Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr18 51818217 . A C CCDS11954.2:NM_007195.2:c.1213Atg>Ctg_NP_009126.2:p.405M>L Homo sapiens DNA polymerase iota (POLI), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5kt6 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:405 A:405 37.0 0.2 H -72.7 -55.7 37.0 0.2 0.0
5kt7 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:405 A:380 43.0 0.232 H -47.4 -71.6 43.0 0.232 0.0
5kt4 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 MET C:405 A:405 37.0 0.2 H -67.7 -61.5 37.0 0.2 0.0
5kt5 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 MET C:405 A:405 39.0 0.211 H -47.5 -66.1 39.0 0.211 0.0
2dpi 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 MET C:380 A:380 48.0 0.259 H -62.2 -49.6 48.0 0.259 0.0
2dpj 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 MET C:380 A:380 50.0 0.27 H -58.5 -53.8 50.0 0.27 0.0 HOH
 8.991
 N
 O
2fll 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-12 MET C:380 A:380 52.0 0.281 H -70.4 -64.6 52.0 0.281 0.0
2fln 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 MET C:380 A:380 54.0 0.292 H -57.2 -56.4 54.0 0.292 0.0
2flp 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 MET C:380 A:380 53.0 0.286 -59.5 -64.3 53.0 0.286 0.0 HOH
 9.876
 O
 O
3epg 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 MET A:380 A:380 61.0 0.33 H -66.8 -45.0 61.0 0.33 0.0 HOH
 8.520
 CE
 O
3epi 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 MET A:380 A:380 55.0 0.297 H -72.1 -49.9 55.0 0.297 0.0 HOH
 7.926
 N
 O
3g6v 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 MET A:380 A:380 66.0 0.357 -83.3 -35.6 66.0 0.357 0.0
3g6x 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 MET A:380 A:380 62.0 0.335 H -56.1 -72.9 62.0 0.335 0.0
3g6y 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 MET A:380 A:380 56.0 0.303 H -64.5 -57.2 56.0 0.303 0.0
3gv5 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 MSE A:380 B:380 57.0 0.308 H -53.5 -52.4 57.0 0.308 0.0 HOH
 3.531
 CE
 O
MSE D:380 D:380 53.0 0.286 H -60.4 -56.0 NA NA NA
3gv7 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 MET A:380 B:380 52.0 0.281 H -53.1 -44.6 52.0 0.281 0.0 HOH
 6.083
 N
 O
3gv8 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 MET A:380 B:380 50.0 0.27 H -56.9 -49.6 50.0 0.27 0.0 HOH
 8.885
 O
 O
3ngd 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 MET C:380 A:380 42.0 0.227 S -110.4 -46.7 42.0 0.227 0.0 HOH
 3.650
 O
 O
3osn 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 MET C:380 A:380 44.0 0.238 H -62.5 -62.3 44.0 0.238 0.0 HOH
 7.994
 CG
 O
3q8p 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:380 B:380 48.0 0.259 H -49.7 -66.8 48.0 0.259 0.0 HOH
 3.070
 N
 O
3q8q 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:380 B:380 49.0 0.265 H -48.6 -66.9 49.0 0.265 0.0 HOH
 2.994
 CG
 O
3q8r 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:380 B:380 51.0 0.276 H -53.6 -67.9 51.0 0.276 0.0 HOH
 3.245
 N
 O
3q8s 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:380 B:380 53.0 0.286 H -54.3 -66.4 53.0 0.286 0.0 HOH
 3.685
 CB
 O
4ebc 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 MET A:380 A:380 43.0 0.232 H -63.8 -39.5 43.0 0.232 0.0
4ebd 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 MET A:380 A:380 40.0 0.216 H -57.3 -51.0 40.0 0.216 0.0
4ebe 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 MET A:380 A:380 54.0 0.292 H -65.8 -36.0 54.0 0.292 0.0 HOH
 4.718
 N
 O
4eyh 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 MET A:380 B:380 49.0 0.265 H -56.0 -67.4 49.0 0.265 0.0
4eyi 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 MET A:380 B:380 43.0 0.232 H -75.1 -74.7 43.0 0.232 0.0
4fs1 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 MET C:380 A:380 49.0 0.265 H -53.1 -65.2 49.0 0.265 0.0 HOH
 9.394
 N
 O
4fs2 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 MET C:380 A:380 50.0 0.27 H -49.2 -54.8 50.0 0.27 0.0
5kt2 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:380 A:405 40.0 0.216 H -65.0 -55.4 40.0 0.216 0.0
5kt3 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:380 A:405 42.0 0.227 H -60.3 -67.9 42.0 0.227 0.0
5ulw 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 MET C:380 A:380 65.0 0.351 H -60.7 -70.0 65.0 0.351 0.0
5ulx 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 MET C:380 A:380 66.0 0.357 H -60.3 -63.0 66.0 0.357 0.0 HOH
 2.465
 SD
 O
2alz 3 Q9UNA4 100.0 0.0 X-RAY
 2005-10-25 MET C:356 A:380 54.0 0.292 H -74.8 -44.9 54.0 0.292 0.0
3h4b 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 MET A:356 A:380 51.0 0.276 H -64.2 -61.4 51.0 0.276 0.0 HOH
 5.027
 O
 O
3h4d 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 MET A:356 A:380 51.0 0.276 H -62.5 -61.5 51.0 0.276 0.0 HOH
 7.562
 CG
 O
3h40 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 MET A:355 A:380 60.0 0.324 H -55.5 -67.6 60.0 0.324 0.0 HOH
 7.515
 CG
 O
1t3n 3 Q9UNA4 100.0 0.0 X-RAY
 2004-07-20 MET C:354 A:380 19.0 NA H -25.1 -43.9 19.0 NA NA HOH
 5.098
 N
 O
MET D:354 B:800 23.0 NA H -70.7 -35.9 23.0 NA NA HOH
 5.071
 N
 O
1zet 3 21619716 100.0 0.0 X-RAY
 2005-07-19 MET C:354 A:380 31.0 0.168 H -51.0 -61.2 31.0 0.168 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9una4-f1 1 Q9UNA4 100.0 0.0 MET A:405 A:405 41.0 0.222 H -61.3 -57.7