Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 49245648 . C A CCDS32682.1:NM_001018136.2:c.517Cga>Aga_NP_001018146.1:p.173R>R Homo sapiens NME/NM23 nucleoside diphosphate kinase 2 (NME2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1nsk 1 P22392 100.0 9e-113 X-RAY
 1995-10-15 ARG A:58 R:58 124.0 0.551 S -113.4 138.8 124.0 0.551 0.0
ARG B:58 L:58 123.0 0.547 S -120.8 134.9 123.0 0.547 0.0
ARG C:58 T:58 125.0 0.556 S -92.6 143.8 125.0 0.556 0.0
ARG D:58 U:58 117.0 0.52 S -79.2 151.2 117.0 0.52 0.0
ARG E:58 N:58 114.0 0.507 S -112.5 140.9 114.0 0.507 0.0
ARG F:58 O:58 120.0 0.533 S -73.1 145.4 120.0 0.533 0.0
7kpf 1 P22392 100.0 9e-113 X-RAY
 2022-02-02 ARG A:58 A:58 139.0 0.618 S -126.8 163.4 139.0 0.618 0.0 WYV
 2.671
 NH2
 O5A
ARG B:58 B:58 140.0 0.622 S -101.3 150.2 140.0 0.622 0.0 WYV
HOH
 2.454
8.879
 HH21
HB3
 O1A
O
ARG C:58 C:58 126.0 0.56 S -70.5 147.6 126.0 0.56 0.0 WYV
MG
HOH
 2.570
4.373
3.025
 HH22
HH21
HG2
 O3A
MG
O
ARG D:58 NA:NA DO NA DO DO DO NA NA NA
ARG E:58 NA:NA DO NA DO DO DO NA NA NA
ARG F:58 NA:NA DO NA DO DO DO NA NA NA
1nue 1 P22392 100.0 7e-112 X-RAY
 1996-04-03 ARG A:57 A:58 125.0 0.556 S -84.0 146.1 125.0 0.556 0.0 MG
GDP
HOH
 8.581
5.606
6.630
 NH1
NH1
NH1
 MG
O2A
O
ARG B:57 B:58 126.0 0.56 S -72.5 146.7 126.0 0.56 0.0 GDP
HOH
 5.634
6.142
 NH1
O
 O2A
O
ARG C:57 C:58 128.0 0.569 S -80.7 146.7 128.0 0.569 0.0 MG
GDP
HOH
 7.986
5.843
3.987
 NH1
NH1
N
 MG
O2A
O
ARG D:57 D:58 128.0 0.569 S -84.6 147.1 128.0 0.569 0.0 GDP
HOH
 6.019
2.742
 NH2
O
 O6
O
ARG E:57 E:58 132.0 0.587 S -66.2 145.3 132.0 0.587 0.0 GDP
HOH
 5.148
3.395
 NH2
N
 O2A
O
ARG F:57 F:58 118.0 0.524 S -88.4 146.7 118.0 0.524 0.0 GDP
HOH
 5.896
8.729
 NH1
CG
 N7
O
3bbb 1 P22392 100.0 7e-112 X-RAY
 2008-09-23 ARG A:57 A:58 125.0 0.556 S -100.3 151.6 125.0 0.556 0.0 HOH
 3.637
 N
 O
ARG B:57 B:58 130.0 0.578 S -79.1 144.0 130.0 0.578 0.0 DG
HOH
 3.366
2.891
 NH1
O
 O5'
O
ARG C:57 C:58 135.0 0.6 S -83.7 148.5 135.0 0.6 0.0 DA
DG
HOH
 9.455
5.510
2.697
 NE
NE
NH2
 C2
N2
O
ARG D:57 D:58 126.0 0.56 S -70.4 143.2 126.0 0.56 0.0 HOH
 2.438
 O
 O
ARG E:57 E:58 135.0 0.6 S -91.6 154.5 135.0 0.6 0.0 DA
DG
HOH
 8.895
4.572
2.627
 NH2
NH2
O
 C2
N2
O
ARG F:57 F:58 124.0 0.551 S -78.9 147.2 124.0 0.551 0.0 DG
HOH
 3.854
2.899
 NH2
NH1
 OP2
O
3bbf 1 P22392 100.0 7e-112 X-RAY
 2008-09-23 ARG A:57 A:58 124.0 0.551 S -74.6 139.9 124.0 0.551 0.0 GDP
MG
HOH
 4.942
7.524
2.848
 NH1
NH1
O
 O2A
MG
O
ARG B:57 B:58 127.0 0.564 S -74.2 145.9 127.0 0.564 0.0 GDP
MG
HOH
 4.920
7.674
3.393
 NH1
NH1
N
 O2A
MG
O
ARG C:57 C:58 133.0 0.591 S -81.5 151.2 133.0 0.591 0.0 GDP
MG
HOH
 5.723
8.373
2.923
 NH1
NH1
O
 O2A
MG
O
ARG D:57 D:58 123.0 0.547 S -71.7 145.0 123.0 0.547 0.0 GDP
MG
HOH
 6.102
9.149
2.461
 NH1
CG
O
 N7
MG
O
ARG E:57 E:58 130.0 0.578 S -73.8 150.3 130.0 0.578 0.0 GDP
MG
HOH
 4.669
7.629
3.657
 NH2
NH1
N
 O2A
MG
O
ARG F:57 F:58 127.0 0.564 S -75.0 150.0 127.0 0.564 0.0 GDP
MG
HOH
 5.742
8.124
3.520
 NH1
NH1
N
 O2A
MG
O
3bbc 1 P22392 99.34 7e-111 X-RAY
 2008-09-23 ARG A:57 A:58 122.0 0.542 S -92.7 149.0 122.0 0.542 0.0 HOH
 2.639
 O
 O
ARG B:57 B:58 131.0 0.582 S -92.9 143.6 131.0 0.582 0.0 HOH
 2.828
 NH1
 O
ARG C:57 C:58 134.0 0.596 S -125.7 153.0 134.0 0.596 0.0 HOH
 5.736
 NH2
 O
ARG D:57 D:58 126.0 0.56 S -85.3 148.7 126.0 0.56 0.0 HOH
 2.817
 O
 O
ARG E:57 E:58 127.0 0.564 S -80.9 150.7 127.0 0.564 0.0 HOH
 4.059
 NH1
 O
ARG F:57 F:58 135.0 0.6 S -85.0 143.2 135.0 0.6 0.0 HOH
 2.634
 O
 O
1bhn 1 P52174 90.13 1e-102 X-RAY
 1999-02-16 ARG A:58 A:58 143.0 0.636 S -39.7 112.9 143.0 0.636 0.0 35G
GDP
HOH
 6.041
4.952
5.057
 NH2
NH2
N
 C8
O2A
O
ARG B:58 B:58 130.0 0.578 S 3.6 114.6 130.0 0.578 0.0 35G
GDP
HOH
 5.353
5.434
2.807
 NH2
NH2
CA
 N7
O6
O
ARG C:58 C:58 117.0 0.52 S -41.3 147.0 117.0 0.52 0.0 35G
GDP
HOH
 6.514
6.107
4.121
 NH1
NH1
NH2
 C8
O2A
O
ARG D:58 D:58 134.0 0.596 -115.7 125.1 134.0 0.596 0.0 35G
GDP
HOH
 5.249
5.284
3.531
 NH2
NH2
NH2
 N7
N7
O
ARG E:58 E:58 133.0 0.591 S -35.5 111.1 133.0 0.591 0.0 35G
GDP
HOH
 6.363
4.544
2.876
 NH2
NH2
NH2
 C8
O2A
O
ARG F:58 F:58 115.0 0.511 S -10.8 148.4 115.0 0.511 0.0 35G
GDP
HOH
 6.603
6.322
3.313
 NH1
NH1
NH1
 N7
O2A
O
1be4 1 P52175 90.07 7e-102 X-RAY
 1999-01-13 ARG A:57 A:58 158.0 0.702 S -34.5 156.6 158.0 0.702 0.0 PCG
HOH
 5.501
3.339
 NH1
O
 N7
O
ARG B:57 B:58 88.0 0.391 S -133.7 89.1 88.0 0.391 0.0 PCG
HOH
 5.668
3.572
 NH2
C
 N7
O
ARG C:57 C:58 136.0 0.604 S -167.5 144.8 136.0 0.604 0.0 PCG
HOH
 6.860
2.768
 CD
NH2
 N7
O
5ui4 1 P15531 88.16 3e-100 X-RAY
 2018-01-17 ARG A:65 A:58 131.0 0.582 S -111.1 151.2 131.0 0.582 0.0 A7Z
HOH
 4.606
2.706
 NH2
NE
 C11
O
ARG B:65 B:58 126.0 0.56 S -111.7 151.6 126.0 0.56 0.0 A7Z
HOH
 3.693
3.586
 NH2
NE
 C11
O
ARG C:65 C:58 116.0 0.516 S -111.4 152.0 116.0 0.516 0.0 A7Z
HOH
 5.055
2.787
 NH1
O
 C11
O
ARG D:65 D:58 126.0 0.56 S -111.1 151.1 126.0 0.56 0.0 A7Z
 4.065
 NH2
 C11
ARG E:65 E:58 130.0 0.578 S -111.5 151.5 130.0 0.578 0.0 A7Z
HOH
 4.029
3.489
 NH2
O
 C11
O
ARG F:65 F:58 129.0 0.573 S -110.7 151.5 129.0 0.573 0.0 A7Z
 3.520
 NH2
 C11
1jxv 1 P15531 88.16 3e-100 X-RAY
 2002-04-10 ARG A:58 A:58 130.0 0.578 S -67.4 157.1 130.0 0.578 0.0
ARG B:58 B:58 131.0 0.582 S -67.7 157.0 131.0 0.582 0.0
ARG C:58 C:58 129.0 0.573 S -66.2 156.0 129.0 0.573 0.0
ARG D:58 D:58 130.0 0.578 S -67.1 157.0 130.0 0.578 0.0 HOH
 6.540
 O
 O
ARG E:58 E:58 128.0 0.569 S -68.0 157.4 128.0 0.569 0.0 HOH
 3.897
 O
 O
ARG F:58 F:58 129.0 0.573 S -67.6 157.9 129.0 0.573 0.0
2hvd 1 P15531 88.16 3e-100 X-RAY
 2006-09-19 ARG A:58 A:58 123.0 0.547 S -96.3 146.4 123.0 0.547 0.0 ADP
HOH
 6.201
4.086
 NH1
NE
 O2A
O
ARG B:58 B:58 124.0 0.551 S -103.9 146.2 124.0 0.551 0.0 ADP
HOH
 4.876
2.460
 NH1
O
 O2A
O
ARG C:58 C:58 128.0 0.569 S -100.4 154.7 128.0 0.569 0.0 ADP
HOH
 4.266
9.551
 NH1
O
 O2A
O
4eno 1 P15531 88.16 3e-100 X-RAY
 2013-03-27 ARG A:58 A:58 130.0 0.578 S -44.6 152.3 130.0 0.578 0.0 PO4
HOH
 9.920
2.921
 NH1
O
 O4
O
ARG B:58 B:58 139.0 0.618 S -72.7 156.6 139.0 0.618 0.0 PO4
 9.193
 NH1
 O2
3l7u 1 P15531 88.16 9e-100 X-RAY
 2010-11-10 ARG A:78 A:58 132.0 0.587 S -77.9 149.0 132.0 0.587 0.0 HOH
 9.756
 O
 O
ARG B:78 B:58 152.0 0.676 S -76.6 148.7 152.0 0.676 0.0 PO4
HOH
 9.347
3.949
 NH1
CB
 O2
O
ARG C:78 C:58 131.0 0.582 S -82.3 148.7 131.0 0.582 0.0 HOH
 2.680
 O
 O
2hve 1 P15531 87.5 2e-99 X-RAY
 2006-09-19 ARG A:58 A:58 123.0 0.547 S -104.1 139.2 123.0 0.547 0.0 ADP
HOH
 6.116
8.822
 NH1
NH2
 O2A
O
ARG B:58 B:58 122.0 0.542 S -103.2 148.6 122.0 0.542 0.0 ADP
HOH
 4.721
2.593
 NH1
O
 O2A
O
ARG C:58 C:58 140.0 0.622 S -64.2 156.4 140.0 0.622 0.0 ADP
HOH
 4.732
5.623
 NH2
NH2
 O2A
O
1ucn 1 P15531 86.84 8e-98 X-RAY
 2003-09-30 ARG A:58 A:58 121.0 0.538 S -66.5 141.9 121.0 0.538 0.0 CA
ADP
HOH
 9.821
5.483
2.727
 NH1
NH1
NH1
 CA
O2A
O
ARG B:58 B:58 117.0 0.52 S -84.0 148.0 117.0 0.52 0.0 ADP
HOH
 6.050
2.753
 NH1
NH2
 O2A
O
ARG C:58 C:58 121.0 0.538 S -108.5 142.0 121.0 0.538 0.0 ADP
HOH
 6.361
2.897
 CG
NH2
 N7
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p22392-f1 1 P22392 100.0 4e-113 ARG A:58 A:58 145.0 0.644 S -81.2 141.4
af-p15531-f1 1 P15531 88.16 1e-100 ARG A:58 A:58 151.0 0.671 S -81.4 141.7
af-o60361-f1 1 O60361 96.35 7e-96 ARG A:43 A:43 147.0 0.653 S -79.6 140.3