Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 10610492 | . | C | A | CCDS12239.1:NM_012289.3:c.218aGc>aTc_NP_036421.2:p.73S>I | Homo sapiens kelch like ECH associated protein 1 (KEAP1), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6wcq | 3 | Q14145 | 99.84 | 0.0 |
EM |
2020-08-19 | SER | C:80 | C:73 | 75.0 | 0.652 | H | -85.3 | -14.9 | 62.0 | 0.539 | 0.113 |
B:Q9UF56:0.113 |
|||||
5nlb | 1 | Q14145 | 100.0 | 2e-106 |
X-RAY |
2017-04-19 | SER | A:23 | A:73 | 48.0 | 0.417 | T | -70.6 | 13.5 | 48.0 | 0.417 | 0.0 | ||||||
7exi | 1 | Q14145 | 99.26 | 3e-92 |
X-RAY |
2021-12-01 | SER | A:33 | A:73 | 62.0 | 0.539 | T | -88.4 | 5.5 | 62.0 | 0.539 | 0.0 |
HOH |
2.724 |
O |
O |
||
5dad | 1 | Q14145 | 99.26 | 4e-91 |
X-RAY |
2016-08-10 | SER | A:31 | A:73 | 71.0 | 0.617 | T | -78.4 | -7.1 | 71.0 | 0.617 | 0.0 | ||||||
5daf | 1 | Q14145 | 99.26 | 4e-91 |
X-RAY |
2016-08-10 | SER | A:31 | A:73 | 80.0 | 0.696 | T | -82.3 | -0.8 | 80.0 | 0.696 | 0.0 |
HOH |
8.031 |
O |
O |
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4cxi | 1 | Q14145 | 97.79 | 5e-90 |
X-RAY |
2014-06-18 | SER | A:30 | A:73 | 75.0 | 0.652 | H | -82.7 | -7.7 | 75.0 | 0.652 | 0.0 |
HOH |
2.937 |
OG |
O |
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4cxt | 1 | Q14145 | 97.79 | 5e-90 |
X-RAY |
2014-06-18 | SER | A:30 | A:73 | 70.0 | 0.609 | T | -77.6 | -9.3 | 70.0 | 0.609 | 0.0 |
HOH |
6.455 |
O |
O |
||
5git | 1 | Q14145 | 97.79 | 5e-90 |
X-RAY |
2017-06-28 | SER | A:30 | A:73 | 65.0 | 0.565 | T | -88.0 | 2.4 | 65.0 | 0.565 | 0.0 |
HOH |
2.937 |
OG |
O |
||
6w67 | 1 | Q14145 | 99.25 | 1e-89 |
X-RAY |
2020-08-19 | SER | A:27 | A:73 | 69.0 | 0.6 | T | -89.3 | 0.2 | 69.0 | 0.6 | 0.0 |
HOH |
4.861 |
N |
O |
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6ffm | 1 | Q14145 | 99.25 | 1e-89 |
X-RAY |
2018-11-14 | SER | A:29 | A:73 | 80.0 | 0.696 | T | -87.0 | -4.8 | 80.0 | 0.696 | 0.0 |
HOH |
3.385 |
O |
O |
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6w68 | 1 | Q14145 | 98.5 | 4e-89 |
X-RAY |
2020-08-19 | SER | A:27 | A:73 | 68.0 | 0.591 | T | -89.6 | -0.2 | 68.0 | 0.591 | 0.0 |
HOH |
6.315 |
O |
O |
||
4cxj | 1 | Q14145 | 97.06 | 2e-88 |
X-RAY |
2014-06-18 | SER | A:30 | A:73 | 72.0 | 0.626 | T | -86.0 | -2.4 | 72.0 | 0.626 | 0.0 |
HOH |
3.740 |
OG |
O |
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6w66 | 3 | Q14145 | 98.5 | 2e-88 |
X-RAY |
2020-08-19 | SER | C:27 | C:73 | 74.0 | 0.643 | T | -80.9 | -7.7 | 57.0 | 0.496 | 0.147 |
B:Q9UF56:0.148 |
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6w69 | 1 | Q14145 | 98.5 | 2e-88 |
X-RAY |
2020-08-19 | SER | A:27 | A:73 | 74.0 | 0.643 | T | -77.2 | -3.9 | 74.0 | 0.643 | 0.0 |
HOH |
3.021 |
OG |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q14145-f1 | 1 | Q14145 | 100.0 | 0.0 | SER | A:73 | A:73 | 63.0 | 0.548 | T | -86.1 | 4.8 |