Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr18 45368277 . A C CCDS11934.1:NM_001003652.3:c.1325cTg>cGg_NP_001003652.1:p.442L>R Homo sapiens SMAD family member 2 (SMAD2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 100.0 1e-169 X-RAY
 2002-02-06 LEU A:202 A:442 3.0 0.018 E -92.6 107.5 3.0 0.018 0.0 HOH
 3.917
 C
 O
6zvq 1 Q15796 100.0 1e-169 X-RAY
 2021-06-09 LEU A:202 A:442 4.0 0.024 E -97.0 113.7 0.0 0.0 0.024 B:P12755:0.024
 TAR
GOL
GOL
HOH
 8.561
6.696
9.476
3.871
 N
C
N
C
 O2
O3
O1
O
6m64 1 Q15796 99.51 5e-152 X-RAY
 2020-11-25 LEU A:183 A:442 3.0 0.018 E -97.2 109.7 3.0 0.018 0.0 HOH
 3.997
 C
 O
LEU C:183 C:442 3.0 0.018 E -97.6 110.0 3.0 0.018 0.0 HOH
 3.957
 C
 O
LEU E:183 E:442 3.0 0.018 E -97.9 108.0 3.0 0.018 0.0 HOH
 3.912
 C
 O
7co1 1 Q15796 99.51 5e-152 X-RAY
 2020-11-25 LEU A:183 A:442 4.0 0.024 E -88.3 106.3 4.0 0.024 0.0
LEU C:183 C:442 3.0 0.018 E -89.0 106.2 3.0 0.018 0.0
LEU E:183 E:442 4.0 0.024 E -89.2 107.0 4.0 0.024 0.0
1mk2 1 P84022 96.6 8e-150 X-RAY
 2002-10-16 LEU A:181 A:399 2.0 0.012 E -76.9 100.3 2.0 0.012 0.0
1u7v 1 Q15796 100.0 2e-147 X-RAY
 2004-09-28 LEU A:173 A:442 4.0 0.024 E -87.9 105.6 4.0 0.024 0.0
LEU B:173 C:442 4.0 0.024 -85.6 108.7 4.0 0.024 0.0
5xod 1 Q15796 100.0 2e-146 X-RAY
 2018-03-28 LEU A:183 A:442 4.0 0.024 E -96.3 109.1 0.0 0.0 0.024 B:P12755:0.024
 HOH
 3.819
 C
 O
5zoj 1 Q15796 100.0 3e-146 X-RAY
 2018-10-10 LEU A:184 A:442 5.0 0.029 E -91.8 105.0 5.0 0.029 0.0
LEU B:184 B:442 3.0 0.018 E -93.6 105.6 3.0 0.018 0.0
LEU C:184 C:442 3.0 0.018 E -92.1 104.4 3.0 0.018 0.0
1dev 1 Q15796 100.0 7e-146 X-RAY
 2000-01-21 LEU A:182 A:442 2.0 0.012 E -77.7 100.3 2.0 0.012 0.0
LEU C:182 C:442 2.0 0.012 E -88.1 99.6 NA NA NA
1u7f 1 P84022 96.97 2e-144 X-RAY
 2004-09-28 LEU A:173 A:400 3.0 0.018 E -92.9 105.5 3.0 0.018 0.0 HOH
 4.449
 CD2
 O
LEU C:173 C:400 4.0 0.024 E -87.6 109.1 4.0 0.024 0.0 HOH
 3.832
 CD2
 O
1mjs 1 P84022 96.95 1e-143 X-RAY
 2002-10-16 LEU A:172 A:399 2.0 0.012 E -86.4 108.9 2.0 0.012 0.0 HOH
 3.471
 CD1
 O
5xoc 1 P84022 97.46 2e-143 X-RAY
 2018-03-28 LEU A:183 A:400 4.0 0.024 E -92.7 109.3 4.0 0.024 0.0 HOH
 6.400
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15796-f1 1 Q15796 100.0 0.0 LEU A:442 A:442 4.0 0.024 E -89.6 104.1
af-p84022-f1 1 P84022 83.94 0.0 LEU A:400 A:400 3.0 0.018 E -87.2 104.2