Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr17 8065041 . C A CCDS32561.1:NM_014232.2:c.167cGa>cTa_NP_055047.2:p.56R>L Homo sapiens vesicle associated membrane protein 2 (VAMP2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1sfc 1 P63045 98.96 4e-66 X-RAY
 1998-10-28 ARG A:56 A:56 152.0 0.676 H -74.4 -41.0 0.0 0.0 0.676 B:P32851:0.231
D:P60881:0.373
C:P60881:0.387
 SR
HOH
 9.114
7.958
 NH1
NH1
 SR
O
ARG E:56 E:56 163.0 0.724 H -61.8 -30.3 NA NA NA
ARG I:56 I:56 153.0 0.68 H -55.2 -36.7 NA NA NA
6ip1 1 P63045 98.94 3e-64 EM
 2019-04-24 ARG A:59 A:56 145.0 0.644 H -72.6 -15.0 0.0 0.0 0.644 B:P32851:0.24
D:P60881:0.347
C:P60881:0.32
6mdm 4 P63045 98.88 2e-60 EM
 2018-09-19 ARG I:84 J:56 102.0 0.453 H -69.5 -59.4 10.0 0.044 0.409 H:P32851:0.231
G:P60881:0.204
6mdn 4 P63045 98.88 2e-60 EM
 2018-09-19 ARG I:84 J:56 104.0 0.462 H -61.3 -55.9 3.0 0.013 0.449 H:P32851:0.173
G:P60881:0.307
3hd7 1 P63045 100.0 1e-59 X-RAY
 2009-07-14 ARG A:31 A:56 164.0 0.729 H -63.9 -20.7 0.0 0.0 0.729 B:P32851:0.311
D:P60881:0.36
C:P60881:0.338
ARG E:31 E:56 162.0 0.72 H -56.6 -30.3 NA NA NA
3ipd 1 P63045 100.0 1e-59 X-RAY
 2009-09-01 ARG A:31 A:56 155.0 0.689 H -61.0 -46.7 7.0 0.031 0.658 D:P60881:0.347
C:P60881:0.307
B:P32851:0.196
ARG E:31 E:56 155.0 0.689 H -61.3 -46.4 NA NA NA
2n1t 1 P63045 100.0 2e-45 NMR
 2015-06-03 ARG A:32 A:56 170.0 0.756 H -61.6 -41.8 2.0 0.009 0.747 D:P60880:0.356
C:P60880:0.311
B:P32851:0.293
1kil 1 P63045 100.0 3e-42 X-RAY
 2002-03-13 ARG A:30 A:56 170.0 0.756 H -55.7 -41.3 0.0 0.0 0.756 D:P60880:0.373
B:P32851:0.311
C:P60880:0.391
 MG
HOH
 9.348
6.620
 NH2
N
 MG
O
1n7s 1 P63045 100.0 4e-39 X-RAY
 2002-12-27 ARG A:30 A:56 157.0 0.698 H -61.5 -37.9 0.0 0.0 0.698 D:P60881:0.364
B:P32851:0.244
C:P60881:0.4
 HOH
 2.960
 CD
 O
3j96 3 P63045 100.0 4e-39 EM
 2015-01-28 ARG K:30 K:56 158.0 0.702 H -73.1 -5.5 14.0 0.062 0.64 L:P32851:0.413
M:None:0.356
3j97 3 P63045 100.0 4e-39 EM
 2015-01-28 ARG K:30 K:56 149.0 0.662 H -70.8 -45.3 2.0 0.009 0.653 L:P32851:0.058
M:None:0.622
3j98 3 P63045 100.0 4e-39 EM
 2015-01-28 ARG K:30 K:56 138.0 0.613 H -74.6 -34.4 5.0 0.022 0.591 M:None:0.569
L:P32851:0.044
3j99 3 P63045 100.0 4e-39 EM
 2015-01-28 ARG K:30 K:56 139.0 0.618 H -74.6 -34.4 5.0 0.022 0.596 M:None:0.573
L:P32851:0.049
5ccg 1 P63045 100.0 4e-39 X-RAY
 2015-08-12 ARG A:30 A:56 158.0 0.702 H -58.9 -37.3 0.0 0.0 0.702 D:P60881:0.387
B:P32851:0.222
C:P60881:0.387
 CA
CA
CA
 6.433
7.945
9.050
 N
N
NH2
 CA
CA
CA
ARG G:30 G:56 159.0 0.707 H -59.8 -39.2 NA NA NA
5cch 1 P63045 100.0 4e-39 X-RAY
 2015-08-12 ARG A:30 A:56 154.0 0.684 H -56.0 -38.4 0.0 0.0 0.684 B:P32851:0.253
D:P60881:0.364
C:P60881:0.36
5cci 1 P63045 100.0 4e-39 X-RAY
 2015-08-12 ARG A:30 A:56 161.0 0.716 H -58.7 -36.3 0.0 0.0 0.716 B:P32851:0.28
D:P60881:0.347
C:P60881:0.373
5kj7 1 P63025 100.0 4e-39 X-RAY
 2016-10-19 ARG A:30 A:56 158.0 0.702 H -61.0 -36.4 0.0 0.0 0.702 B:P32851:0.236
D:P60881:0.373
C:P60881:0.378
 CA
CA
CA
 6.293
8.020
8.974
 N
N
NH2
 CA
CA
CA
ARG G:30 G:56 158.0 0.702 H -62.0 -37.5 NA NA NA
5kj8 1 P63025 100.0 4e-39 X-RAY
 2016-10-19 ARG A:30 A:56 159.0 0.707 H -55.0 -37.7 0.0 0.0 0.707 B:P32851:0.227
C:P60881:0.387
D:P60881:0.382
 CA
 8.724
 NH2
 CA
ARG G:30 G:56 160.0 0.711 H -56.7 -38.3 NA NA NA
6mti 3 P63045 100.0 4e-39 EM
 2019-04-24 ARG G:30 A:56 163.0 0.724 H -58.7 -36.3 1.0 0.004 0.72 H:P32851:0.284
I:P60881:0.373
J:P60881:0.351
ARG K:30 E:56 161.0 0.716 H -58.7 -36.4 0.0 0.0 0.716 N:P60881:0.356
M:P60881:0.378
L:P32851:0.271
ARG O:30 I:56 163.0 0.724 H -58.7 -36.3 1.0 0.004 0.72 Q:P60881:0.378
R:P60881:0.351
P:P32851:0.28
ARG S:30 M:56 162.0 0.72 H -58.7 -36.4 0.0 0.0 0.72 V:P60881:0.347
T:P32851:0.284
U:P60881:0.378
ARG W:30 Q:56 161.0 0.716 H -58.6 -36.4 1.0 0.004 0.712 Y:P60881:0.373
X:P32851:0.28
Z:P60881:0.347
ARG AA:30 U:56 160.0 0.711 H -58.7 -36.4 1.0 0.004 0.707 BA:P32851:0.276
CA:P60881:0.373
DA:P60881:0.342
6wvw 1 P63045 100.0 4e-39 X-RAY
 2021-03-17 ARG A:30 A:56 158.0 0.702 H -59.0 -41.2 0.0 0.0 0.702 D:P60881:0.351
B:P32851:0.258
C:P60881:0.382
 CA
HOH
 7.970
6.288
 HH21
HB2
 CA
O
ARG E:30 E:56 162.0 0.72 H -59.5 -41.2 NA NA NA
1l4a 1 P47194 86.57 2e-37 X-RAY
 2002-07-31 ARG A:41 A:65 168.0 0.747 H -75.9 -27.6 6.0 0.027 0.72 B:O46345:0.258
C:Q8T3S4:0.396
D:Q8T3S4:0.391
 HOH
 7.423
 N
 O
5w5c 1 P63045 100.0 1e-20 X-RAY
 2017-08-23 ARG A:30 A:56 161.0 0.716 H -54.9 -41.5 0.0 0.0 0.716 D:P60881:0.382
B:P32851:0.258
C:P60881:0.396
 MG
HOH
 9.199
3.015
 NH2
CD
 MG
O
5w5d 1 P63045 100.0 1e-20 X-RAY
 2017-08-23 ARG A:30 A:56 159.0 0.707 H -59.3 -42.0 0.0 0.0 0.707 B:P32851:0.249
C:P60881:0.4
D:P60881:0.378
 MG
HOH
 9.778
3.091
 NH2
CD
 MG
O
3fie 2 P63027 100.0 4e-19 X-RAY
 2009-06-23 ARG C:35 C:56 186.0 0.827 -153.7 173.2 69.0 0.307 0.52 A:Q57236:0.52
 ZN
HOH
 7.511
2.926
 O
N
 ZN
O
ARG D:35 D:56 185.0 0.822 -158.2 174.8 NA NA NA
3rk2 1 P63027 97.14 2e-16 X-RAY
 2011-07-27 ARG A:33 A:56 161.0 0.716 H -67.9 -27.8 0.0 0.0 0.716 D:P60880:0.36
B:P32851:0.267
C:P60880:0.404
 HOH
 6.511
 O
 O
ARG E:33 E:56 160.0 0.711 H -68.1 -34.8 NA NA NA
3rk3 1 P63027 97.14 2e-16 X-RAY
 2011-07-27 ARG A:33 A:56 171.0 0.76 H -55.8 -62.6 2.0 0.009 0.751 B:P32851:0.293
D:P60880:0.342
C:P60880:0.427
3rl0 1 P63027 97.14 2e-16 X-RAY
 2011-07-27 ARG A:33 A:56 164.0 0.729 H -64.3 -34.7 1.0 0.004 0.725 B:P32851:0.262
D:P60880:0.387
C:P60880:0.307
ARG E:33 E:56 163.0 0.724 H -63.3 -35.1 NA NA NA
ARG I:33 I:56 163.0 0.724 H -65.0 -35.2 NA NA NA
ARG M:33 M:56 162.0 0.72 H -64.4 -34.9 NA NA NA
ARG Q:33 Q:56 163.0 0.724 H -63.3 -35.8 NA NA NA
ARG U:33 U:56 162.0 0.72 H -64.1 -34.5 NA NA NA
ARG Y:33 Y:56 164.0 0.729 H -65.0 -35.1 NA NA NA
ARG CA:33 c:56 165.0 0.733 H -65.2 -35.0 NA NA NA
3fii 2 P63027 100.0 5e-14 X-RAY
 2009-06-23 ARG B:30 B:56 190.0 0.844 -156.0 -177.3 74.0 0.329 0.515 A:Q57236:0.516
 ZN
HOH
 7.284
4.662
 C
NH2
 ZN
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p63027-f1 1 P63027 100.0 9e-83 ARG A:56 A:56 174.0 0.773 H -69.4 -37.8
af-q15836-f1 1 Q15836 86.42 5e-44 ARG A:39 A:39 162.0 0.72 H -64.3 -42.2