Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr18 | 51813737 | . | G | A | CCDS11954.2:NM_007195.2:c.1154cGt>cAt_NP_009126.2:p.385R>H | Homo sapiens DNA polymerase iota (POLI), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 5kt6 | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2016-08-31 | ARG | C:385 | A:385 | 95.0 | 0.422 | E | -134.5 | 132.7 | 95.0 | 0.422 | 0.0 |
DA DG |
3.111 3.712 |
CD NH1 |
OP1 OP1 |
||
| 5kt7 | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2016-08-31 | ARG | C:385 | A:360 | 90.0 | 0.4 | E | -132.8 | 136.7 | 90.0 | 0.4 | 0.0 |
DA DG |
3.083 3.796 |
CA NH1 |
OP2 OP1 |
||
| 5kt4 | 3 | Q9UNA4 | 99.78 | 0.0 |
X-RAY |
2016-08-31 | ARG | C:385 | A:385 | 87.0 | 0.387 | E | -133.6 | 129.5 | 87.0 | 0.387 | 0.0 |
DA DG |
3.237 4.037 |
CA NH2 |
OP2 OP1 |
||
| 5kt5 | 3 | Q9UNA4 | 99.78 | 0.0 |
X-RAY |
2016-08-31 | ARG | C:385 | A:385 | 91.0 | 0.404 | E | -128.4 | 133.8 | 91.0 | 0.404 | 0.0 |
DA DG |
3.261 4.137 |
CA NH1 |
OP2 OP1 |
||
| 2dpi | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-07-04 | ARG | C:360 | A:360 | 102.0 | 0.453 | E | -121.3 | 131.3 | 102.0 | 0.453 | 0.0 |
DA DG DC DT HOH |
4.545 5.038 9.380 5.253 8.666 |
NH1 NH2 C CA N |
C4' OP1 O3' O3' O |
||
| 2dpj | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-07-04 | ARG | C:360 | A:360 | 103.0 | 0.458 | E | -132.0 | 122.0 | 103.0 | 0.458 | 0.0 |
DA DG DC DT HOH |
3.757 4.963 9.309 5.324 5.156 |
CD NH2 C CD NH2 |
O5' OP1 O3' O3' O |
||
| 2fll | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-12-12 | ARG | C:360 | A:360 | 102.0 | 0.453 | E | -128.6 | 112.2 | 102.0 | 0.453 | 0.0 |
DA DG DC DT |
3.895 3.795 9.341 4.700 |
NH1 NH2 C CA |
O5' OP1 O3' O3' |
||
| 2fln | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-12-05 | ARG | C:360 | A:360 | 89.0 | 0.396 | E | -104.5 | 102.6 | 89.0 | 0.396 | 0.0 |
DA DG DC DT HOH |
3.343 3.779 9.004 4.520 9.245 |
NH1 NH2 C C N |
O5' OP1 O3' O3' O |
||
| 2flp | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2006-12-05 | ARG | C:360 | A:360 | 95.0 | 0.422 | E | -133.7 | 131.7 | 95.0 | 0.422 | 0.0 |
DA DG DG DC DT HOH |
3.909 3.285 9.962 9.287 4.598 7.588 |
NH1 NH2 NH2 C CA C |
O3' OP1 OP2 O3' O3' O |
||
| 3epg | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2008-12-16 | ARG | A:360 | A:360 | 96.0 | 0.427 | E | -121.8 | 159.5 | 96.0 | 0.427 | 0.0 |
DA DG DC DT |
3.062 3.690 9.523 5.243 |
CA NH2 C C |
OP2 OP1 O3' O3' |
||
| 3epi | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2008-12-16 | ARG | A:360 | A:360 | 89.0 | 0.396 | E | -127.2 | 134.6 | 89.0 | 0.396 | 0.0 |
DA DG DC DT |
3.519 4.518 9.503 5.147 |
CA NH2 C CA |
OP1 OP1 O3' O3' |
||
| 3g6v | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-05-12 | ARG | A:360 | A:360 | 87.0 | 0.387 | E | -113.5 | 124.7 | 87.0 | 0.387 | 0.0 |
DA DG HOH |
4.025 4.043 9.893 |
NH1 NH1 N |
C3' OP1 O |
||
| 3g6x | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-05-12 | ARG | A:360 | A:360 | 107.0 | 0.476 | E | -121.4 | 131.1 | 107.0 | 0.476 | 0.0 |
DA DG HOH |
3.820 3.136 9.081 |
NH2 NH2 N |
O3' OP1 O |
||
| 3g6y | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-05-12 | ARG | A:360 | A:360 | 96.0 | 0.427 | E | -124.0 | 130.0 | 96.0 | 0.427 | 0.0 |
DA DG HOH |
3.646 4.522 9.879 |
NH1 NH1 C |
C5' OP1 O |
||
| 3gv5 | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-06-02 | ARG | A:360 | B:360 | 95.0 | 0.422 | E | -93.9 | 151.4 | 95.0 | 0.422 | 0.0 |
DG DT DG DG HOH |
9.719 5.665 3.438 3.486 3.241 |
C CD CA NH1 CG |
O3' O3' OP2 OP1 O |
||
| ARG | D:360 | D:360 | 97.0 | 0.431 | E | -143.7 | 142.7 | NA | NA | NA | |||||||||||||
| 3gv7 | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-06-02 | ARG | A:360 | B:360 | 85.0 | 0.378 | E | -140.4 | 134.4 | 85.0 | 0.378 | 0.0 |
DA DG HOH |
3.902 4.207 4.029 |
NH1 NH1 NH2 |
C3' OP2 O |
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| 3gv8 | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-06-02 | ARG | A:360 | B:360 | 82.0 | 0.364 | E | -133.6 | 135.0 | 82.0 | 0.364 | 0.0 |
DA DG HOH |
4.228 4.008 3.964 |
NH1 NH1 C |
C3' OP1 O |
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| 3ngd | 2 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2010-10-20 | ARG | C:360 | A:360 | 77.0 | 0.342 | E | -123.8 | 126.0 | 77.0 | 0.342 | 0.0 |
DA DG HOH |
3.280 3.892 9.256 |
CD NH2 N |
OP1 OP1 O |
||
| 3osn | 2 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2010-10-20 | ARG | C:360 | A:360 | 84.0 | 0.373 | E | -137.8 | 137.6 | 84.0 | 0.373 | 0.0 |
DA DG HOH |
3.217 3.985 3.469 |
CA NH1 CD |
OP2 OP2 O |
||
| 3q8p | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2011-02-23 | ARG | A:360 | B:360 | 91.0 | 0.404 | E | -135.0 | 134.6 | 91.0 | 0.404 | 0.0 |
DA DG HOH |
3.245 3.987 3.207 |
CA NH1 NH2 |
OP2 OP2 O |
||
| 3q8q | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2011-02-23 | ARG | A:360 | B:360 | 92.0 | 0.409 | E | -133.6 | 138.3 | 92.0 | 0.409 | 0.0 |
DA DG HOH |
3.245 3.903 3.068 |
CD NH1 CG |
OP1 OP2 O |
||
| 3q8r | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2011-02-23 | ARG | A:360 | B:360 | 95.0 | 0.422 | E | -122.1 | 141.7 | 95.0 | 0.422 | 0.0 |
DA DG HOH |
3.348 3.384 3.240 |
CG NH1 CG |
OP1 OP2 O |
||
| 3q8s | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2011-02-23 | ARG | A:360 | B:360 | 88.0 | 0.391 | E | -142.6 | 131.2 | 88.0 | 0.391 | 0.0 |
DA DG HOH |
3.143 3.891 7.897 |
CD NH1 NH1 |
OP1 OP2 O |
||
| 4ebc | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-06-13 | ARG | A:360 | A:360 | 93.0 | 0.413 | E | -138.0 | 128.3 | 93.0 | 0.413 | 0.0 |
DA DG |
3.033 3.861 |
CA NH1 |
OP1 OP1 |
||
| 4ebd | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-06-13 | ARG | A:360 | A:360 | 92.0 | 0.409 | E | -148.0 | 124.3 | 92.0 | 0.409 | 0.0 |
DA DG HOH |
3.037 3.836 3.280 |
CD NH1 CD |
OP2 OP1 O |
||
| 4ebe | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-06-13 | ARG | A:360 | A:360 | 82.0 | 0.364 | E | -138.1 | 142.0 | 82.0 | 0.364 | 0.0 |
DA DG HOH |
3.233 3.730 3.419 |
CD NH1 CB |
OP2 OP2 O |
||
| 4eyh | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2013-01-09 | ARG | A:360 | B:360 | 96.0 | 0.427 | E | -139.2 | 159.0 | 96.0 | 0.427 | 0.0 |
DA DG DG HOH |
3.099 3.524 9.876 3.892 |
CG NH1 NH1 N |
OP1 OP1 OP2 O |
||
| 4eyi | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2013-01-09 | ARG | A:360 | B:360 | 98.0 | 0.436 | E | -132.6 | 145.7 | 98.0 | 0.436 | 0.0 |
DA DG DG HOH |
3.252 3.654 9.846 4.127 |
CG NH1 NH1 N |
OP1 OP1 OP2 O |
||
| 4fs1 | 2 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-08-29 | ARG | C:360 | A:360 | 77.0 | 0.342 | E | -145.8 | 128.7 | 77.0 | 0.342 | 0.0 |
DA DG |
3.192 3.877 |
CD NH1 |
OP1 OP1 |
||
| 4fs2 | 2 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2012-08-29 | ARG | C:360 | A:360 | 90.0 | 0.4 | E | -139.6 | 137.0 | 90.0 | 0.4 | 0.0 |
DA DG HOH |
3.116 4.030 3.367 |
CD NH1 CB |
OP1 OP2 O |
||
| 5kt2 | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2016-08-31 | ARG | C:360 | A:385 | 95.0 | 0.422 | E | -135.4 | 134.4 | 95.0 | 0.422 | 0.0 |
DA DG HOH |
2.791 4.094 5.883 |
CD NH1 N |
OP1 OP2 O |
||
| 5kt3 | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2016-08-31 | ARG | C:360 | A:385 | 93.0 | 0.413 | E | -132.8 | 138.4 | 93.0 | 0.413 | 0.0 |
DA DG |
3.179 4.178 |
CA NH1 |
OP2 OP2 |
||
| 5ulw | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2017-04-19 | ARG | C:360 | A:360 | 94.0 | 0.418 | E | -143.3 | 127.6 | 94.0 | 0.418 | 0.0 |
DA DG |
3.893 3.833 |
NH1 NH1 |
O3' OP2 |
||
| 5ulx | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2017-04-19 | ARG | C:360 | A:360 | 91.0 | 0.404 | E | -132.3 | 129.1 | 91.0 | 0.404 | 0.0 |
DA DG HOH |
3.845 3.798 2.872 |
NH1 NH1 NH1 |
O3' OP2 O |
||
| 2alz | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2005-10-25 | ARG | C:336 | A:360 | 115.0 | 0.511 | E | -136.2 | 109.7 | 115.0 | 0.511 | 0.0 |
DA DG DC DT HOH |
3.934 4.758 8.998 4.747 9.241 |
CD NH2 C CA N |
O5' OP1 O3' O3' O |
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| 3h4b | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-07-21 | ARG | A:336 | A:360 | 95.0 | 0.422 | -113.2 | 103.0 | 95.0 | 0.422 | 0.0 |
DA DG HOH |
3.905 4.881 3.475 |
NH1 NH1 C |
O5' OP2 O |
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| 3h4d | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-07-21 | ARG | A:336 | A:360 | 102.0 | 0.453 | E | -113.4 | 107.8 | 102.0 | 0.453 | 0.0 |
DA DG HOH |
3.513 4.901 5.903 |
NH1 NH1 N |
O5' P O |
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| 3h40 | 1 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2009-07-21 | ARG | A:335 | A:360 | 102.0 | 0.453 | -108.7 | 107.3 | 102.0 | 0.453 | 0.0 |
DA DG HOH |
3.451 4.815 5.877 |
NH1 NH1 N |
O5' P O |
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| 1t3n | 3 | Q9UNA4 | 100.0 | 0.0 |
X-RAY |
2004-07-20 | ARG | C:334 | A:360 | 99.0 | 0.44 | E | -140.1 | 143.7 | 99.0 | 0.44 | 0.0 |
DC DT DT DC DC HOH |
9.256 5.620 3.144 2.520 9.774 3.555 |
C NE NH2 NH2 NH2 NH2 |
O3' O3' O3' OP1 OP2 O |
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| ARG | D:334 | B:780 | 78.0 | 0.347 | -133.1 | 123.2 | 78.0 | 0.347 | 0.0 |
DG DA DA DG HOH |
8.811 5.706 3.495 5.247 3.358 |
C CA C N N |
O3' O3' OP2 OP1 O |
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| 1zet | 3 | 21619716 | 100.0 | 0.0 |
X-RAY |
2005-07-19 | ARG | C:334 | A:360 | 64.0 | 0.284 | -174.4 | 108.5 | 64.0 | 0.284 | 0.0 |
DA DA DG DG HOH |
5.467 2.966 2.639 8.162 8.450 |
C NE CZ N CD |
C3' C3' OP2 N7 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q9una4-f1 | 1 | Q9UNA4 | 100.0 | 0.0 | ARG | A:385 | A:385 | 108.0 | 0.48 | E | -137.4 | 146.6 | |