 0.234 E -84.1 166.2 1.0 0.007 0.227 C:P52174:0.228
 HOH
 2.873
 CD
 O
1be4 1 P52175 93.38 2e-105 X-RAY
 1999-01-13 PRO A:71 A:72 28.0 0.193 E -94.9 163.5 0.0 0.0 0.193 B:P52175:0.193
 HOH
 2.823
 CD
 O
PRO B:71 B:72 31.0 0.214 -75.5 145.6 1.0 0.007 0.207 A:P52175:0.207
 HOH
 2.755
 O
 O
PRO C:71 C:72 35.0 0.241 -57.3 153.6 1.0 0.007 0.234 C:P52175:0.234
 HOH
 3.085
 O
 O
1nsk 1 P22392 88.16 4e-100 X-RAY
 1995-10-15 PRO A:72 R:72 30.0 0.207 -68.5 154.1 1.0 0.007 0.2 B:P22392:0.2
PRO B:72 L:72 30.0 0.207 -68.5 153.9 1.0 0.007 0.2 A:P22392:0.2
PRO C:72 T:72 30.0 0.207 -68.2 153.3 1.0 0.007 0.2 F:P22392:0.2
PRO D:72 U:72 31.0 0.214 -70.3 150.7 1.0 0.007 0.207 E:P22392:0.207
PRO E:72 N:72 30.0 0.207 -70.7 150.5 2.0 0.014 0.193 D:P22392:0.193
PRO F:72 O:72 32.0 0.221 -68.2 154.4 1.0 0.007 0.214 C:P22392:0.214
7kpf 1 P22392 88.16 4e-100 X-RAY
 2022-02-02 PRO A:72 A:72 30.0 0.207 -75.0 155.1 1.0 0.007 0.2 E:P22392:0.2
 HOH
 3.624
 HA
 O
PRO B:72 B:72 30.0 0.207 -74.5 154.3 1.0 0.007 0.2 D:P22392:0.2
 HOH
 3.291
 HA
 O
PRO C:72 C:72 29.0 0.2 -74.7 155.5 0.0 0.0 0.2 F:P22392:0.2
 HOH
 6.323
 HG2
 O
PRO D:72 D:72 39.0 0.269 E -76.8 136.2 3.0 0.021 0.248 C:P22392:0.014
B:P22392:0.241
 GOL
HOH
 6.990
6.205
 O
N
 HO1
O
PRO E:72 E:72 38.0 0.262 E -78.7 140.7 3.0 0.021 0.241 D:P22392:0.007
A:P22392:0.234
 HOH
 3.178
 HD2
 O
PRO F:72 F:72 30.0 0.207 E -80.4 156.9 0.0 0.0 0.207 C:P22392:0.207
 MG
HOH
 5.660
5.823
 HD3
HD3
 MG
O
1nue 1 P22392 88.08 4e-99 X-RAY
 1996-04-03 PRO A:71 A:72 31.0 0.214 -72.6 160.6 1.0 0.007 0.207 D:P22392:0.207
 HOH
 4.329
 CA
 O
PRO B:71 B:72 28.0 0.193 -73.5 162.4 1.0 0.007 0.186 E:P22392:0.186
 HOH
 4.281
 CA
 O
PRO C:71 C:72 29.0 0.2 -75.2 160.3 1.0 0.007 0.193 F:P22392:0.193
 HOH
 4.236
 CA
 O
PRO D:71 D:72 29.0 0.2 -71.9 160.4 1.0 0.007 0.193 A:P22392:0.193
 HOH
 4.275
 C
 O
PRO E:71 E:72 29.0 0.2 -74.6 159.0 0.0 0.0 0.2 B:P22392:0.2
 HOH
 4.308
 CA
 O
PRO F:71 F:72 28.0 0.193 -74.1 164.7 0.0 0.0 0.193 C:P22392:0.193
 HOH
 4.275
 CA
 O
3bbb 1 P22392 88.08 4e-99 X-RAY
 2008-09-23 PRO A:71 A:72 31.0 0.214 -72.6 157.4 2.0 0.014 0.2 D:P22392:0.2
 HOH
 2.971
 O
 O
PRO B:71 B:72 42.0 0.29 -70.0 154.1 3.0 0.021 0.269 E:P22392:0.269
 HOH
 2.942
 O
 O
PRO C:71 C:72 29.0 0.2 -68.1 160.4 1.0 0.007 0.193 F:P22392:0.193
 HOH
 2.894
 O
 O
PRO D:71 D:72 33.0 0.228 -71.5 156.7 2.0 0.014 0.214 A:P22392:0.214
 HOH
 2.901
 O
 O
PRO E:71 E:72 31.0 0.214 -69.4 154.7 1.0 0.007 0.207 B:P22392:0.207
 HOH
 2.932
 O
 O
PRO F:71 F:72 43.0 0.297 -72.4 155.1 4.0 0.028 0.269 C:P22392:0.269
 HOH
 2.947
 O
 O
3bbf 1 P22392 88.08 4e-99 X-RAY
 2008-09-23 PRO A:71 A:72 29.0 0.2 -66.6 154.9 1.0 0.007 0.193 D:P22392:0.193
 HOH
 2.877
 O
 O
PRO B:71 B:72 27.0 0.186 -69.1 160.5 1.0 0.007 0.179 E:P22392:0.179
 HOH
 2.971
 O
 O
PRO C:71 C:72 30.0 0.207 -67.3 157.6 0.0 0.0 0.207 F:P22392:0.207
 HOH
 2.941
 O
 O
PRO D:71 D:72 30.0 0.207 -68.6 158.9 0.0 0.0 0.207 A:P22392:0.207
 HOH
 2.883
 O
 O
PRO E:71 E:72 30.0 0.207 -63.7 154.4 1.0 0.007 0.2 B:P22392:0.2
 HOH
 2.939
 O
 O
PRO F:71 F:72 32.0 0.221 -65.6 159.5 1.0 0.007 0.214 C:P22392:0.214
 HOH
 2.998
 O
 O
3bbc 1 P22392 87.42 3e-98 X-RAY
 2008-09-23 PRO A:71 A:72 30.0 0.207 -63.3 152.2 2.0 0.014 0.193 D:P22392:0.193
 HOH
 2.870
 O
 O
PRO B:71 B:72 31.0 0.214 -70.8 155.2 1.0 0.007 0.207 E:P22392:0.207
 HOH
 2.828
 O
 O
PRO C:71 C:72 29.0 0.2 -73.4 159.8 2.0 0.014 0.186 F:P22392:0.186
 HOH
 2.955
 O
 O
PRO D:71 D:72 30.0 0.207 -71.2 149.9 1.0 0.007 0.2 A:P22392:0.2
 HOH
 3.000
 O
 O
PRO E:71 E:72 30.0 0.207 -69.5 155.5 1.0 0.007 0.2 B:P22392:0.2
 HOH
 3.007
 O
 O
PRO F:71 F:72 32.0 0.221 -70.1 149.3 1.0 0.007 0.214 C:P22392:0.214
 HOH
 2.998
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15531-f1 1 P15531 100.0 3e-113 PRO A:72 A:72 32.0 0.221 -75.3 156.3
af-p22392-f1 1 P22392 88.16 2e-100 PRO A:72 A:72 37.0 0.255 -73.5 159.0
af-o60361-f1 1 O60361 84.67 2e-84 PRO A:57 A:57 46.0 0.317 E -71.8 157.6