Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr18 747990 . T A CCDS11824.1:NM_005433.3:c.400Atc>Ttc_NP_005424.1:p.134I>F Homo sapiens YES proto-oncogene 1, Src family tyrosine kinase (YES1), mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2h8h 1 P12931 82.24 0.0 X-RAY
 2006-11-21 LEU A:126 A:124 78.0 0.459 T -78.0 -8.6 78.0 0.459 0.0 HOH
 2.631
 O
 O
2ptk 1 P00523 84.11 0.0 X-RAY
 1997-12-24 LEU A:44 A:124 64.0 0.376 T -75.5 -16.3 64.0 0.376 0.0 HOH
 2.998
 O
 O
1fmk 1 P12931 84.26 0.0 X-RAY
 1997-08-20 LEU A:43 A:124 111.0 0.653 T -82.9 -0.2 111.0 0.653 0.0 HOH
 2.490
 O
 O
1y57 1 P12931 84.26 0.0 X-RAY
 2005-06-21 LEU A:43 A:124 93.0 0.547 T -83.7 -6.0 93.0 0.547 0.0 HOH
 2.582
 O
 O
2src 1 P12931 84.26 0.0 X-RAY
 1999-07-22 LEU A:43 A:124 74.0 0.435 T -74.8 -14.5 74.0 0.435 0.0 HOH
 5.757
 CD1
 O
1ksw 1 P12931 84.04 0.0 X-RAY
 2002-02-27 LEU A:43 A:124 66.0 0.388 S -80.3 -37.7 66.0 0.388 0.0 HOH
 4.366
 CD2
 O
6f3f 1 Q3UKD6 83.81 0.0 X-RAY
 2017-12-27 LEU A:46 A:124 71.0 0.418 T -68.4 -13.3 71.0 0.418 0.0 HOH
 5.057
 O
 O
4k11 1 P12931 83.93 0.0 X-RAY
 2014-04-09 LEU A:41 A:124 82.0 0.482 T -70.0 -7.1 82.0 0.482 0.0 HOH
 6.858
 N
 O
3uf4 1 P39688 80.75 3e-94 X-RAY
 2011-12-07 LEU A:45 A:125 68.0 0.4 T -90.1 11.9 68.0 0.4 0.0 GOL
HOH
 6.237
3.796
 O
CD2
 O2
O
2hda 1 P07947 96.88 5e-37 X-RAY
 2007-04-17 ILE A:46 A:134 84.0 0.48 T -70.5 -32.7 84.0 0.48 0.0 HOH
 4.815
 C
 O
7a2v 1 P06241 81.67 9e-30 X-RAY
 2021-08-25 LEU A:43 A:125 94.0 0.553 T -75.0 -9.4 94.0 0.553 0.0 HOH
 4.191
 O
 O
7a2u 1 P06241 81.67 1e-29 X-RAY
 2021-08-25 LEU A:43 A:125 76.0 0.447 T -75.3 -14.0 76.0 0.447 0.0 HOH
 3.030
 HB3
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p07947-f1 1 P07947 100.0 0.0 ILE A:134 A:134 94.0 0.537 T -71.3 -33.7
af-p12931-f1 1 P12931 82.24 0.0 LEU A:127 A:127 87.0 0.512 T -74.6 -12.6