Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 49238632 . A C CCDS11578.1:NM_198175.1:c.415Agg>Cgg_NP_937818.1:p.139R>R Homo sapiens NME/NM23 nucleoside diphosphate kinase 1 (NME1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3l7u 1 P15531 100.0 6e-113 X-RAY
 2010-11-10 ARG A:134 A:114 122.0 0.542 G -130.5 66.6 32.0 0.142 0.4 B:P15531:0.4
 HOH
 2.819
 NH2
 O
ARG B:134 B:114 118.0 0.524 G -128.2 66.8 29.0 0.129 0.395 C:P15531:0.396
 HOH
 2.827
 O
 O
ARG C:134 C:114 126.0 0.56 G -130.7 63.9 40.0 0.178 0.382 A:P15531:0.382
 HOH
 2.789
 O
 O
1jxv 1 P15531 100.0 6e-113 X-RAY
 2002-04-10 ARG A:114 A:114 120.0 0.533 B -125.6 69.9 32.0 0.142 0.391 C:P15531:0.391
 HOH
 2.603
 O
 O
ARG B:114 B:114 120.0 0.533 B -123.3 67.2 33.0 0.147 0.386 A:P15531:0.387
 HOH
 2.577
 O
 O
ARG C:114 C:114 119.0 0.529 B -125.1 68.0 35.0 0.156 0.373 B:P15531:0.373
 HOH
 3.037
 O
 O
ARG D:114 D:114 119.0 0.529 B -127.6 66.9 35.0 0.156 0.373 F:P15531:0.373
 HOH
 2.889
 O
 O
ARG E:114 E:114 121.0 0.538 B -126.5 67.8 33.0 0.147 0.391 D:P15531:0.391
 HOH
 2.422
 O
 O
ARG F:114 F:114 120.0 0.533 B -125.0 67.9 32.0 0.142 0.391 E:P15531:0.391
 HOH
 2.604
 O
 O
2hvd 1 P15531 100.0 6e-113 X-RAY
 2006-09-19 ARG A:114 A:114 129.0 0.573 G -138.0 59.6 36.0 0.16 0.413 B:P15531:0.413
 ADP
HOH
 5.298
2.981
 N
O
 O2'
O
ARG B:114 B:114 128.0 0.569 G -139.5 62.6 36.0 0.16 0.409 C:P15531:0.409
 ADP
HOH
 5.395
2.860
 N
O
 O2'
O
ARG C:114 C:114 128.0 0.569 G -128.0 61.6 38.0 0.169 0.4 A:P15531:0.4
 ADP
HOH
 5.312
2.783
 N
O
 O2'
O
4eno 1 P15531 100.0 6e-113 X-RAY
 2013-03-27 ARG A:114 A:114 112.0 0.498 S -96.7 73.7 112.0 0.498 0.0 PO4
 7.965
 C
 O3
ARG B:114 B:114 111.0 0.493 S -72.5 109.5 111.0 0.493 0.0 PO4
HOH
 7.840
2.629
 C
NH2
 O4
O
5ui4 1 P15531 100.0 7e-113 X-RAY
 2018-01-17 ARG A:121 A:114 127.0 0.564 G -127.9 70.6 29.0 0.129 0.435 B:P15531:0.436
 A7Z
HOH
 3.904
3.066
 NH1
O
 CZ
O
ARG B:121 B:114 129.0 0.573 G -127.9 70.5 59.0 0.262 0.311 C:P15531:0.311
 A7Z
HOH
 4.081
2.939
 NH1
O
 CZ
O
ARG C:121 C:114 129.0 0.573 G -128.0 70.4 59.0 0.262 0.311 A:P15531:0.311
 A7Z
HOH
 3.876
2.796
 NH1
O
 CZ
O
ARG D:121 D:114 130.0 0.578 G -128.1 70.6 60.0 0.267 0.311 E:P15531:0.311
 A7Z
HOH
 4.340
2.729
 NH1
O
 CZ
O
ARG E:121 E:114 128.0 0.569 G -127.7 70.9 61.0 0.271 0.298 F:P15531:0.298
 A7Z
HOH
 3.866
2.737
 NH1
O
 CZ
O
ARG F:121 F:114 129.0 0.573 G -128.0 70.9 38.0 0.169 0.404 D:P15531:0.404
 A7Z
HOH
 4.200
2.669
 NH1
O
 CZ
O
2hve 1 P15531 99.34 4e-112 X-RAY
 2006-09-19 ARG A:114 A:114 129.0 0.573 G -136.9 61.8 35.0 0.156 0.417 B:P15531:0.418
 ADP
HOH
 5.791
2.836
 N
O
 O2'
O
ARG B:114 B:114 124.0 0.551 G -137.8 59.8 34.0 0.151 0.4 C:P15531:0.4
 ADP
HOH
 5.408
2.620
 N
O
 O2'
O
ARG C:114 C:114 131.0 0.582 G -124.0 62.9 32.0 0.142 0.44 A:P15531:0.44
 ADP
HOH
 5.509
2.947
 N
O
 O2'
O
1ucn 1 P15531 98.68 2e-110 X-RAY
 2003-09-30 ARG A:114 A:114 126.0 0.56 G -147.4 60.4 36.0 0.16 0.4 B:P15531:0.4
 ADP
TRS
HOH
 5.575
7.030
3.151
 N
NH2
O
 O2'
C3
O
ARG B:114 B:114 118.0 0.524 G -137.6 61.3 33.0 0.147 0.377 C:P15531:0.378
 ADP
HOH
 5.764
2.814
 N
O
 O2'
O
ARG C:114 C:114 124.0 0.551 G -128.6 66.6 33.0 0.147 0.404 A:P15531:0.404
 ADP
HOH
 5.563
2.649
 N
O
 O2'
O
1bhn 1 P52174 94.08 8e-108 X-RAY
 1999-02-16 ARG A:114 A:114 118.0 0.524 T -86.1 -6.1 23.0 0.102 0.422 B:P52174:0.422
 35G
GDP
HOH
 5.168
5.440
3.272
 NH2
NH2
O
 N2
N2
O
ARG B:114 B:114 120.0 0.533 S -103.9 70.6 26.0 0.116 0.417 C:P52174:0.418
 35G
GDP
HOH
 5.673
5.862
3.740
 N
N
C
 O2'
O2'
O
ARG C:114 C:114 116.0 0.516 G -149.3 68.2 29.0 0.129 0.387 A:P52174:0.387
 35G
GDP
HOH
 6.070
5.088
2.908
 N
N
O
 N2
O2'
O
ARG D:114 D:114 115.0 0.511 G -141.6 72.8 24.0 0.107 0.404 E:P52174:0.404
 35G
GDP
HOH
 5.517
5.180
2.483
 N
N
NH2
 O2'
O2'
O
ARG E:114 E:114 116.0 0.516 G -136.8 61.9 26.0 0.116 0.4 F:P52174:0.4
 35G
GDP
HOH
 5.754
4.994
3.055
 N
N
O
 O2'
O2'
O
ARG F:114 F:114 126.0 0.56 S -127.1 67.3 21.0 0.093 0.467 D:P52174:0.467
 35G
GDP
HOH
 5.734
5.797
3.381
 N
N
CB
 N2
O2'
O
1be4 1 P52175 93.38 2e-105 X-RAY
 1999-01-13 ARG A:113 A:114 129.0 0.573 B -141.1 72.0 31.0 0.138 0.435 B:P52175:0.436
 PCG
HOH
 5.798
2.522
 N
O
 O2'
O
ARG B:113 B:114 136.0 0.604 G -136.3 61.1 38.0 0.169 0.435 C:P52175:0.436
 PCG
HOH
 5.517
2.614
 N
O
 O2'
O
ARG C:113 C:114 133.0 0.591 S -136.5 52.7 38.0 0.169 0.422 A:P52175:0.422
 PCG
HOH
 6.068
2.658
 N
O
 O2'
O
1nsk 1 P22392 88.16 4e-100 X-RAY
 1995-10-15 ARG A:114 R:114 120.0 0.533 T -112.8 76.3 45.0 0.2 0.333 C:P22392:0.333
ARG B:114 L:114 119.0 0.529 T -112.3 75.9 44.0 0.196 0.333 E:P22392:0.333
ARG C:114 T:114 120.0 0.533 T -113.0 70.2 43.0 0.191 0.342 D:P22392:0.342
ARG D:114 U:114 119.0 0.529 T -112.1 73.7 46.0 0.204 0.325 A:P22392:0.324
ARG E:114 N:114 120.0 0.533 T -112.5 73.3 44.0 0.196 0.337 F:P22392:0.338
ARG F:114 O:114 118.0 0.524 T -112.7 70.1 46.0 0.204 0.32 B:P22392:0.32
7kpf 1 P22392 88.16 4e-100 X-RAY
 2022-02-02 ARG A:114 A:114 130.0 0.578 B -140.4 65.4 39.0 0.173 0.405 F:P22392:0.404
 WYV
HOH
 5.912
2.658
 HH12
HB2
 H2A
O
ARG B:114 B:114 114.0 0.507 B -139.4 63.8 23.0 0.102 0.405 A:P22392:0.404
 WYV
MG
HOH
 5.985
5.139
2.212
 HH12
N
HH12
 H2A
MG
O
ARG C:114 C:114 134.0 0.596 B -138.6 65.6 39.0 0.173 0.423 E:P22392:0.422
 WYV
HOH
 6.094
2.593
 N
O
 H2A
O
ARG D:114 D:114 110.0 0.489 G -136.1 60.4 31.0 0.138 0.351 C:P22392:0.351
 GOL
MG
HOH
 9.224
8.952
2.693
 HA
C
O
 HO1
MG
O
ARG E:114 E:114 110.0 0.489 G -135.8 61.4 29.0 0.129 0.36 D:P22392:0.36
 MG
HOH
 8.559
2.715
 C
HB2
 MG
O
ARG F:114 F:114 127.0 0.564 G -136.7 62.6 42.0 0.187 0.377 B:P22392:0.378
 HOH
 2.809
 HB2
 O
1nue 1 P22392 88.08 4e-99 X-RAY
 1996-04-03 ARG A:113 A:114 127.0 0.564 G -141.4 67.8 43.0 0.191 0.373 B:P22392:0.373
 GDP
HOH
 5.592
2.694
 N
O
 O2'
O
ARG B:113 B:114 126.0 0.56 G -138.3 67.5 38.0 0.169 0.391 C:P22392:0.391
 GDP
HOH
 5.558
2.755
 N
O
 O2'
O
ARG C:113 C:114 127.0 0.564 S -136.2 71.4 41.0 0.182 0.382 A:P22392:0.382
 GDP
HOH
 5.346
2.829
 N
O
 O2'
O
ARG D:113 D:114 126.0 0.56 G -136.6 70.9 36.0 0.16 0.4 F:P22392:0.4
 GDP
HOH
 5.635
2.686
 N
NH2
 O2'
O
ARG E:113 E:114 124.0 0.551 G -135.9 70.1 41.0 0.182 0.369 D:P22392:0.369
 GDP
HOH
 5.536
2.820
 N
O
 O2'
O
ARG F:113 F:114 127.0 0.564 S -135.1 74.5 43.0 0.191 0.373 E:P22392:0.373
 GDP
HOH
 5.777
2.829
 N
O
 O2'
O
3bbb 1 P22392 88.08 4e-99 X-RAY
 2008-09-23 ARG A:113 A:114 132.0 0.587 B -135.4 65.3 36.0 0.16 0.427 B:P22392:0.427
 HOH
 2.759
 O
 O
ARG B:113 B:114 128.0 0.569 G -138.8 62.8 35.0 0.156 0.413 C:P22392:0.413
 DG
HOH
 5.824
2.790
 N
O
 O6
O
ARG C:113 C:114 129.0 0.573 G -134.5 68.6 40.0 0.178 0.395 A:P22392:0.396
 DA
DG
HOH
 5.747
8.560
2.749
 N
NH1
O
 C8
O6
O
ARG D:113 D:114 131.0 0.582 G -139.4 63.1 35.0 0.156 0.426 F:P22392:0.427
 HOH
 2.699
 O
 O
ARG E:113 E:114 130.0 0.578 G -138.2 65.5 40.0 0.178 0.4 D:P22392:0.4
 DA
DG
HOH
 5.995
8.608
2.783
 N
N
O
 C8
OP1
O
ARG F:113 F:114 129.0 0.573 B -135.5 65.2 34.0 0.151 0.422 E:P22392:0.422
 DG
HOH
 5.739
2.760
 NH1
O
 N2
O
3bbf 1 P22392 88.08 4e-99 X-RAY
 2008-09-23 ARG A:113 A:114 131.0 0.582 G -134.9 70.1 39.0 0.173 0.409 B:P22392:0.409
 GDP
HOH
 5.767
2.831
 N
O
 O2'
O
ARG B:113 B:114 127.0 0.564 B -132.2 69.4 37.0 0.164 0.4 C:P22392:0.4
 GDP
HOH
 5.626
2.760
 N
O
 O2'
O
ARG C:113 C:114 132.0 0.587 -136.7 73.9 41.0 0.182 0.405 A:P22392:0.404
 GDP
HOH
 5.345
2.767
 N
O
 O2'
O
ARG D:113 D:114 133.0 0.591 G -133.0 75.2 40.0 0.178 0.413 F:P22392:0.413
 GDP
HOH
 5.784
2.735
 N
O
 O2'
O
ARG E:113 E:114 129.0 0.573 G -130.7 70.5 38.0 0.169 0.404 D:P22392:0.404
 GDP
HOH
 5.659
2.754
 N
O
 O2'
O
ARG F:113 F:114 127.0 0.564 B -138.9 71.2 36.0 0.16 0.404 E:P22392:0.404
 GDP
HOH
 5.629
2.717
 N
O
 O2'
O
3bbc 1 P22392 87.42 3e-98 X-RAY
 2008-09-23 ARG A:113 A:114 131.0 0.582 G -135.4 65.7 34.0 0.151 0.431 B:P22392:0.431
 HOH
 2.765
 O
 O
ARG B:113 B:114 125.0 0.556 G -133.9 64.5 31.0 0.138 0.418 C:P22392:0.418
 HOH
 2.743
 NH2
 O
ARG C:113 C:114 126.0 0.56 B -134.5 68.3 33.0 0.147 0.413 A:P22392:0.413
 HOH
 2.834
 O
 O
ARG D:113 D:114 119.0 0.529 G -136.3 67.9 32.0 0.142 0.387 F:P22392:0.387
 HOH
 2.760
 O
 O
ARG E:113 E:114 127.0 0.564 G -140.9 68.5 33.0 0.147 0.417 D:P22392:0.418
 HOH
 2.861
 O
 O
ARG F:113 F:114 132.0 0.587 B -142.6 67.7 40.0 0.178 0.409 E:P22392:0.409
 HOH
 2.673
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15531-f1 1 P15531 100.0 3e-113 ARG A:114 A:114 127.0 0.564 G -137.7 56.7
af-p22392-f1 1 P22392 88.16 2e-100 ARG A:114 A:114 130.0 0.578 G -136.7 51.4
af-o60361-f1 1 O60361 84.67 2e-84 ARG A:99 A:99 137.0 0.609 G -135.0 44.5