Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 49239157 . A C CCDS11578.1:NM_198175.1:c.485gAg>gCg_NP_937818.1:p.162E>A Homo sapiens NME/NM23 nucleoside diphosphate kinase 1 (NME1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3l7u 1 P15531 100.0 6e-113 X-RAY
 2010-11-10 GLU A:157 A:137 153.0 0.805 G -77.5 -8.8 153.0 0.805 0.0 HOH
 4.199
 O
 O
GLU B:157 B:137 152.0 0.8 G -71.2 -26.2 152.0 0.8 0.0 HOH
 4.196
 O
 O
GLU C:157 C:137 153.0 0.805 G -73.7 -18.2 153.0 0.805 0.0 HOH
 3.950
 O
 O
1jxv 1 P15531 100.0 6e-113 X-RAY
 2002-04-10 GLU A:137 A:137 155.0 0.816 G -84.8 -1.9 155.0 0.816 0.0 HOH
 3.363
 O
 O
GLU B:137 B:137 153.0 0.805 G -84.5 -2.0 153.0 0.805 0.0 HOH
 6.333
 O
 O
GLU C:137 C:137 153.0 0.805 G -85.0 -2.3 153.0 0.805 0.0 HOH
 9.028
 N
 O
GLU D:137 D:137 151.0 0.795 G -85.2 -2.6 151.0 0.795 0.0 HOH
 4.322
 O
 O
GLU E:137 E:137 154.0 0.811 G -84.9 -2.9 154.0 0.811 0.0 HOH
 3.186
 O
 O
GLU F:137 F:137 152.0 0.8 G -86.1 -1.9 152.0 0.8 0.0 HOH
 6.450
 O
 O
2hvd 1 P15531 100.0 6e-113 X-RAY
 2006-09-19 GLU A:137 A:137 184.0 0.968 T -54.6 -43.6 184.0 0.968 0.0
GLU B:137 B:137 151.0 0.795 G -73.9 -18.4 151.0 0.795 0.0 HOH
 3.446
 OE1
 O
GLU C:137 C:137 146.0 0.768 G -64.9 -10.5 146.0 0.768 0.0 HOH
 3.729
 CG
 O
4eno 1 P15531 100.0 6e-113 X-RAY
 2013-03-27 GLU A:137 A:137 139.0 0.732 G -79.2 -25.4 139.0 0.732 0.0 HOH
 3.923
 O
 O
GLU B:137 B:137 145.0 0.763 T -81.0 -10.3 145.0 0.763 0.0 HOH
 4.741
 O
 O
5ui4 1 P15531 100.0 7e-113 X-RAY
 2018-01-17 GLU A:144 A:137 185.0 0.974 G -69.6 -24.6 185.0 0.974 0.0 HOH
 6.877
 O
 O
GLU B:144 B:137 186.0 0.979 G -69.2 -24.9 186.0 0.979 0.0 HOH
 8.656
 N
 O
GLU C:144 C:137 171.0 0.9 G -67.4 -26.6 171.0 0.9 0.0 HOH
 8.611
 OE2
 O
GLU D:144 D:137 169.0 0.889 G -66.2 -28.0 169.0 0.889 0.0 HOH
 7.577
 O
 O
GLU E:144 E:137 181.0 0.953 G -67.5 -26.6 181.0 0.953 0.0 HOH
 6.645
 O
 O
GLU F:144 F:137 168.0 0.884 G -65.9 -28.2 168.0 0.884 0.0 HOH
 6.041
 O
 O
2hve 1 P15531 99.34 4e-112 X-RAY
 2006-09-19 GLU A:137 A:137 180.0 0.947 T -60.3 -39.4 180.0 0.947 0.0
GLU B:137 B:137 161.0 0.847 G -73.9 -21.0 161.0 0.847 0.0 HOH
 4.130
 O
 O
GLU C:137 C:137 155.0 0.816 G -62.8 -16.5 155.0 0.816 0.0 HOH
 4.078
 CA
 O
1ucn 1 P15531 98.68 2e-110 X-RAY
 2003-09-30 GLU A:137 A:137 147.0 0.774 G -87.6 21.6 147.0 0.774 0.0 HOH
 4.686
 O
 O
GLU B:137 B:137 149.0 0.784 G -70.0 -15.1 149.0 0.784 0.0 CA
HOH
 7.495
4.603
 OE1
N
 CA
O
GLU C:137 C:137 139.0 0.732 G -76.9 -8.0 139.0 0.732 0.0 CA
HOH
 7.228
5.928
 OE1
O
 CA
O
1bhn 1 P52174 94.08 8e-108 X-RAY
 1999-02-16 GLU A:137 A:137 160.0 0.842 G -71.8 -1.5 160.0 0.842 0.0 HOH
 3.764
 O
 O
GLU B:137 B:137 156.0 0.821 T -158.1 2.5 156.0 0.821 0.0 HOH
 3.355
 OE2
 O
GLU C:137 C:137 134.0 0.705 S -114.4 66.4 134.0 0.705 0.0 HOH
 6.696
 C
 O
GLU D:137 D:137 152.0 0.8 G -73.5 1.9 152.0 0.8 0.0 HOH
 5.200
 OE1
 O
GLU E:137 E:137 146.0 0.768 G -95.6 -7.8 146.0 0.768 0.0 HOH
 2.817
 O
 O
GLU F:137 F:137 151.0 0.795 G -79.0 17.8 151.0 0.795 0.0 HOH
 2.456
 OE1
 O
1be4 1 P52175 93.38 2e-105 X-RAY
 1999-01-13 GLU A:136 A:137 170.0 0.895 G -74.2 7.1 170.0 0.895 0.0 HOH
 4.415
 N
 O
GLU B:136 B:137 126.0 0.663 T -71.0 -30.6 126.0 0.663 0.0 HOH
 4.216
 O
 O
GLU C:136 C:137 144.0 0.758 T -64.3 -43.7 144.0 0.758 0.0 HOH
 4.541
 N
 O
1nsk 1 P22392 88.16 4e-100 X-RAY
 1995-10-15 GLU A:137 R:137 191.0 1.0 G -73.4 -2.1 191.0 1.0 0.0
GLU B:137 L:137 189.0 0.995 G -81.8 -2.4 189.0 0.995 0.0
GLU C:137 T:137 194.0 1.0 G -66.6 -4.3 194.0 1.0 0.0
GLU D:137 U:137 190.0 1.0 G -81.3 -4.6 190.0 1.0 0.0
GLU E:137 N:137 191.0 1.0 G -70.6 -5.0 191.0 1.0 0.0
GLU F:137 O:137 191.0 1.0 T -83.8 -3.3 191.0 1.0 0.0
7kpf 1 P22392 88.16 4e-100 X-RAY
 2022-02-02 GLU A:137 A:137 156.0 0.821 G -66.9 -21.9 156.0 0.821 0.0 HOH
 4.027
 O
 O
GLU B:137 B:137 175.0 0.921 G -65.5 -21.4 175.0 0.921 0.0 HOH
 4.334
 O
 O
GLU C:137 C:137 142.0 0.747 G -66.8 -20.1 142.0 0.747 0.0 HOH
 6.549
 O
 O
GLU D:137 D:137 148.0 0.779 G -76.4 -13.0 148.0 0.779 0.0 HOH
 5.811
 O
 O
GLU E:137 E:137 150.0 0.789 G -75.2 -12.7 150.0 0.789 0.0 HOH
 3.882
 O
 O
GLU F:137 F:137 142.0 0.747 G -76.5 -13.3 142.0 0.747 0.0
1nue 1 P22392 88.08 4e-99 X-RAY
 1996-04-03 GLU A:136 A:137 142.0 0.747 G -71.1 -10.7 142.0 0.747 0.0 HOH
 3.860
 O
 O
GLU B:136 B:137 137.0 0.721 G -73.1 0.2 137.0 0.721 0.0 HOH
 3.800
 O
 O
GLU C:136 C:137 146.0 0.768 G -75.0 -7.1 146.0 0.768 0.0 HOH
 4.074
 O
 O
GLU D:136 D:137 143.0 0.753 G -73.1 -6.3 143.0 0.753 0.0 HOH
 4.278
 O
 O
GLU E:136 E:137 143.0 0.753 G -73.6 -12.1 143.0 0.753 0.0 HOH
 2.688
 O
 O
GLU F:136 F:137 144.0 0.758 G -72.6 -0.2 144.0 0.758 0.0 HOH
 3.984
 O
 O
3bbb 1 P22392 88.08 4e-99 X-RAY
 2008-09-23 GLU A:136 A:137 153.0 0.805 G -69.6 -12.6 153.0 0.805 0.0 HOH
 4.179
 O
 O
GLU B:136 B:137 140.0 0.737 G -70.2 -12.8 140.0 0.737 0.0 HOH
 4.097
 O
 O
GLU C:136 C:137 163.0 0.858 G -72.0 -13.6 163.0 0.858 0.0 HOH
 2.297
 OE2
 O
GLU D:136 D:137 149.0 0.784 G -71.3 -14.3 149.0 0.784 0.0 HOH
 4.159
 O
 O
GLU E:136 E:137 151.0 0.795 G -66.7 -18.2 151.0 0.795 0.0 HOH
 3.165
 OE1
 O
GLU F:136 F:137 143.0 0.753 G -76.7 -8.9 143.0 0.753 0.0 HOH
 4.178
 O
 O
3bbf 1 P22392 88.08 4e-99 X-RAY
 2008-09-23 GLU A:136 A:137 147.0 0.774 G -66.5 -15.5 147.0 0.774 0.0 HOH
 2.724
 O
 O
GLU B:136 B:137 147.0 0.774 G -71.9 -13.5 147.0 0.774 0.0 HOH
 4.515
 O
 O
GLU C:136 C:137 147.0 0.774 G -70.7 -13.5 147.0 0.774 0.0 HOH
 4.396
 O
 O
GLU D:136 D:137 143.0 0.753 G -61.3 -24.6 143.0 0.753 0.0 HOH
 4.485
 O
 O
GLU E:136 E:137 148.0 0.779 G -71.8 -20.0 148.0 0.779 0.0 HOH
 2.607
 O
 O
GLU F:136 F:137 145.0 0.763 G -66.4 -18.2 145.0 0.763 0.0 HOH
 4.349
 O
 O
3bbc 1 P22392 87.42 3e-98 X-RAY
 2008-09-23 GLU A:136 A:137 155.0 0.816 G -78.4 -8.1 155.0 0.816 0.0 HOH
 2.660
 O
 O
GLU B:136 B:137 145.0 0.763 G -70.7 -13.1 145.0 0.763 0.0 HOH
 2.582
 O
 O
GLU C:136 C:137 150.0 0.789 G -74.5 -7.6 150.0 0.789 0.0 HOH
 2.741
 O
 O
GLU D:136 D:137 147.0 0.774 G -75.1 -8.2 147.0 0.774 0.0 HOH
 2.751
 O
 O
GLU E:136 E:137 139.0 0.732 G -70.5 -11.3 139.0 0.732 0.0 HOH
 2.654
 O
 O
GLU F:136 F:137 144.0 0.758 G -74.5 -8.5 144.0 0.758 0.0 HOH
 2.802
 OE1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15531-f1 1 P15531 100.0 3e-113 GLU A:137 A:137 153.0 0.805 G -71.5 -16.8
af-p22392-f1 1 P22392 88.16 2e-100 GLU A:137 A:137 141.0 0.742 G -69.4 -14.2
af-o60361-f1 1 O60361 84.67 2e-84 GLU A:122 A:122 139.0 0.732 G -71.1 -12.7