Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 10610247 | . | C | A | CCDS12239.1:NM_012289.3:c.463Gtc>Ttc_NP_036421.2:p.155V>F | Homo sapiens kelch like ECH associated protein 1 (KEAP1), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6wcq | 3 | Q14145 | 99.84 | 0.0 |
EM |
2020-08-19 | VAL | C:162 | C:155 | 1.0 | 0.006 | H | -62.6 | -41.9 | 1.0 | 0.006 | 0.0 | ||||||
5nlb | 1 | Q14145 | 100.0 | 2e-106 |
X-RAY |
2017-04-19 | VAL | A:105 | A:155 | 6.0 | 0.039 | H | -61.4 | -49.7 | 6.0 | 0.039 | 0.0 | ||||||
7exi | 1 | Q14145 | 99.26 | 3e-92 |
X-RAY |
2021-12-01 | VAL | A:115 | A:155 | 0.0 | 0.0 | H | -61.8 | -41.9 | 0.0 | 0.0 | 0.0 |
HOH |
4.846 |
N |
O |
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5dad | 1 | Q14145 | 99.26 | 4e-91 |
X-RAY |
2016-08-10 | VAL | A:113 | A:155 | 6.0 | 0.039 | H | -66.9 | -40.3 | 6.0 | 0.039 | 0.0 |
TX6 |
4.119 |
CG2 |
C18 |
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5daf | 1 | Q14145 | 99.26 | 4e-91 |
X-RAY |
2016-08-10 | VAL | A:113 | A:155 | 4.0 | 0.026 | H | -64.4 | -48.9 | 4.0 | 0.026 | 0.0 |
58E HOH |
3.828 5.693 |
CG2 N |
C17 O |
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4cxi | 1 | Q14145 | 97.79 | 5e-90 |
X-RAY |
2014-06-18 | VAL | A:112 | A:155 | 1.0 | 0.006 | H | -72.8 | -47.6 | 1.0 | 0.006 | 0.0 |
HOH |
5.524 |
N |
O |
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4cxt | 1 | Q14145 | 97.79 | 5e-90 |
X-RAY |
2014-06-18 | VAL | A:112 | A:155 | 4.0 | 0.026 | H | -65.1 | -44.4 | 4.0 | 0.026 | 0.0 |
SXJ HOH |
3.649 5.971 |
CG2 N |
H68 O |
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5git | 1 | Q14145 | 97.79 | 5e-90 |
X-RAY |
2017-06-28 | VAL | A:112 | A:155 | 1.0 | 0.006 | H | -75.3 | -43.4 | 1.0 | 0.006 | 0.0 |
XXT HOH |
4.747 6.630 |
CG2 N |
O3 O |
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6w67 | 1 | Q14145 | 99.25 | 1e-89 |
X-RAY |
2020-08-19 | VAL | A:109 | A:155 | 0.0 | 0.0 | H | -72.4 | -38.5 | 0.0 | 0.0 | 0.0 |
HOH |
6.227 |
N |
O |
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6ffm | 1 | Q14145 | 99.25 | 1e-89 |
X-RAY |
2018-11-14 | VAL | A:111 | A:155 | 2.0 | 0.013 | H | -69.9 | -42.4 | 2.0 | 0.013 | 0.0 |
D8N |
6.245 |
HG23 |
N04 |
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6w68 | 1 | Q14145 | 98.5 | 4e-89 |
X-RAY |
2020-08-19 | VAL | A:109 | A:155 | 0.0 | 0.0 | H | -72.7 | -38.4 | 0.0 | 0.0 | 0.0 | ||||||
4cxj | 1 | Q14145 | 97.06 | 2e-88 |
X-RAY |
2014-06-18 | VAL | A:112 | A:155 | 3.0 | 0.019 | H | -64.5 | -51.5 | 3.0 | 0.019 | 0.0 |
HOH |
5.627 |
N |
O |
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6w66 | 3 | Q14145 | 98.5 | 2e-88 |
X-RAY |
2020-08-19 | VAL | C:109 | C:155 | 0.0 | 0.0 | H | -62.0 | -42.6 | 0.0 | 0.0 | 0.0 | ||||||
6w69 | 1 | Q14145 | 98.5 | 2e-88 |
X-RAY |
2020-08-19 | VAL | A:109 | A:155 | 0.0 | 0.0 | H | -65.3 | -38.8 | 0.0 | 0.0 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q14145-f1 | 1 | Q14145 | 100.0 | 0.0 | VAL | A:155 | A:155 | 6.0 | 0.039 | H | -64.0 | -44.5 |