Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr18 51809277 . T A CCDS11954.2:NM_007195.2:c.867ttT>ttA_NP_009126.2:p.289F>L Homo sapiens DNA polymerase iota (POLI), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5kt6 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 PHE C:289 A:289 43.0 0.205 S -71.8 149.8 43.0 0.205 0.0
5kt7 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 PHE C:289 A:264 42.0 0.2 S -70.7 155.4 42.0 0.2 0.0
5kt4 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 PHE C:289 A:289 44.0 0.21 S -64.3 157.0 44.0 0.21 0.0
5kt5 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 PHE C:289 A:289 45.0 0.214 S -63.6 157.5 45.0 0.214 0.0
2dpi 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 PHE C:264 A:264 48.0 0.229 S -78.4 159.9 48.0 0.229 0.0 HOH
 3.653
 CD1
 O
2dpj 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 PHE C:264 A:264 49.0 0.233 S -72.7 159.1 49.0 0.233 0.0 HOH
 3.458
 CD1
 O
2fll 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-12 PHE C:264 A:264 48.0 0.229 S -68.1 149.9 48.0 0.229 0.0 HOH
 3.591
 CD1
 O
2fln 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 PHE C:264 A:264 46.0 0.219 S -62.2 163.1 46.0 0.219 0.0 HOH
 3.588
 CD1
 O
2flp 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 PHE C:264 A:264 46.0 0.219 S -74.2 156.3 46.0 0.219 0.0 HOH
 3.632
 N
 O
3epg 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 PHE A:264 A:264 45.0 0.214 S -93.2 145.0 45.0 0.214 0.0
3epi 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 PHE A:264 A:264 48.0 0.229 S -62.5 145.1 48.0 0.229 0.0
3g6v 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 PHE A:264 A:264 47.0 0.224 S -81.4 151.8 47.0 0.224 0.0 HOH
 3.694
 CD1
 O
3g6x 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 PHE A:264 A:264 45.0 0.214 S -81.0 151.0 45.0 0.214 0.0 HOH
 3.379
 CD1
 O
3g6y 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 PHE A:264 A:264 45.0 0.214 S -77.3 155.8 45.0 0.214 0.0 HOH
 3.701
 CD1
 O
3gv5 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 PHE A:264 B:264 45.0 0.214 S -82.3 143.1 45.0 0.214 0.0 HOH
 6.592
 O
 O
PHE D:264 D:264 58.0 0.276 S -81.5 139.2 NA NA NA
3gv7 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 PHE A:264 B:264 47.0 0.224 S -71.7 144.9 47.0 0.224 0.0 HOH
 2.598
 O
 O
3gv8 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 PHE A:264 B:264 48.0 0.229 S -76.4 149.2 48.0 0.229 0.0 HOH
 2.674
 O
 O
3ngd 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 PHE C:264 A:264 48.0 0.229 S -68.1 158.1 48.0 0.229 0.0
3osn 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 PHE C:264 A:264 44.0 0.21 S -74.7 150.0 44.0 0.21 0.0 HOH
 2.238
 O
 O
3q8p 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 PHE A:264 B:264 47.0 0.224 S -72.5 148.1 47.0 0.224 0.0 HOH
 2.744
 O
 O
3q8q 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 PHE A:264 B:264 45.0 0.214 S -75.1 150.2 45.0 0.214 0.0 HOH
 3.213
 CD1
 O
3q8r 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 PHE A:264 B:264 47.0 0.224 S -71.0 162.4 47.0 0.224 0.0 HOH
 3.411
 CE1
 O
3q8s 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 PHE A:264 B:264 44.0 0.21 S -66.6 149.8 44.0 0.21 0.0 HOH
 3.445
 CD1
 O
4ebc 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 PHE A:264 A:264 50.0 0.238 S -61.2 162.2 50.0 0.238 0.0 HOH
 8.803
 CD1
 O
4ebd 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 PHE A:264 A:264 43.0 0.205 S -68.7 162.2 43.0 0.205 0.0 HOH
 2.975
 CD1
 O
4ebe 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 PHE A:264 A:264 50.0 0.238 S -74.8 159.0 50.0 0.238 0.0 HOH
 3.508
 C
 O
4eyh 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 PHE A:264 B:264 42.0 0.2 S -62.3 156.4 42.0 0.2 0.0
4eyi 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 PHE A:264 B:264 44.0 0.21 S -70.3 161.1 44.0 0.21 0.0 HOH
 3.064
 O
 O
4fs1 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 PHE C:264 A:264 47.0 0.224 S -79.8 157.4 47.0 0.224 0.0 HOH
 3.614
 CD1
 O
4fs2 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 PHE C:264 A:264 45.0 0.214 S -83.0 155.3 45.0 0.214 0.0 HOH
 3.285
 CD2
 O
5kt2 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 PHE C:264 A:289 47.0 0.224 S -76.5 156.5 47.0 0.224 0.0
5kt3 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 PHE C:264 A:289 45.0 0.214 S -77.4 161.0 45.0 0.214 0.0
5ulw 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 PHE C:264 A:264 50.0 0.238 S -62.7 160.9 50.0 0.238 0.0 HOH
 3.354
 CD2
 O
5ulx 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 PHE C:264 A:264 48.0 0.229 S -68.0 154.2 48.0 0.229 0.0 HOH
 3.486
 N
 O
2alz 3 Q9UNA4 100.0 0.0 X-RAY
 2005-10-25 PHE C:240 A:264 44.0 0.21 S -68.8 164.9 44.0 0.21 0.0 HOH
 3.582
 CD1
 O
3h4b 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 PHE A:240 A:264 45.0 0.214 S -65.8 156.4 45.0 0.214 0.0 HOH
 3.505
 CD1
 O
3h4d 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 PHE A:240 A:264 45.0 0.214 S -65.5 160.9 45.0 0.214 0.0 HOH
 3.527
 CD1
 O
3h40 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 PHE A:239 A:264 47.0 0.224 S -68.7 160.0 47.0 0.224 0.0 HOH
 3.639
 CD1
 O
1t3n 3 Q9UNA4 100.0 0.0 X-RAY
 2004-07-20 PHE C:238 A:264 41.0 0.195 S -53.8 153.8 41.0 0.195 0.0 HOH
 3.025
 N
 O
PHE D:238 B:684 46.0 0.219 S -63.7 153.7 46.0 0.219 0.0 HOH
 2.930
 O
 O
1zet 3 21619716 100.0 0.0 X-RAY
 2005-07-19 PHE C:238 A:264 38.0 0.181 S -63.1 150.9 38.0 0.181 0.0 HOH
 3.188
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9una4-f1 1 Q9UNA4 100.0 0.0 PHE A:289 A:289 45.0 0.214 S -65.6 146.3