Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr18 51818226 . A C CCDS11954.2:NM_007195.2:c.1222Atg>Ctg_NP_009126.2:p.408M>L Homo sapiens DNA polymerase iota (POLI), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5kt6 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:408 A:408 5.0 0.027 H -49.6 -47.4 5.0 0.027 0.0
5kt7 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:408 A:383 1.0 0.005 H -60.2 -41.8 1.0 0.005 0.0
5kt4 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 MET C:408 A:408 6.0 0.032 H -59.0 -42.4 6.0 0.032 0.0
5kt5 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 MET C:408 A:408 4.0 0.022 H -59.2 -41.7 4.0 0.022 0.0
2dpi 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 MET C:383 A:383 14.0 0.076 H -60.2 -45.1 14.0 0.076 0.0
2dpj 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 MET C:383 A:383 17.0 0.092 H -38.5 -56.1 17.0 0.092 0.0 HOH
 8.675
 CE
 O
2fll 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-12 MET C:383 A:383 13.0 0.07 H -45.7 -52.9 13.0 0.07 0.0
2fln 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 MET C:383 A:383 13.0 0.07 H -43.5 -60.8 13.0 0.07 0.0
2flp 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 MET C:383 A:383 11.0 0.059 H -50.2 -66.8 11.0 0.059 0.0 HOH
 7.052
 CE
 O
3epg 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 MET A:383 A:383 7.0 0.038 H -67.1 -42.4 7.0 0.038 0.0 HOH
 7.996
 N
 O
3epi 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 MET A:383 A:383 3.0 0.016 H -59.8 -36.8 3.0 0.016 0.0 HOH
 7.686
 N
 O
3g6v 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 MET A:383 A:383 13.0 0.07 H -62.0 -44.1 13.0 0.07 0.0
3g6x 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 MET A:383 A:383 12.0 0.065 H -66.9 -43.5 12.0 0.065 0.0
3g6y 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 MET A:383 A:383 12.0 0.065 H -71.4 -46.5 12.0 0.065 0.0
3gv5 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 MSE A:383 B:383 1.0 0.005 H -66.4 -43.1 1.0 0.005 0.0 HOH
 6.444
 C
 O
MSE D:383 D:383 0.0 0.0 H -64.4 -48.0 NA NA NA
3gv7 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 MET A:383 B:383 0.0 0.0 H -76.0 -42.0 0.0 0.0 0.0 HOH
 6.794
 N
 O
3gv8 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 MET A:383 B:383 2.0 0.011 H -74.2 -42.8 2.0 0.011 0.0 HOH
 6.491
 N
 O
3ngd 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 MET C:383 A:383 10.0 0.054 H -69.2 -34.1 10.0 0.054 0.0 HOH
 3.273
 N
 O
3osn 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 MET C:383 A:383 1.0 0.005 H -70.4 -41.2 1.0 0.005 0.0 HOH
 8.423
 O
 O
3q8p 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:383 B:383 1.0 0.005 H -74.5 -42.9 1.0 0.005 0.0 HOH
 6.126
 N
 O
3q8q 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:383 B:383 1.0 0.005 H -71.7 -40.2 1.0 0.005 0.0 HOH
 7.101
 C
 O
3q8r 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:383 B:383 8.0 0.043 H -56.0 -52.8 8.0 0.043 0.0 HOH
 6.726
 CG
 O
3q8s 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:383 B:383 2.0 0.011 H -68.0 -39.9 2.0 0.011 0.0 HOH
 5.260
 N
 O
4ebc 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 MET A:383 A:383 5.0 0.027 H -55.6 -46.2 5.0 0.027 0.0
4ebd 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 MET A:383 A:383 3.0 0.016 H -55.7 -44.4 3.0 0.016 0.0
4ebe 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 MET A:383 A:383 3.0 0.016 H -63.3 -42.6 3.0 0.016 0.0 HOH
 6.096
 N
 O
4eyh 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 MET A:383 B:383 4.0 0.022 H -63.8 -58.6 4.0 0.022 0.0
4eyi 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 MET A:383 B:383 9.0 0.049 H -53.3 -61.3 9.0 0.049 0.0
4fs1 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 MET C:383 A:383 10.0 0.054 H -52.6 -47.9 10.0 0.054 0.0
4fs2 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 MET C:383 A:383 1.0 0.005 H -66.2 -41.4 1.0 0.005 0.0 HOH
 8.951
 SD
 O
5kt2 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:383 A:408 3.0 0.016 H -58.3 -36.8 3.0 0.016 0.0
5kt3 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:383 A:408 4.0 0.022 H -57.1 -38.6 4.0 0.022 0.0
5ulw 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 MET C:383 A:383 9.0 0.049 H -58.7 -33.4 9.0 0.049 0.0
5ulx 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 MET C:383 A:383 2.0 0.011 H -59.4 -46.8 2.0 0.011 0.0 HOH
 5.886
 CB
 O
2alz 3 Q9UNA4 100.0 0.0 X-RAY
 2005-10-25 MET C:359 A:383 14.0 0.076 H -35.0 -49.6 14.0 0.076 0.0
3h4b 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 MET A:359 A:383 15.0 0.081 H -40.0 -49.6 15.0 0.081 0.0 HOH
 4.992
 N
 O
3h4d 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 MET A:359 A:383 14.0 0.076 H -48.3 -42.1 14.0 0.076 0.0
3h40 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 MET A:358 A:383 21.0 0.114 H -49.8 -35.3 21.0 0.114 0.0
1t3n 3 Q9UNA4 100.0 0.0 X-RAY
 2004-07-20 MET C:357 A:383 17.0 0.092 H -58.2 -37.0 17.0 0.092 0.0 HOH
 8.039
 CE
 O
MET D:357 B:803 16.0 0.086 H -82.9 -32.6 16.0 0.086 0.0 HOH
 7.552
 N
 O
1zet 3 21619716 100.0 0.0 X-RAY
 2005-07-19 MET C:357 A:383 5.0 0.027 H -60.0 -33.1 5.0 0.027 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9una4-f1 1 Q9UNA4 100.0 0.0 MET A:408 A:408 0.0 0.0 H -71.4 -39.9