Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr18 45368256 . A C CCDS11934.1:NM_001003652.3:c.1346tTg>tGg_NP_001003652.1:p.449L>W Homo sapiens SMAD family member 2 (SMAD2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 100.0 1e-169 X-RAY
 2002-02-06 LEU A:209 A:449 3.0 0.018 H -62.4 -39.2 0.0 0.0 0.018 A:Q15796:0.018
 HOH
 4.617
 N
 O
6zvq 1 Q15796 100.0 1e-169 X-RAY
 2021-06-09 LEU A:209 A:449 2.0 0.012 H -56.7 -44.1 0.0 0.0 0.012 A:Q15796:0.012
 TAR
HOH
 7.521
8.085
 CD2
CD1
 O2
O
6m64 1 Q15796 99.51 5e-152 X-RAY
 2020-11-25 LEU A:190 A:449 5.0 0.029 H -58.8 -42.3 0.0 0.0 0.029 E:Q15796:0.029
 HOH
 6.745
 CD2
 O
LEU C:190 C:449 3.0 0.018 H -56.7 -43.5 0.0 0.0 0.018 A:Q15796:0.018
 HOH
 7.487
 N
 O
LEU E:190 E:449 5.0 0.029 H -61.0 -41.5 0.0 0.0 0.029 C:Q15796:0.029
 HOH
 6.606
 CD2
 O
7co1 1 Q15796 99.51 5e-152 X-RAY
 2020-11-25 LEU A:190 A:449 4.0 0.024 H -62.2 -39.2 0.0 0.0 0.024 E:Q15796:0.024
LEU C:190 C:449 3.0 0.018 H -62.4 -39.2 0.0 0.0 0.018 A:Q15796:0.018
LEU E:190 E:449 6.0 0.035 H -62.8 -39.8 0.0 0.0 0.035 C:Q15796:0.035
1mk2 1 P84022 96.6 8e-150 X-RAY
 2002-10-16 LEU A:188 A:406 0.0 0.0 H -71.7 -34.8 0.0 0.0 0.0
1u7v 1 Q15796 100.0 2e-147 X-RAY
 2004-09-28 LEU A:180 A:449 2.0 0.012 H -63.4 -49.7 0.0 0.0 0.012 C:Q13485:0.012
LEU B:180 C:449 3.0 0.018 H -60.3 -46.2 0.0 0.0 0.018 A:Q15796:0.018
5xod 1 Q15796 100.0 2e-146 X-RAY
 2018-03-28 LEU A:190 A:449 3.0 0.018 H -61.6 -35.9 0.0 0.0 0.018 A:Q15796:0.018
 HOH
 7.451
 N
 O
5zoj 1 Q15796 100.0 3e-146 X-RAY
 2018-10-10 LEU A:191 A:449 7.0 0.041 H -60.1 -38.6 0.0 0.0 0.041 C:Q15796:0.041
LEU B:191 B:449 2.0 0.012 H -59.9 -37.7 0.0 0.0 0.012 A:Q15796:0.012
LEU C:191 C:449 2.0 0.012 H -58.1 -37.3 0.0 0.0 0.012 B:Q15796:0.012
1dev 1 Q15796 100.0 7e-146 X-RAY
 2000-01-21 LEU A:189 A:449 4.0 0.024 H -60.1 -41.8 4.0 0.024 0.0
LEU C:189 C:449 3.0 0.018 H -61.5 -39.7 NA NA NA
1u7f 1 P84022 96.97 2e-144 X-RAY
 2004-09-28 LEU A:180 A:407 2.0 0.012 H -62.6 -49.3 0.0 0.0 0.012 B:Q13485:0.012
 HOH
 7.818
 O
 O
LEU C:180 C:407 4.0 0.024 H -56.0 -44.4 0.0 0.0 0.024 A:P84022:0.024
 HOH
 6.844
 O
 O
1mjs 1 P84022 96.95 1e-143 X-RAY
 2002-10-16 LEU A:179 A:406 2.0 0.012 H -60.2 -39.6 2.0 0.012 0.0 HOH
 6.185
 N
 O
5xoc 1 P84022 97.46 2e-143 X-RAY
 2018-03-28 LEU A:190 A:407 3.0 0.018 H -57.9 -38.2 0.0 0.0 0.018 A:P84022:0.018

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15796-f1 1 Q15796 100.0 0.0 LEU A:449 A:449 3.0 0.018 H -60.5 -45.9
af-p84022-f1 1 P84022 83.94 0.0 LEU A:407 A:407 2.0 0.012 H -61.2 -46.2