Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr18 51813677 . A C CCDS11954.2:NM_007195.2:c.1094cAt>cCt_NP_009126.2:p.365H>P Homo sapiens DNA polymerase iota (POLI), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5kt6 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 HIS C:365 A:365 66.0 0.338 -115.8 0.0 66.0 0.338 0.0
5kt7 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 HIS C:365 A:340 61.0 0.313 E -116.1 20.7 61.0 0.313 0.0
5kt4 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 HIS C:365 A:365 74.0 0.379 E -113.2 11.5 74.0 0.379 0.0
5kt5 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 HIS C:365 A:365 75.0 0.385 E -107.9 12.0 75.0 0.385 0.0
2dpi 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 HIS C:340 A:340 70.0 0.359 E -110.7 -0.1 70.0 0.359 0.0 DC
DC
DT
HOH
 9.432
7.217
6.727
4.860
 CB
O
O
O
 O3'
OP1
OP2
O
2dpj 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 HIS C:340 A:340 75.0 0.385 E -106.2 -1.0 75.0 0.385 0.0 DC
DC
DT
HOH
 9.404
7.143
6.663
4.847
 CB
O
O
O
 O3'
OP1
OP2
O
2fll 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-12 HIS C:340 A:340 71.0 0.364 E -110.7 7.5 71.0 0.364 0.0 DC
DT
HOH
 7.988
7.037
9.986
 O
O
ND1
 OP1
OP2
O
2fln 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 HIS C:340 A:340 74.0 0.379 E -93.2 1.8 74.0 0.379 0.0 DC
DC
DT
 9.773
7.627
6.696
 CB
CB
O
 O3'
OP1
OP2
2flp 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 HIS C:340 A:340 61.0 0.313 E -108.2 0.8 61.0 0.313 0.0 DC
DT
HOH
 8.297
7.007
4.477
 O
O
O
 OP1
OP2
O
3epg 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 HIS A:340 A:340 59.0 0.303 E -112.4 15.1 59.0 0.303 0.0 DC
DC
DT
NA
HOH
 9.297
6.846
6.555
8.972
9.102
 O
O
O
ND1
O
 O3'
OP1
OP2
NA
O
3epi 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 HIS A:340 A:340 59.0 0.303 E -93.9 -2.2 59.0 0.303 0.0 DC
DT
HOH
 7.662
6.786
7.061
 CB
O
CB
 OP1
OP2
O
3g6v 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 HIS A:340 A:340 66.0 0.338 E -104.9 4.1 66.0 0.338 0.0
3g6x 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 HIS A:340 A:340 64.0 0.328 E -115.8 3.4 64.0 0.328 0.0
3g6y 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 HIS A:340 A:340 63.0 0.323 E -111.2 0.9 63.0 0.323 0.0 HOH
 7.288
 O
 O
3gv5 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 HIS A:340 B:340 52.0 0.267 E -105.3 -8.0 52.0 0.267 0.0 DG
DT
HOH
 8.078
7.121
4.487
 O
O
O
 O3'
OP2
O
HIS D:340 D:340 58.0 0.297 E -108.6 -6.0 NA NA NA
3gv7 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 HIS A:340 B:340 63.0 0.323 E -104.6 -6.3 63.0 0.323 0.0 HOH
 4.804
 CE1
 O
3gv8 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 HIS A:340 B:340 72.0 0.369 E -112.2 -4.5 72.0 0.369 0.0 HOH
 6.963
 CB
 O
3ngd 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 HIS C:340 A:340 66.0 0.338 E -111.8 -0.9 66.0 0.338 0.0 HOH
 9.600
 CD2
 O
3osn 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 HIS C:340 A:340 59.0 0.303 E -113.3 -0.9 59.0 0.303 0.0 HOH
 5.014
 CB
 O
3q8p 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 HIS A:340 B:340 56.0 0.287 E -106.1 -3.6 56.0 0.287 0.0 HOH
 2.589
 O
 O
3q8q 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 HIS A:340 B:340 58.0 0.297 E -106.3 -2.2 58.0 0.297 0.0 HOH
 3.287
 CD2
 O
3q8r 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 HIS A:340 B:340 58.0 0.297 E -120.4 9.9 58.0 0.297 0.0 HOH
 6.886
 CB
 O
3q8s 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 HIS A:340 B:340 53.0 0.272 E -116.9 -4.4 53.0 0.272 0.0 HOH
 3.010
 O
 O
4ebc 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 HIS A:340 A:340 64.0 0.328 -121.4 19.2 64.0 0.328 0.0
4ebd 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 HIS A:340 A:340 59.0 0.303 E -115.5 10.4 59.0 0.303 0.0
4ebe 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 HIS A:340 A:340 63.0 0.323 E -122.7 3.2 63.0 0.323 0.0 HOH
 2.570
 NE2
 O
4eyh 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 HIS A:340 B:340 75.0 0.385 E -116.7 3.3 75.0 0.385 0.0 HOH
 8.665
 O
 O
4eyi 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 HIS A:340 B:340 63.0 0.323 E -103.8 7.4 63.0 0.323 0.0 HOH
 8.853
 O
 O
4fs1 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 HIS C:340 A:340 81.0 0.415 E -118.3 7.0 81.0 0.415 0.0 HOH
 9.522
 CD2
 O
4fs2 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 HIS C:340 A:340 56.0 0.287 E -122.4 -0.5 56.0 0.287 0.0 HOH
 7.297
 O
 O
5kt2 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 HIS C:340 A:365 62.0 0.318 E -117.8 7.0 62.0 0.318 0.0
5kt3 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 HIS C:340 A:365 62.0 0.318 E -112.8 11.8 62.0 0.318 0.0
5ulw 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 HIS C:340 A:340 60.0 0.308 E -109.0 12.0 60.0 0.308 0.0
5ulx 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 HIS C:340 A:340 61.0 0.313 E -105.9 6.0 61.0 0.313 0.0 HOH
 7.310
 CE1
 O
2alz 3 Q9UNA4 100.0 0.0 X-RAY
 2005-10-25 HIS C:316 A:340 72.0 0.369 E -106.4 12.9 72.0 0.369 0.0 DC
DC
DT
 9.439
7.145
6.548
 O
O
O
 O3'
OP1
OP2
3h4b 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 HIS A:316 A:340 64.0 0.328 E -118.2 29.2 64.0 0.328 0.0 HOH
 7.577
 O
 O
3h4d 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 HIS A:316 A:340 65.0 0.333 E -116.4 18.7 65.0 0.333 0.0 HOH
 5.388
 ND1
 O
3h40 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 HIS A:315 A:340 69.0 0.354 E -110.3 19.0 69.0 0.354 0.0 HOH
 7.453
 N
 O
1t3n 3 Q9UNA4 100.0 0.0 X-RAY
 2004-07-20 HIS C:314 A:340 66.0 0.338 -86.4 -1.8 66.0 0.338 0.0 DC
DT
HOH
 7.948
7.427
9.062
 O
O
CE1
 OP1
OP2
O
HIS D:314 B:760 76.0 0.39 S -99.7 12.7 76.0 0.39 0.0 DG
DG
DA
HOH
 9.978
7.258
5.245
9.057
 O
O
O
CE1
 O3'
O3'
OP2
O
1zet 3 21619716 100.0 0.0 X-RAY
 2005-07-19 HIS C:314 A:340 42.0 0.215 -140.8 19.1 42.0 0.215 0.0 DG
DG
DA
HOH
 9.772
7.268
4.899
9.853
 O
O
O
O
 O3'
O3'
OP2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9una4-f1 1 Q9UNA4 100.0 0.0 HIS A:365 A:365 61.0 0.313 E -104.4 -8.8