Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 79989671 . G A CCDS11798.1:NM_005052.2:c.34Ggc>Agc_NP_005043.1:p.12G>S Homo sapiens ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) (RAC3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6tm1 2 P60763 100.0 1e-143 X-RAY
 2020-01-22 GLY B:12 A:12 33.0 0.44 T -57.5 147.2 33.0 0.44 0.0
2c2h 1 P60763 99.48 3e-142 X-RAY
 2005-10-13 GLY A:12 A:12 33.0 0.44 T -54.7 140.1 33.0 0.44 0.0 GDP
MG
HOH
 3.897
6.909
2.801
 C
CA
N
 O2B
MG
O
GLY B:12 B:12 30.0 0.4 T -54.1 138.6 NA NA NA
1i4d 2 P63000 92.71 2e-134 X-RAY
 2001-05-16 GLY C:12 D:12 29.0 0.387 T -73.3 147.5 29.0 0.387 0.0 MG
GDP
HOH
 6.205
3.346
2.597
 CA
C
O
 MG
O1B
O
1i4l 2 P63000 92.71 2e-134 X-RAY
 2001-05-16 GLY C:12 D:12 30.0 0.4 T -62.3 161.0 30.0 0.4 0.0 MG
GDP
HOH
 6.740
3.526
6.145
 CA
CA
C
 MG
O3B
O
6tgc 3 P63000 92.71 2e-134 EM
 2020-07-29 GLY C:12 C:12 68.0 0.907 T -64.1 -23.6 68.0 0.907 0.0
GLY F:12 F:12 67.0 0.893 T -64.1 -23.5 67.0 0.893 0.0
5fi0 2 P63000 92.71 3e-134 X-RAY
 2016-04-20 GLY B:15 B:12 42.0 0.56 T -62.7 143.8 42.0 0.56 0.0
GLY D:15 D:12 41.0 0.547 T -62.2 142.8 NA NA NA
GLY F:15 F:12 44.0 0.587 T -61.6 143.4 NA NA NA
GLY H:15 H:12 37.0 0.493 T -62.2 143.0 NA NA NA
1i4t 2 P63000 92.19 3e-133 X-RAY
 2001-05-16 GLY C:12 D:12 11.0 0.147 T -57.0 150.5 11.0 0.147 0.0 MG
GNP
HOH
 6.971
3.331
5.231
 CA
CA
C
 MG
O1G
O
2vrw 1 P63000 95.65 7e-133 X-RAY
 2008-06-17 GLY A:12 A:12 38.0 0.507 T -58.0 149.7 38.0 0.507 0.0 HOH
 2.630
 O
 O
1e96 1 P15154 92.15 4e-132 X-RAY
 2000-11-17 GLY A:12 A:12 23.0 0.307 T -61.2 139.2 23.0 0.307 0.0 GTP
MG
HOH
 3.633
6.948
2.558
 CA
CA
O
 O2G
MG
O
1hh4 1 P15154 92.15 4e-132 X-RAY
 2001-08-28 GLY A:12 A:12 47.0 0.627 T -68.8 149.3 47.0 0.627 0.0 GDP
MG
HOH
 3.512
6.745
6.622
 C
CA
CA
 O3B
MG
O
GLY B:12 B:12 37.0 0.493 T -63.5 147.8 NA NA NA
1g4u 2 P63000 95.11 8e-132 X-RAY
 2001-01-24 GLY B:12 R:12 36.0 0.48 T -63.1 132.8 9.0 0.12 0.36 A:P74873:0.36
 MG
GDP
AF3
HOH
 7.317
4.043
3.309
2.785
 CA
C
CA
N
 MG
O3B
F2
O
2h7v 1 P63000 95.11 1e-131 X-RAY
 2006-09-19 GLY A:16 A:12 63.0 0.84 T -46.3 136.2 63.0 0.84 0.0 MG
GDP
HOH
 6.359
3.775
6.302
 CA
C
N
 MG
O1B
O
GLY B:16 B:12 53.0 0.707 T -63.2 147.5 NA NA NA
2p2l 1 P63000 95.11 1e-131 X-RAY
 2007-05-01 GLY A:16 A:12 64.0 0.853 T -49.3 137.0 64.0 0.853 0.0 ZN
GDP
HOH
 6.776
3.818
2.639
 CA
C
O
 ZN
O1B
O
GLY B:16 B:12 64.0 0.853 T -52.2 137.7 64.0 0.853 0.0 ZN
GDP
HOH
 6.842
3.864
2.654
 CA
C
O
 ZN
O1B
O
GLY C:16 C:12 66.0 0.88 T -51.2 139.8 66.0 0.88 0.0 ZN
GDP
HOH
 6.789
3.881
2.732
 CA
C
O
 ZN
O1B
O
2g0n 1 P60763 100.0 1e-131 X-RAY
 2006-05-30 GLY A:13 A:12 33.0 0.44 T -53.8 138.9 33.0 0.44 0.0 MG
CL
GDP
HOH
 7.276
3.657
3.904
2.815
 CA
CA
C
N
 MG
CL
O3B
O
GLY B:13 B:12 33.0 0.44 T -55.0 138.0 NA NA NA
2ov2 1 P60763 100.0 1e-131 X-RAY
 2007-03-13 GLY A:13 A:12 40.0 0.533 T -50.5 150.0 40.0 0.533 0.0 MG
GCP
HOH
 7.603
4.040
3.049
 CA
CA
N
 MG
O2G
O
GLY B:13 F:12 40.0 0.533 T -57.2 155.4 NA NA NA
GLY C:13 B:12 42.0 0.56 T -54.0 147.3 NA NA NA
GLY D:13 C:12 39.0 0.52 T -46.0 150.3 NA NA NA
GLY E:13 G:12 38.0 0.507 T -58.0 153.2 NA NA NA
GLY F:13 D:12 39.0 0.52 T -53.3 153.6 NA NA NA
GLY G:13 E:12 39.0 0.52 T -56.6 153.1 NA NA NA
GLY H:13 H:12 40.0 0.533 T -58.0 150.7 NA NA NA
2qme 1 P60763 100.0 1e-131 X-RAY
 2007-08-28 GLY A:13 A:12 40.0 0.533 T -54.4 145.5 40.0 0.533 0.0 MG
GCP
HOH
 7.491
3.944
2.870
 CA
CA
N
 MG
O2G
O
2ic5 1 P60763 100.0 1e-131 X-RAY
 2006-10-10 GLY A:13 A:12 33.0 0.44 T -54.5 139.1 33.0 0.44 0.0 MG
GNP
HOH
 7.142
3.515
2.613
 CA
CA
O
 MG
O2G
O
GLY B:13 B:12 32.0 0.427 T -56.0 141.4 NA NA NA
1mh1 1 P63000 95.08 9e-131 X-RAY
 1998-01-21 GLY A:14 A:12 37.0 0.493 T -58.8 141.7 37.0 0.493 0.0 MG
GNP
HOH
 7.083
3.444
2.802
 CA
CA
O
 MG
O1G
O
1ds6 1 P15153 88.54 2e-129 X-RAY
 2000-07-12 GLY A:12 A:12 48.0 0.64 T -67.4 149.2 48.0 0.64 0.0 MG
GDP
HOH
 6.374
3.486
2.905
 CA
C
N
 MG
O3B
O
2yin 2 P63000 95.48 2e-127 X-RAY
 2011-05-25 GLY C:31 C:12 54.0 0.72 G -57.4 -28.3 NA NA NA
GLY D:31 D:12 54.0 0.72 G -52.6 -34.5 54.0 0.72 0.0 HOH
 4.000
 CA
 O
2fju 1 P63000 95.48 2e-127 X-RAY
 2006-11-21 GLY A:12 A:12 35.0 0.467 T -63.9 142.2 35.0 0.467 0.0 MG
GSP
HOH
 7.477
3.417
2.690
 CA
CA
O
 MG
O3G
O
5qqd 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 GLY A:13 A:12 51.0 0.68 G -44.5 -42.5 51.0 0.68 0.0 JGA
HOH
 7.617
3.205
 O
N
 C12
O
5qqe 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 GLY A:13 A:12 49.0 0.653 G -48.2 -43.3 49.0 0.653 0.0 N5S
HOH
 7.906
3.164
 O
N
 C12
O
5qqf 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 GLY A:13 A:12 52.0 0.693 G -46.5 -41.2 52.0 0.693 0.0 N5V
HOH
 7.811
3.234
 O
C
 S
O
5qqg 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 GLY A:13 A:12 50.0 0.667 G -52.8 -37.0 50.0 0.667 0.0 N64
HOH
 7.486
3.298
 O
N
 C
O
5qqh 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 GLY A:13 A:12 50.0 0.667 G -50.1 -43.2 50.0 0.667 0.0 N67
HOH
 7.736
3.221
 O
N
 N
O
5qqi 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 GLY A:13 A:12 51.0 0.68 G -52.1 -37.8 51.0 0.68 0.0 N6D
HOH
 7.345
3.248
 O
N
 C11
O
5qqj 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 GLY A:13 A:12 50.0 0.667 G -48.0 -39.1 50.0 0.667 0.0 N6J
HOH
 7.688
3.238
 O
N
 C
O
5qqk 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 GLY A:13 A:12 51.0 0.68 G -53.4 -39.7 51.0 0.68 0.0 N6V
HOH
 7.611
3.081
 O
N
 C15
O
5qql 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 GLY A:13 A:12 50.0 0.667 G -46.8 -43.7 50.0 0.667 0.0 N71
HOH
 7.732
3.379
 O
N
 C
O
5qqm 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 GLY A:13 A:12 50.0 0.667 G -53.4 -39.8 50.0 0.667 0.0 N74
HOH
 7.682
3.091
 O
N
 C
O
5qqn 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 GLY A:13 A:12 51.0 0.68 G -47.1 -44.7 51.0 0.68 0.0 N5D
HOH
 8.244
3.266
 O
N
 O2
O
5qu9 1 P63000 95.48 2e-127 X-RAY
 2020-01-29 GLY A:13 A:12 51.0 0.68 G -53.2 -35.0 51.0 0.68 0.0 HOH
 3.169
 N
 O
1foe 2 P63000 95.48 3e-127 X-RAY
 2001-01-17 GLY B:12 B:12 35.0 0.467 S -77.6 156.4 35.0 0.467 0.0 SO4
 3.429
 CA
 O3
GLY D:12 D:12 34.0 0.453 S -78.9 158.9 NA NA NA
GLY F:12 F:12 32.0 0.427 S -80.7 156.1 NA NA NA
GLY H:12 H:12 35.0 0.467 S -77.7 156.5 NA NA NA
2nz8 1 P63000 95.48 3e-127 X-RAY
 2007-04-10 GLY A:12 A:12 53.0 0.707 G -57.0 -30.1 53.0 0.707 0.0 HOH
 2.872
 O
 O
3bji 2 P63000 95.48 3e-127 X-RAY
 2008-07-15 GLY C:12 C:12 40.0 0.533 T -79.2 159.4 NA NA NA
GLY D:12 D:12 29.0 0.387 T -61.8 156.3 29.0 0.387 0.0 HOH
 9.342
 CA
 O
5o33 1 P63000 95.48 3e-127 X-RAY
 2017-05-31 GLY A:12 A:12 43.0 0.573 T -57.6 139.6 43.0 0.573 0.0 GDP
HOH
 3.877
2.937
 C
N
 O2B
O
3su8 1 P63000 95.48 3e-127 X-RAY
 2011-09-28 GLY A:12 A:12 38.0 0.507 T -63.6 133.5 38.0 0.507 0.0 MG
GNP
 7.621
3.380
 CA
CA
 MG
O1G
3sua 1 P63000 95.48 3e-127 X-RAY
 2011-09-07 GLY A:12 A:12 29.0 0.387 T -46.5 117.7 29.0 0.387 0.0 MG
GNP
 6.645
3.477
 CA
CA
 MG
O1G
GLY B:12 B:12 28.0 0.373 T -46.4 117.9 NA NA NA
GLY C:12 C:12 28.0 0.373 T -46.8 117.6 NA NA NA
6x1g 2 P63000 95.48 3e-127 X-RAY
 2020-11-25 GLY C:12 B:12 80.0 1.0 G -64.1 -27.7 53.0 0.707 0.293 A:B3CVM3:0.36
 HOH
 3.432
 O
 O
GLY D:12 D:12 76.0 1.0 T -68.1 -17.2 NA NA NA
3b13 2 P63000 94.92 7e-127 X-RAY
 2012-03-14 GLY B:19 B:12 65.0 0.867 S -66.9 -51.5 65.0 0.867 0.0
GLY D:19 D:12 63.0 0.84 S -76.5 -47.7 63.0 0.84 0.0
1ryf 1 P63000 86.57 9e-127 X-RAY
 2004-01-27 GLY A:14 A:12 67.0 0.893 T -57.0 143.0 67.0 0.893 0.0 MG
GDP
HOH
 6.808
3.812
2.472
 CA
C
O
 MG
O3B
O
GLY B:14 B:12 66.0 0.88 T -58.1 143.2 NA NA NA
1ryh 1 P63000 86.57 9e-127 X-RAY
 2004-01-27 GLY A:14 A:12 49.0 0.653 T -59.2 139.3 49.0 0.653 0.0 MG
GNP
HOH
 7.171
3.403
2.555
 CA
CA
O
 MG
O1G
O
GLY B:14 B:12 67.0 0.893 T -53.2 135.4 NA NA NA
7dpa 2 P63000 94.92 1e-126 EM
 2021-08-04 GLY B:19 B:12 66.0 0.88 S -118.9 -5.3 66.0 0.88 0.0
GLY E:19 E:12 66.0 0.88 S -118.9 -5.3 66.0 0.88 0.0
5n6o 1 P63000 95.45 3e-126 X-RAY
 2017-12-27 GLY A:11 A:12 51.0 0.68 T -62.4 146.1 51.0 0.68 0.0 GDP
MG
HOH
 3.731
6.747
5.017
 C
CA
O
 O3B
MG
O
GLY B:11 B:12 29.0 0.387 T -67.1 148.6 NA NA NA
6bc1 1 P63000 95.45 5e-126 X-RAY
 2017-12-13 GLY A:12 A:12 35.0 0.467 T -72.3 141.2 35.0 0.467 0.0 GSP
MG
HOH
 2.751
6.669
6.021
 HA2
HA2
HA2
 HOG3
MG
O
GLY C:12 B:12 38.0 0.507 T -71.8 133.8 NA NA NA
4yon 2 P63000 94.92 5e-126 X-RAY
 2015-07-01 VAL B:14 B:12 109.0 0.703 G -54.8 -33.8 89.0 0.574 0.129 A:Q8TCU6:0.129
 HOH
 2.652
 O
 O
3th5 1 P63000 95.45 8e-126 X-RAY
 2012-07-18 GLY A:39 A:12 35.0 0.467 T -54.1 135.2 35.0 0.467 0.0 GNP
MG
HOH
 3.318
7.199
5.936
 CA
CA
N
 O1G
MG
O
GLY B:39 B:12 41.0 0.547 T -52.8 131.3 NA NA NA
3ryt 2 P63000 94.92 1e-125 X-RAY
 2012-01-18 GLY C:15 C:12 39.0 0.52 T -66.8 143.2 39.0 0.52 0.0 MG
GNP
 6.969
3.513
 CA
CA
 MG
O3G
1he1 2 P15154 95.43 1e-125 X-RAY
 2001-01-02 GLY C:12 C:12 28.0 0.373 T -62.0 137.6 8.0 0.107 0.266 A:Q51451:0.267
 GDP
AF3
MG
HOH
 3.801
3.305
7.006
2.708
 C
CA
CA
O
 O3B
F2
MG
O
GLY D:12 D:12 29.0 0.387 T -62.9 138.3 NA NA NA
6agp 1 P63000 93.37 1e-125 NMR
 2019-03-20 GLY A:12 A:12 48.0 0.64 T -57.2 146.7 48.0 0.64 0.0 GDP
MG
 2.739
5.393
 HA2
HA2
 O3B
MG
3sbd 1 P63000 94.89 2e-125 X-RAY
 2012-07-18 GLY A:22 A:12 31.0 0.413 T -49.1 130.5 31.0 0.413 0.0 GNP
MG
HOH
 3.602
7.104
2.730
 CA
CA
N
 O1G
MG
O
GLY B:22 B:12 33.0 0.44 T -51.1 129.6 NA NA NA
3sbe 1 P63000 94.89 2e-125 X-RAY
 2012-07-18 GLY A:22 A:12 32.0 0.427 T -46.6 131.7 32.0 0.427 0.0 GNP
MG
HOH
 3.673
7.287
3.956
 CA
CA
O
 O1G
MG
O
7ajk 1 P63000 94.89 3e-125 X-RAY
 2020-11-18 GLY A:15 BBB:12 33.0 0.44 T -68.7 130.0 33.0 0.44 0.0 MG
GNP
HOH
 7.050
3.271
5.818
 CA
CA
CA
 MG
N3B
O
4gzm 1 P63000 94.89 6e-125 X-RAY
 2012-12-12 GLY A:39 A:12 42.0 0.56 T -56.5 128.6 42.0 0.56 0.0 GSP
MG
 3.191
7.279
 CA
CA
 O2G
MG
GLY B:39 B:12 42.0 0.56 T -58.1 130.1 NA NA NA
4gzl 1 P63000 94.89 1e-124 X-RAY
 2012-12-12 GLY A:39 A:12 26.0 0.347 T -53.1 140.5 26.0 0.347 0.0 GNP
MG
HOH
 3.558
6.985
3.150
 CA
CA
N
 O1G
MG
O
GLY B:39 B:12 28.0 0.373 T -56.1 139.0 NA NA NA
2w2t 1 P15153 93.26 4e-124 X-RAY
 2009-05-05 VAL A:18 A:12 75.0 0.484 T -53.3 137.6 75.0 0.484 0.0 MG
GDP
HOH
 6.664
3.819
2.481
 CA
C
O
 MG
O2B
O
2w2x 1 P15153 93.26 4e-124 X-RAY
 2009-05-05 VAL A:18 A:12 72.0 0.465 T -44.7 135.6 72.0 0.465 0.0 GSP
MG
HOH
 3.985
7.470
4.374
 CG1
CA
O
 S1G
MG
O
VAL B:18 B:12 71.0 0.458 T -42.2 137.2 NA NA NA
2wkq 1 O49003,P63000 92.74 5e-124 X-RAY
 2009-08-18 GLY A:164 A:555 36.0 0.48 T -57.6 142.1 36.0 0.48 0.0 GTP
MG
CL
HOH
 3.569
7.058
6.771
2.687
 CA
CA
O
O
 O3G
MG
CL
O
2wkr 1 O49003,P63000 92.74 5e-124 X-RAY
 2009-08-18 GLY A:164 A:555 25.0 0.333 T -56.2 140.3 25.0 0.333 0.0 GTP
MG
CL
HOH
 3.428
6.883
6.712
2.893
 CA
CA
O
O
 O3G
MG
CL
O
2wkp 1 O49003,P63000 92.74 8e-124 X-RAY
 2009-08-18 GLY A:164 A:555 26.0 0.347 T -55.9 139.9 26.0 0.347 0.0 GTP
MG
HOH
 3.654
6.963
2.691
 CA
CA
O
 O2G
MG
O
2w2v 1 P15153 93.22 4e-123 X-RAY
 2009-05-05 VAL A:19 A:12 72.0 0.465 T -64.1 133.5 72.0 0.465 0.0 GTP
HOH
 3.556
2.972
 C
N
 O2B
O
VAL B:19 B:12 72.0 0.465 T -62.0 137.4 NA NA NA
VAL C:19 C:12 70.0 0.452 T -68.0 138.5 NA NA NA
VAL D:19 D:12 72.0 0.465 T -63.8 129.0 NA NA NA
5hzh 1 P63000,O49003 100.0 4e-26 X-RAY
 2016-12-21 GLY A:15 A:12 38.0 0.507 T -68.3 142.3 38.0 0.507 0.0 GTP
MG
HOH
 3.513
6.867
6.381
 CA
CA
N
 O2G
MG
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60763-f1 1 P60763 100.0 5e-144 GLY A:12 A:12 31.0 0.413 T -54.4 146.0
af-p63000-f1 1 P63000 92.71 8e-135 GLY A:12 A:12 32.0 0.427 T -54.2 146.0
af-p15153-f1 1 P15153 88.54 7e-130 GLY A:12 A:12 33.0 0.44 T -54.3 145.6