Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr19 11491774 . A C CCDS12260.1:NM_000121.3:c.697Tgg>Ggg_NP_000112.1:p.233W>G Homo sapiens erythropoietin receptor (EPOR), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2jix 2 P19235 100.0 5e-161 X-RAY
 2007-07-10 TRP B:209 B:209 41.0 0.161 -59.5 147.5 NA NA NA
TRP C:209 C:209 38.0 0.149 -59.3 135.6 38.0 0.149 0.0
TRP E:209 E:209 46.0 0.18 -75.1 152.0 NA NA NA
1cn4 1 P19235 98.23 9e-159 X-RAY
 1999-08-11 TRP A:212 A:209 56.0 0.22 -46.8 151.4 56.0 0.22 0.0
TRP B:212 B:209 33.0 0.129 -71.8 128.6 33.0 0.129 0.0 HOH
 2.456
 N
 O
1eer 2 P19235 98.22 3e-156 X-RAY
 1999-10-01 TRP B:210 B:209 42.0 0.165 -59.1 131.4 42.0 0.165 0.0 HOH
 4.006
 C
 O
TRP C:210 C:209 31.0 0.122 -53.2 144.3 31.0 0.122 0.0 HOH
 3.163
 N
 O
4y5v 3 P19235 99.08 7e-155 X-RAY
 2015-04-29 TRP C:207 C:209 29.0 0.114 -64.1 134.9 29.0 0.114 0.0 HOH
 3.202
 N
 O
TRP F:207 F:209 32.0 0.125 -64.1 135.8 32.0 0.125 0.0 HOH
 2.670
 NE1
 O
TRP I:207 I:209 56.0 0.22 -64.2 135.7 NA NA NA
4y5x 3 P19235 99.08 7e-155 X-RAY
 2015-03-18 TRP C:207 C:209 58.0 0.227 -67.7 135.1 41.0 0.161 0.066 L:P19235:0.067
 PEG
 4.004
 CD1
 C3
TRP F:207 F:209 60.0 0.235 -67.2 135.7 NA NA NA
TRP I:207 I:209 49.0 0.192 -67.4 134.7 NA NA NA
TRP L:207 L:209 51.0 0.2 -67.4 135.9 40.0 0.157 0.043 C:P19235:0.043
 PEG
 5.029
 CD1
 C2
6moe 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 TRP C:207 C:209 30.0 0.118 -67.2 146.7 NA NA NA
TRP D:207 D:209 61.0 0.239 -78.8 146.8 61.0 0.239 0.0 HOH
 2.720
 N
 O
6mof 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 TRP B:207 B:209 46.0 0.18 -64.6 146.9 46.0 0.18 0.0
6moh 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 TRP C:207 C:209 28.0 0.11 -70.9 134.9 28.0 0.11 0.0
TRP D:207 D:209 31.0 0.122 -70.0 134.3 31.0 0.122 0.0
6moi 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 TRP B:207 B:209 40.0 0.157 -67.1 149.0 40.0 0.157 0.0 SO4
MG
HOH
 5.665
4.394
3.825
 CD1
CD1
C
 O3
MG
O
6moj 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 TRP B:207 B:209 28.0 0.11 -59.7 138.9 28.0 0.11 0.0 GOL
HOH
 5.789
4.203
 CD1
CD1
 O2
O
6mok 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 TRP B:207 B:209 31.0 0.122 -66.0 140.5 31.0 0.122 0.0
6mol 2 P19235 99.08 7e-155 X-RAY
 2019-06-05 TRP B:207 B:209 43.0 0.169 -68.8 141.2 43.0 0.169 0.0
TRP C:207 C:209 46.0 0.18 -69.6 140.8 46.0 0.18 0.0
1eba 1 P19235 100.0 2e-153 X-RAY
 1998-11-11 TRP A:200 A:209 62.0 0.243 -72.4 145.7 62.0 0.243 0.0
TRP B:200 B:209 53.0 0.208 -75.6 137.4 53.0 0.208 0.0
4y5y 3 P19235 99.07 3e-152 X-RAY
 2015-03-18 TRP C:207 C:209 60.0 0.235 -68.1 151.7 60.0 0.235 0.0 HOH
 5.548
 O
 O
TRP F:207 F:209 47.0 0.184 -67.4 152.3 47.0 0.184 0.0 HOH
 5.216
 O
 O
1ern 1 P19235 100.0 8e-152 X-RAY
 2000-01-07 TRP A:200 A:209 70.0 0.275 -70.1 142.3 70.0 0.275 0.0 HOH
 3.807
 C
 O
TRP B:200 B:209 39.0 0.153 -75.5 144.6 39.0 0.153 0.0 HOH
 2.779
 O
 O
1ebp 1 P19235 100.0 1e-150 X-RAY
 1997-07-29 TRP A:200 A:209 69.0 0.271 -68.1 142.3 69.0 0.271 0.0
TRP B:200 B:209 80.0 0.314 -60.1 126.1 80.0 0.314 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19235-f1 1 P19235 100.0 0.0 TRP A:233 A:233 31.0 0.122 -60.9 132.8