Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 78111189 . C A CCDS11767.1:NM_014740.3:c.979Gcc>Tcc_NP_055555.1:p.327A>S Homo sapiens eukaryotic translation initiation factor 4A3 (EIF4A3), mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2hyi 4 P38919 100.0 0.0 X-RAY
 2006-08-15 ALA E:327 C:327 71.0 0.617 S -57.6 -43.5 71.0 0.617 0.0 HOH
 2.908
 O
 O
ALA I:327 I:327 75.0 0.652 S -59.5 -36.8 NA NA NA
3ex7 3 P38919 100.0 0.0 X-RAY
 2008-12-09 ALA C:327 C:327 76.0 0.661 S -56.6 -35.9 76.0 0.661 0.0 HOH
 5.366
 O
 O
ALA G:327 H:327 65.0 0.565 S -56.3 -29.8 NA NA NA
2xb2 1 P38919 100.0 0.0 X-RAY
 2010-05-12 ALA A:327 A:327 66.0 0.574 S -59.7 -55.6 NA NA NA
ALA K:327 X:327 63.0 0.548 S -61.4 -57.0 63.0 0.548 0.0
4c9b 1 P38919 100.0 0.0 X-RAY
 2013-11-13 ALA A:327 A:327 71.0 0.617 S -53.9 -33.1 57.0 0.496 0.121 B:Q9HCG8:0.122
 GOL
HOH
 2.107
2.778
 O
O
 HO2
O
5mqf 30 P38919 100.0 0.0 EM
 2017-03-22 ALA NA:327 p:327 NA NA NA NA NA NA NA NA
5xjc 37 P38919 100.0 0.0 EM
 2017-07-05 ALA UA:327 u:327 71.0 0.617 S -57.6 -43.5 67.0 0.583 0.034 V:Q9HCG8:0.035
5yzg 29 P38919 100.0 0.0 EM
 2018-08-08 ALA FA:327 u:327 72.0 0.626 S -57.6 -43.5 72.0 0.626 0.0
6icz 3 P38919 100.0 0.0 EM
 2019-03-13 ALA C:327 u:327 86.0 0.748 S -57.6 -43.5 86.0 0.748 0.0
7a5p 37 P38919 100.0 0.0 EM
 2020-10-14 ALA UA:327 y:327 86.0 0.748 S -61.1 -42.5 86.0 0.748 0.0
2j0q 1 P38919 100.0 0.0 X-RAY
 2006-08-30 ALA A:326 A:327 79.0 0.687 S -66.0 -46.5 79.0 0.687 0.0
ALA B:326 B:327 79.0 0.687 S -64.3 -48.4 NA NA NA
2j0s 1 P38919 100.0 0.0 X-RAY
 2006-09-06 ALA A:326 A:327 83.0 0.722 S -69.9 -41.7 83.0 0.722 0.0 HOH
 3.850
 CB
 O
6qdv 4 P38919 100.0 0.0 EM
 2019-02-20 ALA D:306 7:327 71.0 0.617 S -57.7 -43.5 67.0 0.583 0.034 N:Q9HCG8:0.035
2hxy 1 P38919 100.0 0.0 X-RAY
 2006-08-15 ALA A:305 A:327 62.0 0.539 S -89.4 -11.2 62.0 0.539 0.0
ALA B:305 B:327 63.0 0.548 S -32.5 -41.6 NA NA NA
ALA C:305 C:327 68.0 0.591 S -37.9 -46.5 NA NA NA
ALA D:305 D:327 63.0 0.548 S -70.5 18.8 NA NA NA
2j0u 1 P38919 98.93 0.0 X-RAY
 2006-09-06 ALA A:290 A:327 73.0 0.635 S -56.3 0.6 73.0 0.635 0.0
2j0u 2 P38919 98.4 0.0 X-RAY
 2006-09-06 ALA B:290 B:327 90.0 0.783 S -58.3 -1.2 NA NA NA
6yvh 3 P38919 100.0 1e-121 X-RAY
 2020-05-13 ALA F:82 H:327 59.0 0.513 S -62.5 -40.6 38.0 0.33 0.183 A:Q9HCG8:0.183
ALA G:82 J:327 62.0 0.539 S -62.8 -41.3 44.0 0.383 0.156 B:Q9HCG8:0.157
ALA H:82 K:327 62.0 0.539 S -62.6 -40.0 39.0 0.339 0.2 E:Q9HCG8:0.2
ALA I:82 L:327 66.0 0.574 S -62.9 -40.1 45.0 0.391 0.183 D:Q9HCG8:0.183

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p38919-f1 1 P38919 100.0 0.0 ALA A:327 A:327 78.0 0.678 S -69.1 -33.1