Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr18 | 51813720 | . | C | A | CCDS11954.2:NM_007195.2:c.1137caC>caA_NP_009126.2:p.379H>Q | Homo sapiens DNA polymerase iota (POLI), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5kt6 | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2016-08-31 | HIS | C:379 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 5kt7 | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2016-08-31 | HIS | C:379 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 5kt4 | 3 | Q9UNA4 | 99.78 | 0.0 |
X-RAY |
2016-08-31 | HIS | C:379 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 5kt5 | 3 | Q9UNA4 | 99.78 | 0.0 |
X-RAY |
2016-08-31 | HIS | C:379 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2dpi | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-07-04 | HIS | C:354 | A:354 | 101.0 | NA | S | -49.9 | -27.7 | 101.0 | NA | NA |
DG DA DC DT EDA |
8.639 8.407 9.965 7.084 9.129 |
C O O O O |
OP2 OP2 N4 O4 C10 |
||
| 2dpj | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-07-04 | HIS | C:354 | A:354 | 102.0 | NA | S | -49.0 | -25.8 | 102.0 | NA | NA |
DG DA DT EDA |
8.592 8.344 7.163 9.542 |
C O O O |
OP2 OP2 C7 C10 |
||
| 2fll | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | HIS | C:354 | A:354 | 79.0 | NA | T | 15.9 | -71.2 | 79.0 | NA | NA |
DG DT DA |
8.381 5.679 8.786 |
O CB CB |
OP2 O5' OP1 |
||
| 2fln | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-12-05 | HIS | C:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2flp | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-12-05 | HIS | C:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3epg | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2008-12-16 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3epi | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2008-12-16 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3g6v | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-05-12 | HIS | A:354 | A:354 | 109.0 | NA | S | -32.3 | -26.2 | 109.0 | NA | NA |
DG DA DC DT |
8.220 7.836 9.982 3.946 |
C O O O |
OP2 OP2 OP2 C7 |
||
| 3g6x | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-05-12 | HIS | A:354 | A:354 | 101.0 | NA | S | 52.2 | -100.0 | 101.0 | NA | NA |
DG DA HOH |
8.572 7.993 5.333 |
C CB N |
OP2 OP2 O |
||
| 3g6y | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-05-12 | HIS | A:354 | A:354 | 104.0 | NA | -40.7 | -27.9 | 104.0 | NA | NA |
DG DA HOH |
8.432 8.579 9.886 |
C C O |
OP2 OP2 O |
|||
| 3gv5 | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-06-02 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| HIS | D:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 3gv7 | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-06-02 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3gv8 | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-06-02 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3ngd | 2 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2010-10-20 | HIS | C:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3osn | 2 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2010-10-20 | HIS | C:354 | A:354 | 96.0 | NA | -154.0 | 152.0 | 96.0 | NA | NA |
DG DG DA HOH |
9.864 7.966 9.586 8.447 |
CB CB CB O |
O3' OP1 OP2 O |
|||
| 3q8p | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2011-02-23 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3q8q | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2011-02-23 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3q8r | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2011-02-23 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 3q8s | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2011-02-23 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4ebc | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-06-13 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4ebd | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-06-13 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4ebe | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-06-13 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4eyh | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2013-01-09 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4eyi | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2013-01-09 | HIS | A:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4fs1 | 2 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-08-29 | HIS | C:354 | A:354 | 82.0 | NA | S | -98.1 | 63.5 | 82.0 | NA | NA |
DG |
8.307 |
O |
OP2 |
||
| 4fs2 | 2 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-08-29 | HIS | C:354 | A:354 | 103.0 | NA | -74.0 | 112.2 | 103.0 | NA | NA |
DG DG DA HOH |
8.737 6.633 8.090 8.612 |
CB CB CB C |
O3' OP1 OP2 O |
|||
| 5kt2 | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2016-08-31 | HIS | C:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 5kt3 | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2016-08-31 | HIS | C:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 5ulw | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2017-04-19 | HIS | C:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 5ulx | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2017-04-19 | HIS | C:354 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2alz | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2005-10-25 | HIS | C:330 | A:354 | 107.0 | NA | S | 54.3 | -25.5 | 107.0 | NA | NA |
DT DG DG DA |
9.217 9.028 8.780 8.369 |
O O C O |
C2' N2 OP2 OP2 |
||
| 3h4b | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-07-21 | HIS | A:330 | A:354 | 107.0 | NA | S | -59.3 | -0.2 | 107.0 | NA | NA |
DG DA DC DT BRU HOH |
8.778 8.004 9.838 7.163 8.354 5.494 |
C O O O O O |
OP1 OP2 C5 O5' BR O |
||
| 3h4d | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-07-21 | HIS | A:330 | A:354 | 108.0 | NA | S | -61.6 | -7.4 | 108.0 | NA | NA |
DG DA DC DT BRU |
8.850 8.203 9.929 6.362 8.219 |
O O O O O |
OP2 OP2 C5 O5' BR |
||
| 3h40 | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-07-21 | HIS | A:329 | A:354 | 110.0 | NA | S | -64.5 | -0.4 | 110.0 | NA | NA |
DG DA DC DT BRU |
9.029 8.253 9.798 6.301 8.197 |
O O O O O |
OP2 OP2 C5 O5' BR |
||
| 1t3n | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2004-07-20 | HIS | C:328 | A:354 | 64.0 | NA | 67.0 | 30.5 | 64.0 | NA | NA |
DC |
9.646 |
O |
OP2 |
|||
| HIS | D:328 | B:774 | 62.0 | NA | -125.6 | 156.4 | 62.0 | NA | NA |
DA DG DG DA DC DC HOH |
9.148 7.353 5.170 5.136 8.104 9.141 4.450 |
CB O O O O CB O |
N1 O3' OP2 OP2 C5 N4 O |
||||||||||
| 1zet | 3 | 21619716 | 100.0 | 0.0 |
X-RAY |
2005-07-19 | HIS | C:328 | A:354 | 135.0 | 0.692 | T | -108.3 | 41.2 | 135.0 | 0.692 | 0.0 |
DA DG DG DG DA DC DC DOC TTP HOH |
5.124 7.738 8.741 8.597 8.179 7.839 8.457 7.611 7.670 3.808 |
NE2 CD2 CD2 O O O CD2 CD2 NE2 NE2 |
N6 O6 O6 C5' C8 C5 C5 N4 O4 O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q9una4-f1 | 1 | Q9UNA4 | 100.0 | 0.0 | HIS | A:379 | A:379 | 139.0 | 0.713 | -76.0 | 86.0 | ||