Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr18 | 51813705 | . | T | A | CCDS11954.2:NM_007195.2:c.1122taT>taA_NP_009126.2:p.374Y>* | Homo sapiens DNA polymerase iota (POLI), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5kt6 | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2016-08-31 | TYR | C:374 | A:374 | 127.0 | 0.552 | -86.9 | 160.1 | 127.0 | 0.552 | 0.0 |
DT |
5.967 |
CA |
C7 |
|||
| 5kt7 | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2016-08-31 | TYR | C:374 | A:349 | 87.0 | NA | -77.6 | 360.0 | 87.0 | NA | NA | |||||||
| 5kt4 | 3 | Q9UNA4 | 99.78 | 0.0 |
X-RAY |
2016-08-31 | TYR | C:374 | A:374 | 89.0 | NA | -63.1 | 360.0 | 89.0 | NA | NA | |||||||
| 5kt5 | 3 | Q9UNA4 | 99.78 | 0.0 |
X-RAY |
2016-08-31 | TYR | C:374 | A:374 | 37.0 | NA | -67.9 | 144.0 | 37.0 | NA | NA | |||||||
| 2dpi | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-07-04 | TYR | C:349 | A:349 | 78.0 | NA | -138.4 | 118.1 | 78.0 | NA | NA | |||||||
| 2dpj | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-07-04 | TYR | C:349 | A:349 | 78.0 | NA | -125.3 | 152.4 | 78.0 | NA | NA |
HOH |
6.635 |
N |
O |
|||
| 2fll | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | TYR | C:349 | A:349 | 70.0 | NA | -90.8 | 106.6 | 70.0 | NA | NA | |||||||
| 2fln | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-12-05 | TYR | C:349 | A:349 | 132.0 | NA | -56.8 | 360.0 | 132.0 | NA | NA | |||||||
| 2flp | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-12-05 | TYR | C:349 | A:349 | 153.0 | NA | -113.2 | 360.0 | 153.0 | NA | NA | |||||||
| 3epg | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2008-12-16 | TYR | A:349 | A:349 | 49.0 | NA | -116.0 | 133.1 | 49.0 | NA | NA | |||||||
| 3epi | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2008-12-16 | TYR | A:349 | A:349 | 196.0 | 0.852 | -99.2 | 153.4 | 196.0 | 0.852 | 0.0 |
2EG HOH |
9.856 5.837 |
O CA |
OP2 O |
|||
| 3g6v | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-05-12 | TYR | A:349 | A:349 | 46.0 | NA | -75.0 | -158.7 | 46.0 | NA | NA |
DT HOH |
9.752 3.143 |
O CB |
O3' O |
|||
| 3g6x | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-05-12 | TYR | A:349 | A:349 | 83.0 | NA | -159.1 | 145.1 | 83.0 | NA | NA |
3DR |
9.040 |
CB |
OP1 |
|||
| 3g6y | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-05-12 | TYR | A:349 | A:349 | 75.0 | NA | -82.3 | -162.2 | 75.0 | NA | NA | |||||||
| 3gv5 | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-06-02 | TYR | A:349 | B:349 | 146.0 | 0.635 | -63.7 | 141.5 | 146.0 | 0.635 | 0.0 |
DT HOH |
9.331 3.441 |
CA CA |
OP1 O |
|||
| TYR | D:349 | D:349 | 131.0 | 0.57 | -100.0 | 142.0 | NA | NA | NA | ||||||||||||||
| 3gv7 | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-06-02 | TYR | A:349 | B:349 | 230.0 | 1.0 | 151.2 | 360.0 | 230.0 | 1.0 | 0.0 |
DA HOH |
9.177 2.705 |
CD2 O |
C5' O |
|||
| 3gv8 | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-06-02 | TYR | A:349 | B:349 | 233.0 | 1.0 | 114.9 | 360.0 | 233.0 | 1.0 | 0.0 |
DA |
8.897 |
CD2 |
C5' |
|||
| 3ngd | 2 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2010-10-20 | TYR | C:349 | A:349 | 95.0 | 0.413 | -55.8 | 125.6 | 95.0 | 0.413 | 0.0 |
HOH |
8.546 |
OH |
O |
|||
| 3osn | 2 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2010-10-20 | TYR | C:349 | A:349 | 37.0 | NA | E | -152.1 | 178.6 | 37.0 | NA | NA | ||||||
| 3q8p | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2011-02-23 | TYR | A:349 | B:349 | 148.0 | 0.643 | -61.3 | 138.9 | 148.0 | 0.643 | 0.0 |
HOH |
4.320 |
CA |
O |
|||
| 3q8q | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2011-02-23 | TYR | A:349 | B:349 | 150.0 | 0.652 | -64.7 | 141.4 | 150.0 | 0.652 | 0.0 |
HOH |
4.065 |
O |
O |
|||
| 3q8r | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2011-02-23 | TYR | A:349 | B:349 | 53.0 | NA | -52.7 | 156.6 | 53.0 | NA | NA |
HOH |
2.847 |
CB |
O |
|||
| 3q8s | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2011-02-23 | TYR | A:349 | B:349 | 144.0 | 0.626 | -64.7 | 128.0 | 144.0 | 0.626 | 0.0 |
HOH |
2.875 |
O |
O |
|||
| 4ebc | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-06-13 | TYR | A:349 | A:349 | 199.0 | 0.865 | -173.5 | 360.0 | 199.0 | 0.865 | 0.0 |
DC DT |
7.399 9.751 |
CE2 CD2 |
OP1 OP2 |
|||
| 4ebd | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-06-13 | TYR | A:349 | A:349 | 221.0 | 0.961 | 64.5 | 360.0 | 221.0 | 0.961 | 0.0 |
DC DT HOH |
5.321 9.548 9.195 |
O C CD2 |
OP1 OP1 O |
|||
| 4ebe | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-06-13 | TYR | A:349 | A:349 | 234.0 | 1.0 | 67.8 | 360.0 | 234.0 | 1.0 | 0.0 |
DC HOH |
6.301 3.377 |
C OH |
OP1 O |
|||
| 4eyh | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2013-01-09 | TYR | A:349 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4eyi | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2013-01-09 | TYR | A:349 | B:349 | 226.0 | 0.983 | -177.2 | 360.0 | 226.0 | 0.983 | 0.0 | |||||||
| 4fs1 | 2 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-08-29 | TYR | C:349 | A:349 | 33.0 | NA | S | -69.9 | 137.8 | 33.0 | NA | NA |
DT |
8.116 |
CA |
O5' |
||
| 4fs2 | 2 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-08-29 | TYR | C:349 | A:349 | 31.0 | NA | -76.5 | 142.8 | 31.0 | NA | NA |
HOH |
9.846 |
O |
O |
|||
| 5kt2 | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2016-08-31 | TYR | C:349 | A:374 | 98.0 | 0.426 | -65.3 | 116.8 | 98.0 | 0.426 | 0.0 | |||||||
| 5kt3 | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2016-08-31 | TYR | C:349 | A:374 | 89.0 | NA | -41.6 | 360.0 | 89.0 | NA | NA |
HOH |
9.330 |
CB |
O |
|||
| 5ulw | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2017-04-19 | TYR | C:349 | A:349 | 52.0 | NA | -56.6 | 139.1 | 52.0 | NA | NA |
HOH |
9.002 |
CA |
O |
|||
| 5ulx | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2017-04-19 | TYR | C:349 | A:349 | 39.0 | NA | -58.0 | 116.6 | 39.0 | NA | NA |
HOH |
9.867 |
CB |
O |
|||
| 2alz | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2005-10-25 | TYR | C:325 | A:349 | 82.0 | NA | -138.0 | 155.6 | 82.0 | NA | NA | |||||||
| 3h4b | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-07-21 | TYR | A:325 | A:349 | 50.0 | NA | -77.0 | 149.9 | 50.0 | NA | NA |
HOH |
5.837 |
CB |
O |
|||
| 3h4d | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-07-21 | TYR | A:325 | A:349 | 69.0 | NA | -79.4 | 141.3 | 69.0 | NA | NA |
HOH |
9.436 |
CB |
O |
|||
| 3h40 | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-07-21 | TYR | A:324 | A:349 | 68.0 | NA | -83.8 | 142.7 | 68.0 | NA | NA |
HOH |
7.286 |
CB |
O |
|||
| 1t3n | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2004-07-20 | TYR | C:323 | A:349 | 90.0 | NA | -80.5 | 124.7 | 90.0 | NA | NA | |||||||
| TYR | D:323 | B:769 | 16.0 | NA | -115.8 | 150.8 | 16.0 | NA | NA |
DG HOH |
9.679 8.579 |
N CB |
OP1 O |
||||||||||
| 1zet | 3 | 21619716 | 100.0 | 0.0 |
X-RAY |
2005-07-19 | TYR | C:323 | A:349 | 168.0 | 0.73 | S | -72.0 | 103.1 | 168.0 | 0.73 | 0.0 | ||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q9una4-f1 | 1 | Q9UNA4 | 100.0 | 0.0 | TYR | A:374 | A:374 | 143.0 | 0.622 | -70.4 | 134.2 | ||