Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr18 51818242 . T A CCDS11954.2:NM_007195.2:c.1238aTg>aAg_NP_009126.2:p.413M>K Homo sapiens DNA polymerase iota (POLI), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5kt6 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:413 A:413 6.0 0.032 H -60.1 -41.3 6.0 0.032 0.0
5kt7 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:413 A:388 13.0 0.07 H -71.6 -39.7 13.0 0.07 0.0
5kt4 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 MET C:413 A:413 13.0 0.07 H -73.6 -34.2 13.0 0.07 0.0
5kt5 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 MET C:413 A:413 15.0 0.081 H -69.3 -38.9 15.0 0.081 0.0
2dpi 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 MET C:388 A:388 2.0 0.011 H -55.9 -48.0 2.0 0.011 0.0
2dpj 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 MET C:388 A:388 0.0 0.0 H -56.7 -46.5 0.0 0.0 0.0
2fll 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-12 MET C:388 A:388 4.0 0.022 H -66.3 -40.5 4.0 0.022 0.0
2fln 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 MET C:388 A:388 10.0 0.054 H -47.7 -53.2 10.0 0.054 0.0
2flp 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 MET C:388 A:388 9.0 0.049 H -89.3 -36.1 9.0 0.049 0.0
3epg 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 MET A:388 A:388 4.0 0.022 H -76.4 -29.2 4.0 0.022 0.0 HOH
 4.341
 CE
 O
3epi 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 MET A:388 A:388 4.0 0.022 H -81.0 -34.8 4.0 0.022 0.0 HOH
 3.721
 CE
 O
3g6v 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 MET A:388 A:388 4.0 0.022 H -56.1 -38.4 4.0 0.022 0.0
3g6x 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 MET A:388 A:388 8.0 0.043 H -57.8 -15.7 8.0 0.043 0.0
3g6y 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 MET A:388 A:388 4.0 0.022 H -49.2 -39.1 4.0 0.022 0.0
3gv5 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 MSE A:388 B:388 5.0 0.027 H -67.8 -34.3 5.0 0.027 0.0 HOH
 2.741
 CE
 O
MSE D:388 D:388 4.0 0.022 H -68.6 -30.4 NA NA NA
3gv7 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 MET A:388 B:388 6.0 0.032 H -71.2 -42.4 6.0 0.032 0.0 HOH
 7.392
 O
 O
3gv8 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 MET A:388 B:388 7.0 0.038 H -68.0 -34.2 7.0 0.038 0.0 HOH
 4.128
 CB
 O
3ngd 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 MET C:388 A:388 5.0 0.027 H -74.9 -35.0 5.0 0.027 0.0 HOH
 6.839
 CG
 O
3osn 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 MET C:388 A:388 8.0 0.043 H -67.8 -30.2 8.0 0.043 0.0 HOH
 3.661
 CG
 O
3q8p 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:388 B:388 6.0 0.032 H -69.6 -35.9 6.0 0.032 0.0 HOH
 3.548
 CG
 O
3q8q 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:388 B:388 7.0 0.038 H -73.0 -40.8 7.0 0.038 0.0 HOH
 3.621
 CG
 O
3q8r 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:388 B:388 6.0 0.032 H -62.0 -47.6 6.0 0.032 0.0 HOH
 4.851
 CE
 O
3q8s 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:388 B:388 6.0 0.032 H -71.7 -34.0 6.0 0.032 0.0 HOH
 3.848
 CG
 O
4ebc 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 MET A:388 A:388 5.0 0.027 H -72.5 -37.4 5.0 0.027 0.0
4ebd 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 MET A:388 A:388 3.0 0.016 H -69.3 -35.2 3.0 0.016 0.0
4ebe 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 MET A:388 A:388 2.0 0.011 H -66.2 -37.9 2.0 0.011 0.0 HOH
 5.851
 N
 O
4eyh 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 MET A:388 B:388 16.0 0.086 H -54.4 -43.5 16.0 0.086 0.0
4eyi 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 MET A:388 B:388 22.0 0.119 H -70.5 -45.1 22.0 0.119 0.0
4fs1 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 MET C:388 A:388 9.0 0.049 H -53.8 -50.0 9.0 0.049 0.0
4fs2 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 MET C:388 A:388 4.0 0.022 H -59.3 -40.5 4.0 0.022 0.0
5kt2 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:388 A:413 8.0 0.043 H -75.6 -37.5 8.0 0.043 0.0
5kt3 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:388 A:413 6.0 0.032 H -66.5 -42.3 6.0 0.032 0.0
5ulw 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 MET C:388 A:388 16.0 0.086 H -64.2 -45.8 16.0 0.086 0.0
5ulx 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 MET C:388 A:388 16.0 0.086 H -59.5 -43.0 16.0 0.086 0.0 HOH
 6.565
 SD
 O
2alz 3 Q9UNA4 100.0 0.0 X-RAY
 2005-10-25 MET C:364 A:388 8.0 0.043 H -63.2 -44.2 8.0 0.043 0.0
3h4b 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 MET A:364 A:388 9.0 0.049 H -59.9 -47.5 9.0 0.049 0.0 HOH
 6.429
 CG
 O
3h4d 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 MET A:364 A:388 23.0 0.124 H -63.2 -44.7 23.0 0.124 0.0 HOH
 4.955
 CE
 O
3h40 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 MET A:363 A:388 23.0 0.124 H -61.6 -37.2 23.0 0.124 0.0 HOH
 3.638
 CE
 O
1t3n 3 Q9UNA4 100.0 0.0 X-RAY
 2004-07-20 MET C:362 A:388 71.0 0.384 H -62.8 -39.0 71.0 0.384 0.0 HOH
 4.775
 O
 O
MET D:362 B:808 41.0 0.222 I -132.1 -40.1 41.0 0.222 0.0
1zet 3 21619716 100.0 0.0 X-RAY
 2005-07-19 MET C:362 A:388 55.0 0.297 H -85.4 47.3 55.0 0.297 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9una4-f1 1 Q9UNA4 100.0 0.0 MET A:413 A:413 8.0 0.043 H -69.7 -28.5