Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr18 45371774 . T A CCDS11934.1:NM_001003652.3:c.1217tAt>tTt_NP_001003652.1:p.406Y>F Homo sapiens SMAD family member 2 (SMAD2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 100.0 1e-169 X-RAY
 2002-02-06 TYR A:166 A:406 131.0 0.57 H -63.4 -36.8 6.0 0.026 0.544 A:Q15796:0.543
 HOH
 2.600
 OH
 O
6zvq 1 Q15796 100.0 1e-169 X-RAY
 2021-06-09 TYR A:166 A:406 135.0 0.587 H -59.5 -40.7 4.0 0.017 0.57 A:Q15796:0.57
 SO4
TAR
GOL
HOH
 7.260
5.487
6.614
2.239
 CB
OH
CE1
OH
 O2
O1
O3
O
6m64 1 Q15796 99.51 5e-152 X-RAY
 2020-11-25 TYR A:147 A:406 125.0 0.543 H -54.0 -42.1 14.0 0.061 0.482 E:Q15796:0.483
 HOH
 2.611
 OH
 O
TYR C:147 C:406 121.0 0.526 H -55.7 -42.2 9.0 0.039 0.487 A:Q15796:0.487
 HOH
 2.629
 OH
 O
TYR E:147 E:406 113.0 0.491 H -58.3 -36.9 27.0 0.117 0.374 C:Q15796:0.374
 HOH
 2.620
 OH
 O
7co1 1 Q15796 99.51 5e-152 X-RAY
 2020-11-25 TYR A:147 A:406 135.0 0.587 H -59.1 -39.2 8.0 0.035 0.552 E:Q15796:0.552
TYR C:147 C:406 134.0 0.583 H -59.5 -37.7 2.0 0.009 0.574 A:Q15796:0.574
TYR E:147 E:406 140.0 0.609 H -58.6 -38.6 13.0 0.057 0.552 C:Q15796:0.552
1mk2 1 P84022 96.6 8e-150 X-RAY
 2002-10-16 TYR A:145 A:363 135.0 0.587 H -52.3 -18.6 56.0 0.243 0.344 A:P84022:0.343
1u7v 1 Q15796 100.0 2e-147 X-RAY
 2004-09-28 TYR A:137 A:406 137.0 0.596 H -51.3 -36.5 10.0 0.043 0.553 C:Q13485:0.552
TYR B:137 C:406 130.0 0.565 H -63.5 -30.8 9.0 0.039 0.526 A:Q15796:0.526
5xod 1 Q15796 100.0 2e-146 X-RAY
 2018-03-28 TYR A:147 A:406 139.0 0.604 H -60.0 -33.9 14.0 0.061 0.543 A:Q15796:0.543
 HOH
 3.698
 CE1
 O
5zoj 1 Q15796 100.0 3e-146 X-RAY
 2018-10-10 TYR A:148 A:406 126.0 0.548 H -62.8 -44.2 32.0 0.139 0.409 C:Q15796:0.409
TYR B:148 B:406 126.0 0.548 H -66.4 -39.5 12.0 0.052 0.496 A:Q15796:0.496
TYR C:148 C:406 121.0 0.526 H -64.5 -42.3 11.0 0.048 0.478 B:Q15796:0.478
1dev 1 Q15796 100.0 7e-146 X-RAY
 2000-01-21 TYR A:146 A:406 122.0 0.53 H -69.0 -26.4 122.0 0.53 0.0
TYR C:146 C:406 124.0 0.539 H -58.5 -31.2 NA NA NA
1u7f 1 P84022 96.97 2e-144 X-RAY
 2004-09-28 TYR A:137 A:364 141.0 0.613 H -46.7 -40.2 5.0 0.022 0.591 B:Q13485:0.591
 HOH
 5.862
 CE1
 O
TYR C:137 C:364 129.0 0.561 H -54.8 -43.2 10.0 0.043 0.518 A:P84022:0.517
 HOH
 2.510
 OH
 O
1mjs 1 P84022 96.95 1e-143 X-RAY
 2002-10-16 TYR A:136 A:363 116.0 0.504 H -59.4 -30.8 116.0 0.504 0.0 HOH
 3.384
 OH
 O
5xoc 1 P84022 97.46 2e-143 X-RAY
 2018-03-28 TYR A:147 A:364 131.0 0.57 H -59.0 -34.8 21.0 0.091 0.479 A:P84022:0.478
 HOH
 2.300
 OH
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15796-f1 1 Q15796 100.0 0.0 TYR A:406 A:406 125.0 0.543 H -58.1 -39.3
af-p84022-f1 1 P84022 83.94 0.0 TYR A:364 A:364 122.0 0.53 H -59.4 -40.2