Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr18 51818221 . C A CCDS11954.2:NM_007195.2:c.1217aCc>aAc_NP_009126.2:p.406T>N Homo sapiens DNA polymerase iota (POLI), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5kt6 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 THR C:406 A:406 98.0 0.7 H -53.8 -45.8 98.0 0.7 0.0
5kt7 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 THR C:406 A:381 87.0 0.621 H -47.1 -48.8 87.0 0.621 0.0
5kt4 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 THR C:406 A:406 93.0 0.664 H -48.7 -52.8 93.0 0.664 0.0
5kt5 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 THR C:406 A:406 90.0 0.643 H -46.4 -55.7 90.0 0.643 0.0
2dpi 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 THR C:381 A:381 124.0 0.886 H -58.1 -27.4 124.0 0.886 0.0
2dpj 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 THR C:381 A:381 115.0 0.821 H -60.2 -48.7 115.0 0.821 0.0
2fll 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-12 THR C:381 A:381 116.0 0.829 H -33.5 -53.4 116.0 0.829 0.0
2fln 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 THR C:381 A:381 111.0 0.793 H -46.3 -45.9 111.0 0.793 0.0
2flp 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 THR C:381 A:381 111.0 0.793 H -15.0 -87.2 111.0 0.793 0.0 HOH
 8.536
 C
 O
3epg 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 THR A:381 A:381 105.0 0.75 H -44.9 -65.5 105.0 0.75 0.0 HOH
 8.375
 C
 O
3epi 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 THR A:381 A:381 102.0 0.729 H -55.0 -46.6 102.0 0.729 0.0 HOH
 7.598
 O
 O
3g6v 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 THR A:381 A:381 97.0 0.693 H -63.4 -34.8 97.0 0.693 0.0
3g6x 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 THR A:381 A:381 114.0 0.814 H -51.0 -40.6 114.0 0.814 0.0
3g6y 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 THR A:381 A:381 120.0 0.857 H -59.7 -45.2 120.0 0.857 0.0
3gv5 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 THR A:381 B:381 69.0 0.493 H -62.1 -50.9 69.0 0.493 0.0 HOH
 3.246
 CG2
 O
THR D:381 D:381 79.0 0.564 H -66.3 -41.1 NA NA NA
3gv7 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 THR A:381 B:381 86.0 0.614 H -72.7 -41.9 86.0 0.614 0.0 HOH
 4.686
 OG1
 O
3gv8 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 THR A:381 B:381 88.0 0.629 H -68.7 -42.5 88.0 0.629 0.0 HOH
 6.216
 O
 O
3ngd 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 THR C:381 A:381 113.0 0.807 T -43.6 -43.7 113.0 0.807 0.0 HOH
 2.307
 O
 O
3osn 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 THR C:381 A:381 88.0 0.629 H -50.3 -53.1 88.0 0.629 0.0 HOH
 6.748
 O
 O
3q8p 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 THR A:381 B:381 65.0 0.464 H -52.9 -45.7 65.0 0.464 0.0 HOH
 3.608
 CA
 O
3q8q 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 THR A:381 B:381 64.0 0.457 H -51.0 -48.1 64.0 0.457 0.0 HOH
 4.060
 O
 O
3q8r 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 THR A:381 B:381 61.0 0.436 H -44.6 -57.7 61.0 0.436 0.0 HOH
 2.811
 CB
 O
3q8s 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 THR A:381 B:381 69.0 0.493 H -53.5 -40.2 69.0 0.493 0.0 HOH
 2.904
 CG2
 O
4ebc 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 THR A:381 A:381 92.0 0.657 H -62.7 -46.6 92.0 0.657 0.0
4ebd 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 THR A:381 A:381 84.0 0.6 H -45.1 -55.8 84.0 0.6 0.0
4ebe 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 THR A:381 A:381 98.0 0.7 H -64.3 -51.0 98.0 0.7 0.0 HOH
 5.101
 N
 O
4eyh 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 THR A:381 B:381 93.0 0.664 H -53.7 -43.6 93.0 0.664 0.0
4eyi 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 THR A:381 B:381 97.0 0.693 H -37.9 -43.6 97.0 0.693 0.0
4fs1 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 THR C:381 A:381 96.0 0.686 H -48.8 -50.5 96.0 0.686 0.0
4fs2 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 THR C:381 A:381 88.0 0.629 H -61.4 -49.4 88.0 0.629 0.0
5kt2 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 THR C:381 A:406 85.0 0.607 H -56.8 -50.0 85.0 0.607 0.0
5kt3 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 THR C:381 A:406 87.0 0.621 H -46.2 -50.8 87.0 0.621 0.0
5ulw 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 THR C:381 A:381 84.0 0.6 H -41.1 -44.5 84.0 0.6 0.0
5ulx 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 THR C:381 A:381 91.0 0.65 H -51.1 -44.1 91.0 0.65 0.0 HOH
 5.139
 N
 O
2alz 3 Q9UNA4 100.0 0.0 X-RAY
 2005-10-25 THR C:357 A:381 116.0 0.829 H -43.0 -64.4 116.0 0.829 0.0
3h4b 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 THR A:357 A:381 111.0 0.793 H -21.8 -71.3 111.0 0.793 0.0 HOH
 2.157
 O
 O
3h4d 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 THR A:357 A:381 112.0 0.8 H -22.3 -60.8 112.0 0.8 0.0
3h40 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 THR A:356 A:381 113.0 0.807 H -12.9 -63.0 113.0 0.807 0.0
1t3n 3 Q9UNA4 100.0 0.0 X-RAY
 2004-07-20 THR C:355 A:381 58.0 NA H -69.9 -36.4 58.0 NA NA HOH
 6.800
 N
 O
THR D:355 B:801 60.0 NA H -59.5 -52.3 60.0 NA NA HOH
 6.390
 N
 O
1zet 3 21619716 100.0 0.0 X-RAY
 2005-07-19 THR C:355 A:381 98.0 0.7 H -53.7 -55.9 98.0 0.7 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9una4-f1 1 Q9UNA4 100.0 0.0 THR A:406 A:406 95.0 0.679 H -58.4 -48.9