Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr18 45375021 . C A CCDS11934.1:NM_001003652.3:c.822tgG>tgT_NP_001003652.1:p.274W>C Homo sapiens SMAD family member 2 (SMAD2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1khx 1 Q15796 100.0 1e-169 X-RAY
 2002-02-06 TRP A:34 A:274 33.0 0.129 S -70.6 -20.2 33.0 0.129 0.0 HOH
 2.802
 O
 O
6zvq 1 Q15796 100.0 1e-169 X-RAY
 2021-06-09 TRP A:34 A:274 33.0 0.129 S -72.8 -25.6 23.0 0.09 0.039 B:P12755:0.039
 GOL
TAR
HOH
 3.257
9.170
2.594
 CB
N
O
 C3
H3
O
6m64 1 Q15796 99.51 5e-152 X-RAY
 2020-11-25 TRP A:15 A:274 24.0 0.094 S -74.6 -23.7 24.0 0.094 0.0 HOH
 2.708
 O
 O
TRP C:15 C:274 26.0 0.102 S -77.3 -22.2 26.0 0.102 0.0 HOH
 2.740
 O
 O
TRP E:15 E:274 30.0 0.118 S -74.6 -23.2 30.0 0.118 0.0 HOH
 2.724
 O
 O
7co1 1 Q15796 99.51 5e-152 X-RAY
 2020-11-25 TRP A:15 A:274 28.0 0.11 S -77.1 -10.7 28.0 0.11 0.0
TRP C:15 C:274 29.0 0.114 S -76.6 -10.7 29.0 0.114 0.0
TRP E:15 E:274 29.0 0.114 S -76.5 -11.0 29.0 0.114 0.0
1mk2 1 P84022 96.6 8e-150 X-RAY
 2002-10-16 TRP A:13 A:231 7.0 0.027 -71.2 -13.9 7.0 0.027 0.0
1u7v 1 Q15796 100.0 2e-147 X-RAY
 2004-09-28 TRP A:5 A:274 19.0 0.075 S -76.1 -7.9 19.0 0.075 0.0
TRP B:5 C:274 29.0 0.114 S 38.1 -15.9 29.0 0.114 0.0
5xod 1 Q15796 100.0 2e-146 X-RAY
 2018-03-28 TRP A:15 A:274 38.0 0.149 S -80.0 -13.7 27.0 0.106 0.043 B:P12755:0.043
 HOH
 2.705
 O
 O
5zoj 1 Q15796 100.0 3e-146 X-RAY
 2018-10-10 TRP A:16 A:274 28.0 0.11 S -70.4 -18.8 28.0 0.11 0.0
TRP B:16 B:274 38.0 0.149 S -69.9 -18.8 38.0 0.149 0.0
TRP C:16 C:274 33.0 0.129 S -70.3 -16.9 33.0 0.129 0.0
1dev 1 Q15796 100.0 7e-146 X-RAY
 2000-01-21 TRP A:14 A:274 9.0 0.035 -58.3 -27.7 9.0 0.035 0.0
TRP C:14 C:274 7.0 0.027 -66.5 -22.7 NA NA NA
1u7f 1 P84022 96.97 2e-144 X-RAY
 2004-09-28 TRP A:5 A:232 20.0 0.078 S -77.1 -11.4 20.0 0.078 0.0 HOH
 4.850
 C
 O
TRP C:5 C:232 27.0 0.106 S 39.9 -18.6 27.0 0.106 0.0 HOH
 4.136
 O
 O
1mjs 1 P84022 96.95 1e-143 X-RAY
 2002-10-16 TRP A:4 A:231 11.0 0.043 S -67.9 -17.9 11.0 0.043 0.0 HOH
 2.486
 O
 O
5xoc 1 P84022 97.46 2e-143 X-RAY
 2018-03-28 TRP A:15 A:232 16.0 0.063 -78.3 -21.1 16.0 0.063 0.0 HOH
 7.613
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q15796-f1 1 Q15796 100.0 0.0 TRP A:274 A:274 15.0 0.059 S -75.5 -26.6
af-p84022-f1 1 P84022 83.94 0.0 TRP A:232 A:232 16.0 0.063 S -75.3 -28.8