Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr18 51818259 . A C CCDS11954.2:NM_007195.2:c.1255Atg>Ctg_NP_009126.2:p.419M>L Homo sapiens DNA polymerase iota (POLI), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5kt6 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:419 A:419 31.0 0.168 H -78.2 -44.2 31.0 0.168 0.0 DA
DG
 6.941
6.117
 CG
SD
 OP1
OP2
5kt7 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:419 A:394 10.0 0.054 H -71.8 -44.6 10.0 0.054 0.0 DA
DG
 6.875
5.433
 CE
CE
 O3'
OP2
5kt4 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 MET C:419 A:419 24.0 0.13 H -74.1 -52.6 24.0 0.13 0.0 DA
DG
 6.691
5.458
 CE
CE
 O3'
OP2
5kt5 3 Q9UNA4 99.78 0.0 X-RAY
 2016-08-31 MET C:419 A:419 12.0 0.065 H -89.2 -36.8 12.0 0.065 0.0 DA
DG
 7.187
5.831
 SD
SD
 C3'
OP2
2dpi 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 MET C:394 A:394 41.0 0.222 -114.9 360.0 41.0 0.222 0.0 DA
DG
DT
 7.511
6.108
8.845
 SD
SD
SD
 C3'
OP2
O3'
2dpj 3 Q9UNA4 100.0 0.0 X-RAY
 2006-07-04 MET C:394 A:394 45.0 0.243 -97.8 360.0 45.0 0.243 0.0 DA
DG
DT
HOH
 7.693
6.275
9.462
2.410
 SD
SD
SD
C
 O5'
OP2
O3'
O
2fll 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-12 MET C:394 A:394 45.0 0.243 -112.3 360.0 45.0 0.243 0.0 DA
DG
DT
 7.396
6.009
9.015
 SD
CE
SD
 O3'
OP2
O3'
2fln 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 MET C:394 A:394 54.0 0.292 -139.8 360.0 54.0 0.292 0.0 DA
DG
DT
 7.231
5.770
8.978
 SD
SD
SD
 O3'
OP2
O3'
2flp 3 Q9UNA4 100.0 0.0 X-RAY
 2006-12-05 MET C:394 A:394 53.0 0.286 -95.8 360.0 53.0 0.286 0.0 DA
DG
DT
 7.747
6.466
8.712
 SD
SD
SD
 C3'
OP2
O3'
3epg 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 MET A:394 A:394 17.0 0.092 T -133.0 -5.5 17.0 0.092 0.0 DA
DG
DT
 7.428
5.801
9.941
 SD
SD
SD
 OP2
OP2
O3'
3epi 1 Q9UNA4 100.0 0.0 X-RAY
 2008-12-16 MET A:394 A:394 17.0 0.092 H -62.3 -95.8 17.0 0.092 0.0 DA
DG
DT
HOH
 7.597
6.775
9.184
7.823
 SD
SD
CE
C
 O3'
OP1
O3'
O
3g6v 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 MET A:394 A:394 35.0 0.189 -85.1 360.0 35.0 0.189 0.0 DA
DG
 7.402
6.244
 SD
SD
 C3'
OP2
3g6x 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 MET A:394 A:394 40.0 0.216 -101.7 360.0 40.0 0.216 0.0 DA
DG
HOH
 7.160
5.950
9.652
 SD
SD
SD
 C3'
OP2
O
3g6y 1 Q9UNA4 100.0 0.0 X-RAY
 2009-05-12 MET A:394 A:394 41.0 0.222 -100.1 360.0 41.0 0.222 0.0 DA
DG
 7.511
6.216
 SD
SD
 C3'
OP2
3gv5 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 MSE A:394 B:394 12.0 0.065 H -84.0 -39.9 12.0 0.065 0.0 DT
DG
DG
HOH
 9.588
7.172
5.793
3.719
 CG
SE
SE
O
 O3'
C3'
OP2
O
MSE D:394 D:394 14.0 0.076 H -76.7 -34.9 NA NA NA
3gv7 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 MET A:394 B:394 12.0 0.065 H -86.8 -34.4 12.0 0.065 0.0 DA
DG
HOH
 6.678
5.080
2.306
 CE
CE
SD
 O3'
OP2
O
3gv8 1 Q9UNA4 100.0 0.0 X-RAY
 2009-06-02 MET A:394 B:394 13.0 0.07 H -100.3 -34.3 13.0 0.07 0.0 DA
DG
HOH
 7.277
5.845
7.564
 SD
SD
SD
 C3'
OP2
O
3ngd 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 MET C:394 A:394 46.0 0.249 -135.5 360.0 46.0 0.249 0.0 DA
DG
HOH
 7.562
6.098
9.660
 SD
SD
O
 O3'
OP2
O
3osn 2 Q9UNA4 100.0 0.0 X-RAY
 2010-10-20 MET C:394 A:394 13.0 0.07 H -102.3 -36.0 13.0 0.07 0.0 DA
DG
HOH
 7.381
5.842
7.357
 SD
SD
SD
 C3'
OP2
O
3q8p 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:394 B:394 17.0 0.092 H -80.1 -51.5 17.0 0.092 0.0 DA
DG
HOH
 7.255
5.718
2.683
 CG
SD
O
 O3'
OP2
O
3q8q 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:394 B:394 13.0 0.07 H -104.6 -25.4 13.0 0.07 0.0 DA
DG
HOH
 7.003
5.583
2.723
 SD
SD
O
 O3'
OP2
O
3q8r 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:394 B:394 30.0 0.162 H -98.9 -32.1 30.0 0.162 0.0 DA
DG
HOH
 7.083
5.166
3.083
 CE
CE
O
 O3'
OP2
O
3q8s 1 Q9UNA4 100.0 0.0 X-RAY
 2011-02-23 MET A:394 B:394 13.0 0.07 H -118.2 -3.7 13.0 0.07 0.0 DA
DG
HOH
 7.192
5.517
7.319
 CE
CE
O
 O3'
OP2
O
4ebc 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 MET A:394 A:394 17.0 0.092 H -96.7 -44.9 17.0 0.092 0.0 DA
DG
 7.585
5.849
 CE
SD
 OP1
OP2
4ebd 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 MET A:394 A:394 14.0 0.076 H -114.7 -11.4 14.0 0.076 0.0 DA
DG
HOH
 7.223
5.556
7.304
 CE
CE
SD
 C3'
OP2
O
4ebe 1 Q9UNA4 100.0 0.0 X-RAY
 2012-06-13 MET A:394 A:394 17.0 0.092 H -95.0 -45.2 17.0 0.092 0.0 DA
DG
HOH
 6.999
5.385
2.753
 SD
SD
N
 C3'
OP2
O
4eyh 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 MET A:394 B:394 17.0 0.092 S -86.5 -33.0 17.0 0.092 0.0 DA
DG
HOH
 6.949
5.991
7.766
 SD
SD
SD
 OP1
OP1
O
4eyi 1 Q9UNA4 100.0 0.0 X-RAY
 2013-01-09 MET A:394 B:394 17.0 0.092 H -91.6 -43.6 17.0 0.092 0.0 DA
DG
HOH
 7.153
6.219
7.897
 SD
SD
SD
 OP1
OP2
O
4fs1 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 MET C:394 A:394 12.0 0.065 H -91.1 -43.2 12.0 0.065 0.0 DA
DG
 7.324
5.915
 CG
SD
 OP1
OP2
4fs2 2 Q9UNA4 100.0 0.0 X-RAY
 2012-08-29 MET C:394 A:394 13.0 0.07 H -81.4 -47.5 13.0 0.07 0.0 DA
DG
HOH
 7.055
5.593
7.455
 SD
SD
SD
 O3'
OP2
O
5kt2 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:394 A:419 12.0 0.065 H -88.2 -35.7 12.0 0.065 0.0 DA
DG
HOH
 6.708
5.212
6.674
 CG
CE
CE
 OP1
OP2
O
5kt3 3 Q9UNA4 100.0 0.0 X-RAY
 2016-08-31 MET C:394 A:419 11.0 0.059 H -91.9 -38.4 11.0 0.059 0.0 DA
DG
HOH
 6.923
5.355
9.841
 CE
CE
O
 O3'
OP2
O
5ulw 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 MET C:394 A:394 21.0 0.114 H -97.6 -28.9 21.0 0.114 0.0 DA
DG
 7.223
5.572
 SD
SD
 C3'
OP2
5ulx 3 Q9UNA4 100.0 0.0 X-RAY
 2017-04-19 MET C:394 A:394 15.0 0.081 H -94.9 -35.6 15.0 0.081 0.0 DA
DG
HOH
 7.018
5.560
4.390
 SD
SD
CG
 C3'
OP2
O
2alz 3 Q9UNA4 100.0 0.0 X-RAY
 2005-10-25 MET C:370 A:394 48.0 0.259 -62.9 360.0 48.0 0.259 0.0 DA
DG
DT
 7.761
6.355
9.086
 SD
CE
SD
 O5'
OP2
O3'
3h4b 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 MET A:370 A:394 39.0 0.211 -92.8 360.0 39.0 0.211 0.0 DA
DG
HOH
 8.122
6.961
7.933
 SD
SD
SD
 O5'
OP2
O
3h4d 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 MET A:370 A:394 38.0 0.205 -98.3 360.0 38.0 0.205 0.0 DA
DG
HOH
 8.112
7.036
7.906
 SD
SD
SD
 O5'
OP2
O
3h40 1 Q9UNA4 100.0 0.0 X-RAY
 2009-07-21 MET A:369 A:394 41.0 0.222 -101.4 360.0 41.0 0.222 0.0 DA
DG
HOH
 7.249
5.763
6.410
 CE
CE
CE
 O3'
OP2
O
1t3n 3 Q9UNA4 100.0 0.0 X-RAY
 2004-07-20 MET C:368 A:394 35.0 0.189 T -74.7 -15.1 35.0 0.189 0.0 DT
DT
DC
HOH
 9.938
7.018
4.805
6.999
 SD
SD
SD
SD
 O3'
O3'
OP1
O
MET D:368 B:814 92.0 NA S -49.1 155.4 92.0 NA NA DA
 9.996
 N
 OP1
1zet 3 21619716 100.0 0.0 X-RAY
 2005-07-19 MET C:368 A:394 8.0 0.043 S -91.2 81.5 8.0 0.043 0.0 DA
DG
DG
 5.073
2.831
7.408
 SD
SD
SD
 O3'
OP2
OP2

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9una4-f1 1 Q9UNA4 100.0 0.0 MET A:419 A:419 13.0 0.07 H -88.0 -38.4