Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 49245622 . A C CCDS32682.1:NM_001018136.2:c.491aAg>aCg_NP_001018146.1:p.164K>T Homo sapiens NME/NM23 nucleoside diphosphate kinase 2 (NME2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1nsk 1 P22392 100.0 9e-113 X-RAY
 1995-10-15 LYS A:49 R:49 108.0 0.54 H -62.5 -36.9 108.0 0.54 0.0
LYS B:49 L:49 109.0 0.545 H -62.5 -36.9 109.0 0.545 0.0
LYS C:49 T:49 107.0 0.535 H -60.6 -39.4 107.0 0.535 0.0
LYS D:49 U:49 110.0 0.55 H -61.8 -38.1 110.0 0.55 0.0
LYS E:49 N:49 107.0 0.535 H -62.5 -37.8 107.0 0.535 0.0
LYS F:49 O:49 106.0 0.53 H -60.8 -39.5 106.0 0.53 0.0
7kpf 1 P22392 100.0 9e-113 X-RAY
 2022-02-02 LYS A:49 A:49 94.0 0.47 H -63.5 -42.5 94.0 0.47 0.0
LYS B:49 B:49 52.0 0.26 H -64.9 -39.8 52.0 0.26 0.0 HOH
 8.771
 H
 O
LYS C:49 C:49 102.0 0.51 H -65.7 -37.3 102.0 0.51 0.0 HOH
 6.150
 O
 O
LYS D:49 D:49 44.0 0.22 T -106.8 16.3 44.0 0.22 0.0 GOL
MG
HOH
 4.280
3.675
4.209
 CE
NZ
NZ
 HO3
MG
O
LYS E:49 E:49 67.0 0.335 H -76.8 -35.5 67.0 0.335 0.0 MG
HOH
 3.663
3.951
 NZ
NZ
 MG
O
LYS F:49 NA:NA DO NA DO DO DO NA NA NA
1nue 1 P22392 100.0 7e-112 X-RAY
 1996-04-03 LYS A:48 A:49 71.0 0.355 H -65.6 -35.3 71.0 0.355 0.0 HOH
 7.783
 O
 O
LYS B:48 B:49 67.0 0.335 H -67.2 -39.5 67.0 0.335 0.0 HOH
 7.265
 CB
 O
LYS C:48 C:49 81.0 0.405 H -67.9 -36.4 81.0 0.405 0.0 HOH
 7.429
 NZ
 O
LYS D:48 D:49 78.0 0.39 H -65.8 -38.1 78.0 0.39 0.0 HOH
 4.109
 NZ
 O
LYS E:48 E:49 91.0 0.455 H -67.9 -31.0 91.0 0.455 0.0 HOH
 8.860
 N
 O
LYS F:48 F:49 73.0 0.365 H -67.6 -39.7 73.0 0.365 0.0 HOH
 7.867
 O
 O
3bbb 1 P22392 100.0 7e-112 X-RAY
 2008-09-23 LYS A:48 A:49 79.0 0.395 H -56.4 -46.4 79.0 0.395 0.0 HOH
 9.588
 O
 O
LYS B:48 B:49 76.0 0.38 H -63.3 -37.8 76.0 0.38 0.0 HOH
 3.749
 CB
 O
LYS C:48 C:49 76.0 0.38 H -64.5 -35.2 76.0 0.38 0.0 HOH
 3.032
 O
 O
LYS D:48 D:49 83.0 0.415 H -62.2 -41.6 83.0 0.415 0.0 HOH
 6.533
 CD
 O
LYS E:48 E:49 71.0 0.355 H -59.8 -36.6 71.0 0.355 0.0 HOH
 4.113
 CB
 O
LYS F:48 F:49 71.0 0.355 H -67.7 -38.5 71.0 0.355 0.0 HOH
 4.034
 CB
 O
3bbf 1 P22392 100.0 7e-112 X-RAY
 2008-09-23 LYS A:48 A:49 71.0 0.355 H -62.1 -38.6 71.0 0.355 0.0 HOH
 3.191
 O
 O
LYS B:48 B:49 59.0 0.295 H -55.3 -48.0 59.0 0.295 0.0 HOH
 3.796
 CE
 O
LYS C:48 C:49 77.0 0.385 H -58.0 -37.5 77.0 0.385 0.0 HOH
 5.988
 O
 O
LYS D:48 D:49 67.0 0.335 H -55.0 -47.5 67.0 0.335 0.0 HOH
 7.368
 NZ
 O
LYS E:48 E:49 84.0 0.42 H -59.5 -39.3 84.0 0.42 0.0 HOH
 4.114
 CB
 O
LYS F:48 F:49 66.0 0.33 H -60.5 -44.1 66.0 0.33 0.0 HOH
 5.601
 CG
 O
3bbc 1 P22392 99.34 7e-111 X-RAY
 2008-09-23 LYS A:48 A:49 95.0 0.475 H -63.8 -37.3 95.0 0.475 0.0 HOH
 2.827
 O
 O
LYS B:48 B:49 71.0 0.355 H -62.6 -35.6 71.0 0.355 0.0 HOH
 3.036
 O
 O
LYS C:48 C:49 71.0 0.355 H -64.7 -38.3 71.0 0.355 0.0 HOH
 4.225
 CB
 O
LYS D:48 D:49 82.0 0.41 H -55.4 -37.0 82.0 0.41 0.0 HOH
 2.821
 NZ
 O
LYS E:48 E:49 89.0 0.445 H -56.4 -34.6 89.0 0.445 0.0 HOH
 2.866
 NZ
 O
LYS F:48 F:49 95.0 0.475 H -64.0 -38.6 95.0 0.475 0.0 HOH
 2.730
 NZ
 O
1bhn 1 P52174 90.13 1e-102 X-RAY
 1999-02-16 LYS A:49 A:49 82.0 0.41 H -70.9 -23.8 82.0 0.41 0.0 HOH
 6.220
 NZ
 O
LYS B:49 B:49 65.0 0.325 H -29.9 -50.2 65.0 0.325 0.0 HOH
 4.422
 NZ
 O
LYS C:49 C:49 77.0 0.385 H -66.6 -37.6 77.0 0.385 0.0 HOH
 3.620
 CB
 O
LYS D:49 D:49 81.0 0.405 H -68.5 -42.7 81.0 0.405 0.0 HOH
 5.629
 O
 O
LYS E:49 E:49 79.0 0.395 H -50.6 -29.7 79.0 0.395 0.0 HOH
 6.427
 N
 O
LYS F:49 F:49 99.0 0.495 H -36.8 -69.7 99.0 0.495 0.0 HOH
 3.197
 CE
 O
1be4 1 P52175 90.07 7e-102 X-RAY
 1999-01-13 LYS A:48 A:49 97.0 0.485 H -77.6 -45.1 97.0 0.485 0.0 HOH
 4.018
 C
 O
LYS B:48 B:49 78.0 0.39 H -52.9 -61.8 78.0 0.39 0.0 HOH
 3.904
 NZ
 O
LYS C:48 C:49 90.0 0.45 H -58.8 -33.4 90.0 0.45 0.0 HOH
 5.873
 NZ
 O
5ui4 1 P15531 88.16 3e-100 X-RAY
 2018-01-17 LYS A:56 A:49 101.0 0.505 H -64.3 -37.2 101.0 0.505 0.0
LYS B:56 B:49 99.0 0.495 H -64.1 -37.7 99.0 0.495 0.0
LYS C:56 C:49 101.0 0.505 H -64.1 -37.4 101.0 0.505 0.0 HOH
 8.871
 CE
 O
LYS D:56 D:49 99.0 0.495 H -64.3 -37.1 99.0 0.495 0.0
LYS E:56 E:49 75.0 0.375 H -64.0 -37.3 75.0 0.375 0.0 HOH
 7.579
 O
 O
LYS F:56 F:49 101.0 0.505 H -64.2 -36.9 101.0 0.505 0.0
1jxv 1 P15531 88.16 3e-100 X-RAY
 2002-04-10 LYS A:49 A:49 71.0 0.355 H -64.0 -39.6 71.0 0.355 0.0 HOH
 7.437
 CE
 O
LYS B:49 B:49 72.0 0.36 H -65.3 -39.8 72.0 0.36 0.0 HOH
 7.435
 CE
 O
LYS C:49 C:49 71.0 0.355 H -64.7 -38.9 71.0 0.355 0.0 HOH
 6.671
 CE
 O
LYS D:49 D:49 69.0 0.345 H -66.5 -37.0 69.0 0.345 0.0 HOH
 9.588
 NZ
 O
LYS E:49 E:49 70.0 0.35 H -65.7 -39.3 70.0 0.35 0.0 HOH
 7.718
 NZ
 O
LYS F:49 F:49 72.0 0.36 H -64.4 -39.3 72.0 0.36 0.0
2hvd 1 P15531 88.16 3e-100 X-RAY
 2006-09-19 LYS A:49 A:49 97.0 0.485 H -68.4 -44.1 97.0 0.485 0.0 HOH
 8.543
 CE
 O
LYS B:49 B:49 91.0 0.455 H -62.9 -42.0 91.0 0.455 0.0 HOH
 6.209
 O
 O
LYS C:49 C:49 67.0 0.335 H -70.1 -49.3 67.0 0.335 0.0 HOH
 4.452
 CB
 O
4eno 1 P15531 88.16 3e-100 X-RAY
 2013-03-27 LYS A:49 A:49 98.0 0.49 H -64.1 -41.5 98.0 0.49 0.0 HOH
 2.870
 NZ
 O
LYS B:49 B:49 95.0 0.475 H -63.1 -46.3 95.0 0.475 0.0 HOH
 4.304
 C
 O
3l7u 1 P15531 88.16 9e-100 X-RAY
 2010-11-10 LYS A:69 A:49 93.0 0.465 H -63.7 -36.5 93.0 0.465 0.0 HOH
 3.673
 CB
 O
LYS B:69 B:49 99.0 0.495 H -65.8 -36.0 99.0 0.495 0.0 HOH
 7.215
 NZ
 O
LYS C:69 C:49 77.0 0.385 H -58.5 -40.8 77.0 0.385 0.0 HOH
 3.935
 CB
 O
2hve 1 P15531 87.5 2e-99 X-RAY
 2006-09-19 LYS A:49 A:49 115.0 0.575 H -65.3 -42.1 115.0 0.575 0.0 HOH
 7.985
 O
 O
LYS B:49 B:49 104.0 0.52 H -65.1 -39.5 104.0 0.52 0.0 HOH
 5.896
 O
 O
LYS C:49 C:49 80.0 0.4 H -73.9 -41.4 80.0 0.4 0.0 HOH
 8.490
 O
 O
1ucn 1 P15531 86.84 8e-98 X-RAY
 2003-09-30 LYS A:49 A:49 102.0 0.51 H -53.4 -41.9 102.0 0.51 0.0 PO4
HOH
 9.105
3.871
 N
C
 O3
O
LYS B:49 B:49 106.0 0.53 H -63.3 -37.1 106.0 0.53 0.0 PO4
HOH
 9.346
2.949
 N
O
 O4
O
LYS C:49 C:49 108.0 0.54 H -65.6 -39.8 108.0 0.54 0.0 PO4
HOH
 9.267
3.152
 N
CD
 O2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22392-f1 1 P22392 100.0 4e-113 LYS A:49 A:49 81.0 0.405 H -63.5 -41.0
af-p15531-f1 1 P15531 88.16 1e-100 LYS A:49 A:49 80.0 0.4 H -65.9 -40.7
af-o60361-f1 1 O60361 96.35 7e-96 LYS A:34 A:34 87.0 0.435 H -63.2 -41.7