Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 79991409 . C A CCDS11798.1:NM_005052.2:c.382Cgg>Agg_NP_005043.1:p.128R>R Homo sapiens ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) (RAC3), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6tm1 2 P60763 100.0 1e-143 X-RAY
 2020-01-22 ARG B:128 A:128 196.0 0.871 H -73.0 -25.3 196.0 0.871 0.0
2c2h 1 P60763 99.48 3e-142 X-RAY
 2005-10-13 ARG A:128 A:128 121.0 NA H -67.4 -40.2 121.0 NA NA HOH
 5.102
 NE
 O
ARG B:128 B:128 119.0 NA H -67.6 -27.8 NA NA NA
1i4d 2 P63000 92.71 2e-134 X-RAY
 2001-05-16 LYS C:128 D:128 77.0 0.385 H -54.8 -45.8 77.0 0.385 0.0 HOH
 3.224
 CB
 O
1i4l 2 P63000 92.71 2e-134 X-RAY
 2001-05-16 LYS C:128 D:128 108.0 0.54 H -68.4 -15.6 108.0 0.54 0.0 HOH
 2.928
 CE
 O
6tgc 3 P63000 92.71 2e-134 EM
 2020-07-29 LYS C:128 C:128 97.0 0.485 H -93.2 10.4 97.0 0.485 0.0
LYS F:128 F:128 98.0 0.49 H -93.2 10.4 98.0 0.49 0.0
5fi0 2 P63000 92.71 3e-134 X-RAY
 2016-04-20 LYS B:131 B:128 134.0 0.67 H -64.0 -38.9 134.0 0.67 0.0 PO4
 9.801
 NZ
 O3
LYS D:131 D:128 156.0 0.78 H -67.4 -36.3 NA NA NA
LYS F:131 F:128 147.0 0.735 H -65.4 -38.5 NA NA NA
LYS H:131 H:128 149.0 0.745 H -66.8 -36.1 NA NA NA
1i4t 2 P63000 92.19 3e-133 X-RAY
 2001-05-16 LYS C:128 D:128 105.0 0.525 H -72.1 -26.7 105.0 0.525 0.0 HOH
 4.480
 C
 O
2vrw 1 P63000 95.65 7e-133 X-RAY
 2008-06-17 LYS A:128 A:128 105.0 0.525 H -69.3 -25.3 105.0 0.525 0.0 HOH
 6.076
 N
 O
1e96 1 P15154 92.15 4e-132 X-RAY
 2000-11-17 LYS A:128 A:128 102.0 0.51 H -67.5 -35.9 102.0 0.51 0.0 HOH
 3.419
 CB
 O
1hh4 1 P15154 92.15 4e-132 X-RAY
 2001-08-28 LYS A:128 A:128 67.0 NA H -62.1 -18.4 67.0 NA NA HOH
 8.616
 O
 O
LYS B:128 B:128 62.0 NA H -61.4 -21.2 NA NA NA
1g4u 2 P63000 95.11 8e-132 X-RAY
 2001-01-24 LYS B:128 R:128 130.0 0.65 H -68.2 -42.0 65.0 0.325 0.325 A:P74873:0.325
 HOH
 2.876
 NZ
 O
2h7v 1 P63000 95.11 1e-131 X-RAY
 2006-09-19 LYS A:132 A:128 91.0 0.455 H -49.7 -50.1 91.0 0.455 0.0
LYS B:132 B:128 136.0 0.68 H -58.6 -32.9 NA NA NA
2p2l 1 P63000 95.11 1e-131 X-RAY
 2007-05-01 LYS A:132 A:128 98.0 0.49 H -57.7 -44.1 98.0 0.49 0.0 ZN
HOH
 5.702
3.361
 N
CB
 ZN
O
LYS B:132 B:128 132.0 0.66 H -58.4 -33.3 132.0 0.66 0.0 HOH
 3.792
 CD
 O
LYS C:132 C:128 144.0 0.72 H -66.2 -37.4 144.0 0.72 0.0 HOH
 3.175
 CE
 O
2g0n 1 P60763 100.0 1e-131 X-RAY
 2006-05-30 ARG A:129 A:128 125.0 0.556 H -52.3 -46.1 125.0 0.556 0.0 GDP
HOH
 9.759
2.585
 NH1
O
 N2
O
ARG B:129 B:128 135.0 0.6 H -57.1 -48.0 NA NA NA
2ov2 1 P60763 100.0 1e-131 X-RAY
 2007-03-13 ARG A:129 A:128 59.0 NA H -70.7 -34.1 59.0 NA NA HOH
 4.289
 CB
 O
ARG B:129 F:128 153.0 0.68 H -57.8 -40.6 NA NA NA
ARG C:129 B:128 158.0 0.702 H -61.6 -35.5 NA NA NA
ARG D:129 C:128 151.0 0.671 H -61.8 -36.4 NA NA NA
ARG E:129 G:128 154.0 0.684 H -64.5 -38.2 NA NA NA
ARG F:129 D:128 161.0 0.716 H -71.4 -39.1 NA NA NA
ARG G:129 E:128 146.0 0.649 H -61.1 -36.1 NA NA NA
ARG H:129 H:128 145.0 0.644 H -65.5 -27.3 NA NA NA
2qme 1 P60763 100.0 1e-131 X-RAY
 2007-08-28 ARG A:129 A:128 126.0 0.56 H -56.3 -42.2 126.0 0.56 0.0 GCP
HOH
 9.116
2.647
 NH1
O
 N2
O
2ic5 1 P60763 100.0 1e-131 X-RAY
 2006-10-10 ARG A:129 A:128 127.0 0.564 H -51.8 -50.0 127.0 0.564 0.0 GNP
HOH
 9.898
2.705
 NH1
O
 N2
O
ARG B:129 B:128 134.0 0.596 H -53.1 -50.8 NA NA NA
1mh1 1 P63000 95.08 9e-131 X-RAY
 1998-01-21 LYS A:130 A:128 57.0 NA H -58.6 -39.3 57.0 NA NA HOH
 2.655
 O
 O
1ds6 1 P15153 88.54 2e-129 X-RAY
 2000-07-12 LYS A:128 A:128 90.0 0.45 H -63.2 -40.2 90.0 0.45 0.0 HOH
 3.261
 CB
 O
2yin 2 P63000 95.48 2e-127 X-RAY
 2011-05-25 LYS C:147 C:128 115.0 0.575 H -63.6 -32.4 NA NA NA
LYS D:147 D:128 116.0 0.58 H -64.2 -37.5 116.0 0.58 0.0
2fju 1 P63000 95.48 2e-127 X-RAY
 2006-11-21 LYS A:128 A:128 143.0 0.715 H -56.6 -42.0 143.0 0.715 0.0 GSP
HOH
 9.454
7.844
 NZ
NZ
 O3'
O
5qqd 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 LYS A:129 A:128 53.0 NA H -61.6 -45.1 53.0 NA NA HOH
 2.359
 O
 O
5qqe 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 LYS A:129 A:128 52.0 NA H -64.7 -34.7 52.0 NA NA HOH
 2.639
 O
 O
5qqf 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 LYS A:129 A:128 51.0 NA H -59.7 -32.8 51.0 NA NA HOH
 3.132
 O
 O
5qqg 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 LYS A:129 A:128 49.0 NA H -58.0 -39.9 49.0 NA NA HOH
 2.435
 O
 O
5qqh 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 LYS A:129 A:128 49.0 NA H -60.2 -40.6 49.0 NA NA N67
HOH
 8.580
2.350
 CB
O
 O1
O
5qqi 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 LYS A:129 A:128 47.0 NA H -58.3 -45.4 47.0 NA NA HOH
 2.403
 O
 O
5qqj 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 LYS A:129 A:128 49.0 NA H -53.7 -41.1 49.0 NA NA N6J
HOH
 7.653
2.331
 CB
O
 C11
O
5qqk 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 LYS A:129 A:128 48.0 NA H -58.6 -41.2 48.0 NA NA N6V
HOH
 7.773
2.411
 CB
O
 C
O
5qql 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 LYS A:129 A:128 52.0 NA H -57.7 -40.5 52.0 NA NA HOH
 2.478
 O
 O
5qqm 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 LYS A:129 A:128 49.0 NA H -59.2 -39.8 49.0 NA NA HOH
 2.469
 O
 O
5qqn 1 P63000 95.48 2e-127 X-RAY
 2019-12-18 LYS A:129 A:128 50.0 NA H -59.0 -37.7 50.0 NA NA N5D
HOH
 7.239
2.393
 CB
O
 C11
O
5qu9 1 P63000 95.48 2e-127 X-RAY
 2020-01-29 LYS A:129 A:128 52.0 NA H -66.3 -35.3 52.0 NA NA HOH
 2.504
 O
 O
1foe 2 P63000 95.48 3e-127 X-RAY
 2001-01-17 LYS B:128 B:128 86.0 0.43 H -53.6 -45.7 86.0 0.43 0.0
LYS D:128 D:128 87.0 0.435 H -53.8 -46.1 NA NA NA
LYS F:128 F:128 88.0 0.44 H -54.6 -45.9 NA NA NA
LYS H:128 H:128 87.0 0.435 H -53.4 -45.3 NA NA NA
2nz8 1 P63000 95.48 3e-127 X-RAY
 2007-04-10 LYS A:128 A:128 132.0 0.66 H -64.4 -42.2 132.0 0.66 0.0 HOH
 5.921
 NZ
 O
3bji 2 P63000 95.48 3e-127 X-RAY
 2008-07-15 LYS C:128 C:128 57.0 NA H -75.0 -32.3 NA NA NA
LYS D:128 NA:NA DO NA DO DO DO NA NA NA
5o33 1 P63000 95.48 3e-127 X-RAY
 2017-05-31 LYS A:128 A:128 57.0 NA H -66.9 -37.0 57.0 NA NA HOH
 3.264
 CB
 O
3su8 1 P63000 95.48 3e-127 X-RAY
 2011-09-28 LYS A:128 A:128 155.0 0.775 H -66.8 -37.6 155.0 0.775 0.0
3sua 1 P63000 95.48 3e-127 X-RAY
 2011-09-07 LYS A:128 A:128 164.0 0.82 H -66.7 -35.2 164.0 0.82 0.0
LYS B:128 B:128 155.0 0.775 H -66.5 -35.4 NA NA NA
LYS C:128 C:128 164.0 0.82 H -66.7 -35.4 NA NA NA
6x1g 2 P63000 95.48 3e-127 X-RAY
 2020-11-25 LYS C:128 B:128 129.0 0.645 H -56.5 -52.4 129.0 0.645 0.0 HOH
 8.275
 NZ
 O
LYS D:128 D:128 112.0 0.56 H -56.8 -52.4 NA NA NA
3b13 2 P63000 94.92 7e-127 X-RAY
 2012-03-14 LYS B:135 B:128 113.0 0.565 H -54.4 -47.3 113.0 0.565 0.0
LYS D:135 D:128 119.0 0.595 H -59.8 -45.5 119.0 0.595 0.0
1ryf 1 P63000 86.57 9e-127 X-RAY
 2004-01-27 LYS A:149 A:147 137.0 0.685 H -59.0 -38.4 137.0 0.685 0.0 HOH
 5.867
 N
 O
LYS B:149 B:147 137.0 0.685 H -57.9 -46.6 NA NA NA
1ryh 1 P63000 86.57 9e-127 X-RAY
 2004-01-27 LYS A:149 A:147 127.0 0.635 H -77.3 -30.0 127.0 0.635 0.0 HOH
 4.719
 NZ
 O
LYS B:149 B:147 157.0 0.785 H -58.3 -46.7 NA NA NA
7dpa 2 P63000 94.92 1e-126 EM
 2021-08-04 LYS B:135 B:128 120.0 0.6 H -63.3 -27.4 120.0 0.6 0.0
LYS E:135 E:128 119.0 0.595 H -63.4 -27.3 119.0 0.595 0.0
5n6o 1 P63000 95.45 3e-126 X-RAY
 2017-12-27 LYS A:127 A:128 115.0 0.575 H -58.7 -43.1 115.0 0.575 0.0 GDP
HOH
 8.968
8.856
 NZ
O
 HN21
O
LYS B:127 B:128 126.0 0.63 H -68.8 -31.0 NA NA NA
6bc1 1 P63000 95.45 5e-126 X-RAY
 2017-12-13 LYS A:128 A:128 105.0 0.525 H -65.8 -21.1 105.0 0.525 0.0 GSP
HOH
 9.033
1.585
 HZ2
H
 HN21
O
LYS C:128 B:128 110.0 0.55 H -63.7 -18.1 NA NA NA
4yon 2 P63000 94.92 5e-126 X-RAY
 2015-07-01 LYS B:130 B:128 129.0 0.645 H -65.8 -36.6 129.0 0.645 0.0 HOH
 2.824
 O
 O
3th5 1 P63000 95.45 8e-126 X-RAY
 2012-07-18 LYS A:155 A:128 136.0 0.68 H -73.2 -27.2 136.0 0.68 0.0
LYS B:155 B:128 129.0 0.645 H -60.4 -44.4 NA NA NA
3ryt 2 P63000 94.92 1e-125 X-RAY
 2012-01-18 LYS C:131 C:128 62.0 NA H -87.8 6.7 62.0 NA NA
1he1 2 P15154 95.43 1e-125 X-RAY
 2001-01-02 LYS C:128 C:128 120.0 0.6 H -62.7 -36.8 85.0 0.425 0.175 A:Q51451:0.175
 HOH
 3.114
 CE
 O
LYS D:128 D:128 116.0 0.58 H -64.0 -36.3 NA NA NA
6agp 1 P63000 93.37 1e-125 NMR
 2019-03-20 LYS A:128 A:128 89.0 0.445 H -60.0 -37.3 89.0 0.445 0.0
3sbd 1 P63000 94.89 2e-125 X-RAY
 2012-07-18 LYS A:138 A:128 119.0 0.595 H -78.6 -15.0 119.0 0.595 0.0 HOH
 9.684
 O
 O
LYS B:138 B:128 122.0 0.61 H -57.4 -51.3 NA NA NA
3sbe 1 P63000 94.89 2e-125 X-RAY
 2012-07-18 LYS A:138 A:128 114.0 0.57 H -58.8 -33.3 114.0 0.57 0.0 GNP
HOH
 9.193
9.173
 NZ
O
 N2
O
7ajk 1 P63000 94.89 3e-125 X-RAY
 2020-11-18 LYS A:131 BBB:128 130.0 0.65 H -67.8 -39.2 130.0 0.65 0.0
4gzm 1 P63000 94.89 6e-125 X-RAY
 2012-12-12 LYS A:155 A:128 112.0 0.56 H -85.2 -44.8 112.0 0.56 0.0
LYS B:155 B:128 112.0 0.56 H -84.5 -44.9 NA NA NA
4gzl 1 P63000 94.89 1e-124 X-RAY
 2012-12-12 LYS A:155 A:128 121.0 0.605 H -56.9 -46.5 121.0 0.605 0.0 HOH
 2.699
 O
 O
LYS B:155 B:128 125.0 0.625 H -68.3 -45.1 NA NA NA
2w2t 1 P15153 93.26 4e-124 X-RAY
 2009-05-05 LYS A:134 A:128 108.0 0.54 H -57.7 -42.3 108.0 0.54 0.0 HOH
 4.922
 NZ
 O
2w2x 1 P15153 93.26 4e-124 X-RAY
 2009-05-05 LYS A:134 A:128 50.0 NA H -60.2 -40.0 50.0 NA NA
LYS B:134 B:128 70.0 NA H -59.3 -41.4 NA NA NA
2wkq 1 O49003,P63000 92.74 5e-124 X-RAY
 2009-08-18 LYS A:280 A:671 120.0 0.6 H -63.0 -40.7 120.0 0.6 0.0 HOH
 3.692
 CB
 O
2wkr 1 O49003,P63000 92.74 5e-124 X-RAY
 2009-08-18 LYS A:280 A:671 137.0 0.685 H -60.3 -43.9 137.0 0.685 0.0 HOH
 3.685
 CB
 O
2wkp 1 O49003,P63000 92.74 8e-124 X-RAY
 2009-08-18 LYS A:280 A:671 113.0 0.565 H -63.2 -43.7 113.0 0.565 0.0 GTP
HOH
 9.383
3.628
 NZ
NZ
 N2
O
2w2v 1 P15153 93.22 4e-123 X-RAY
 2009-05-05 LYS A:135 A:128 41.0 NA H -60.8 -54.4 41.0 NA NA HOH
 6.534
 CB
 O
LYS B:135 B:128 91.0 NA H -54.7 -40.1 NA NA NA
LYS C:135 NA:NA DO NA DO DO DO NA NA NA
LYS D:135 D:128 40.0 NA H -68.8 -37.3 NA NA NA
5hzh 1 P63000,O49003 86.81 4e-90 X-RAY
 2016-12-21 LYS A:280 A:277 129.0 0.645 H -62.7 -37.5 129.0 0.645 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60763-f1 1 P60763 100.0 5e-144 ARG A:128 A:128 173.0 0.769 H -60.3 -35.8
af-p63000-f1 1 P63000 92.71 8e-135 LYS A:128 A:128 131.0 0.655 H -59.2 -35.2
af-p15153-f1 1 P15153 88.54 7e-130 LYS A:128 A:128 130.0 0.65 H -59.6 -35.2