Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 78117996 . T A CCDS11767.1:NM_014740.3:c.217Atc>Ttc_NP_055555.1:p.73I>F Homo sapiens eukaryotic translation initiation factor 4A3 (EIF4A3), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2hyi 4 P38919 100.0 0.0 X-RAY
 2006-08-15 ILE E:73 C:73 44.0 0.251 H -64.7 -34.3 44.0 0.251 0.0 HOH
 4.213
 CB
 O
ILE I:73 I:73 50.0 0.286 H -72.7 -40.2 NA NA NA
3ex7 3 P38919 100.0 0.0 X-RAY
 2008-12-09 ILE C:73 C:73 45.0 0.257 H -56.6 -33.2 45.0 0.257 0.0 HOH
 7.184
 CD1
 O
ILE G:73 H:73 47.0 0.269 H -48.8 -35.9 NA NA NA
2xb2 1 P38919 100.0 0.0 X-RAY
 2010-05-12 ILE A:73 A:73 42.0 0.24 T -77.9 12.0 NA NA NA
ILE K:73 X:73 40.0 0.229 T -78.2 11.7 40.0 0.229 0.0
4c9b 1 P38919 100.0 0.0 X-RAY
 2013-11-13 ILE A:73 A:73 34.0 0.194 H -70.5 -28.7 1.0 0.006 0.188 B:Q9HCG8:0.189
 GOL
HOH
 9.046
5.011
 C
CD1
 O1
O
5mqf 30 P38919 100.0 0.0 EM
 2017-03-22 ILE NA:73 p:73 NA NA NA NA NA NA NA NA
5xjc 37 P38919 100.0 0.0 EM
 2017-07-05 ILE UA:73 u:73 44.0 0.251 H -64.7 -34.3 44.0 0.251 0.0
5yzg 29 P38919 100.0 0.0 EM
 2018-08-08 ILE FA:73 u:73 44.0 0.251 H -64.7 -34.3 44.0 0.251 0.0
6icz 3 P38919 100.0 0.0 EM
 2019-03-13 ILE C:73 u:73 62.0 NA H -64.7 -34.3 62.0 NA NA
7a5p 37 P38919 100.0 0.0 EM
 2020-10-14 ILE UA:73 y:73 63.0 NA H -66.2 -33.5 63.0 NA NA
2j0q 1 P38919 100.0 0.0 X-RAY
 2006-08-30 ILE A:72 A:73 47.0 0.269 H -58.6 -36.4 47.0 0.269 0.0
ILE B:72 B:73 49.0 0.28 H -58.2 -35.7 NA NA NA
2j0s 1 P38919 100.0 0.0 X-RAY
 2006-09-06 ILE A:72 A:73 40.0 0.229 H -73.1 -16.1 40.0 0.229 0.0 HOH
 3.217
 CG1
 O
6qdv 4 P38919 100.0 0.0 EM
 2019-02-20 ILE D:52 7:73 46.0 0.263 H -64.7 -34.3 46.0 0.263 0.0
2hxy 1 P38919 100.0 0.0 X-RAY
 2006-08-15 ILE A:51 A:73 49.0 0.28 H -62.6 -44.1 49.0 0.28 0.0
ILE B:51 B:73 49.0 0.28 H -63.8 -44.1 NA NA NA
ILE C:51 C:73 47.0 0.269 H -64.1 -43.3 NA NA NA
ILE D:51 D:73 48.0 0.274 H -63.8 -45.3 NA NA NA
2j0u 1 P38919 98.93 0.0 X-RAY
 2006-09-06 ILE A:36 A:73 62.0 0.354 H -62.1 -41.6 62.0 0.354 0.0
2j0u 2 P38919 98.4 0.0 X-RAY
 2006-09-06 ILE B:36 B:73 64.0 0.366 H -64.6 -44.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p38919-f1 1 P38919 100.0 0.0 ILE A:73 A:73 51.0 0.291 H -62.2 -32.6