Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr19 | 11491756 | . | G | A | CCDS12260.1:NM_000121.3:c.715Cct>Tct_NP_000112.1:p.239P>S | Homo sapiens erythropoietin receptor (EPOR), transcript variant 1, mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
2jix | 2 | P19235 | 100.0 | 5e-161 |
X-RAY |
2007-07-10 | PRO | B:215 | B:215 | 80.0 | 0.552 | -77.3 | 179.8 | NA | NA | NA | |||||||
PRO | C:215 | C:215 | 80.0 | 0.552 | -84.3 | -176.8 | 80.0 | 0.552 | 0.0 | ||||||||||||||
PRO | E:215 | E:215 | 76.0 | 0.524 | -76.0 | 174.6 | NA | NA | NA | ||||||||||||||
1cn4 | 1 | P19235 | 98.23 | 9e-159 |
X-RAY |
1999-08-11 | PRO | A:218 | A:215 | 99.0 | 0.683 | -62.7 | 162.6 | 99.0 | 0.683 | 0.0 |
HOH |
5.454 |
O |
O |
|||
PRO | B:218 | B:215 | 80.0 | 0.552 | -67.5 | 158.6 | 80.0 | 0.552 | 0.0 | ||||||||||||||
1eer | 2 | P19235 | 98.22 | 3e-156 |
X-RAY |
1999-10-01 | PRO | B:216 | B:215 | 79.0 | 0.545 | -78.9 | 170.3 | 79.0 | 0.545 | 0.0 |
HOH |
4.000 |
CG |
O |
|||
PRO | C:216 | C:215 | 73.0 | 0.503 | -74.3 | 167.1 | 73.0 | 0.503 | 0.0 |
HOH |
3.991 |
CG |
O |
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4y5v | 3 | P19235 | 99.08 | 7e-155 |
X-RAY |
2015-04-29 | PRO | C:213 | C:215 | 82.0 | 0.566 | -76.6 | 156.6 | 82.0 | 0.566 | 0.0 |
HOH |
4.691 |
N |
O |
|||
PRO | F:213 | F:215 | 83.0 | 0.572 | -76.4 | 158.4 | 83.0 | 0.572 | 0.0 |
GOL HOH |
7.611 6.466 |
O CB |
C3 O |
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PRO | I:213 | I:215 | 87.0 | 0.6 | -77.1 | 156.5 | NA | NA | NA | ||||||||||||||
4y5x | 3 | P19235 | 99.08 | 7e-155 |
X-RAY |
2015-03-18 | PRO | C:213 | C:215 | 72.0 | 0.497 | -63.5 | 155.8 | 72.0 | 0.497 | 0.0 |
PEG |
5.211 |
CB |
C1 |
|||
PRO | F:213 | F:215 | 83.0 | 0.572 | -63.4 | 156.1 | NA | NA | NA | ||||||||||||||
PRO | I:213 | I:215 | 74.0 | 0.51 | -63.6 | 155.7 | NA | NA | NA | ||||||||||||||
PRO | L:213 | L:215 | 75.0 | 0.517 | -64.1 | 155.5 | 75.0 | 0.517 | 0.0 |
PEG HOH |
4.965 6.822 |
CB CB |
C4 O |
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6moe | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | PRO | C:213 | C:215 | 79.0 | 0.545 | -79.5 | 160.8 | NA | NA | NA | |||||||
PRO | D:213 | D:215 | 76.0 | 0.524 | -79.6 | 162.3 | 76.0 | 0.524 | 0.0 |
HOH |
4.257 |
O |
O |
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6mof | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | PRO | B:213 | B:215 | 84.0 | 0.579 | -72.8 | 160.8 | 84.0 | 0.579 | 0.0 |
HOH |
6.985 |
CB |
O |
|||
6moh | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | PRO | C:213 | C:215 | 77.0 | 0.531 | -68.6 | 151.8 | 77.0 | 0.531 | 0.0 | |||||||
PRO | D:213 | D:215 | 75.0 | 0.517 | -69.8 | 152.0 | 75.0 | 0.517 | 0.0 | ||||||||||||||
6moi | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | PRO | B:213 | B:215 | 73.0 | 0.503 | -86.4 | 161.2 | 73.0 | 0.503 | 0.0 |
HOH |
3.668 |
O |
O |
|||
6moj | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | PRO | B:213 | B:215 | 78.0 | 0.538 | -82.5 | 165.3 | 78.0 | 0.538 | 0.0 |
GOL GOL HOH |
4.899 9.840 9.092 |
CB CG CB |
O1 O1 O |
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6mok | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | PRO | B:213 | B:215 | 77.0 | 0.531 | -80.6 | 149.5 | 77.0 | 0.531 | 0.0 | |||||||
6mol | 2 | P19235 | 99.08 | 7e-155 |
X-RAY |
2019-06-05 | PRO | B:213 | B:215 | 81.0 | 0.559 | -64.9 | 147.4 | 81.0 | 0.559 | 0.0 | |||||||
PRO | C:213 | C:215 | 79.0 | 0.545 | -65.2 | 146.5 | 79.0 | 0.545 | 0.0 | ||||||||||||||
1eba | 1 | P19235 | 100.0 | 2e-153 |
X-RAY |
1998-11-11 | PRO | A:206 | A:215 | 81.0 | 0.559 | -85.8 | 173.2 | 81.0 | 0.559 | 0.0 | |||||||
PRO | B:206 | B:215 | 65.0 | 0.448 | -78.7 | 172.1 | 65.0 | 0.448 | 0.0 | ||||||||||||||
4y5y | 3 | P19235 | 99.07 | 3e-152 |
X-RAY |
2015-03-18 | PRO | C:213 | C:215 | 90.0 | 0.621 | -62.5 | 152.8 | 90.0 | 0.621 | 0.0 | |||||||
PRO | F:213 | F:215 | 88.0 | 0.607 | -63.1 | 151.7 | 88.0 | 0.607 | 0.0 | ||||||||||||||
1ern | 1 | P19235 | 100.0 | 8e-152 |
X-RAY |
2000-01-07 | PRO | A:206 | A:215 | 74.0 | 0.51 | -63.9 | 174.4 | 74.0 | 0.51 | 0.0 |
HOH |
4.608 |
CG |
O |
|||
PRO | B:206 | B:215 | 83.0 | 0.572 | -68.0 | 162.4 | 83.0 | 0.572 | 0.0 |
HOH |
6.214 |
N |
O |
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1ebp | 1 | P19235 | 100.0 | 1e-150 |
X-RAY |
1997-07-29 | PRO | A:206 | A:215 | 60.0 | 0.414 | -85.5 | 167.0 | 60.0 | 0.414 | 0.0 | |||||||
PRO | B:206 | B:215 | 87.0 | 0.6 | -55.7 | 158.2 | 87.0 | 0.6 | 0.0 | ||||||||||||||
2mv6 | 1 | P19235 | 100.0 | 1e-08 |
NMR |
2014-12-10 | PRO | A:4 | A:4 | 71.0 | 0.49 | G | -66.1 | -15.9 | 71.0 | 0.49 | 0.0 | ||||||
2mxb | 1 | P14753 | 85.42 | 9e-07 |
NMR |
2015-09-23 | PRO | A:4 | A:4 | 87.0 | 0.6 | -70.9 | 138.1 | 87.0 | 0.6 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p19235-f1 | 1 | P19235 | 100.0 | 0.0 | PRO | A:239 | A:239 | 80.0 | 0.552 | -75.7 | 142.0 |